Gene

KWMTBOMO06996  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010477

Annotation

scavenger_receptor_class_B_member_4_[Bombyx_mori]

Location

Bomo_Chr12(-):1383173-1413749      View in EpiBrowser

Location in the cell

Lysosomal   Reliability : 1.328 PlasmaMembrane   Reliability : 1.872

CDS

ATGGTTCTACCTACGATGCGTGGTGGTTTGTTGAGATGGCGCTCGTTGTGGATCTGCGGAGGAGCGCTCTTAGCGCTTTCCGCGTTCGTCGCGGCCCTGACGTGGGGCGCGATCTTCGATTCAGCCTTCGGTTCTCAACTGGCGCTGATACCTGACTCTAGGTCGTTCATGAGGTGGCTAGAACCGGACGTGCCCATATTCTTCGATATATACATGTTCAACTGGACCAACCCTGAGCGATTCCCGGAGGAAAAACCAAATTTTGAAGAAATAGGTCCTTACCGTTACCAGGAGCATAGACGTCACGTGAATATCTCGTGGCACCCAGAGAACGGCACGATTGGGTACAGGACGCTTCGCAGCTGGGTGTGGGACGAGTCCAGCGTTGGGTCACAAGACGACATTATCACAACCATTGACGTTATAACCGCTTCAGCGATTTACCAGGCGAGGTTCAGTGGATTTATCGAACAGAAGCTCGTGTCTTTGACCCTGACGAGCTCGCAGCACACGAAGGTGTCCGTAACGGCGAGAGCCAGTGAGTTCCTCTTCGAAGGCTACGAGGACCCGCTCTTGAACCTGGCCAAGCTGATGCCAGCCAGTGTTAGAGGAGGTGCACCAGCTCTGGATCGATTCGGCTGGTTCTTCTCTAGGAACAACACGGATACTGACGGCTACATGGAAGTGACTTCGGGGACCCGGGACGGACTTCCCGGCCAGATCTTGAGATGGAACTATCAGGATCACATACCGTTTTACGACGGCGAATGCTCCAAGTTATCAGGAAGCGCTGGCGAGTATATCCCGAGGAACCTGACTGAGGACTCGAAGCTGACGATGTACGTGCCCGATCTCTGCAGAACCGTTAACATGGAGTTTGTGGAGAGTGGGGTTCAAAACGGACTGAAATACAACAAATATGAAGTCAACGAGAGAAGCTTTGATAACTCGTCGACGTCGCCGGAGAACACGTGCTTCTGTAAGGGCGAGTGCGCGTGGGGGGGCGTCATGAACGTGTCGGCGTGCCGCTTCGGCTCCCCCGCCTTCATCACCCTGCCGCACTTCCTGCACGGAGACCCCGCCCTGCTGGACCAGGTCACCGGCATGAACCCGGATCCGGACAAGCACTCGTTCTATTTCGCTGTCGAACCTAAACTGGGCGTCCCCATAGACGTGGCGGGCAGGTTTCAGTTCAATGTCTACGTGGAGCCGAGCGACCACATCACATTGTATGAGAACATGCCACGGATGCTGTTCCCGGTGTTCTGGGTGGAACAGAAGGCCAAGATCGATCCAAAAATCATTTCGGAGCTGAGGACGGTACGCGGTATCCTGGACTGGGGCCCGACCTTCTGCGCTTGCTTCGCCGTCGTGATAGCGTTGCTGGTGACCGCCATCACGTGCTGCACCAAGCGAACAGAGTACACGCGGCCCCACGACCTCCTCAAGCCCTACGAGAAGCCCAAAGACGAAGCGGAAATGAAACTGAATCCTATATGA

