Gene

KWMTBOMO06870  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012083

Annotation

PREDICTED:_ancient_ubiquitous_protein_1-like_[Bombyx_mori]

Location

Bomo_Chr11(-):18048767-18056955      View in EpiBrowser

Full name

Ancient ubiquitous protein 1      

Location in the cell

PlasmaMembrane   Reliability : 3.681

CDS

ATGGCTCTTGCGGCAGAAAAGTTAATCAACAAAGAGAGATTCAATGGAGAAAATGCATTGCAATTTTTACTGTATTTACCAATTGGAGTTATTCTGATGGTGATCAGAATATTCCTGGGTGTGATATTATGGATTGCATCAATTATATTGCCCAACAAATGGGCAGTCAGTCACATGTTAACTACTTTGGCTTGTTGGACTTTTGGTGTCTATGTGAAGCTCAAAGGACAAAGAGACCCAAGATGTAGTGTGTTGGTTGCTAACTATGTGACATGTTTCGATTCTCTTGCAGCTGCACATGTCTTTGGTACCATAAGTTTGAAAAGATGGAAGTTGCCACCATTTTTCGCATCGACGTTGGGTATAAAGAACGCCTCACAATTTTCTAAAAAGCAACATTTCTCTGAGGTGCCAACAAAGCCTGTGTTGATACAACCAGAAAGTGGACCCACGAACGGTAAAGCGGTGTTACGTTTCACAGATTGGCCATTCCAGATTAAAAGCAATGTGCAGCCGGTCGCCATCACCGTGGAGCGCGCCTTCACGCGTGCGACGGTGCAGCGGCGCCAGTACAGCGCGCGCTTCCCGTGGCGCGACGCGGCGTGGTTCCTGCTGTCGCCCGCCACCGTGTACACGCTGCACGCGCTGCCGCCGCTGCGCTGGGACGCGGGGGACGTCGGGGACCGCTGCCGGGCCGCCGTCGCAGAGGCGCTGCAGGTGGAAGTGTCGGAGCTGACGTGGGACGAGTTGTTCGCGGGGAGGCGTGTCCGGGCCGTCGCCGACCGCGCCGCCCCGCTCGTGCGCCTCGGGAACCAGGTCAAGGAAGTGTTGCCAGCCGTCCCACTCAAAACTATCCTCCAGGATTTAGGTGTGTTTCGGCGCAGAATCGGCGTGGACACCCTCGCCGAGTGTTGCCATGTTTTTTTTTTTTTAGAGTCCTTTGATGGGTGGACGAGCTCACAGCCCACCTGGTGTTAA

Protein

MALAAEKLINKERFNGENALQFLLYLPIGVILMVIRIFLGVILWIASIILPNKWAVSHMLTTLACWTFGVYVKLKGQRDPRCSVLVANYVTCFDSLAAAHVFGTISLKRWKLPPFFASTLGIKNASQFSKKQHFSEVPTKPVLIQPESGPTNGKAVLRFTDWPFQIKSNVQPVAITVERAFTRATVQRRQYSARFPWRDAAWFLLSPATVYTLHALPPLRWDAGDVGDRCRAAVAEALQVEVSELTWDELFAGRRVRAVADRAAPLVRLGNQVKEVLPAVPLKTILQDLGVFRRRIGVDTLAECCHVFFFLESFDGWTSSQPTWC

Description

May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.

Similarity

Belongs to the AUP1 family.

Keywords

Endoplasmic reticulum   Membrane   Transmembrane   Transmembrane helix   Ubl conjugation pathway  

Feature

chain  Ancient ubiquitous protein 1

Uniprot

A0A2A4K845   A0A3S2M9U1   A0A212F821   A0A194QAY6   A0A194QR67   D6WWW6   + More
A0A1S3H109   W4ZDZ0   A0A2J7QR91   A0A1W7RAY6   A0A1Y1N0H5   A0A1Y1N0D0   A0A069DU96   A0A2J7QR90   A0A224XQZ4   A0A023FAJ5   R4FME3   A0A0P4W545   A0A3B5BN49   A0A0V0G4S0   M3Y9Q9   A0A183G5H3   A0A3P8BLE0   A0A2A3E6B4   B1H1N7   A0A158NHT8   A0A088AAK4   A0A1L8HK24   C3Y446   A0A0J7NCH3   E1ZXZ9   A0A1W4ZMB1   A0A3B4YNB6   A0A3B4UHM2   A0A3Q3G3J2   A0A3Q1ES39   M1EFX7   A0A0T6B5Y3   A0A3Q3JQE0   A0A195BVU4   A0A1A8CC12   A0A1B6KFF7   N6UAT9   A0A1B6G5A6   A0A195DFA4   A0A0K0EYF5   A0A2I4BDP7   A0A2A2K7Z0   A0A2A2K806   A0A1A7ZYV6   A0A3P9N8C1   F4WCN5   A0A3B3CBZ7   A0A0N5C939   A0A3Q1CLM2   A0A158QN13   A0A2A2K8C8   W6NGS0   A0A0S7HJM6   A0A1A8H6Q1   A0A0L8H3Y5   A0A1A8MGD7   A0A146MZT2   A0A1S3GPA0   A0A2A2K7Y7   A0A0P7WQI8   A0A0K0E8W8   A0A3P8SFY4   A0A151WY16   A0A1S3GMI9   A0A1A7Z196   E2BUN6   A0A090LA34   A0A3Q3SDU4   A0A315VJZ4   A0A226MFR1   A0A1A8G5G4   A0A1A8PKL4   M4AX05   A0A1S3GQ43   A0A1A8EGW0   A0A1A8S2A2   A0A146QHR3   A0A1A8B639   A0A2U9C8M4   A0A016WQX4   H2T0T8   A0A2U9CA20   A0A1W4WMY8   A0A226NTF8   A0A195CVE3   A0A0F8AFJ3   A0A1A8KZ50   A0A195ET26   A0A2U9C7C4   A0A0N4ZYH6  

