Gene

KWMTBOMO06871

Pre Gene Modal

BGIBMGA012072

Annotation

Mucolipin-3_[Operophtera_brumata]

Location

Bomo_Chr11(+):18057736-18059752      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.727

CDS

ATGGATGAAATCATGCATGCCCCTGATGATACTACCTGTTCTGAAGGCGAAGACGATCACAAAAAGGAAATTCGACCGAATGCCAACAATGAACAAGATTTTCCTCACCAATCGACTTCGTTCTCTCCGCCTACTCAAATGGAAGAAAAAATGCGTAGAAAACTGCAGTTTTTCTTTATGAATCCAATCGAGAAATGGAAAGCAAAGAGAAAATTTCCTTACAAATTTGTCGTGCAGGTAATCAAAATTGTACTTGTGACTTTTCAGCTATGTTTATTCGCTCATAACAGATACAATCACGTGAACTATACATGGGATAACAGAATCACATTCTCGCATCTATTTTTACTCGGCTGGGACTCTACACGTGAGATAAACGCATATCCACCGGGAGCAGGACCACTTGCTTTGTACAAAATCGATGAGTTCTACAATACATTAGACTATGCAGTTGCCGGTTATACTAATTTATCTAATGCGATAGGCCCATATTCGTACAATGATGAAAATAACTTTATGCCAGATCCTGTCTTTTGCCAGTACAACTATAAACAAGGCATTATTTATGGCTTTAATGAGAGCTACCAGTTTAACTCTGAAGTCTTTGAGACCTGTATAAATTTCACAATTAAAGATAATGAAGATTTCAAATCTGAAGCGTACATTAGAGATGCTGGATTGAACATCAGTTTCTCATCATTAGTTAGAGCAAAATTAATGTTTTCCATCAAAACCATCAACTTCAGGGCTGCCGGTCCCATAACTCCACCAGACTGTTACCGGTTTGATGTTGAAATAATATTTGACAATGAAGATCACGATGGACAAATGTCCTTGTTTCTGGAAGCAGAACCTCACAAGCTAGAATGTAAAGGCGACACAGCTTATGTGACGGATAATAAAATTGACCAAATACTCAGGAGTACTTTAAATATTTTAGTTATTTTGATTTGTGCAGCCTCGTTTGTGCTATGCAGCAGAGCACTCTACAGAGCACAGTTGCTAAAAGAATTAACAGTACAATTCTTTAGAAGACAATATGACAGAGACCTAAGCTTAGATGGAAGATTGGAGTTCTTGAATATTTGGTATATTATGATAATAATCAATGACCTTCTGATCATCATGGGATCAGCTATTAAGGAACAAATCGAACGAAATCAATTCACAAATGATCAGTGGAATGTTTGTTCACTGTTTTTAGGTACAGGAAATCTGCTCGTCTGGTTTGGAGTGCTAAGATACCTAGGTTTCTTCAAGACTTACAATGTTGTTATACTCACGTTGAAAAAAGCAGCTCCAAAAATATTCAGATTCTCAATTTGCGCTTTATTATTGTATGCAGGTTTCATGTTCTGTGGTTGGCTCATTTTGGGTCCCTATCATATGAAATTTAGATCACTAGCAACAACATCAGAATGTCTTTTCTCACTGATTAATGGAGATGACATGTTTGCAACCTTCTCCATCATGTCCAAGAAATCACCAATGCTATGGTGGTTTAGTCGTGTCTACCTATATTCGTTTATAAGTTTGTACATTTATGTTGTACTAAGTTTATTTATATCTGTTATTATGGATGCTTATGATACAATTAAACAATATTACAAAGATGGTTTTCCCAAAAGTGATTTGCAACAATTCATTGGTGAAACAAGGATTGAAGAGGTATCATCAGGATTGTACAGAGTTCATAGTTCATCATCCCTCAATGCAATAATGAACTCCCTTTTCTGTTGCAACATCTACAGAAGTGCATATTCAAAAATTGGGGGTAGAAGTTCAACAGTTAATTTAATGTACTTAATGAATATTTGTTTATTGTACAGATATGTACTTTTCAATAAATTAGAGAATGGCGAATTGATTAAATGA

