Gene

KWMTBOMO07012  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010505

Annotation

carboxylesterase_precursor_[Bombyx_mori]

Location

Bomo_Chr12(+):1828494-1831054      View in EpiBrowser

Full name

Carboxylic ester hydrolase      

Location in the cell

Cytoplasmic   Reliability : 2.905

CDS

ATGTGGCGTACGTTGTTGTTCGGTGCTTTTATTCTTGGTCAAACGAAGACCGAAGACGCGATTGACGAGTGGAAGGAAGTCCTCCTAGACCAGGGCCCGGTACGAGGCTACAAGGATCCTGAAGTCGACGTGTTCGTGTTTCATGGGATCCCTTATGCTAGTGCACCAAAGGGACCTGACAAGTTCAAGGCTCCTCTTCCTCCGCCAACATGGAAGGAACCTTTCGAAGCAGTAGACAAAGGAGTCATGTGTCCCCAACATCCTGTCGACATGGGCTTTAAAAAGAAATTCATCTACAATGAAGATTGCCTCATCGCAAATGTGTTTGTACCAGACGCCGACAATAAAAATCTTCCTGTCGTTGTATATGTCCACGGTGGTGGATACCAAGTCGGCTTCGGTAACAGCGTAACACCAAAAAAATTAGTTAGGGGTGAAAAAATTATAGCAATAACCTTTAACTACCGCTTAGGTGCGCATGGTTTTCTATGTCTGGGCACAAAAGAGGCTCCGGGTAATGCAGGCATGAAAGATATAGTTGCCCTCCTCAGGTGGGTGAAGAAAAACATCGAAAAATTTGGTGGAAACCCTGAAGAAGTCACAATCGCTGGATATAGCTCGGGAGCTGCTGCAGTTGAACTTCTAATGCTCTCCGACCTAACTAGAGGGTTATTTAACAAAGCTATACCCGAAAGCGGATCGGCTCTAGCATCTTTCACGATACAACGAGATCCATTGGCTAATGCTAAGAAGTTTGCCAAAAAGATGAACGTAACAGATGTAGATGACATTGAGGTTTTAGAAAAGTTTTATACGAAAGCTTCTTTCAAGAAACTAACCGCTAATACATTTTCCGGTGCCCCCGGTACGGCAATCAGTTTTGAGCCTTGCATTGAACGAGACATAGGTGAGGAAGCATTTCTAACAGAAGCTCCAGTAAACATTATAAGTAAAGGAAAATACCAGAAGGTACCAATTCTCTTTGGCATCTGCAACATGGAAGGTTTAGTTCGAGTGAACTATTTCGAAATGTGGTTGGAGAAATTCAACTCGAAATTCTCACAGTACTTGCCATCAAATTTGAAATTCGAAAGCCAAGAACAAAAGGAAGAAATCGCGAAAAAGGTCAAAGAATTTTATTTCGGCAAAAAAACTATCACTGAATCGAATATTTTGGCTTACATTGACTACTTCACTGATGTTATGTTTGCTTTTCCCGTATTGAGATCTGTCAAGATGCATTTAGAAGCTGGGCATGATCGAATATATTTATATGAGTACAGTTTCGTAGATGAAGACACAATGCCAATTCCGTACGTAGATGTTAAAGGTGCCGATCATATTGCACAGACAAATGCTGTATTAGACGGCTTGAACGCGACACATTACGACGAAAGCATGGCATCGAAAACTTATAAAAGAATGAAAGCTAGAATGCGAGAAATGTGGACAAATTTCATAGTTACCGGTAAACCGGTGCCTGAAGACTCAATACTCCCAAAATGGCCACCAGTCGAGAAGGATTGGTCTCCTCATATGTCCATAGGAGAAGTAATTGAGCTAAGAGGTTCACTACTCGAAAAACGCGCCAAATTATGGGACGAAATTTACCAACAGTTCTATTATAATCCAATACCACCCGCTACATTAGAAACGAAACATACTGAATTGTAG

Protein

MWRTLLFGAFILGQTKTEDAIDEWKEVLLDQGPVRGYKDPEVDVFVFHGIPYASAPKGPDKFKAPLPPPTWKEPFEAVDKGVMCPQHPVDMGFKKKFIYNEDCLIANVFVPDADNKNLPVVVYVHGGGYQVGFGNSVTPKKLVRGEKIIAITFNYRLGAHGFLCLGTKEAPGNAGMKDIVALLRWVKKNIEKFGGNPEEVTIAGYSSGAAAVELLMLSDLTRGLFNKAIPESGSALASFTIQRDPLANAKKFAKKMNVTDVDDIEVLEKFYTKASFKKLTANTFSGAPGTAISFEPCIERDIGEEAFLTEAPVNIISKGKYQKVPILFGICNMEGLVRVNYFEMWLEKFNSKFSQYLPSNLKFESQEQKEEIAKKVKEFYFGKKTITESNILAYIDYFTDVMFAFPVLRSVKMHLEAGHDRIYLYEYSFVDEDTMPIPYVDVKGADHIAQTNAVLDGLNATHYDESMASKTYKRMKARMREMWTNFIVTGKPVPEDSILPKWPPVEKDWSPHMSIGEVIELRGSLLEKRAKLWDEIYQQFYYNPIPPATLETKHTEL

