Gene

KWMTBOMO07060

Pre Gene Modal

BGIBMGA010521

Annotation

PREDICTED:_cGMP-dependent_3'?5'-cyclic_phosphodiesterase-like_[Bombyx_mori]

Location

Bomo_Chr12(+):2947665-2955466      View in EpiBrowser

Full name

Phosphodiesterase      

Location in the cell

Cytoplasmic   Reliability : 2.001 PlasmaMembrane   Reliability : 1.475

CDS

ATGTTACATTTTAGAACGATCCTTTGCTTTCCCATACGGGAGCAGACCGGAATAATAGGCGTGGGGCAACTCATTAACAAGATCGGCGATCCATACTTCGACGCAATGGACGAGGAAATGGCGCTGGCGTTTAGTGTCTATTGCGGCATATGTATCATACATTCCGTGGTCTATCAGAAAATACAAGAAGCCCACATCAGGAACACGCTGGCTATAGAACTCGTCATGTACCATATGAAGGTGGGTGACGCTGAAGTAAACCGTCTAACTCAATGTACCGGCTTCCACAGCCACCCACACTTGACCAGTCTCCATTTCAATCCGAGGGCCCTTTCCCTCAGAGAACTTCCTTGTTACGTTATGAAGATTTTCGTTGATCTCGGCTTCGAGAAAAAATTCAACATTAAAAGCCAGAAACTGGCCCGTTTCATATTGTACGCCAAGAAGGGGTATCGCGATGTGCCCTATCACAACTGGCTTCATGCGTTCAACGTAACTCAGTGGGCATACGCTGCTCTCGTCAACTTCAAACTTGTACAACAAGGTTACTTGACGGAACTACAAGCCTTGATGTACTTGGTCGCTGGTCTGGTACACGACCTGGATCACCGTGGGACCACTAACAGCTTTCATATACAAGGACAGACCACATTAGCGGCCTTGTATTCGAGCGAAAGTAGCGTGATGGAACGGCACCACTTGGCCCAGGCCATGTGCATCTTGAACACGGAAGGATGCGACATCCTCGAATCGTTACCGAGAAAGGATTACGACAGAGCGATCCTGATGCTCAGAGATTACATCCTGGCGACGGACTTGTCTAATTACTTTAAGAACCTAAGCGAATACAAATCGATATCCCAGGATTATTTGAAGGGTAACCGCGCCCACGTGTCGTGTCTACAGGCGTTGCTAATGAACGCCGCCGACCTCAGCGACCAGCTTAAAGACTGGGCCAGTGTCAAGAAGACCGCAGCGTCAGTGCTGACGGAGTTCTTCAAGCAGGGCGACGTGGAGAAGAGCCGCGGCGACCTCCCGCTGCTGATGATGGACCGCGAAAAATGCTTCATACCGCAACTAGAGATACAGTTCATGCAGACCACATGCGTGCCGCTCTTTGAGACTTTAGGTAGAATTATACCCAAAGCCACTGTGTGTGTGAAGATCATTGAGAGCCATATCGAGAGGTGGGAGGCCGCCAAACCAATTTTTGCTGAGGTAATAAATACTATTTTTTAG

Protein

MLHFRTILCFPIREQTGIIGVGQLINKIGDPYFDAMDEEMALAFSVYCGICIIHSVVYQKIQEAHIRNTLAIELVMYHMKVGDAEVNRLTQCTGFHSHPHLTSLHFNPRALSLRELPCYVMKIFVDLGFEKKFNIKSQKLARFILYAKKGYRDVPYHNWLHAFNVTQWAYAALVNFKLVQQGYLTELQALMYLVAGLVHDLDHRGTTNSFHIQGQTTLAALYSSESSVMERHHLAQAMCILNTEGCDILESLPRKDYDRAILMLRDYILATDLSNYFKNLSEYKSISQDYLKGNRAHVSCLQALLMNAADLSDQLKDWASVKKTAASVLTEFFKQGDVEKSRGDLPLLMMDREKCFIPQLEIQFMQTTCVPLFETLGRIIPKATVCVKIIESHIERWEAAKPIFAEVINTIF

Cofactor

a divalent metal cation

Similarity

Belongs to the cyclic nucleotide phosphodiesterase family.

