Gene

KWMTBOMO06890

Pre Gene Modal

BGIBMGA012005

Annotation

PREDICTED:_tRNA_dimethylallyltransferase?_mitochondrial-like_[Bombyx_mori]

Location

Bomo_Chr11(+):18858101-18871346      View in EpiBrowser

Full name

tRNA dimethylallyltransferase      

Alternative Name

Isopentenyl-diphosphate:tRNA isopentenyltransferase
hGRO1
tRNA isopentenyltransferase 1
tRNA isopentenyltransferase

Location in the cell

Nuclear   Reliability : 4.452

CDS

ATGGCTACTTTTATCTTGTTTCAGGATGTCCACGATAAGCGTCTTGACGCTCGCGTCGACTCGATGCTGGAAGCGGGCCTCATTGAGGAGCTGCTGGATTTCCACGAGAGGCACAACAGGCACCGGATACAGGACGGGAGCTCACCAGACTACACCAAAGGCGTTTTCCAAACTCTTGGCTTCAAAGAATTCCACGATTACCTGATGATGTCCGAAGACGAAAGGAATTCGGAGGCGGGCAAGAAACTACTGAAGACCAGCATTGAAAACATGAAGATGGCCACCCGGAGATACGCGAGACGTCAAAACAAAATGTTTCGTCAAAGATTTTTAGAACATCCCAGAAGAGAGGTGCCTTTAGTTTACGAATTGGACACTACAGATGTAACCAAATGGGATGAAAACGTGAAAAACAAGGCTATTAAAATAATAGAAAGTTTCATCAATAGCACTGATTCTGATGTTTTACCAATAAAACAGCATCTTCAAAGTGATAAACTGCATACAGACGGAAATTCTTTTAATTTTTGTGAAATTTGTAATCGAATCATAATAGGCGATAACGTTTATGCTATTCATTTAAAATCTGTGCGTCACATGAAGGTTTTAAAGAAAATGAGATCACAAAACAAGGAACAAAAACAAGATTAA

Protein

MATFILFQDVHDKRLDARVDSMLEAGLIEELLDFHERHNRHRIQDGSSPDYTKGVFQTLGFKEFHDYLMMSEDERNSEAGKKLLKTSIENMKMATRRYARRQNKMFRQRFLEHPRREVPLVYELDTTDVTKWDENVKNKAIKIIESFINSTDSDVLPIKQHLQSDKLHTDGNSFNFCEICNRIIIGDNVYAIHLKSVRHMKVLKKMRSQNKEQKQD

Description

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).

Catalytic Activity

adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA

Similarity

Belongs to the IPP transferase family.

Keywords

Alternative splicing   ATP-binding   Complete proteome   Cytoplasm   Disease mutation   Metal-binding   Mitochondrion   Nucleotide-binding   Phosphoprotein   Polymorphism   Primary mitochondrial disease   Reference proteome   Transferase   Transit peptide   tRNA processing   Zinc   Zinc-finger   Nucleus  

Feature

chain  tRNA dimethylallyltransferase
splice variant  In isoform 2 and isoform 3.
sequence variant  In COXPD35.

Uniprot

A0A2H1VZD8   A0A2A4J9M1   A0A194QR76   A0A194Q9E8   K7J5P2   D6WDB1   + More
A0A154PPN4   A0A3L8DGV1   A0A212F819   A0A151IXH3   A0A195CY49   A0A087ZX87   A0A1B6E6L8   A0A224XJA2   A0A1W4XCH3   A0A069DQG6   A0A067R5L3   A0A151XH91   A0A158P2W8   N6TRD4   A0A3R7MJU5   A0A023FXU1   A0A1Y1M5B9   A0A0C9PRS7   U4U1W4   A0A2A3EI31   A0A2R5L5Q2   A0A195EZX8   A0A2I3LRI4   A0A3Q7X4X4   A0A2K6B163   A0A2K5U7C2   F7FQY3   A0A2J7QBD1   A0A2K5Z319   A0A384DT44   F6XBX7   A0A0D9S7N8   A0A2K5DYS2   A0A096MMW7   A0A2K5KC61   A0A2K5DYZ9   Q9H3H1-2   A0A2J8Y697   A0A3Q7XYH3   Q80UN9-2   A0A2K6B154   F7GJT8   I7G8M2   A0A2I2Z503   A0A2F0AWM5   H9F4Y3   G7NUC5   G7MG98   Q9H3H1-3   M3W562   A0A2K5RFZ3   A0A2K5Z325   A0A2K5DZ25   Q3T7C5   A0A2R8ZLW7   A0A2I3RL05   A0A2Y9J4F2   A0A1S3WGH9   G1LCG9   A0A3Q7P9Y3   G3HN83   D2HXL8   A0A2I3HS54   H9G668   A0A384DTX5   Q9H3H1-5   U3FSI0   M7BJR6   G1SGQ1   A0A1E1X3E8   A0A2K5KC58   H2N7V3   A0A1Z5L5F8   A0A2Y9IZV5   G3R3K0   A0A2K5DYN8   A0A2J8Y6C7   A0A3Q0DFI2   Q3T7C7   A0A293LL16   A0A2K5RFT6   A0A2K6EWL2   A0A1S3F8M3   A0A2R8ZPL5   H2PYR3   G1RN30   Q53F11   A0A1B6EHY5   Q9H3H1   A0A1Y1M5G9   M3YS73   A0A2K6MUL4  

