Gene

KWMTBOMO06953  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010306

Annotation

PREDICTED:_venom_protease-like_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr12(+):267536-271567      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.5 Extracellular   Reliability : 1.406

CDS

ATGAAAACTGCAGAACCAGTACACCTGGAAGACGTCGATCTTACAGACTTGAAGATCCTCTCATTCGCCCTGAAGAAAAGTTCCTATGGGATATCACCAGCCGGGGGTACAGCTGCCGAAAGAGCGGAGTTTCCTTTTATGGCGCTGCTGGGGTTCGGGGCGAGCGCGGAGGAGGCGCAGTGGCTGTGCGGCGGGTCGGTGCTTTCCGCGCGGTACATCCTCACGGCGGCGCACTGCATCTCCGAGCCACGCCTGGGACCCTTGAAGTACGCAGCTCTCGGCATCCTGAAGCGCTCCGACCCTCCTGAGATCTGGCAGCGGCACACCCTCGCCCAGGTCATCCCGCACCCTGACTACGCCTCGCCCTCCAAGTACCACGACATCGCGCTCCTCAAGACCGAGAAACAAATACAATTCAACATCAACGTGGTGCCCGCGTGCTTGTATTCTGGTGAGAAGAAGCGCAACATCGATCCAAGTCGAGCTCTGGCCCTGGGCTGGGGCTACCTCGGACCAAATACACGCCTAGCTGATGTCTTACAGAAGGTTGAAGTGAGCGAGTTCACCGCCGAGGAGTGCTTGACGCACTACCCTCCGCACCGCCACCTGCTCGACGGGTTCGACAACAGCACGCAGCTGTGCTACGGAGACCGCGACAAGACGCGCGACACTTGCCAGGGCGATAGCGGCGGTCCCTTGATCCTGCATAACAATGAGGTGGGCTGCGCGAAGGCAGTGTTCGGCGTGACGTCATCGGGCGTGGAGTGCGATGTAGCGACCGCCGGCCTCTACACGCGCGTCGAGCACTACAAGCCCTGGATCGAGAGCATCGTCTGGCCTTGA

Protein

MKTAEPVHLEDVDLTDLKILSFALKKSSYGISPAGGTAAERAEFPFMALLGFGASAEEAQWLCGGSVLSARYILTAAHCISEPRLGPLKYAALGILKRSDPPEIWQRHTLAQVIPHPDYASPSKYHDIALLKTEKQIQFNINVVPACLYSGEKKRNIDPSRALALGWGYLGPNTRLADVLQKVEVSEFTAEECLTHYPPHRHLLDGFDNSTQLCYGDRDKTRDTCQGDSGGPLILHNNEVGCAKAVFGVTSSGVECDVATAGLYTRVEHYKPWIESIVWP

Similarity

Belongs to the peptidase S1 family.
Belongs to the PI3/PI4-kinase family.

Uniprot

H9JLA5   H9JLA2   A0A2A4J4P7   A0A2A4IWJ7   A0A2A4JLI0   A0A2H1V6L6   + More
A0A2A4J4I5   A0A2W1B9D9   A0A2W1B4D4   A0A2W1BHZ8   A0A2A4IY52   A0A2W1BD72   A0A2W1B0L2   A0A2A4JMC3   Q5MPB6   A0A2H1VRC0   A0A2A4K2L1   A0A2W1BGC1   A0A2H1VJG7   A0A2H1W424   A0A2W1B2E4   A0A2W1B4D5   A0A2W1B9E2   A0A2H1VFF0   A0A2H1VSY3   A0A2W1BCP3   A0A2W1BFG9   A0A2A4J7N6   A0A2H1VTL8   A0A2A4K9I3   A0A2A4K714   A0A2A4KAM6   A0A2H1VFJ7   A0A2W1AYZ6   S4NXP2   A0A2A4K9N2   A0A194QB71   A0A0N1PHF7   A0A346RAE0   F5BZV1   A0A2W1BC76   A0A3S2NPZ4   A0A2H1VR51   A0A2A4KAK6   A0A2A4K749   A0A194Q9Q9   A0A2H1VA97   A0A2H1VJ99   Q5MPB2   Q5MPB3   A0A2W1B6U7   H9JJA9   A0A2W1B5J0   A0A0N0PDL6   A0A194Q9Z8   A0A2H1VS51   A0A2A4K236   A0A2A4K1V9   A0A2W1BB28   A0A2A4JAR5   A0A2W1B2N2   U5ESE3   A0A2W1BDH3   A0A2W1BDD3   I4DL86   O44331   A0A212F107   A0A2A4K113   B1B5K0   A0A1Y1KAU3   B0W1A9   Q16NE9   A0A336LYA5   A0A1Y1KPC1   A0A182KNG1   D6WCU1   A0A224XMI3   A0A182IIN2   Q5TNC5   A0A182XUQ8   A0A170XJQ4   A0A182S507   A0A182VNZ6   A0A0T6B0G9   B0XLJ6   A0A1Q3FNX1   A0A182NZ25   A0A182Q673   A0A182THH3   Q5MPC1   A0A182Y982   A0A195EZ94   A0A084VYF5   V5GMH2  

