Gene

KWMTBOMO07032

Pre Gene Modal

BGIBMGA010457

Annotation

PREDICTED:_fatty_acyl-CoA_reductase_1-like_[Papilio_machaon]

Location

Bomo_Chr12(-):2201055-2227809      View in EpiBrowser

Full name

Fatty acyl-CoA reductase       + More
Putative fatty acyl-CoA reductase CG5065      

Location in the cell

PlasmaMembrane   Reliability : 2.36

CDS

ATGATCGCCCACGATTCTTATAAATCCATACCGGATTTCTATGCTGGAAAAACAGTCTTCATTACAGGAGGAACAGGATTCCTAGGGAAGGTCCTAGTCGAGAAGTTGGTATACAGCTGTCCCGCATTGAATAAAGTTTACGTATTGATACGAGAAACACCCAAGCAGAATGTTTTACAAAAATTAAAACAACTTCTTGATAGTCCGATTTTTACTCGACTAAAGAATGAAAGACCAGAAGATTTGAATAAAATTGTGCCTATTGCTGGAGACTTATGCAAACCGAACCTTGGTCTGGAGCCTAGTGATGAAGAAAAACTAATCGATGAGGTGTCGGTTGTAATTCATTCAGGTGCCACAGTCAAGTTTAACGATGCACTTGAATATGCAATGAAAATCAACTATCAAGGAACCGAACAGGTCATGCGTTTGTGTCGTAAGATAAAGAATATAAAGGTCTTTGTGTATATATCGACAACATATGCTCACACACAGTTAGATATTATAGAAGAGGTCATCTACCCTCCACCCGCAAGAGTAGCGGAAGTATACGAAACTATCAAACGACACGGAAACAACGAGAAGAATATCAGTAAAATACTCAATGGTCAACCAAACACATACGCTTTCACGAAAGCACTCGCCGAGAACCTTGTGGCTGAAAACCACGGCGACATTCCTACTGTAGTCATAAGACCTTCCATCATAACAGCTGGAATTACGGAGCCTCTTGAAGGATGGGTTGACACTTGGAATGGAGCCACAGGAATAATGCACTTGATCGGGAAAGGTTTATGCCGTGTGCTACCTGGCAACGAGCAGAACATACTGGATTTGATCCCAGTAGATTTTGTTTGTAATCTCGCATTAGTAGCTGCTGCTAAATGTAACAGTTCCAAAAAAGTAACAATTCTAAATAGCTGTTCTGGTTCCTGCAATCCAATTACATTAAAACAATTCTGTTCGCTGTACTGTAATGTCGCTGTAAAACGAAAGAGCAATGTTTTCCCATTTCCGTACCTTATATTATTCAACCCGCACATCTGGATGCTGAAGGTTATGAGCTATTTTCTAATGACTATGGCTGGACTCGCAGATTTCGTGATGCGAATCTTCGGCAAGCAGACAATGTTCTTCAGAACACAATCCAAGCTATACTCTATTGTGAAGACATTACGATGCTTCATATTTAAGTCGTGGGTGTTTAAATGCGAGCGAGTGTGCGCCCTTAATGCAGAGCTCAGTGACCTGGACCGCGCCGTCTTCAACTGCGACCCCTCCACAATACATTGGGAGCAATACGCACAAATATACTTCGATGGTGTCACGAAATTTTTACTGGAAAAACCGAAGAACCTAAGAACAGATGCGTCGAACAATTAA

Protein

MIAHDSYKSIPDFYAGKTVFITGGTGFLGKVLVEKLVYSCPALNKVYVLIRETPKQNVLQKLKQLLDSPIFTRLKNERPEDLNKIVPIAGDLCKPNLGLEPSDEEKLIDEVSVVIHSGATVKFNDALEYAMKINYQGTEQVMRLCRKIKNIKVFVYISTTYAHTQLDIIEEVIYPPPARVAEVYETIKRHGNNEKNISKILNGQPNTYAFTKALAENLVAENHGDIPTVVIRPSIITAGITEPLEGWVDTWNGATGIMHLIGKGLCRVLPGNEQNILDLIPVDFVCNLALVAAAKCNSSKKVTILNSCSGSCNPITLKQFCSLYCNVAVKRKSNVFPFPYLILFNPHIWMLKVMSYFLMTMAGLADFVMRIFGKQTMFFRTQSKLYSIVKTLRCFIFKSWVFKCERVCALNAELSDLDRAVFNCDPSTIHWEQYAQIYFDGVTKFLLEKPKNLRTDASNN

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Catalyzes the reduction of C16 or C18 fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Keywords

Complete proteome   Lipid biosynthesis   Lipid metabolism   Membrane   NADP   Oxidoreductase   Peroxisome   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Putative fatty acyl-CoA reductase CG5065