EC Number

2.5.1.75

Pubmed

26354079    20075255    18362917    19820115    30249741    22118469    + More
26334808    24845553    21347285    23537049    28004739    17431167    11111046    15870694    14702039    16710414    15489334    11560893    17081983    20068231    21269460    21406692    23186163    24901367    28185376    16141072    19468303    17194215    22398555    25319552    22002653    17975172    22722832    16136131    20010809    21804562    21881562    25243066    23624526    21993624    28503490    28528879    8125298    9373149   

EMBL

ODYU01005400    SOQ46195.1    NWSH01002394    PCG68378.1    KQ461185    KPJ07480.1    + More
KQ459252    KPJ02137.1    KQ971321    EEZ99485.2    KQ435012    KZC13841.1    QOIP01000009    RLU19149.1    AGBW02009812    OWR49868.1    KQ980801    KYN12801.1    KQ977185    KYN05074.1    GEDC01003753    JAS33545.1    GFTR01003860    JAW12566.1    GBGD01002739    JAC86150.1    KK852729    KDR17577.1    KQ982130    KYQ59727.1    ADTU01007582    ADTU01007583    ADTU01007584    ADTU01007585    ADTU01007586    ADTU01007587    ADTU01007588    ADTU01007589    ADTU01007590    ADTU01007591    APGK01057365    KB741280    ENN70881.1    QCYY01000659    ROT83645.1    GBBL01001782    JAC25538.1    GEZM01040044    GEZM01040042    JAV80972.1    GBYB01004068    JAG73835.1    KB631604    ERL84601.1    KZ288237    PBC31377.1    GGLE01000692    MBY04818.1    KQ981905    KYN33429.1    AHZZ02015817    AHZZ02015818    AQIA01004583    AQIA01004584    AQIA01004585    AQIA01004586    AQIA01004587    JSUE03001184    JSUE03001185    NEVH01016301    PNF25887.1    AQIB01144671    AQIB01144672    AQIB01144673    AQIB01144674    AF074918    AY702944    AY702945    AY303390    AK000068    CR457226    AL033527    BC010741    BC107569    BC128155    AY052768    NDHI03003278    PNJ89802.1    AK003556    AL606906    BC019812    BC051040    AB170647    BAE87710.1    CABD030002601    CABD030002602    CABD030002603    NTJE010014569    MBV95139.1    JU325936    AFE69692.1    CM001276    EHH49804.1    CM001253    EHH14644.1    AANG04003279    AY702935    AAW63396.1    AJFE02051312    AJFE02051313    AJFE02051314    AJFE02051315    AJFE02051316    AJFE02051317    AJFE02051318    AJFE02051319    AACZ04033017    NBAG03000275    PNI52424.1    ACTA01098509    JH000537    EGV92584.1    GL193633    EFB13518.1    ADFV01076468    ADFV01076469    AAWZ02028779    AAWZ02028780    GAMS01009588    GAMR01008134    GAMP01002514    JAB13548.1    JAB25798.1    JAB50241.1    KB563787    EMP28447.1    AAGW02003112    AAGW02003113    GFAC01005403    JAT93785.1    ABGA01074454    ABGA01074455    PNJ89796.1    GFJQ02004317    JAW02653.1    PNJ89801.1    AY702933    AAW63394.1    GFWV01003791    MAA28521.1    GABE01011185    JAA33554.1    PNI52422.1    AK223478    BAD97198.1    GECZ01032222    JAS37547.1    GEZM01040043    JAV80973.1    AEYP01007632    AEYP01007633    AEYP01007634    AEYP01007635   

