Gene

KWMTBOMO07031

Pre Gene Modal

BGIBMGA010458

Annotation

fatty-acyl_reductase_[Bombyx_mori]

Location

Bomo_Chr12(-):2180688-2192879      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

PlasmaMembrane   Reliability : 1.771

CDS

ATGTCACACAATGGAACTTTGGATGAACATTATCAGACCGTGAGGGAATTTTACGATGGTAAATCCGTTTTTATTACAGGAGCGACCGGATTCCTTGGAAAGGCGTACGTTGAGAAACTTGCGTATTCGTGTCCGGGCATAGTAAGCATTTACATTTTGATTCGAGACAAGAAAGGGTCGAACACTGAAGAGCGAATGAGAAAATATCTTGATCAGCCCATTTTTTCACGAATAAAATACGAACATCCAGAATATTTCAAAAAAATCATTCCCATCTCTGGTGATATCACCGCACCCAAACTAGGATTGTGCGATGAAGAAAGAAATATATTAATCAACGAGGTGTCGATAGTGATTCACTCAGCCGCTTCGGTCAAACTAAACGATCATTTAAAATTTACTCTGAACACGAATGTTGGAGGTACGATGAAAGTGTTGGAACTCGTTAAAGAAATGAAAAACTTAGCGATGTTCGTATATGTGTCTACAGCTTATTCTAACACAAGTCAAAGAATTTTAGAAGAAAAACTTTATCCTCAGTCCCTAAATCTAAACGAAATACAGAAGTTCGCTGAAGAACATTATATATTAGGTAAAGACAACGATGAAATGATAAAATTTATAGGTAACCACCCAAACACATATGCATACACAAAAGCGCTGGCAGAAAACTTAGTTGCTGAAGAACACGGTGAAATACCAACAATTATCATTAGGCCTTCGATTATTACAGCGAGTGCTGAAGAGCCAGTGCGAGGGTTCGTGGATAGTTGGAGTGGTGCAACTGCTATGGCAGCATTTGCTTTGAAGGGATGGAACAACATAATGTACAGCACAGGCGAGGAGAATATTGATCTGATACCTCTAGACTATGTTGTCAACCTTACATTAGTAGCGATTGCTAAATATAAGCCTACCAAAGAGGTCACAGTATATCACGTCACAACCAGCGATCTTAATCCCATTTCAATCCGAAGAATATTTATAAAGCTCTCCGAATTCGCATCAAAAAATCCAACGAGTAATGCCGCACCATTCGCAGCAACGACTTTATTGACTAAACAGAAGCCATTAATAAAACTGGTCACGTTTCTCATGCAGACGACGCCGGCTTTCCTAGCTGACTTATGGATGAAAACCCAGAGGAAAGAAGCCAAATTCGTCAAGCAACATAATCTAGTAGTGAGAAGTCGTGATCAACTGGAATTCTTCACGTCTCAGTCGTGGTTGCTTCGTTGCGAGCGAGCCCGTGTGCTTAGTGCGGCACTGAGCGATTCAGACCGCGCTGTCTTCCGCTGCGATCCTTCCACCATAGACTGGGACCAATATTTGCCAATATACTTCGAAGGAATCAACAAGCATCTGTTCAAAAATAAATTATAG

Protein

MSHNGTLDEHYQTVREFYDGKSVFITGATGFLGKAYVEKLAYSCPGIVSIYILIRDKKGSNTEERMRKYLDQPIFSRIKYEHPEYFKKIIPISGDITAPKLGLCDEERNILINEVSIVIHSAASVKLNDHLKFTLNTNVGGTMKVLELVKEMKNLAMFVYVSTAYSNTSQRILEEKLYPQSLNLNEIQKFAEEHYILGKDNDEMIKFIGNHPNTYAYTKALAENLVAEEHGEIPTIIIRPSIITASAEEPVRGFVDSWSGATAMAAFALKGWNNIMYSTGEENIDLIPLDYVVNLTLVAIAKYKPTKEVTVYHVTTSDLNPISIRRIFIKLSEFASKNPTSNAAPFAATTLLTKQKPLIKLVTFLMQTTPAFLADLWMKTQRKEAKFVKQHNLVVRSRDQLEFFTSQSWLLRCERARVLSAALSDSDRAVFRCDPSTIDWDQYLPIYFEGINKHLFKNKL