Protein

MDEIMHAPDDTTCSEGEDDHKKEIRPNANNEQDFPHQSTSFSPPTQMEEKMRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFAHNRYNHVNYTWDNRITFSHLFLLGWDSTREINAYPPGAGPLALYKIDEFYNTLDYAVAGYTNLSNAIGPYSYNDENNFMPDPVFCQYNYKQGIIYGFNESYQFNSEVFETCINFTIKDNEDFKSEAYIRDAGLNISFSSLVRAKLMFSIKTINFRAAGPITPPDCYRFDVEIIFDNEDHDGQMSLFLEAEPHKLECKGDTAYVTDNKIDQILRSTLNILVILICAASFVLCSRALYRAQLLKELTVQFFRRQYDRDLSLDGRLEFLNIWYIMIIINDLLIIMGSAIKEQIERNQFTNDQWNVCSLFLGTGNLLVWFGVLRYLGFFKTYNVVILTLKKAAPKIFRFSICALLLYAGFMFCGWLILGPYHMKFRSLATTSECLFSLINGDDMFATFSIMSKKSPMLWWFSRVYLYSFISLYIYVVLSLFISVIMDAYDTIKQYYKDGFPKSDLQQFIGETRIEEVSSGLYRVHSSSSLNAIMNSLFCCNIYRSAYSKIGGRSSTVNLMYLMNICLLYRYVLFNKLENGELIK

Similarity

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Uniprot

H9JRB2   A0A2H1WSC3   A0A1E1WHP6   A0A2A4K7C3   A0A0L7KYP6   A0A194QV84   + More
A0A194Q9R9   A0A2Z5U781   A0A212EQ52   A0A2J7R4F3   A0A067R2P4   A0A2J7R4H3   A0A2J7R4I6   A0A2J7R4F7   D6WWW5   A0A1Y1L746   A0A088ACW6   A0A154NX64   A0A2A3ETX7   A0A310SY03   A0A195D3I4   A0A0L7QRA5   A0A182FG26   A0A182IX06   A0A2M4ADL2   A0A2M4AD56   W5JKF8   F4WWQ3   A0A2M4BGN8   A0A182QYK0   A0A182WIY9   A0A2M3ZGP5   A0A151X792   A0A182RB16   A0A195BLC8   A0A158NJ10   A0A182NHC0   A0A182XZB7   A0A2M3Z440   A0A182MPQ2   A0A182X6L3   A0A182U6M0   A0A1B0C8F8   A7UR58   A0A151JNC3   A0A1B6CB09   A0A1L8DDS5   E2BH61   Q17KW6   A0A182G9W3   A0A182GQQ2   E1ZWV2   A0A1B6DU29   A0A1B6DMH1   A0A0J7KSA6   A0A1B6C196   S6D9N2   A0A0C9R9Z5   E9IIV9   A0A384TJR2   A0A026WKL4   A0A1B6L400   A0A1B6M9T8   K7IR03   W8AWP8   T1PBL3   A0A1B6GAU7   A0A1B6HEJ6   A0A232EN81   A0A1I8NRX0   B0WVU8   A0A0L0C824   T1I059   A0A0K8TM30   A0A034VPR4   A0A0A1WXU1   A0A0K8TXY5   A0A023F518   A0A195FJG5   B4J3E0   A0A0M4EQB7   B4LDK6   A0A1Q3FBT3   B4KYW8   A0A1B0C6N2   A0A1Q3FDF2   A0A1Q3FBR0   A0A1A9W5X5   A0A1A9XJW7   Q29DE1   B4H9C3   A0A1J1IT15   A0A1J1IXI4   A0A0R1E888   A0A1A9ZDV9   B4N3M6   B4IIP8   A0A1B0GF70   A0A1A9UKP8   A0A3B0JVL6  

Pubmed

19121390    26227816    26354079    22118469    24845553    18362917    + More
19820115    28004739    20920257    23761445    21719571    21347285    25244985    12364791    14747013    17210077    20798317    17510324    26483478    23938757    21282665    24508170    30249741    20075255    24495485    25315136    28648823    26108605    26369729    25348373    25830018    25474469    17994087    15632085    17550304   