Protein

MVLPTMRGGLLRWRSLWICGGALLALSAFVAALTWGAIFDSAFGSQLALIPDSRSFMRWLEPDVPIFFDIYMFNWTNPERFPEEKPNFEEIGPYRYQEHRRHVNISWHPENGTIGYRTLRSWVWDESSVGSQDDIITTIDVITASAIYQARFSGFIEQKLVSLTLTSSQHTKVSVTARASEFLFEGYEDPLLNLAKLMPASVRGGAPALDRFGWFFSRNNTDTDGYMEVTSGTRDGLPGQILRWNYQDHIPFYDGECSKLSGSAGEYIPRNLTEDSKLTMYVPDLCRTVNMEFVESGVQNGLKYNKYEVNERSFDNSSTSPENTCFCKGECAWGGVMNVSACRFGSPAFITLPHFLHGDPALLDQVTGMNPDPDKHSFYFAVEPKLGVPIDVAGRFQFNVYVEPSDHITLYENMPRMLFPVFWVEQKAKIDPKIISELRTVRGILDWGPTFCACFAVVIALLVTAITCCTKRTEYTRPHDLLKPYEKPKDEAEMKLNPI

Cofactor

Mo-molybdopterin

Subunit

Homodimer.

Similarity

Belongs to the CD36 family.

Uniprot

D2KXB3   H9JLS5   A0A2A4K5Z3   A0A2W1B692   A0A194QNC1   A0A194QJD4   + More
A0A3S2M4A8   A0A212EQ86   A0A212EYQ4   A0A0K8TZZ9   A0A034VKC3   A0A0A1WNN1   A0A1A9X966   A0A0L0CGH4   A0A1B0FQV0   A0A1A9V6W1   A0A1B0A5Z0   A0A1B0BTQ7   W8BKA5   A0A1L8DJS1   B4JQP9   A0A1L8DJQ4   A0A1I8M439   A0A1I8NNC5   A0A1I8NEQ5   T1PE34   B5DHP8   B3MKB1   A0A1W4W8W5   B4Q5P9   A0A0J9QXS0   B4HY65   A0A1J1J3Q3   A0A3B0JIH9   B4LS25   B4NZK4   A0A336MHS5   B4KKA9   A0A182NKS9   B3N6K2   A0A084WT04   A0A182MWX6   Q961H6   Q5TSL9   A0A1J1J101   B4MZV0   A0A182Y4K6   A0A182QHH3   Q9VM10   C9QPI3   A0A182TQQ9   A0A182HJP3   A0A182XKA0   A0A1B6DBG4   A0A146LM45   A0A0M4E9F4   A0A0A9WXH9   A0A182V9N6   A0A0A9XHB3   A0A0K8TI31   A0A0K8TH33   A0A182RDD8   U5EUH2   W8BEV2   A0A1Y1K6E5   A0A182JFA0   A0A1B6M942   A0A2J7RNS7   Q16YZ7   A0A1Q3G2V7   A0A1B6CTY0   A0A0A1XIJ8   A0A0P6K0V4   A0A1Q3G3A6   A0A1Q3G3F6   A0A182KWV8   A0A182GXY9   A0A1I8MJ10   A0A2M4BIL7   A0A182W0M9   W8B820   A0A2M4BI30   A0A182FR92   T1PD13   A0A2M4BGU5   A0A2M4CZG9   A0A2M4ARD6   W5JF85   A0A2M4CYT9   T1E8L2   A0A023EYU4   J3JXY8   U4UH84   N6TC26   A0A069DU93   A0A224XN65  

Pubmed

20053988    19121390    28756777    26354079    22118469    25348373    + More
25830018    26108605    24495485    17994087    25315136    15632085    22936249    17550304    18057021    24438588    12364791    25244985    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    26823975    25401762    28004739    17510324    26999592    20966253    26483478    20920257    23761445    25474469    22516182    23537049    26334808   