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Uniprot

Q7YTA9   Q7YTA8   H9JLQ6   W5QMH3   A0A194PI13   W5QM70   + More
A0A212EK35   A0A2A4J0C7   A0A194QMY3   A0A291P0K3   A0A291P0W0   I3PN84   I3PN85   A0A2H1VMP7   A0A2H1W6U5   D2SNU9   I3PN86   A0A0N7IQX9   A0A0F6Q4M2   A0A0P0IV71   A0A194QNF1   A0A076FRK0   A0A068FL32   A0A1V0M878   A0A068FRD8   A0A0P0ES22   A0A090C638   A0A2A4JQ58   A0A0P0I5I6   A0A194PI08   A0A0F6NS86   A0A1V0M875   U5KFM8   A0A212EK03   A0A2H1VWL8   A0A2W1B441   D7P5E3   D7P5E6   D7P5E5   E0VLJ7   D2A660   A0A0T6BDN9   A0A2A3EL05   V9IAG7   A0A0N1IPU7   D9MWM7   A0A194PSL9   K7J1Z7   E9J0E5   A0A2A4JCF9   A0A195ETJ3   A0A195E2A0   A0A0M8ZN21   A0A195D193   A0A158NHJ4   A0A310SYR9   A0A151WGN3   A0A291P0J5   A0A067R949   A0A212F418   E2AKA1   A0A026WZZ2   A0A336LRW3   A0A0J7KV18   A0A336MZZ9   A0A0L7QWX8   A0A1D2MIG9   A0A0C9QJE0   V5GSY3   E2B9J0   A0A2J7PM67   A0A067QNH3   Q172Q7   A0A1W4WEK2   A0A069DV62   A0A1B6JB63   Q172Q8   A0A224XJF5   E2AKQ3   A0A1J1IBH8   A0A023ETM2   A0A226E5U8   A0A1B6GUZ4   V9KGP9   A0A1L8DYU2   A0A0K8U8F7   A0A034VN48   E2BHA7   F4W5T8   A0A1B6KYT4   A0A210QI00   A0A195DFI7   E9HD03   W8AXT4   A0A1B0CS61   A0A0L0BVZ6   A0A2J7PLY4   Q9I989   T1E2J9  

EC Number

1.2.1.84

Pubmed

12871998    19121390    24862548    26354079    22118469    28986331    + More
22615947    20074338    27427355    24817326    26385554    28349297    26445454    25558806    24053512    28756777    20534481    20566863    18362917    19820115    20542116    20075255    21282665    21347285    24845553    20798317    24508170    30249741    27289101    17510324    26334808    24945155    24402279    25348373    21719571    28812685    21292972    24495485    26108605    24330624   

EMBL

AB104896    BAC79425.1    AB104897    BAC79426.1    BABH01005237    JQ978770    + More
AGD98718.1    KQ459603    KPI92957.1    JQ978771    AGD98719.1    AGBW02014338    OWR41841.1    NWSH01004349    PCG65196.1    KQ461194    KPJ06882.1    MF687545    ATJ44471.1    MF687590    ATJ44516.1    JF709976    AFD04726.1    JF709977    KP237931    AFD04727.1    AKD01784.1    ODYU01003396    SOQ42100.1    ODYU01006707    SOQ48800.1    EZ407233    ACX53790.1    JF709978    AFD04728.1    KR781119    ALJ94059.1    KP237920    AKD01773.1    KR781121    ALJ94061.1    KPJ06884.1    KF960748    AII21950.1    JX679210    KJ622060    AGP26039.1    AID66648.1    KU755478    ARD71188.1    KJ622067    AID66655.1    KT261697    ALJ30237.1    HG423128    CDG50833.1    NWSH01000832    PCG73949.1    KR781120    ALJ94060.1    KPI92952.1    KF805977    AIS85928.1    KU755477    ARD71187.1    JX989164    AGR49323.1    OWR41842.1    ODYU01004894    SOQ45237.1    KZ150367    PZC71169.1    GQ907232    ADD62439.1    GQ907235    ADD62442.1    GQ907234    ADD62441.1    DS235271    EEB14253.1    KQ971346    EFA04974.1    LJIG01001484    KRT85456.1    KZ288220    PBC32174.1    JR038077    JR038078    AEY58108.1    AEY58109.1    KQ460036    KPJ18402.1    HM483391    ADJ56408.1    KQ459593    KPI96431.1    GL767462    EFZ13704.1    NWSH01002009    PCG69446.1    KQ981975    KYN31575.1    KQ979763    KYN19268.1    KQ436010    KOX67575.1    KQ976973    KYN06637.1    ADTU01015858    KQ759773    OAD62927.1    KQ983167    KYQ46967.1    MF687541    ATJ44467.1    KK852807    KDR16086.1    AGBW02010466    OWR48453.1    GL440209    EFN66142.1    KK107069    QOIP01000002    EZA60709.1    RLU26126.1    UFQT01000095    SSX19701.1    LBMM01002956    KMQ94136.1    UFQT01004920    SSX35816.1    KQ414706    KOC63100.1    LJIJ01001147    ODM92798.1    GBYB01014923    GBYB01014924    JAG84690.1    JAG84691.1    GALX01005113    JAB63353.1    GL446556    EFN87623.1    NEVH01024421    PNF17417.1    KK853123    KDR11037.1    CH477432    EAT41040.1    GBGD01001183    JAC87706.1    GECU01011206    JAS96500.1    EAT41039.1    GFTR01006468    JAW09958.1    GL440368    EFN65993.1    CVRI01000047    CRK97592.1    GAPW01000903    JAC12695.1    LNIX01000006    OXA53032.1    GECZ01003528    JAS66241.1    JW864586    AFO97103.1    GFDF01002480    JAV11604.1    GDHF01029367    GDHF01008158    JAI22947.1    JAI44156.1    GAKP01015960    GAKP01015959    GAKP01015958    GAKP01015956    JAC42993.1    GL448287    EFN84876.1    GL887695    EGI70414.1    GEBQ01023412    JAT16565.1    NEDP02003577    OWF48372.1    KQ980903    KYN11612.1    GL732622    EFX70381.1    GAMC01012755    JAB93800.1    AJWK01025651    AJWK01025652    JRES01001254    KNC24212.1    PNF17348.1    AJ272073    CAB75890.1    GALA01001195    JAA93657.1   

