Gene

KWMTBOMO06954  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010306

Annotation

PREDICTED:_venom_protease-like_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr12(+):283696-289282      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 2.701

CDS

ATGTTGGCCTTTGCTTCGTCTCGGGATATCGCTCTCATCGCTGTCACAGGAGGGGGTGCTAACGCTCAGTCGCGGCACAGTCGCGGTGCCGGTCTGTGCGCACACAAGATGTCTCGTGCCGCGTTCGTGCTGGGGTCTGTGCTTCTTTCCTACTTCAGAAGTACCGTGGCTGATGTTGAAGGGGCCCGGTGTGTCCGCGACGGCTACAACGGCACGTGCGTGCTAAGCAAGCGCTGCGAGACACTCATCCTGGACTACAGGGATAGATCCTTCCCGCCGGTGTGCGGGCTTCGCGGCAAGGAGCCCATCGTGTGCTGCACCGACTGTGAGCTCGTGGACAACATCGATAATATATATCTGACCAAAAAATACGGCCGACTGGAAAAAATAAACAAAAAATCTTGGGACGCTTGCATCGACAACGTTTTGAACATACCATCATATTTATGTCAAAGCTCCACTACTTTTGACTTCGATAAATACTGGGATGTTAAAAAAAAATGTCACAAAATAAATCTGTCGTTGGTAGCACCGGCCGGCGGTAAAGACGCCGAAAGAGCGGAGTTCCCCTTCATGGCGCTGCTGGGGTTCGGACCGAGCGCAGAGGAGGCGCAGTGGCTGTGCGGCGGGTCGGTGCTCTCCGCGCGGTACATCCTCACGGCGGCGCACTGCATCTCCGAGCCACGCCTGGGACCCTTGAAGTACGCAGCTCTCGGCATCCTGAAGCGCTCCGACCCTCCTGAGATCTGGCAGCGGCACACCCTCGCCCAGGTCATCCCGCACCCCGACTACGCCTCGCCCTCCAAGTACCACGACATCGCGCTCCTCAAGACCCAGAAACAAATACAATTCAACGTCAACGTGGTGCCCGCGTGCTTGTATTCTGGTGAGAAGAAGCGCAACATCGATCCAAGTCGAGCTCTGGCCCTGGGCTGGGGTTACCTCGGACCAAATACACAATTAGCTGATGTTCTACAGAAGGTTGAAGTGAGCGAGTTCACCGCTGAGGAGTGTTCGACACGCTACCCTTCGAACCGACACATGCTCGACGGGTTCGACAACAGCACGCAGTTGTGCTACGGAGACCGCAAGATGACGCGCGACACTTGCCAGGGCGATAGCGGCGGACCCTTGATCCTGCATCAAAGTGAGGTGGGCTGCGCGAAGGCAGTGTTCGGCGTGACGTCATCAGGCGTGGAGTGTGACGAAGCTACTGCAGGCCTCTACACGCGCGTCGAGCACTACAAGCCCTGGATCGAGAGCATCGTCTGGCCTTGA

Protein

MLAFASSRDIALIAVTGGGANAQSRHSRGAGLCAHKMSRAAFVLGSVLLSYFRSTVADVEGARCVRDGYNGTCVLSKRCETLILDYRDRSFPPVCGLRGKEPIVCCTDCELVDNIDNIYLTKKYGRLEKINKKSWDACIDNVLNIPSYLCQSSTTFDFDKYWDVKKKCHKINLSLVAPAGGKDAERAEFPFMALLGFGPSAEEAQWLCGGSVLSARYILTAAHCISEPRLGPLKYAALGILKRSDPPEIWQRHTLAQVIPHPDYASPSKYHDIALLKTQKQIQFNVNVVPACLYSGEKKRNIDPSRALALGWGYLGPNTQLADVLQKVEVSEFTAEECSTRYPSNRHMLDGFDNSTQLCYGDRKMTRDTCQGDSGGPLILHQSEVGCAKAVFGVTSSGVECDEATAGLYTRVEHYKPWIESIVWP

Similarity

Belongs to the peptidase S1 family.
Belongs to the PI3/PI4-kinase family.