Feature

chain  Phosphodiesterase

Uniprot

A0A3S2M662   A0A212ETA5   A0A2W1BL24   A0A2A4J9P4   A0A2H1VME5   H9JLW9   + More
A0A194QTM5   A0A194PHP8   E2B075   A0A0C9PJJ3   A0A026WWF1   A0A0C9R2P4   A0A232FAD7   K7JCC9   E2BF09   A0A0T6B7C6   A0A2J7PMS4   A0A154NW39   A0A2J7PMS8   A0A0L7R674   A0A2J7PMS2   A0A1B6IC31   A0A310SNS7   A0A2A3EGP5   T1J3H1   A0A0N1ITS8   A0A088A252   A0A0P5NIS5   A0A1E1XUD1   A0A023FMQ8   A0A1W4W5Z9   A0A0N8CSS7   A0A0P5UW29   A0A0S7JL69   A0A1E1X7H1   A0A0P5Q2F8   A0A0P5RND4   A0A023GL03   A0A0P5V3J9   A0A0P5TMC9   A0A0P5W3Z5   A0A0P6F8D5   A0A0P6B0Z3   A0A0P6HAH8   A0A131XIN4   A0A0P5QV76   A0A164STZ7   A0A1Y1L2W4   E9FT33   G3NY20   L7MAG8   A0A0S7JJR0   A0A3B5QRE6   A0A0P4Y5N3   A0A315VBS5   A0A131Y3H4   B7Q413   M4A9D2   A0A3Q3LH85   A0A3Q3L5V4   A0A3Q2ZF50   A0A3Q3L4B5   A0A0P5Q429   A0A131Z005   A0A3Q2ZVA7   A0A096MAA2   A0A3P9Q220   A0A0K2T0H8   A0A3B3BA57   A0A2D0SU57   A0A1A8D2S2   A0A1A8AZE0   A0A1A8FPZ9   A0A3P9Q2E1   A0A1A8KRC5   A0A1A8D800   A0A1A8GCD1   A0A1A8SE87   A0A1A8Q921   A0A1Z5L6I7   A0A1A8I6C9   A0A1A8RDU4   A0A3P9Q1Y2   A0A3P9Q1C2   A0A147AHK6   A0A3S2PM84   A0A3Q2SRM1   A0A2R5L7V9   A0A1W4ZTM1   A0A224YJQ4   A0A3Q2SRN0   A0A1W4ZK77   A0A146XH68   A0A2I4C0W7   A0A0C9QKJ1   A0A3P9INJ5   A0A3P9L0E8   A0A3P9JUA1   A0A3N0Z8C8   A0A1A7YMM6  

EC Number

3.1.4.-

Pubmed

22118469    28756777    19121390    26354079    20798317    24508170    + More
30249741    28648823    20075255    29209593    28503490    28049606    28004739    21292972    25576852    23542700    29703783    26830274    29451363    28528879    28797301    17554307   

EMBL

RSAL01000028    RVE51872.1    AGBW02012613    OWR44723.1    KZ150015    PZC74981.1    + More
NWSH01002283    PCG68681.1    ODYU01003339    SOQ41966.1    BABH01005299    KQ461194    KPJ06896.1    KQ459603    KPI92941.1    GL444408    EFN60932.1    GBYB01001118    JAG70885.1    KK107078    QOIP01000011    EZA60382.1    RLU16923.1    GBYB01001116    JAG70883.1    NNAY01000569    OXU27625.1    GL447903    EFN85732.1    LJIG01009614    KRT82727.1    NEVH01023960    PNF17626.1    KQ434772    KZC03886.1    PNF17627.1    KQ414648    KOC66276.1    PNF17625.1    GECU01023231    JAS84475.1    KQ762237    OAD55997.1    KZ288260    PBC30462.1    JH431826    KQ435750    KOX76378.1    GDIQ01163957    JAK87768.1    GFAA01000530    JAU02905.1    GBBK01002317    JAC22165.1    GDIP01102431    JAM01284.1    GDIP01107882    JAL95832.1    GBYX01237290    JAO65442.1    GFAC01003961    JAT95227.1    GDIQ01126677    JAL25049.1    GDIQ01098388    JAL53338.1    GBBM01000846    JAC34572.1    GDIP01105288    JAL98426.1    GDIP01141842    JAL61872.1    GDIP01105289    JAL98425.1    GDIQ01052559    JAN42178.1    GDIP01021964    JAM81751.1    GDIQ01022314    JAN72423.1    GEFH01003065    JAP65516.1    GDIQ01129433    JAL22293.1    LRGB01001937    KZS09939.1    GEZM01066253    JAV68033.1    GL732524    EFX89300.1    GACK01004935    JAA60099.1    GBYX01237294    JAO65439.1    GDIP01232283    JAI91118.1    NHOQ01001971    PWA20266.1    GEFM01002774    JAP73022.1    ABJB010079164    ABJB010536083    DS853260    EEC13588.1    GDIQ01129434    JAL22292.1    GEDV01004435    JAP84122.1    AYCK01010018    AYCK01010019    AYCK01010020    HACA01001949    CDW19310.1    HADZ01021607    SBP85548.1    HADY01021573    HAEJ01003272    SBP60058.1    HAEB01013682    SBQ60209.1    HAEE01014975    SBR35025.1    HAEA01000993    SBQ29473.1    HAEC01000619    SBQ68696.1    HAEI01014177    SBS16646.1    HAEF01012525    HAEG01011632    SBR90260.1    GFJQ02004162    JAW02808.1    HAED01006147    SBQ92177.1    HAEH01016241    SBS04226.1    GCES01008402    JAR77921.1    CM012449    RVE64621.1    GGLE01001419    MBY05545.1    GFPF01006710    MAA17856.1    GCES01045329    JAR40994.1    GBYB01001117    JAG70884.1    RJVU01006538    ROL54707.1    HADW01006615    HADX01009201    SBP31433.1   