Uniprot

A0A194QNF1   A0A0P0IV71   A0A2A4J0C7   A0A1V0M878   A0A194PI13   A0A194PI08   + More
D2SNU9   I3PN84   I3PN86   A0A291P0K3   A0A0P0ES22   A0A090C638   I3PN85   A0A0P0I5I6   A0A291P0W0   A0A0F6Q4M2   A0A212EK35   A0A0F6NS86   A0A2A4JQ58   A0A1V0M875   W5QMH3   A0A0N7IQX9   A0A2H1VMP7   U5KFM8   A0A194QMY3   A0A068FL32   A0A068FRD8   Q7YTA9   Q7YTA8   A0A076FRK0   A0A212EK03   A0A2H1W6U5   W5QM70   D7P5E3   D7P5E5   D7P5E6   A0A2H1VWL8   A0A2A4JCF9   H9JLQ6   A0A2W1B441   A0A212F418   A0A1L8D6A3   A0A0N1IPU7   A0A0C9QJE0   A0A194PSL9   A0A2J7PM67   A0A194PP95   A0A291P0J5   A0A194QMY2   A0A067R949   A0A1B6JB63   A0A1B6GUZ4   E0VLJ7   A0A336LRW3   A0A336MZZ9   A0A1W4WEK2   A0A1B6KYT4   A0A195D193   A0A194PJP6   A0A310SYR9   A0A1I8PNE0   A0A1J1IBH8   A0A1I8M522   T1PAL6   A0A151WGN3   A0A0J7KV18   A0A195E2A0   A0A1L8DYU2   E9J0E5   A0A195ETJ3   A0A1B0CS61   A0A158NHJ4   A0A0L7QWX8   E2AKA1   A0A224XJF5   A0A026WZZ2   V5GSY3   E2B9J0   A0A0L0BVZ6   D2A660   A0A023F1V0   A0A069DV62   A0A0M8ZN21   B4KSN0   B4LPA3   B4JWM8   A0A0P5QJM8   A0A3Q8FTW8   A0A0K8U8F7   A0A034VN48   A0A0M4EVU9   A0A0A1WIW0   A0A2A3EL05   V9IAG7   W8AXT4   E1JH83   A1ZAI5   A0A0A9WTX4   A0A1A9X2G9  

EC Number

1.2.1.84

Pubmed

26354079    27427355    28349297    20074338    22615947    28986331    + More
26445454    25558806    22118469    24862548    24053512    26385554    12871998    24817326    20534481    19121390    28756777    24845553    20566863    25315136    21282665    21347285    20798317    24508170    30249741    26108605    18362917    19820115    25474469    26334808    17994087    25348373    25830018    24495485    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25401762    26823975   

EMBL

KQ461194    KPJ06884.1    KR781121    ALJ94061.1    NWSH01004349    PCG65196.1    + More
KU755478    ARD71188.1    KQ459603    KPI92957.1    KPI92952.1    EZ407233    ACX53790.1    JF709976    AFD04726.1    JF709978    AFD04728.1    MF687545    ATJ44471.1    KT261697    ALJ30237.1    HG423128    CDG50833.1    JF709977    KP237931    AFD04727.1    AKD01784.1    KR781120    ALJ94060.1    MF687590    ATJ44516.1    KP237920    AKD01773.1    AGBW02014338    OWR41841.1    KF805977    AIS85928.1    NWSH01000832    PCG73949.1    KU755477    ARD71187.1    JQ978770    AGD98718.1    KR781119    ALJ94059.1    ODYU01003396    SOQ42100.1    JX989164    AGR49323.1    KPJ06882.1    JX679210    KJ622060    AGP26039.1    AID66648.1    KJ622067    AID66655.1    AB104896    BAC79425.1    AB104897    BAC79426.1    KF960748    AII21950.1    OWR41842.1    ODYU01006707    SOQ48800.1    JQ978771    AGD98719.1    GQ907232    ADD62439.1    GQ907234    ADD62441.1    GQ907235    ADD62442.1    ODYU01004894    SOQ45237.1    NWSH01002009    PCG69446.1    BABH01005237    KZ150367    PZC71169.1    AGBW02010466    OWR48453.1    GEYN01000140    JAV01989.1    KQ460036    KPJ18402.1    GBYB01014923    GBYB01014924    JAG84690.1    JAG84691.1    KQ459593    KPI96431.1    NEVH01024421    PNF17417.1    KPI92955.1    MF687541    ATJ44467.1    KPJ06883.1    KK852807    KDR16086.1    GECU01011206    JAS96500.1    GECZ01003528    JAS66241.1    DS235271    EEB14253.1    UFQT01000095    SSX19701.1    UFQT01004920    SSX35816.1    GEBQ01023412    JAT16565.1    KQ976973    KYN06637.1    KPI92954.1    KQ759773    OAD62927.1    CVRI01000047    CRK97592.1    KA645200    AFP59829.1    KQ983167    KYQ46967.1    LBMM01002956    KMQ94136.1    KQ979763    KYN19268.1    GFDF01002480    JAV11604.1    GL767462    EFZ13704.1    KQ981975    KYN31575.1    AJWK01025651    AJWK01025652    ADTU01015858    KQ414706    KOC63100.1    GL440209    EFN66142.1    GFTR01006468    JAW09958.1    KK107069    QOIP01000002    EZA60709.1    RLU26126.1    GALX01005113    JAB63353.1    GL446556    EFN87623.1    JRES01001254    KNC24212.1    KQ971346    EFA04974.1    GBBI01003721    JAC14991.1    GBGD01001183    JAC87706.1    KQ436010    KOX67575.1    CH933808    EDW10529.2    CH940648    EDW60212.2    CH916375    EDV98366.1    GDIQ01123144    JAL28582.1    MG573164    AWJ25026.1    GDHF01029367    GDHF01008158    JAI22947.1    JAI44156.1    GAKP01015960    GAKP01015959    GAKP01015958    GAKP01015956    JAC42993.1    CP012524    ALC42075.1    GBXI01017222    GBXI01017048    GBXI01015288    GBXI01014990    GBXI01003875    JAC97069.1    JAC97243.1    JAC99003.1    JAC99301.1    JAD10417.1    KZ288220    PBC32174.1    JR038077    JR038078    AEY58108.1    AEY58109.1    GAMC01012755    JAB93800.1    AE013599    ACZ94440.1    AAF57974.1    GBHO01033661    GBHO01033660    GBRD01008049    GBRD01008048    GBRD01008047    GDHC01019056    GDHC01002516    JAG09943.1    JAG09944.1    JAG57772.1    JAP99572.1    JAQ16113.1   