Uniprot

H9JLA5   A0A2A4IWJ7   A0A2A4JLI0   A0A2A4J4P7   Q5MPB6   A0A2W1BD72   + More
A0A2W1BHZ8   A0A2W1B9D9   A0A2H1VJG7   A0A2W1B0L2   A0A2H1VFF0   A0A2A4K2L1   A0A2H1W424   A0A2W1BFG9   A0A2W1AYZ6   A0A2A4J7N6   A0A2A4K714   A0A2W1B9E2   A0A2A4JMC3   A0A2H1VTL8   A0A2H1V6L6   A0A2W1BCP3   A0A2A4J0N6   A0A2H1VA97   A0A2W1B5J0   A0A2A4KAM6   A0A2W1B6U7   A0A2H1VSY3   F5BZV1   A0A2A4KAK6   A0A0N1PHF7   A0A2A4K1V9   A0A2A4JAR5   A0A3S2NPZ4   A0A2W1BB28   A0A2W1BDD3   A0A194QB71   S4NXP2   A0A346RAE0   A0A194Q9Z8   A0A194Q9Q9   Q5MPB3   A0A2W1B2N2   Q5MPB2   H9JJA9   A0A2A4K236   O44331   A0A0N0PDL6   U5ESE3   A0A2H1WB67   A0A0N1IHL2   B1B5K0   A0A1Y1KAU3   A0A1Y1KPC1   D6WCU1   Q16NE9   Q5MPC1   A0A336LYA5   U4UP36   A0A182S507   A0A1B6LG03   A0A1B6DI71   A0A182XUQ8   A0A182KNG1   Q5TNC5   A0A182IIN2   A0A1B6LJF7   B0W1A9   A0A1B6CQN4   A0A182NZ25   A0A0T6B4N8   A0A182VNZ6   A0A182FZY7   A0A182THH3   A0A1B6DVZ4  

Pubmed

19121390    15944088    28756777    26354079    23622113    29910977    + More
9927173    18195005    28004739    18362917    19820115    17510324    23537049    20966253    12364791   

EMBL

BABH01038780    NWSH01005248    PCG64337.1    NWSH01001045    PCG72935.1    NWSH01003268    + More
PCG66648.1    AY672794    AAV91016.1    KZ150344    PZC71287.1    PZC71293.1    KZ150484    PZC70714.1    ODYU01002903    SOQ40975.1    KZ150503    PZC70659.1    ODYU01002282    SOQ39557.1    NWSH01000265    PCG77882.1    ODYU01006166    SOQ47783.1    KZ150189    PZC72424.1    KZ150652    PZC70412.1    NWSH01002560    PCG67981.1    NWSH01000060    PCG80065.1    KZ150324    PZC71401.1    PCG72936.1    ODYU01004086    SOQ43594.1    ODYU01000940    SOQ36457.1    KZ150278    PZC71645.1    NWSH01004041    PCG65541.1    ODYU01001487    SOQ37759.1    PZC70661.1    NWSH01000008    PCG80964.1    KZ150429    PZC70911.1    SOQ43592.1    JF431073    AEB21638.1    PCG80944.1    KQ460127    KPJ17583.1    PCG77884.1    NWSH01002139    PCG69061.1    RSAL01000491    RVE41548.1    KZ150531    PZC70597.1    PZC70910.1    KQ459249    KPJ02240.1    GAIX01012077    JAA80483.1    MH200930    AXS59140.1    KPJ02244.1    KPJ02243.1    AY672797    AAV91019.1    KZ150408    PZC70992.1    AY672798    AAV91020.1    BABH01036383    BABH01036384    BABH01036385    BABH01036386    BABH01036387    BABH01036388    BABH01036389    BABH01036390    BABH01036391    NWSH01000257    PCG77964.1    AF017664    AAB94558.1    KQ460130    KPJ17530.1    GANO01003282    JAB56589.1    ODYU01007499    SOQ50321.1    KPJ17576.1    AB363979    BAG14261.1    GEZM01092351    JAV56586.1    GEZM01077598    JAV63253.1    KQ971311    EEZ99357.2    CH477825    EAT35883.2    AY672789    AAV91011.1    UFQT01000075    UFQT01000299    SSX19399.1    SSX22964.1    KB632306    ERL91906.1    GEBQ01017356    JAT22621.1    GEDC01011978    JAS25320.1    AAAB01008984    EAL38946.3    APCN01003350    GEBQ01016151    JAT23826.1    DS231821    EDS44979.1    GEDC01021600    JAS15698.1    LJIG01009813    KRT82329.1    GEDC01007444    JAS29854.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000283053    UP000053268    UP000007266    + More
UP000008820    UP000030742    UP000075900    UP000076407    UP000075882    UP000007062    UP000075840    UP000002320    UP000075884    UP000075903    UP000069272    UP000075902   