Proteomes

UP000005204    UP000053268    UP000007151    UP000218220    UP000053240    UP000009046    + More
UP000007266    UP000242457    UP000005203    UP000002358    UP000078541    UP000078492    UP000053105    UP000078542    UP000005205    UP000075809    UP000027135    UP000000311    UP000053097    UP000279307    UP000036403    UP000053825    UP000094527    UP000008237    UP000235965    UP000008820    UP000192223    UP000183832    UP000198287    UP000007755    UP000242188    UP000000305    UP000092461    UP000037069   

PRIDE

Q7YTA9    Q7YTA8    H9JLQ6   

Pfam

PF03015   Sterile        + More
PF07993   NAD_binding_4

Interpro

IPR036291   NAD(P)-bd_dom_sf        + More
IPR013120   Male_sterile_NAD-bd       
IPR033640   FAR_C       
IPR026055   FAR       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

Q7YTA9   Q7YTA8   H9JLQ6   W5QMH3   A0A194PI13   W5QM70   + More
A0A212EK35   A0A2A4J0C7   A0A194QMY3   A0A291P0K3   A0A291P0W0   I3PN84   I3PN85   A0A2H1VMP7   A0A2H1W6U5   D2SNU9   I3PN86   A0A0N7IQX9   A0A0F6Q4M2   A0A0P0IV71   A0A194QNF1   A0A076FRK0   A0A068FL32   A0A1V0M878   A0A068FRD8   A0A0P0ES22   A0A090C638   A0A2A4JQ58   A0A0P0I5I6   A0A194PI08   A0A0F6NS86   A0A1V0M875   U5KFM8   A0A212EK03   A0A2H1VWL8   A0A2W1B441   D7P5E3   D7P5E6   D7P5E5   E0VLJ7   D2A660   A0A0T6BDN9   A0A2A3EL05   V9IAG7   A0A0N1IPU7   D9MWM7   A0A194PSL9   K7J1Z7   E9J0E5   A0A2A4JCF9   A0A195ETJ3   A0A195E2A0   A0A0M8ZN21   A0A195D193   A0A158NHJ4   A0A310SYR9   A0A151WGN3   A0A291P0J5   A0A067R949   A0A212F418   E2AKA1   A0A026WZZ2   A0A336LRW3   A0A0J7KV18   A0A336MZZ9   A0A0L7QWX8   A0A1D2MIG9   A0A0C9QJE0   V5GSY3   E2B9J0   A0A2J7PM67   A0A067QNH3   Q172Q7   A0A1W4WEK2   A0A069DV62   A0A1B6JB63   Q172Q8   A0A224XJF5   E2AKQ3   A0A1J1IBH8   A0A023ETM2   A0A226E5U8   A0A1B6GUZ4   V9KGP9   A0A1L8DYU2   A0A0K8U8F7   A0A034VN48   E2BHA7   F4W5T8   A0A1B6KYT4   A0A210QI00   A0A195DFI7   E9HD03   W8AXT4   A0A1B0CS61   A0A0L0BVZ6   A0A2J7PLY4   Q9I989   T1E2J9  

PDB

4W4T     E-value=5.63059e-09,     Score=146

KEGG

692514    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) Far; fatty-acyl reductase

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0080019   GO:0102965   GO:0006629   GO:0016021   GO:0005783   GO:0005777   GO:0035336   GO:0010025  

PANTHER

PTHR11011  

Length:

460

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.25569

Exp number, first 60 AAs:

0.14689

Total prob of N-in:

0.00933

outside

1  -  460

 

 

Pi

203.826251

Theta

191.388657

Tajima's D

0.342347

CLR

0.000072

CSRT

0.461076946152692

Interpretation

Uncertain