SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO06879  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA012075
Annotation
PREDICTED:_glycine_cleavage_system_H_protein?_mitochondrial-like_isoform_X2_[Papilio_machaon]
Full name
Glycine cleavage system H protein       + More
Glycine cleavage system H protein, mitochondrial      
Alternative Name
Protein pumpless
Location in the cell
Nuclear   Reliability : 1.893
 

Sequence

CDS
ATGGCAATACAGAGATGCTTATTACAAATAGTGAAAACTTACAAATTAAGGCATCATTTACAGTCAAACATCAGACAAACATACTGTATGTTATGCCTGAAGTACAGCACAGGTGGATCATCAAGGAAATATACTGATAGACATGAATGGGTTACAATAGACAAAGATATAGGTACAGTTGGGGTTAGCGAATATGCCCAAGAATCTCTTGGTGATGTTGTTTTTGCACAGCTGCCAGACCCCGGAACAGACCTTAAAGCTGGTGATGAGTGCGGTGCCTTAGAAAGTGTGAAAGCTGCTAGTGAAATCTATTCTCCATTATCTGGTACTGTTACGGAGAAAAATAAAGATGTAGAAGACAAACCCGCACTAATAAATACATCTTGTTATGACAAAGGATGGTTGTTTAGGTTGAAAATAATTAAGCAAAGCGAGATAAATGATCTCATGACTGAAGAAGAGTACAAGAAATTTTTGGAAACAGATGCTGAGAAACCAGAATAA
Protein
MAIQRCLLQIVKTYKLRHHLQSNIRQTYCMLCLKYSTGGSSRKYTDRHEWVTIDKDIGTVGVSEYAQESLGDVVFAQLPDPGTDLKAGDECGALESVKAASEIYSPLSGTVTEKNKDVEDKPALINTSCYDKGWLFRLKIIKQSEINDLMTEEEYKKFLETDAEKPE

Summary

Description
The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity).
Cofactor
(R)-lipoate
Subunit
The glycine cleavage system is composed of four proteins: P, T, L and H.
Similarity
Belongs to the GcvH family.
Keywords
Complete proteome   Lipoyl   Mitochondrion   Reference proteome   Transit peptide  
Feature
chain  Glycine cleavage system H protein, mitochondrial
EMBL
BABH01016071    GAIX01003259    JAA89301.1    KQ461185    KPJ07473.1    AP017502    + More
BBB06797.1    KQ459252    KPJ02146.1    JTDY01000138    KOB78644.1    NWSH01000295    PCG77662.1    AK401774    BAM18396.1    ODYU01000597    SOQ35667.1    GFDG01002114    JAV16685.1    GGFL01014790    MBW78968.1    GAMD01002900    JAA98690.1    GGFK01007289    MBW40610.1    GGFL01014891    MBW79069.1    DS232603    EDS43954.1    AXCN02000477    ATLV01024498    KE525352    KFB51485.1    GGFM01004201    MBW24952.1    AXCM01002601    GGFM01008387    MBW29138.1    GGFJ01010112    MBW59253.1    GGFJ01010113    MBW59254.1    GGFJ01010111    MBW59252.1    ADMH02001752    ETN61173.1    GFDL01009661    JAV25384.1    GAKP01008907    JAC50045.1    GDHF01019887    JAI32427.1    AJVK01063079    AAAB01008960    EAA44254.4    APCN01002303    GBXI01013873    JAD00419.1    GBXI01003671    JAD10621.1    GBXI01007783    JAD06509.1    GFDL01009652    JAV25393.1    AJWK01025711    GFDF01001114    JAV12970.1    CH933809    EDW18253.1    LNIX01000001    OXA64159.1    JRES01000036    KNC34708.1    CH477955    EAT34816.1    CH964101    EDW79468.1    KZ150031    PZC74731.1    CH477191    EAT48628.1    NWSH01000836    PCG73935.1    BT127256    AEE62218.1    EZ422516    ADD18792.1    CP012525    ALC44193.1    GANO01003393    JAB56478.1    CH940647    EDW70628.1    JXJN01008626    OUUW01000009    SPP85332.1    ODYU01003024    SOQ41273.1    JXUM01072026    KQ562697    KXJ75313.1    CH379069    EAL29812.1    GEDV01001772    JAP86785.1    CH479212    EDW33209.1    KQ460953    KPJ10319.1    GAMC01004821    JAC01735.1    CVRI01000058    CRL02934.1    JH431850    GFPF01008075    MAA19221.1    GEFH01003908    JAP64673.1    GACK01006266    JAA58768.1    CH902618    EDV39756.1    KQ459599    KPI94311.1    CH916366    EDV96881.1    GL451202    EFN79759.1    KK111147    EZA46469.1    NEVH01002140    PNF42630.1    AK418025    BAN21240.1    GL443346    EFN62158.1    EZ406118    ACX53917.1    CH480826    EDW44332.1    CM000363    CM002912    EDX11354.1    KMZ00960.1    BABH01031223    AF203725    AE014296    AY075433    GBBM01005632    JAC29786.1    DS235862    EEB19270.1    AAZX01005267    LJIJ01000088    ODN03051.1    NNAY01001139    OXU25013.1    CH954178    EDV52623.1   
Pfam
PF01597   GCV_H
Interpro
IPR011053   Single_hybrid_motif        + More
IPR017453   GCV_H_sub       
IPR002930   GCV_H       
IPR033753   GCV_H/Fam206       
IPR003016   2-oxoA_DH_lipoyl-BS       
IPR000089   Biotin_lipoyl       
SUPFAM
SSF51230   SSF51230       
PDB
2EDG     E-value=5.70235e-36,     Score=373

Ontologies

Topology

Subcellular location
Mitochondrion  
Length:
167
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.00055
Exp number, first 60 AAs:
0.00055
Total prob of N-in:
0.12792
outside
1  -  167
 
 

Population Genetic Test Statistics

Pi
14.463874
Theta
15.585574
Tajima's D
-0.884854
CLR
0.695412
CSRT
0.16079196040198
Interpretation
Uncertain
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