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Feature

chain  Carboxylic ester hydrolase

Uniprot

H9JLV3   Q4TTE1   A0A2H1V567   A0A2A4J481   M9WMP0   A0A2A4J4E2   + More
D5G3C9   S4WMC9   A0A2A4J4F1   A0A2H1WVG2   A0A0U3BZB1   D9IV62   D5KXB3   A0A2A4J333   D5G3D1   A0A2H1V6U9   D5KXB6   D5KXB2   D9IV61   A0A140IEY4   D5KXB7   D5KXB8   D3GDL5   A0A291P0Y8   A0A2A4J321   D5G3D0   D5KXB9   D5KXC0   D5KXB4   A0A2A4J554   D5KX87   D5KXB5   D5KX89   D5KX88   G1C2I4   D5KX84   D5KX92   D5KX86   H9ZVH4   D5KX90   H9JDF0   D5KX82   A0A2A4J489   D5KX83   D3GDM5   D5KXC1   D5KX91   D5KX85   A0A2A4J3V0   D5G3C6   D5KX93   A0A2H1V569   A0A2H1V6G1   A0A2U3T8K8   A0A2U3T8K2   A0A076FRL8   A0A2A4J4Y7   A0A2A4J4U9   G0T5Q2   A0A127KQ69   D5G3D4   H9JDE9   S4WFZ6   A0A0K8TVB0   A0A1U9X1U8   A0A0C5BXH0   A0A2H1WXB4   A0A0K8TUN3   A0A2H1V558   A0A0H4SJY1   A0A0L7L5N8   A0A0K0XRT8   D5G3D3   D5G3D5   A0A2H1V574   D3GDL8   A0A0K8TV97   A0A127KQ42   A0A1U9X1S9   A0A0K8TUP4   A0A291P0R4   D5KXA1   A0A194PQT2   D5KXA2   D5KX99   D5KXA3   A0A2A4J3H7   A0A2H1V316   A0A0C5C1L6   D5KXA4   M9WLF7   A0A2H1V568   A0A0K8TV81   D5G3D8   A0A2A4J3L3   A0A2H1V4P3   D5KXB0   G3CM72   D5KX98   D5KXA8  

EC Number

3.1.1.-

Pubmed

19121390    24753123    20005949    23799064    20875855    28986331    + More
24817326    26017144    26227816    26198868    26354079   

EMBL

BABH01005196    BABH01005197    BABH01005198    DQ073457    AAY54259.1    ODYU01000738    + More
SOQ35981.1    NWSH01003330    PCG66536.1    KC493657    AGJ94046.1    PCG66538.1    FJ997293    ADF43458.1    KC589105    AGO98723.1    PCG66548.1    ODYU01011357    SOQ57053.1    KT345935    ALT14583.1    HM191472    MF687569    ADJ96632.1    ATJ44495.1    GU647138    ADE05551.1    PCG66547.1    FJ997295    ADF43460.1    SOQ35984.1    GU647141    ADE05554.1    GU647137    ADE05550.1    HM191471    ADJ96631.1    KT345936    AMO44416.1    GU647142    ADE05555.1    GU647143    ADE05556.1    FJ652447    ACV60231.1    MF687620    ATJ44546.1    PCG66537.1    FJ997294    ADF43459.1    GU647144    ADE05557.1    GU647145    ADE05558.1    GU647139    ADE05552.1    PCG66543.1    GU647112    ADD97154.1    GU647140    ADE05553.1    GU647114    ADD97156.1    GU647113    ADD97155.1    JF728803    AEJ38205.1    GU647109    ADD97151.1    GU647117    ADD97159.1    GU647111    ADD97153.1    JQ684436    AFH40334.1    GU647115    ADD97157.1    BABH01030065    GU647107    ADD97149.1    PCG66546.1    GU647108    ADD97150.1    FJ652457    ACV60241.1    GU647146    ADE05559.1    GU647116    ADD97158.1    GU647110    ADD97152.1    PCG66539.1    FJ997290    ADF43455.1    GU647118    ADD97160.1    SOQ35983.1    SOQ35982.1    KX015863    ARM65392.1    KX015854    ARM65383.1    KF960786    AII21988.1    NWSH01003365    PCG66462.1    PCG66460.1    GU119888    ADK62515.1    KT345938    AMO44418.1    FJ997298    ADF43463.1    BABH01030066    KC589104    AGO98722.1    GCVX01000029    JAI18201.1    KY021846    AQY62735.1    KP001153    AJN91198.1    SOQ57054.1    GCVX01000038    JAI18192.1    SOQ35980.1    KP677291    AKP92859.1    JTDY01002769    KOB70767.1    KP938889    AKS40370.1    FJ997297    ADF43462.1    FJ997299    ADF43464.1    SOQ35978.1    FJ652450    ACV60234.1    GCVX01000022    JAI18208.1    KT345937    AMO44417.1    KY021822    AQY62711.1    GCVX01000028    JAI18202.1    MF687556    ATJ44482.1    GU647126    ADD97141.1    KQ459602    KPI93490.1    GU647127    ADD97142.1    GU647124    GU647125    ADD97139.1    GU647128    ADD97143.1    PCG66541.1    ODYU01000447    SOQ35235.1    KP001156    AJN91201.1    GU647129    GU647130    GU647131    ADD97144.1    ADD97145.1    KC493658    AGJ94047.1    SOQ35977.1    GCVX01000037    JAI18193.1    FJ997302    ADF43467.1    PCG66459.1    SOQ35234.1    GU647135    ADE05548.1    HQ122618    AEL33701.1    GU647123    ADD97138.1    GU647133    ADD97148.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053268   