Proteomes

UP000053240    UP000218220    UP000053268    UP000007151    UP000005204    UP000235965    + More
UP000027135    UP000009046    UP000192223    UP000078542    UP000095300    UP000183832    UP000095301    UP000075809    UP000036403    UP000078492    UP000078541    UP000092461    UP000005205    UP000053825    UP000000311    UP000053097    UP000279307    UP000008237    UP000037069    UP000007266    UP000053105    UP000009192    UP000008792    UP000001070    UP000092553    UP000242457    UP000000803    UP000091820   

PRIDE

Q7YTA9    Q7YTA8    H9JLQ6    A1ZAI5   

Pfam

PF07993   NAD_binding_4        + More
PF03015   Sterile

Interpro

IPR033640   FAR_C        + More
IPR013120   Male_sterile_NAD-bd       
IPR036291   NAD(P)-bd_dom_sf       
IPR026055   FAR       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

A0A194QNF1   A0A0P0IV71   A0A2A4J0C7   A0A1V0M878   A0A194PI13   A0A194PI08   + More
D2SNU9   I3PN84   I3PN86   A0A291P0K3   A0A0P0ES22   A0A090C638   I3PN85   A0A0P0I5I6   A0A291P0W0   A0A0F6Q4M2   A0A212EK35   A0A0F6NS86   A0A2A4JQ58   A0A1V0M875   W5QMH3   A0A0N7IQX9   A0A2H1VMP7   U5KFM8   A0A194QMY3   A0A068FL32   A0A068FRD8   Q7YTA9   Q7YTA8   A0A076FRK0   A0A212EK03   A0A2H1W6U5   W5QM70   D7P5E3   D7P5E5   D7P5E6   A0A2H1VWL8   A0A2A4JCF9   H9JLQ6   A0A2W1B441   A0A212F418   A0A1L8D6A3   A0A0N1IPU7   A0A0C9QJE0   A0A194PSL9   A0A2J7PM67   A0A194PP95   A0A291P0J5   A0A194QMY2   A0A067R949   A0A1B6JB63   A0A1B6GUZ4   E0VLJ7   A0A336LRW3   A0A336MZZ9   A0A1W4WEK2   A0A1B6KYT4   A0A195D193   A0A194PJP6   A0A310SYR9   A0A1I8PNE0   A0A1J1IBH8   A0A1I8M522   T1PAL6   A0A151WGN3   A0A0J7KV18   A0A195E2A0   A0A1L8DYU2   E9J0E5   A0A195ETJ3   A0A1B0CS61   A0A158NHJ4   A0A0L7QWX8   E2AKA1   A0A224XJF5   A0A026WZZ2   V5GSY3   E2B9J0   A0A0L0BVZ6   D2A660   A0A023F1V0   A0A069DV62   A0A0M8ZN21   B4KSN0   B4LPA3   B4JWM8   A0A0P5QJM8   A0A3Q8FTW8   A0A0K8U8F7   A0A034VN48   A0A0M4EVU9   A0A0A1WIW0   A0A2A3EL05   V9IAG7   W8AXT4   E1JH83   A1ZAI5   A0A0A9WTX4   A0A1A9X2G9  

PDB

4W4T     E-value=2.04744e-16,     Score=210

KEGG

101745831    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) putative fatty acyl-CoA red

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0080019   GO:0102965   GO:0006629   GO:0016021   GO:0005783   GO:0005777   GO:0035336   GO:0010025   GO:0005778   GO:0008611   GO:0005779  

PANTHER

PTHR11011  

Subcellular location

Peroxisome membrane  

Length:

460

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

21.84033

Exp number, first 60 AAs:

1.55017

Total prob of N-in:

0.12982

outside

1  -  345

TMhelix

346  -  368

inside

369  -  460

 

 

Pi

178.821625

Theta

154.201029

Tajima's D

0.922422

CLR

0.1977

CSRT

0.63586820658967

Interpretation

Uncertain