Proteomes

UP000283053    UP000007151    UP000218220    UP000005204    UP000053240    UP000053268    + More
UP000000311    UP000053097    UP000279307    UP000215335    UP000002358    UP000008237    UP000235965    UP000076502    UP000053825    UP000242457    UP000053105    UP000005203    UP000192223    UP000076858    UP000000305    UP000007635    UP000002852    UP000001555    UP000261640    UP000264800    UP000028760    UP000242638    UP000261560    UP000221080    UP000265000    UP000192224    UP000192220    UP000265200    UP000265180   

PRIDE

H9JLW9   

Pfam

PF00233   PDEase_I        + More
PF13185   GAF_2
PF01590   GAF
PF03941   INCENP_ARK-bind

Interpro

IPR036971   PDEase_catalytic_dom_sf        + More
IPR003607   HD/PDEase_dom       
IPR002073   PDEase_catalytic_dom       
IPR029016   GAF-like_dom_sf       
IPR023088   PDEase       
IPR003018   GAF       
IPR023174   PDEase_CS       
IPR005635   Inner_centromere_prot_ARK-bd       

Gene 3D

1.10.1300.10     3.30.450.40    

CDD

cd00077  HDc

ProteinModelPortal

A0A3S2M662   A0A212ETA5   A0A2W1BL24   A0A2A4J9P4   A0A2H1VME5   H9JLW9   + More
A0A194QTM5   A0A194PHP8   E2B075   A0A0C9PJJ3   A0A026WWF1   A0A0C9R2P4   A0A232FAD7   K7JCC9   E2BF09   A0A0T6B7C6   A0A2J7PMS4   A0A154NW39   A0A2J7PMS8   A0A0L7R674   A0A2J7PMS2   A0A1B6IC31   A0A310SNS7   A0A2A3EGP5   T1J3H1   A0A0N1ITS8   A0A088A252   A0A0P5NIS5   A0A1E1XUD1   A0A023FMQ8   A0A1W4W5Z9   A0A0N8CSS7   A0A0P5UW29   A0A0S7JL69   A0A1E1X7H1   A0A0P5Q2F8   A0A0P5RND4   A0A023GL03   A0A0P5V3J9   A0A0P5TMC9   A0A0P5W3Z5   A0A0P6F8D5   A0A0P6B0Z3   A0A0P6HAH8   A0A131XIN4   A0A0P5QV76   A0A164STZ7   A0A1Y1L2W4   E9FT33   G3NY20   L7MAG8   A0A0S7JJR0   A0A3B5QRE6   A0A0P4Y5N3   A0A315VBS5   A0A131Y3H4   B7Q413   M4A9D2   A0A3Q3LH85   A0A3Q3L5V4   A0A3Q2ZF50   A0A3Q3L4B5   A0A0P5Q429   A0A131Z005   A0A3Q2ZVA7   A0A096MAA2   A0A3P9Q220   A0A0K2T0H8   A0A3B3BA57   A0A2D0SU57   A0A1A8D2S2   A0A1A8AZE0   A0A1A8FPZ9   A0A3P9Q2E1   A0A1A8KRC5   A0A1A8D800   A0A1A8GCD1   A0A1A8SE87   A0A1A8Q921   A0A1Z5L6I7   A0A1A8I6C9   A0A1A8RDU4   A0A3P9Q1Y2   A0A3P9Q1C2   A0A147AHK6   A0A3S2PM84   A0A3Q2SRM1   A0A2R5L7V9   A0A1W4ZTM1   A0A224YJQ4   A0A3Q2SRN0   A0A1W4ZK77   A0A146XH68   A0A2I4C0W7   A0A0C9QKJ1   A0A3P9INJ5   A0A3P9L0E8   A0A3P9JUA1   A0A3N0Z8C8   A0A1A7YMM6  

PDB

3IBJ     E-value=4.18279e-98,     Score=914

KEGG

101740240    K18283 cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17] | (RefSeq) cGMP-dependent 3',5'-c

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0046872   GO:0016787   GO:0007165   GO:0004114   GO:0004115   GO:0005829   GO:0043951   GO:0005743   GO:0005759   GO:0019934   GO:0005634   GO:0004118   GO:0010821   GO:0010628   GO:0019933   GO:0046069   GO:0005741   GO:0010754   GO:0030552   GO:0047555   GO:0042803   GO:0030553   GO:0048471   GO:0005840   GO:0008081   GO:0008270   GO:0005515   GO:0004319   GO:0004320   GO:0016295   GO:0016296  

Length:

412

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.43549000000001

Exp number, first 60 AAs:

2.89499

Total prob of N-in:

0.04344

outside

1  -  412

 

 

Pi

273.645265

Theta

194.355985

Tajima's D

0.784839

CLR

0.056055

CSRT

0.602269886505675

Interpretation

Uncertain