PRIDE

H9JLA5    F5BZV1    H9JJA9   

Pfam

PF00089   Trypsin        + More
PF00454   PI3_PI4_kinase

Interpro

IPR001254   Trypsin_dom        + More
IPR018114   TRYPSIN_HIS       
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR033116   TRYPSIN_SER       
IPR022700   CLIP       
IPR000403   PI3/4_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR036940   PI3/4_kinase_cat_sf       
IPR038565   CLIP_sf       

SUPFAM

SSF50494   SSF50494        + More
SSF56112   SSF56112       

Gene 3D

1.10.1070.11     2.20.20.90    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9JLA5   A0A2A4IWJ7   A0A2A4JLI0   A0A2A4J4P7   Q5MPB6   A0A2W1BD72   + More
A0A2W1BHZ8   A0A2W1B9D9   A0A2H1VJG7   A0A2W1B0L2   A0A2H1VFF0   A0A2A4K2L1   A0A2H1W424   A0A2W1BFG9   A0A2W1AYZ6   A0A2A4J7N6   A0A2A4K714   A0A2W1B9E2   A0A2A4JMC3   A0A2H1VTL8   A0A2H1V6L6   A0A2W1BCP3   A0A2A4J0N6   A0A2H1VA97   A0A2W1B5J0   A0A2A4KAM6   A0A2W1B6U7   A0A2H1VSY3   F5BZV1   A0A2A4KAK6   A0A0N1PHF7   A0A2A4K1V9   A0A2A4JAR5   A0A3S2NPZ4   A0A2W1BB28   A0A2W1BDD3   A0A194QB71   S4NXP2   A0A346RAE0   A0A194Q9Z8   A0A194Q9Q9   Q5MPB3   A0A2W1B2N2   Q5MPB2   H9JJA9   A0A2A4K236   O44331   A0A0N0PDL6   U5ESE3   A0A2H1WB67   A0A0N1IHL2   B1B5K0   A0A1Y1KAU3   A0A1Y1KPC1   D6WCU1   Q16NE9   Q5MPC1   A0A336LYA5   U4UP36   A0A182S507   A0A1B6LG03   A0A1B6DI71   A0A182XUQ8   A0A182KNG1   Q5TNC5   A0A182IIN2   A0A1B6LJF7   B0W1A9   A0A1B6CQN4   A0A182NZ25   A0A0T6B4N8   A0A182VNZ6   A0A182FZY7   A0A182THH3   A0A1B6DVZ4  

PDB

2OLG     E-value=6.81275e-29,     Score=317

KEGG

101743260    no KO assigned | (RefSeq) venom protease-like

GO

GO:0004252   GO:0016021   GO:0008236   GO:0016301   GO:0006508   GO:0016192   GO:0005484   GO:0006886   GO:0004317   GO:0004319   GO:0004320   GO:0016295   GO:0016296  

Length:

425

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.09273

Exp number, first 60 AAs:

0.09162

Total prob of N-in:

0.00719

outside

1  -  425

 

 

Pi

69.650645

Theta

134.183981

Tajima's D

-0.912719

CLR

0.26932

CSRT

0.155142242887856

Interpretation

Uncertain