Gene

KWMTBOMO07036

Annotation

PREDICTED:_putative_fatty_acyl-CoA_reductase_CG5065_[Bombyx_mori]

Location

Bomo_Chr12(+):2282510-2292908      View in EpiBrowser

Full name

Fatty acyl-CoA reductase       + More
Putative fatty acyl-CoA reductase CG5065      

Location in the cell

Mitochondrial   Reliability : 2.087

CDS

ATGGCTGCTCTGCTGAACAATTCTATTTTTGGAAAGTTAAAAGCCTTGAAGCCGTCCGCAGTAAGCAAAATAGTGCCTATATATGGCGACGTCACGCAAACCGACTTGGCCATGAAAACACAAGACATTAAAACGTTAACCTCAGAGGTTTCGGTGGTTTTTCATATGGCTGCAAGTATACAGTTCAAAGAACCTATGTCTGTTACCCTGAATTACAACTATGAGGGGACGAAGAGAGTACTTAAGTTATTACGGCAAATGCAAAAGATTGAATCCTTCGTTCACGTTTCGTCTGTATATGCACAAGCGCTTGATGGAGGGAAGATAGTTAAGGAGACCTTGTACCCGCCGCCGGCTAATCACAACGAACTAGAGACCTTCATATCGAAGTACGACAACGACGAAGAGGAAACAAAGAAATTTTTGCAACGACGTTGTAATACATACGCTTATGGTAAAGCGTTGACAGAGGTCTTTGTGGCTGAAAACCATGGCACGATACCGACATGCATAGTTAGACCATCTATGATTACTTCGAAAGCAGAGCAGCCTTTACCTGGTTGGTTAGACAACTGGTATGGACCGACGCGCTTCTTATACAATGCATCTCGTGGATGGGATCGTTCGTGCTTCATTCGAAGAGAATTCTTAGTTGACATGATACCAGTGGACTATGTCGCGAACCTCTGTATCGTTGCGGGAGCGAGAAACGACAGTTGTGTCGATGTCGCGGTTTTCAACAGTTGTACCACAGGAGCGAATCCATTAACCTGGGCATATGCACATAAGTGCATGATAAAAGATACAGTTAAGAATAAATTGAATGATCTGCCATATCCATTTGTATTATACACACAGTCAAAGCTACTATACTCAATTTATACGATGCTTCTGCAGTTAATTCCTGCAAAAATAGCGGACGGTTGGCTGTGGGTTACTGGAAGGAGATCAAAGTATACAAAAACACAGAAGAAAGTAATACATTTAAAAGAAACACTGAGTTTTTTTCTGAAGAATTCATGGGTAATTGAATGCGAAAATACTAGGAAACTCTTTAGATCTCTATCATTGGATGATCAAAAAAAGTTTCCCTGTGACCCCGTTAACATTAACTGGAGAAAATACTTAGAAGACTATCAAAAGGGCATCGAAAAGTTTTTGTGCCAGGAAAAAGTGGGGCCAAATAAACCTTAA

Protein

MAALLNNSIFGKLKALKPSAVSKIVPIYGDVTQTDLAMKTQDIKTLTSEVSVVFHMAASIQFKEPMSVTLNYNYEGTKRVLKLLRQMQKIESFVHVSSVYAQALDGGKIVKETLYPPPANHNELETFISKYDNDEEETKKFLQRRCNTYAYGKALTEVFVAENHGTIPTCIVRPSMITSKAEQPLPGWLDNWYGPTRFLYNASRGWDRSCFIRREFLVDMIPVDYVANLCIVAGARNDSCVDVAVFNSCTTGANPLTWAYAHKCMIKDTVKNKLNDLPYPFVLYTQSKLLYSIYTMLLQLIPAKIADGWLWVTGRRSKYTKTQKKVIHLKETLSFFLKNSWVIECENTRKLFRSLSLDDQKKFPCDPVNINWRKYLEDYQKGIEKFLCQEKVGPNKP

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Catalyzes the reduction of C16 or C18 fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Keywords

Complete proteome   Lipid biosynthesis   Lipid metabolism   Membrane   NADP   Oxidoreductase   Peroxisome   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Putative fatty acyl-CoA reductase CG5065