EMBL

AB515346    BAI66272.1    BABH01005164    NWSH01000120    PCG79334.1    KZ150455    + More
PZC70811.1    KQ461194    KPJ06854.1    KQ458671    KPJ05504.1    RSAL01000046    RVE50583.1    AGBW02013290    OWR43646.1    AGBW02011444    OWR46633.1    GDHF01032277    JAI20037.1    GAKP01016712    GAKP01016711    JAC42240.1    GBXI01013855    GBXI01013623    JAD00437.1    JAD00669.1    JRES01000438    KNC31312.1    CCAG010010711    JXJN01020311    JXJN01020312    GAMC01016552    GAMC01016551    JAB90004.1    GFDF01007376    JAV06708.1    CH916372    EDV99229.1    GFDF01007375    JAV06709.1    KA646213    AFP60842.1    CH379058    EDY69825.1    CH902620    EDV32495.2    CM000361    EDX04095.1    CM002910    KMY88772.1    KMY88773.1    CH480818    EDW51995.1    CVRI01000066    CRL06078.1    OUUW01000006    SPP82005.1    CH940649    EDW64711.1    CM000157    EDW87753.2    KRJ97378.1    UFQS01001313    UFQT01001313    SSX10284.1    SSX29972.1    CH933807    EDW12640.1    KRG03345.1    CH954177    EDV59218.2    ATLV01026789    KE525419    KFB53348.1    AXCM01000876    AY051582    AAK93006.1    AAAB01008904    EAA09639.4    CRL06079.1    CH963920    EDW77885.2    AXCN02000303    AE014134    AAF52518.3    AAN10632.2    BT100097    ACX70070.1    APCN01002194    GEDC01014353    JAS22945.1    GDHC01019015    GDHC01011169    JAP99613.1    JAQ07460.1    CP012523    ALC38826.1    GBHO01042072    GBHO01030457    JAG01532.1    JAG13147.1    GBHO01042077    GBHO01024563    JAG01527.1    JAG19041.1    GBRD01001011    JAG64810.1    GBRD01001012    JAG64809.1    GANO01002329    JAB57542.1    GAMC01014794    GAMC01014793    JAB91761.1    GEZM01095929    JAV55255.1    GEBQ01007530    JAT32447.1    NEVH01002148    PNF42490.1    CH477505    EAT39872.2    GFDL01000890    JAV34155.1    GEDC01020342    JAS16956.1    GBXI01010303    GBXI01010009    GBXI01006870    GBXI01003552    JAD03989.1    JAD04283.1    JAD07422.1    JAD10740.1    GDUN01000691    JAN95228.1    GFDL01000755    JAV34290.1    GFDL01000746    JAV34299.1    JXUM01020819    KQ560582    KXJ81808.1    GGFJ01003754    MBW52895.1    GAMC01013353    GAMC01013352    JAB93203.1    GGFJ01003327    MBW52468.1    KA645995    AFP60624.1    GGFJ01003135    MBW52276.1    GGFL01006443    MBW70621.1    GGFK01010036    MBW43357.1    ADMH02001656    ETN61545.1    GGFL01006324    MBW70502.1    GAMD01002663    JAA98927.1    GBBI01004365    JAC14347.1    BT128110    AEE63071.1    KB632161    ERL89265.1    APGK01043534    APGK01043535    APGK01043536    KB741015    ENN75288.1    GBGD01001196    JAC87693.1    GFTR01006833    JAW09593.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000283053    UP000007151    + More
UP000092443    UP000037069    UP000092444    UP000078200    UP000092445    UP000092460    UP000001070    UP000095301    UP000095300    UP000001819    UP000007801    UP000192221    UP000000304    UP000001292    UP000183832    UP000268350    UP000008792    UP000002282    UP000009192    UP000075884    UP000008711    UP000030765    UP000075883    UP000007062    UP000007798    UP000076408    UP000075886    UP000000803    UP000075902    UP000075840    UP000076407    UP000092553    UP000075903    UP000075900    UP000075880    UP000235965    UP000008820    UP000075882    UP000069940    UP000249989    UP000075920    UP000069272    UP000000673    UP000030742    UP000019118   

PRIDE

D2KXB3    H9JLS5    Q961H6    Q9VM10    C9QPI3   

Pfam

PF01130   CD36        + More
PF10223   DUF2181
PF03404   Mo-co_dimer
PF00173   Cyt-b5
PF00174   Oxidored_molyb