EMBL

BABH01016087    ODYU01010693    SOQ55970.1    GDQN01004566    JAT86488.1    NWSH01000052    + More
PCG80175.1    JTDY01004240    KOB68403.1    KQ461185    KPJ07466.1    KQ459252    KPJ02154.1    AP017502    BBB06793.1    AGBW02013309    OWR43618.1    NEVH01007419    PNF35721.1    KK852750    KDR17190.1    PNF35727.1    PNF35726.1    PNF35724.1    KQ971361    EFA09175.1    GEZM01064807    JAV68638.1    KQ434777    KZC04152.1    KZ288185    PBC34954.1    KQ759841    OAD62624.1    KQ976885    KYN07463.1    KQ414782    KOC61158.1    GGFK01005491    MBW38812.1    GGFK01005388    MBW38709.1    ADMH02001258    ETN63365.1    GL888412    EGI61375.1    GGFJ01003085    MBW52226.1    AXCN02000895    GGFM01006975    MBW27726.1    KQ982454    KYQ56180.1    KQ976453    KYM85515.1    ADTU01017350    ADTU01017351    GGFM01002467    MBW23218.1    AXCM01000589    AJWK01000543    AAAB01008807    EDO64504.1    KQ978889    KYN27662.1    GEDC01030678    GEDC01026620    GEDC01005880    GEDC01002170    JAS06620.1    JAS10678.1    JAS31418.1    JAS35128.1    GFDF01009557    JAV04527.1    GL448268    EFN84982.1    CH477221    EAT47288.1    JXUM01049861    KQ561624    KXJ77966.1    JXUM01015881    KQ560442    KXJ82386.1    GL434905    EFN74349.1    GEDC01008117    JAS29181.1    GEDC01010424    JAS26874.1    LBMM01003811    KMQ93109.1    GEDC01030005    JAS07293.1    HF586479    CCQ71383.1    GBYB01006334    GBYB01013234    JAG76101.1    JAG83001.1    GL763562    EFZ19447.1    KX249700    AOR81477.1    KK107163    QOIP01000002    EZA56523.1    RLU25816.1    GEBQ01021505    JAT18472.1    GEBQ01007289    JAT32688.1    GAMC01016048    JAB90507.1    KA646156    AFP60785.1    GECZ01010205    JAS59564.1    GECU01034559    JAS73147.1    NNAY01003212    OXU19782.1    DS232132    EDS35780.1    JRES01000760    KNC28588.1    ACPB03011941    GDAI01002613    JAI14990.1    GAKP01015399    GAKP01015397    JAC43553.1    GBXI01010418    JAD03874.1    GDHF01032990    GDHF01027057    JAI19324.1    JAI25257.1    GBBI01002583    JAC16129.1    KQ981523    KYN40134.1    CH916366    EDV97239.1    CP012525    ALC44442.1    CH940647    EDW69967.1    GFDL01010000    JAV25045.1    CH933809    EDW18860.1    JXJN01026843    GFDL01009472    JAV25573.1    GFDL01010031    JAV25014.1    CH379070    EAL30473.1    CH479227    EDW35347.1    CVRI01000059    CRL03256.1    CRL03257.1    CH891861    KRK05321.1    CH964095    EDW79231.1    CH480844    EDW49819.1    CCAG010012768    OUUW01000002    SPP77406.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053240    UP000053268    UP000007151    + More
UP000235965    UP000027135    UP000007266    UP000005203    UP000076502    UP000242457    UP000078542    UP000053825    UP000069272    UP000075880    UP000000673    UP000007755    UP000075886    UP000075920    UP000075809    UP000075900    UP000078540    UP000005205    UP000075884    UP000076408    UP000075883    UP000076407    UP000075902    UP000092461    UP000007062    UP000078492    UP000008237    UP000008820    UP000069940    UP000249989    UP000000311    UP000036403    UP000053097    UP000279307    UP000002358    UP000095301    UP000215335    UP000095300    UP000002320    UP000037069    UP000015103    UP000078541    UP000001070    UP000092553    UP000008792    UP000009192    UP000092460    UP000091820    UP000092443    UP000001819    UP000008744    UP000183832    UP000002282    UP000092445    UP000007798    UP000001292    UP000092444    UP000078200    UP000268350   

PRIDE

H9JRB2   

Pfam

PF08016   PKD_channel        + More
PF13426   PAS_9
PF16540   MKLP1_Arf_bdg
PF00160   Pro_isomerase
PF00225   Kinesin
PF00520   Ion_trans
PF02932   Neur_chan_memb
PF02931   Neur_chan_LBD
PF00027   cNMP_binding

Interpro

IPR013122   PKD1_2_channel        + More
IPR039031   Mucolipin       
IPR000014   PAS       
IPR027359   Volt_channel_dom_sf       
IPR006029   Neurotrans-gated_channel_TM       
IPR029000   Cyclophilin-like_dom_sf       
IPR030172   KCNH6       
IPR020892   Cyclophilin-type_PPIase_CS       
IPR000595   cNMP-bd_dom       
IPR006202   Neur_chan_lig-bd       
IPR038105   Kif23_Arf-bd_sf       
IPR002130   Cyclophilin-type_PPIase_dom       
IPR036734   Neur_chan_lig-bd_sf       
IPR032384   Kif23_Arf-bd       
IPR005821   Ion_trans_dom       
IPR036719   Neuro-gated_channel_TM_sf       
IPR027417   P-loop_NTPase       
IPR014710   RmlC-like_jellyroll       
IPR019821   Kinesin_motor_CS       
IPR018490   cNMP-bd-like       
IPR018000   Neurotransmitter_ion_chnl_CS       
IPR035965   PAS-like_dom_sf       
IPR036961   Kinesin_motor_dom_sf       
IPR001752   Kinesin_motor_dom       
IPR003967   K_chnl_volt-dep_ERG       
IPR003938   K_chnl_volt-dep_EAG/ELK/ERG       