Proteomes

UP000218220    UP000053240    UP000053268    UP000002358    UP000007266    UP000076502    + More
UP000279307    UP000007151    UP000078492    UP000078542    UP000005203    UP000192223    UP000027135    UP000075809    UP000005205    UP000019118    UP000283509    UP000030742    UP000242457    UP000078541    UP000028761    UP000286642    UP000233120    UP000233100    UP000006718    UP000235965    UP000233140    UP000261680    UP000008225    UP000029965    UP000233020    UP000233080    UP000005640    UP000000589    UP000001519    UP000009130    UP000011712    UP000233040    UP000240080    UP000002277    UP000248482    UP000079721    UP000008912    UP000286641    UP000001075    UP000001073    UP000001646    UP000031443    UP000001811    UP000001595    UP000189706    UP000233160    UP000081671    UP000000715    UP000233180   

PRIDE

Q9H3H1    Q80UN9    G3HN83    Q3T7C7   

Pfam

PF01715   IPPT        + More
PF12171   zf-C2H2_jaz

Interpro

IPR018022   IPT        + More
IPR039657   Dimethylallyltransferase       
IPR036236   Znf_C2H2_sf       
IPR027417   P-loop_NTPase       
IPR030666   IPP_transferase_euk       
IPR022755   Znf_C2H2_jaz       
IPR003604   Matrin/U1-like-C_Znf_C2H2       
IPR013087   Znf_C2H2_type       

SUPFAM

SSF57667   SSF57667        + More
SSF52540   SSF52540       

ProteinModelPortal

A0A2H1VZD8   A0A2A4J9M1   A0A194QR76   A0A194Q9E8   K7J5P2   D6WDB1   + More
A0A154PPN4   A0A3L8DGV1   A0A212F819   A0A151IXH3   A0A195CY49   A0A087ZX87   A0A1B6E6L8   A0A224XJA2   A0A1W4XCH3   A0A069DQG6   A0A067R5L3   A0A151XH91   A0A158P2W8   N6TRD4   A0A3R7MJU5   A0A023FXU1   A0A1Y1M5B9   A0A0C9PRS7   U4U1W4   A0A2A3EI31   A0A2R5L5Q2   A0A195EZX8   A0A2I3LRI4   A0A3Q7X4X4   A0A2K6B163   A0A2K5U7C2   F7FQY3   A0A2J7QBD1   A0A2K5Z319   A0A384DT44   F6XBX7   A0A0D9S7N8   A0A2K5DYS2   A0A096MMW7   A0A2K5KC61   A0A2K5DYZ9   Q9H3H1-2   A0A2J8Y697   A0A3Q7XYH3   Q80UN9-2   A0A2K6B154   F7GJT8   I7G8M2   A0A2I2Z503   A0A2F0AWM5   H9F4Y3   G7NUC5   G7MG98   Q9H3H1-3   M3W562   A0A2K5RFZ3   A0A2K5Z325   A0A2K5DZ25   Q3T7C5   A0A2R8ZLW7   A0A2I3RL05   A0A2Y9J4F2   A0A1S3WGH9   G1LCG9   A0A3Q7P9Y3   G3HN83   D2HXL8   A0A2I3HS54   H9G668   A0A384DTX5   Q9H3H1-5   U3FSI0   M7BJR6   G1SGQ1   A0A1E1X3E8   A0A2K5KC58   H2N7V3   A0A1Z5L5F8   A0A2Y9IZV5   G3R3K0   A0A2K5DYN8   A0A2J8Y6C7   A0A3Q0DFI2   Q3T7C7   A0A293LL16   A0A2K5RFT6   A0A2K6EWL2   A0A1S3F8M3   A0A2R8ZPL5   H2PYR3   G1RN30   Q53F11   A0A1B6EHY5   Q9H3H1   A0A1Y1M5G9   M3YS73   A0A2K6MUL4  

PDB

3EPL     E-value=9.17429e-18,     Score=218

KEGG

101746847    K00791 tRNA dimethylallyltransferase [EC:2.5.1.75] | (RefSeq) tRNA dimethylallyltransferase, mitocho

PATHWAY

01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0008033   GO:0016740   GO:0052381   GO:0008270   GO:0005524   GO:0003676   GO:0005737   GO:0006400   GO:0005739   GO:0046872   GO:0016021   GO:0005759   GO:0070900   GO:0005634   GO:0015074   GO:0006355   GO:0022891   GO:0043565   GO:0016567   GO:0016020   GO:0006260  

PANTHER

PTHR11088  

Subcellular location

Mitochondrion  
Cytoplasm  
Nucleus  

Length:

216

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00444

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02915

outside

1  -  216

 

 

Pi

19.526511

Theta

17.340329

Tajima's D

0.327145

CLR

0.684099

CSRT

0.468576571171441

Interpretation

Uncertain