Interpro

IPR002159   CD36_fam        + More
IPR019356   DUF2181       
IPR001199   Cyt_B5-like_heme/steroid-bd       
IPR022407   OxRdtase_Mopterin_BS       
IPR014756   Ig_E-set       
IPR008335   Mopterin_OxRdtase_euk       
IPR036400   Cyt_B5-like_heme/steroid_sf       
IPR000572   OxRdtase_Mopterin-bd_dom       
IPR036374   OxRdtase_Mopterin-bd_sf       
IPR005066   MoCF_OxRdtse_dimer       
IPR005428   CD36/SCARB1/SNMP1       

SUPFAM

SSF55856   SSF55856        + More
SSF81296   SSF81296       
SSF56524   SSF56524       

Gene 3D

3.10.120.10     3.90.420.10    

ProteinModelPortal

D2KXB3   H9JLS5   A0A2A4K5Z3   A0A2W1B692   A0A194QNC1   A0A194QJD4   + More
A0A3S2M4A8   A0A212EQ86   A0A212EYQ4   A0A0K8TZZ9   A0A034VKC3   A0A0A1WNN1   A0A1A9X966   A0A0L0CGH4   A0A1B0FQV0   A0A1A9V6W1   A0A1B0A5Z0   A0A1B0BTQ7   W8BKA5   A0A1L8DJS1   B4JQP9   A0A1L8DJQ4   A0A1I8M439   A0A1I8NNC5   A0A1I8NEQ5   T1PE34   B5DHP8   B3MKB1   A0A1W4W8W5   B4Q5P9   A0A0J9QXS0   B4HY65   A0A1J1J3Q3   A0A3B0JIH9   B4LS25   B4NZK4   A0A336MHS5   B4KKA9   A0A182NKS9   B3N6K2   A0A084WT04   A0A182MWX6   Q961H6   Q5TSL9   A0A1J1J101   B4MZV0   A0A182Y4K6   A0A182QHH3   Q9VM10   C9QPI3   A0A182TQQ9   A0A182HJP3   A0A182XKA0   A0A1B6DBG4   A0A146LM45   A0A0M4E9F4   A0A0A9WXH9   A0A182V9N6   A0A0A9XHB3   A0A0K8TI31   A0A0K8TH33   A0A182RDD8   U5EUH2   W8BEV2   A0A1Y1K6E5   A0A182JFA0   A0A1B6M942   A0A2J7RNS7   Q16YZ7   A0A1Q3G2V7   A0A1B6CTY0   A0A0A1XIJ8   A0A0P6K0V4   A0A1Q3G3A6   A0A1Q3G3F6   A0A182KWV8   A0A182GXY9   A0A1I8MJ10   A0A2M4BIL7   A0A182W0M9   W8B820   A0A2M4BI30   A0A182FR92   T1PD13   A0A2M4BGU5   A0A2M4CZG9   A0A2M4ARD6   W5JF85   A0A2M4CYT9   T1E8L2   A0A023EYU4   J3JXY8   U4UH84   N6TC26   A0A069DU93   A0A224XN65  

PDB

6I2K     E-value=3.31709e-42,     Score=433

KEGG

100328605    no KO assigned | (RefSeq) SCRB4, BmSCRB4, Cameo2; scavenger receptor class B member 4

GO

GO:0016021   GO:0007602   GO:0043052   GO:0016063   GO:0016116   GO:0043546   GO:0016491   GO:0042128   GO:0030151   GO:0016020   GO:0003700   GO:0005667   GO:0007179   GO:0005515   GO:0004319   GO:0004320   GO:0016295   GO:0016296  

PANTHER

PTHR11923  

Length:

499

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

45.0166699999999

Exp number, first 60 AAs:

22.82379

Total prob of N-in:

0.99772

POSSIBLE N-term signal

sequence

inside

1  -  12

TMhelix

13  -  35

outside

36  -  446

TMhelix

447  -  469

inside

470  -  499

 

 

Pi

197.505991

Theta

18.975959

Tajima's D

-1.213726

CLR

1.426228

CSRT

0.0998950052497375

Interpretation

Uncertain