Uniprot

A0A2A4JQ58   A0A2W1B441   A0A2H1VMP7   A0A2H1VWL8   A0A212EK35   A0A068FRD8   + More
A0A194PI13   A0A2A4J0C7   W5QMH3   A0A194QNF1   I3PN84   A0A194PI08   A0A291P0W0   I3PN85   A0A291P0K3   A0A0N7IQX9   A0A1V0M878   A0A0P0IV71   W5QM70   A0A0F6Q4M2   D2SNU9   I3PN86   A0A0P0I5I6   A0A090C638   A0A194QMY3   A0A0P0ES22   A0A068FL32   A0A212EK03   A0A1V0M885   A0A0F6NS86   A0A1V0M875   A0A076FRK0   U5KFM8   D7P5E6   D7P5E5   A0A2H1W6U5   D7P5E3   Q7YTA9   H9JLQ6   A0A194PP95   Q7YTA8   A0A2A4JCF9   A0A023F1V0   D2A660   A0A1L8D6A3   A0A224XJF5   A0A069DV62   A0A2J7PLY4   V5GSY3   A0A067R949   A0A3Q8FTW8   E0VLJ7   A0A3S3P4D3   A0A0A9WTX4   A0A336LRW3   A0A310SYR9   A0A1Z3FT38   A0A336MZZ9   A0A1B6JB63   E0VSV6   A0A1B6KYT4   A0A067RBR1   A0A226E5U8   A0A1B6GUZ4   T1KB77   A0A2J7PM67   B4JWM8   A0A1B6CB27   A0A1A9X2G9   A0A0M4EVU9   A0A2L2YHA0   B4LPA3   A0A0P6I2I8   A0A1B0G7W2   A0A0P6CJQ1   A0A212F418   A0A0A9VYR3   A0A1B0ARC3   A0A0A9VVQ7   A0A1A9VQ82   B4MIU8   B3MDK3   B4KSN0   A0A2A4JJ98   E9J0E5   E2B9J0   A0A2H1VLB8   E1JH83   A1ZAI5   B4HT68   A0A0C9QJE0   A0A0J9RE92   B3NPG3   A0A1W4UXP9   A0A2S2R203   A0A1W4WEK2   B4P5X9   A0A1A9XXW3   A0A3B0J1M1  

EC Number

1.2.1.84

Pubmed

28756777    22118469    26385554    26354079    24862548    22615947    + More
28986331    27427355    28349297    20074338    25558806    26445454    24817326    24053512    20534481    12871998    19121390    25474469    18362917    19820115    26334808    24845553    20566863    25401762    26823975    28608990    17994087    26561354    18057021    21282665    20798317    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    17550304   

EMBL

NWSH01000832    PCG73949.1    KZ150367    PZC71169.1    ODYU01003396    SOQ42100.1    + More
ODYU01004894    SOQ45237.1    AGBW02014338    OWR41841.1    KJ622067    AID66655.1    KQ459603    KPI92957.1    NWSH01004349    PCG65196.1    JQ978770    AGD98718.1    KQ461194    KPJ06884.1    JF709976    AFD04726.1    KPI92952.1    MF687590    ATJ44516.1    JF709977    KP237931    AFD04727.1    AKD01784.1    MF687545    ATJ44471.1    KR781119    ALJ94059.1    KU755478    ARD71188.1    KR781121    ALJ94061.1    JQ978771    AGD98719.1    KP237920    AKD01773.1    EZ407233    ACX53790.1    JF709978    AFD04728.1    KR781120    ALJ94060.1    HG423128    CDG50833.1    KPJ06882.1    KT261697    ALJ30237.1    JX679210    KJ622060    AGP26039.1    AID66648.1    OWR41842.1    KU755484    ARD71194.1    KF805977    AIS85928.1    KU755477    ARD71187.1    KF960748    AII21950.1    JX989164    AGR49323.1    GQ907235    ADD62442.1    GQ907234    ADD62441.1    ODYU01006707    SOQ48800.1    GQ907232    ADD62439.1    AB104896    BAC79425.1    BABH01005237    KPI92955.1    AB104897    BAC79426.1    NWSH01002009    PCG69446.1    GBBI01003721    JAC14991.1    KQ971346    EFA04974.1    GEYN01000140    JAV01989.1    GFTR01006468    JAW09958.1    GBGD01001183    JAC87706.1    NEVH01024421    PNF17348.1    GALX01005113    JAB63353.1    KK852807    KDR16086.1    MG573164    AWJ25026.1    DS235271    EEB14253.1    NCKU01000661    RWS14634.1    GBHO01033661    GBHO01033660    GBRD01008049    GBRD01008048    GBRD01008047    GDHC01019056    GDHC01002516    JAG09943.1    JAG09944.1    JAG57772.1    JAP99572.1    JAQ16113.1    UFQT01000095    SSX19701.1    KQ759773    OAD62927.1    KY274178    ASC44542.1    UFQT01004920    SSX35816.1    GECU01011206    JAS96500.1    DS235758    EEB16462.1    GEBQ01023412    JAT16565.1    KDR16085.1    LNIX01000006    OXA53032.1    GECZ01003528    JAS66241.1    CAEY01001946    PNF17417.1    CH916375    EDV98366.1    GEDC01026600    JAS10698.1    CP012524    ALC42075.1    IAAA01029277    IAAA01029278    LAA07536.1    CH940648    EDW60212.2    GDIQ01010511    JAN84226.1    CCAG010021504    GDIP01000129    JAN03587.1    AGBW02010466    OWR48453.1    GBHO01043288    GBRD01007683    JAG00316.1    JAG58138.1    JXJN01002319    JXJN01002320    GBHO01043282    JAG00322.1    CH963719    EDW72037.1    CH902619    EDV37466.1    KPU76846.1    CH933808    EDW10529.2    NWSH01001298    PCG71798.1    GL767462    EFZ13704.1    GL446556    EFN87623.1    ODYU01003002    SOQ41212.1    AE013599    ACZ94440.1    AAF57974.1    CH480816    EDW48169.1    GBYB01014923    GBYB01014924    JAG84690.1    JAG84691.1    CM002911    KMY94302.1    CH954179    EDV55730.1    GGMS01014761    MBY83964.1    CM000158    EDW91895.1    OUUW01000001    SPP72772.1   