Pubmed

19121390    28756777    15944088    23622113    26354079    29910977    + More
22651552    9927173    22118469    18195005    28004739    17510324    20966253    18362917    19820115    12364791    25244985    24438588   

EMBL

BABH01038780    BABH01038773    BABH01038774    NWSH01003268    PCG66648.1    NWSH01005248    + More
PCG64337.1    NWSH01001045    PCG72935.1    ODYU01000940    SOQ36457.1    PCG66646.1    KZ150484    PZC70714.1    KZ150642    PZC70421.1    KZ150344    PZC71293.1    PCG64338.1    PZC71287.1    KZ150503    PZC70659.1    PCG72936.1    AY672794    AAV91016.1    ODYU01003947    SOQ43326.1    NWSH01000265    PCG77882.1    KZ150249    PZC71840.1    ODYU01002903    SOQ40975.1    ODYU01006166    SOQ47783.1    KZ150429    PZC70909.1    PZC71292.1    KZ150324    PZC71401.1    ODYU01002282    SOQ39557.1    ODYU01004086    SOQ43592.1    KZ150278    PZC71645.1    KZ150189    PZC72424.1    NWSH01002560    PCG67981.1    SOQ43594.1    NWSH01000008    PCG80945.1    NWSH01000060    PCG80065.1    PCG80964.1    SOQ39556.1    KZ150652    PZC70412.1    GAIX01012077    JAA80483.1    PCG80941.1    KQ459249    KPJ02240.1    KQ460127    KPJ17583.1    MH200930    AXS59140.1    JF431073    AEB21638.1    KZ150575    PZC70500.1    RSAL01000491    RVE41548.1    SOQ43323.1    PCG80944.1    PCG80061.1    KPJ02243.1    ODYU01001487    SOQ37759.1    ODYU01002875    SOQ40903.1    AY672798    AAV91020.1    AY672797    AAV91019.1    PZC70911.1    BABH01036383    BABH01036384    BABH01036385    BABH01036386    BABH01036387    BABH01036388    BABH01036389    BABH01036390    BABH01036391    PZC70661.1    KQ460130    KPJ17530.1    KPJ02244.1    ODYU01004095    SOQ43606.1    NWSH01000257    PCG77964.1    PCG77884.1    KZ150531    PZC70597.1    NWSH01002139    PCG69061.1    KZ150408    PZC70992.1    GANO01003282    JAB56589.1    PZC72431.1    PZC70910.1    AK402054    BAM18676.1    AF017664    AAB94558.1    AGBW02010978    OWR47436.1    PCG77965.1    AB363979    BAG14261.1    GEZM01092351    JAV56586.1    DS231821    EDS44979.1    CH477825    EAT35883.2    UFQT01000075    UFQT01000299    SSX19399.1    SSX22964.1    GEZM01077598    JAV63253.1    KQ971311    EEZ99357.2    GFTR01004132    JAW12294.1    APCN01003350    AAAB01008984    EAL38946.3    GEMB01004336    JAR98937.1    LJIG01016363    KRT80826.1    DS234510    EDS34246.1    GFDL01005857    JAV29188.1    AXCN02000734    AY672789    AAV91011.1    KQ981909    KYN33194.1    ATLV01018364    KE525231    KFB42999.1    GALX01005659    JAB62807.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000283053    UP000007151    + More
UP000002320    UP000008820    UP000075882    UP000007266    UP000075840    UP000007062    UP000076407    UP000075900    UP000075903    UP000075884    UP000075886    UP000075902    UP000076408    UP000078541    UP000030765   