SUPFAM

SSF52540   SSF52540        + More
SSF50891   SSF50891       
SSF51206   SSF51206       
SSF55785   SSF55785       
SSF63712   SSF63712       
SSF90112   SSF90112       

Gene 3D

1.20.120.350     2.40.100.10     2.60.120.10     3.40.50.12000     3.40.850.10    

CDD

cd00038  CAP_ED
cd00130  PAS

ProteinModelPortal

H9JRB2   A0A2H1WSC3   A0A1E1WHP6   A0A2A4K7C3   A0A0L7KYP6   A0A194QV84   + More
A0A194Q9R9   A0A2Z5U781   A0A212EQ52   A0A2J7R4F3   A0A067R2P4   A0A2J7R4H3   A0A2J7R4I6   A0A2J7R4F7   D6WWW5   A0A1Y1L746   A0A088ACW6   A0A154NX64   A0A2A3ETX7   A0A310SY03   A0A195D3I4   A0A0L7QRA5   A0A182FG26   A0A182IX06   A0A2M4ADL2   A0A2M4AD56   W5JKF8   F4WWQ3   A0A2M4BGN8   A0A182QYK0   A0A182WIY9   A0A2M3ZGP5   A0A151X792   A0A182RB16   A0A195BLC8   A0A158NJ10   A0A182NHC0   A0A182XZB7   A0A2M3Z440   A0A182MPQ2   A0A182X6L3   A0A182U6M0   A0A1B0C8F8   A7UR58   A0A151JNC3   A0A1B6CB09   A0A1L8DDS5   E2BH61   Q17KW6   A0A182G9W3   A0A182GQQ2   E1ZWV2   A0A1B6DU29   A0A1B6DMH1   A0A0J7KSA6   A0A1B6C196   S6D9N2   A0A0C9R9Z5   E9IIV9   A0A384TJR2   A0A026WKL4   A0A1B6L400   A0A1B6M9T8   K7IR03   W8AWP8   T1PBL3   A0A1B6GAU7   A0A1B6HEJ6   A0A232EN81   A0A1I8NRX0   B0WVU8   A0A0L0C824   T1I059   A0A0K8TM30   A0A034VPR4   A0A0A1WXU1   A0A0K8TXY5   A0A023F518   A0A195FJG5   B4J3E0   A0A0M4EQB7   B4LDK6   A0A1Q3FBT3   B4KYW8   A0A1B0C6N2   A0A1Q3FDF2   A0A1Q3FBR0   A0A1A9W5X5   A0A1A9XJW7   Q29DE1   B4H9C3   A0A1J1IT15   A0A1J1IXI4   A0A0R1E888   A0A1A9ZDV9   B4N3M6   B4IIP8   A0A1B0GF70   A0A1A9UKP8   A0A3B0JVL6  

PDB

6AYG     E-value=4.70845e-110,     Score=1019

KEGG

101738635    K04994 mucolipin 3 | (RefSeq) mucolipin-3-like

GO

GO:0016021   GO:0005261   GO:0005765   GO:0005886   GO:0072345   GO:0008017   GO:0003777   GO:0006457   GO:0005524   GO:0000915   GO:0005623   GO:0072383   GO:0005230   GO:0003755   GO:0005249   GO:0034765  

PANTHER

PTHR12127   PTHR10217:SF468  

Length:

624

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

148.06867

Exp number, first 60 AAs:

0

Total prob of N-in:

0.08504

outside

1  -  75

TMhelix

76  -  98

inside

99  -  307

TMhelix

308  -  330

outside

331  -  358

TMhelix

359  -  381

inside

382  -  393

TMhelix

394  -  416

outside

417  -  435

TMhelix

436  -  458

inside

459  -  503

TMhelix

504  -  526

outside

527  -  596

TMhelix

597  -  614

inside

615  -  624

 

 

Pi

3.772965

Theta

20.899828

Tajima's D

-2.014434

CLR

32.981193

CSRT

0.0127493625318734

Interpretation

Uncertain