PRIDE

H9JLV3    Q4TTE1    H9JDF0    H9JDE9   

Pfam

PF00135   COesterase        + More
PF00069   Pkinase

Interpro

IPR000719   Prot_kinase_dom        + More
IPR011009   Kinase-like_dom_sf       
IPR029058   AB_hydrolase       
IPR002018   CarbesteraseB       
IPR019826   Carboxylesterase_B_AS       

SUPFAM

SSF56112   SSF56112        + More
SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

H9JLV3   Q4TTE1   A0A2H1V567   A0A2A4J481   M9WMP0   A0A2A4J4E2   + More
D5G3C9   S4WMC9   A0A2A4J4F1   A0A2H1WVG2   A0A0U3BZB1   D9IV62   D5KXB3   A0A2A4J333   D5G3D1   A0A2H1V6U9   D5KXB6   D5KXB2   D9IV61   A0A140IEY4   D5KXB7   D5KXB8   D3GDL5   A0A291P0Y8   A0A2A4J321   D5G3D0   D5KXB9   D5KXC0   D5KXB4   A0A2A4J554   D5KX87   D5KXB5   D5KX89   D5KX88   G1C2I4   D5KX84   D5KX92   D5KX86   H9ZVH4   D5KX90   H9JDF0   D5KX82   A0A2A4J489   D5KX83   D3GDM5   D5KXC1   D5KX91   D5KX85   A0A2A4J3V0   D5G3C6   D5KX93   A0A2H1V569   A0A2H1V6G1   A0A2U3T8K8   A0A2U3T8K2   A0A076FRL8   A0A2A4J4Y7   A0A2A4J4U9   G0T5Q2   A0A127KQ69   D5G3D4   H9JDE9   S4WFZ6   A0A0K8TVB0   A0A1U9X1U8   A0A0C5BXH0   A0A2H1WXB4   A0A0K8TUN3   A0A2H1V558   A0A0H4SJY1   A0A0L7L5N8   A0A0K0XRT8   D5G3D3   D5G3D5   A0A2H1V574   D3GDL8   A0A0K8TV97   A0A127KQ42   A0A1U9X1S9   A0A0K8TUP4   A0A291P0R4   D5KXA1   A0A194PQT2   D5KXA2   D5KX99   D5KXA3   A0A2A4J3H7   A0A2H1V316   A0A0C5C1L6   D5KXA4   M9WLF7   A0A2H1V568   A0A0K8TV81   D5G3D8   A0A2A4J3L3   A0A2H1V4P3   D5KXB0   G3CM72   D5KX98   D5KXA8  

PDB

2FJ0     E-value=2.13987e-46,     Score=470

KEGG

692770    no KO assigned | (RefSeq) carboxylesterase

GO

GO:0004672   GO:0016787   GO:0005524   GO:0080030  

SignalP

Position:   1 - 17,         Likelihood:  0.902917

 

 

Length:

557

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06215

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00049

outside

1  -  557

 

 

Pi

226.390756

Theta

195.444664

Tajima's D

0.788295

CLR

0

CSRT

0.594170291485426

Interpretation

Uncertain