PRIDE

H9JLA5    H9JLA2    F5BZV1    H9JJA9   

Pfam

PF00089   Trypsin        + More
PF00454   PI3_PI4_kinase

Interpro

IPR001254   Trypsin_dom        + More
IPR018114   TRYPSIN_HIS       
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR033116   TRYPSIN_SER       
IPR022700   CLIP       
IPR012224   Pept_S1A_FX       
IPR000403   PI3/4_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR036940   PI3/4_kinase_cat_sf       
IPR038565   CLIP_sf       

SUPFAM

SSF50494   SSF50494        + More
SSF56112   SSF56112       

Gene 3D

1.10.1070.11     2.20.20.90    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9JLA5   H9JLA2   A0A2A4J4P7   A0A2A4IWJ7   A0A2A4JLI0   A0A2H1V6L6   + More
A0A2A4J4I5   A0A2W1B9D9   A0A2W1B4D4   A0A2W1BHZ8   A0A2A4IY52   A0A2W1BD72   A0A2W1B0L2   A0A2A4JMC3   Q5MPB6   A0A2H1VRC0   A0A2A4K2L1   A0A2W1BGC1   A0A2H1VJG7   A0A2H1W424   A0A2W1B2E4   A0A2W1B4D5   A0A2W1B9E2   A0A2H1VFF0   A0A2H1VSY3   A0A2W1BCP3   A0A2W1BFG9   A0A2A4J7N6   A0A2H1VTL8   A0A2A4K9I3   A0A2A4K714   A0A2A4KAM6   A0A2H1VFJ7   A0A2W1AYZ6   S4NXP2   A0A2A4K9N2   A0A194QB71   A0A0N1PHF7   A0A346RAE0   F5BZV1   A0A2W1BC76   A0A3S2NPZ4   A0A2H1VR51   A0A2A4KAK6   A0A2A4K749   A0A194Q9Q9   A0A2H1VA97   A0A2H1VJ99   Q5MPB2   Q5MPB3   A0A2W1B6U7   H9JJA9   A0A2W1B5J0   A0A0N0PDL6   A0A194Q9Z8   A0A2H1VS51   A0A2A4K236   A0A2A4K1V9   A0A2W1BB28   A0A2A4JAR5   A0A2W1B2N2   U5ESE3   A0A2W1BDH3   A0A2W1BDD3   I4DL86   O44331   A0A212F107   A0A2A4K113   B1B5K0   A0A1Y1KAU3   B0W1A9   Q16NE9   A0A336LYA5   A0A1Y1KPC1   A0A182KNG1   D6WCU1   A0A224XMI3   A0A182IIN2   Q5TNC5   A0A182XUQ8   A0A170XJQ4   A0A182S507   A0A182VNZ6   A0A0T6B0G9   B0XLJ6   A0A1Q3FNX1   A0A182NZ25   A0A182Q673   A0A182THH3   Q5MPC1   A0A182Y982   A0A195EZ94   A0A084VYF5   V5GMH2  

PDB

2F83     E-value=8.25151e-28,     Score=306

KEGG

101738421    no KO assigned | (RefSeq) serine protease snake-like

GO

GO:0004252   GO:0016021   GO:0005509   GO:0007596   GO:0016301   GO:0008236   GO:0006508   GO:0016192   GO:0005484   GO:0006886   GO:0004317   GO:0004319   GO:0004320   GO:0016295   GO:0016296  

Length:

280

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01091

Exp number, first 60 AAs:

0.00596

Total prob of N-in:

0.02224

outside

1  -  280

 

 

Pi

143.064206

Theta

141.353382

Tajima's D

-0.612023

CLR

0.045202

CSRT

0.212939353032348

Interpretation

Uncertain