Proteomes

UP000218220    UP000007151    UP000053268    UP000053240    UP000005204    UP000007266    + More
UP000235965    UP000027135    UP000009046    UP000285301    UP000198287    UP000015104    UP000001070    UP000091820    UP000092553    UP000008792    UP000092444    UP000092460    UP000078200    UP000007798    UP000007801    UP000009192    UP000008237    UP000000803    UP000001292    UP000008711    UP000192221    UP000192223    UP000002282    UP000092443    UP000268350   

PRIDE

Q7YTA9    H9JLQ6    Q7YTA8    A1ZAI5   

Pfam

PF07993   NAD_binding_4        + More
PF03015   Sterile

Interpro

IPR036291   NAD(P)-bd_dom_sf        + More
IPR013120   Male_sterile_NAD-bd       
IPR033640   FAR_C       
IPR026055   FAR       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

A0A2A4JQ58   A0A2W1B441   A0A2H1VMP7   A0A2H1VWL8   A0A212EK35   A0A068FRD8   + More
A0A194PI13   A0A2A4J0C7   W5QMH3   A0A194QNF1   I3PN84   A0A194PI08   A0A291P0W0   I3PN85   A0A291P0K3   A0A0N7IQX9   A0A1V0M878   A0A0P0IV71   W5QM70   A0A0F6Q4M2   D2SNU9   I3PN86   A0A0P0I5I6   A0A090C638   A0A194QMY3   A0A0P0ES22   A0A068FL32   A0A212EK03   A0A1V0M885   A0A0F6NS86   A0A1V0M875   A0A076FRK0   U5KFM8   D7P5E6   D7P5E5   A0A2H1W6U5   D7P5E3   Q7YTA9   H9JLQ6   A0A194PP95   Q7YTA8   A0A2A4JCF9   A0A023F1V0   D2A660   A0A1L8D6A3   A0A224XJF5   A0A069DV62   A0A2J7PLY4   V5GSY3   A0A067R949   A0A3Q8FTW8   E0VLJ7   A0A3S3P4D3   A0A0A9WTX4   A0A336LRW3   A0A310SYR9   A0A1Z3FT38   A0A336MZZ9   A0A1B6JB63   E0VSV6   A0A1B6KYT4   A0A067RBR1   A0A226E5U8   A0A1B6GUZ4   T1KB77   A0A2J7PM67   B4JWM8   A0A1B6CB27   A0A1A9X2G9   A0A0M4EVU9   A0A2L2YHA0   B4LPA3   A0A0P6I2I8   A0A1B0G7W2   A0A0P6CJQ1   A0A212F418   A0A0A9VYR3   A0A1B0ARC3   A0A0A9VVQ7   A0A1A9VQ82   B4MIU8   B3MDK3   B4KSN0   A0A2A4JJ98   E9J0E5   E2B9J0   A0A2H1VLB8   E1JH83   A1ZAI5   B4HT68   A0A0C9QJE0   A0A0J9RE92   B3NPG3   A0A1W4UXP9   A0A2S2R203   A0A1W4WEK2   B4P5X9   A0A1A9XXW3   A0A3B0J1M1  

PDB

4W4T     E-value=6.10785e-05,     Score=111

KEGG

105842124    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) putative fatty acyl-CoA red

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0006629   GO:0080019   GO:0102965   GO:0016021   GO:0005783   GO:0005777   GO:0035336   GO:0010025   GO:0005778   GO:0008611   GO:0005779   GO:0016301  

PANTHER

PTHR11011  

Subcellular location

Peroxisome membrane  

Length:

397

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

5.09848000000001

Exp number, first 60 AAs:

0.00194

Total prob of N-in:

0.00532

outside

1  -  397

 

 

Pi

168.822715

Theta

133.155482

Tajima's D

0.588433

CLR

0.200042

CSRT

0.541122943852807

Interpretation

Uncertain