Pubmed

22118469    26354079    18362917    19820115    28004739    26334808    + More
25474469    27129103    21347285    27762356    18563158    20798317    23236062    23537049    21719571    29451363    29703783    23542700    25730766    21551351    24621616    25835551   

EMBL

NWSH01000052    PCG80176.1    RSAL01000006    RVE54334.1    AGBW02009812    OWR49859.1    + More
KQ459252    KPJ02155.1    KQ461185    KPJ07465.1    KQ971361    EFA08762.1    AAGJ04129253    NEVH01011922    PNF31095.1    GFAH01000076    JAV48313.1    GEZM01016146    JAV91364.1    GEZM01016147    JAV91362.1    GBGD01001612    JAC87277.1    PNF31096.1    GFTR01006027    JAW10399.1    GBBI01000774    JAC17938.1    ACPB03009974    GAHY01001043    JAA76467.1    GDKW01000097    JAI56498.1    GECL01003066    JAP03058.1    AEYP01010579    UZAH01029663    VDP07275.1    KZ288374    PBC26709.1    BC129705    BC160678    ADTU01001748    CM004467    OCT96447.1    GG666484    EEN65072.1    LBMM01006854    KMQ90275.1    GL435158    EFN73939.1    JP006246    AER94843.1    LJIG01009574    KRT82808.1    KQ976398    KYM92702.1    HADZ01012662    SBP76603.1    GEBQ01029806    JAT10171.1    APGK01042192    KB741002    KB631903    ENN75747.1    ERL87036.1    GECZ01012276    JAS57493.1    KQ980905    KYN11522.1    LIAE01009369    PAV70041.1    PAV70040.1    HADY01009499    SBP47984.1    GL888070    EGI68215.1    UZAF01017095    VDO37860.1    PAV70039.1    CAVP010059635    CDL95955.1    GBYX01440132    JAO41231.1    HAEC01010912    SBQ79128.1    KQ419338    KOF83912.1    HAEF01014821    SBR55980.1    GCES01161149    JAQ25173.1    PAV70038.1    JARO02007574    KPP63794.1    KQ982662    KYQ52647.1    HADX01014430    SBP36662.1    GL450732    EFN80589.1    LN609528    CEF64370.1    NHOQ01001578    PWA23482.1    MCFN01000982    OXB54121.1    HAEB01019811    SBQ66338.1    HAEF01002135    HAEG01008467    SBR81945.1    HADZ01005287    HAEA01015844    SBQ44325.1    HAEI01004260    HAEH01021019    SBS11683.1    GCES01130573    JAQ55749.1    HADY01023465    HAEJ01010811    SBP61950.1    CP026255    AWP12470.1    JARK01000147    EYC42001.1    AWP12469.1    AWGT02000675    OXB71065.1    KQ977259    KYN04605.1    KQ042260    KKF16702.1    HAED01001599    HAEE01016879    SBR36929.1    KQ981979    KYN31311.1    AWP12471.1   

Proteomes

UP000218220    UP000283053    UP000007151    UP000053268    UP000053240    UP000007266    + More
UP000085678    UP000007110    UP000235965    UP000015103    UP000261400    UP000000715    UP000050761    UP000242457    UP000005205    UP000005203    UP000186698    UP000001554    UP000036403    UP000000311    UP000192224    UP000261360    UP000261420    UP000264800    UP000257200    UP000261600    UP000078540    UP000019118    UP000030742    UP000078492    UP000035680    UP000192220    UP000218231    UP000242638    UP000007755    UP000261560    UP000046392    UP000257160    UP000038042    UP000268014    UP000025227    UP000053454    UP000265000    UP000081671    UP000034805    UP000035681    UP000265080    UP000075809    UP000008237    UP000035682    UP000261640    UP000198323    UP000002852    UP000246464    UP000024635    UP000005226    UP000192223    UP000198419    UP000078542    UP000078541    UP000038045   

Pfam

PF02845   CUE

Interpro

IPR003892   CUE        + More
IPR002123   Plipid/glycerol_acylTrfase       
IPR006155   Josephin       

ProteinModelPortal

A0A2A4K845   A0A3S2M9U1   A0A212F821   A0A194QAY6   A0A194QR67   D6WWW6   + More
A0A1S3H109   W4ZDZ0   A0A2J7QR91   A0A1W7RAY6   A0A1Y1N0H5   A0A1Y1N0D0   A0A069DU96   A0A2J7QR90   A0A224XQZ4   A0A023FAJ5   R4FME3   A0A0P4W545   A0A3B5BN49   A0A0V0G4S0   M3Y9Q9   A0A183G5H3   A0A3P8BLE0   A0A2A3E6B4   B1H1N7   A0A158NHT8   A0A088AAK4   A0A1L8HK24   C3Y446   A0A0J7NCH3   E1ZXZ9   A0A1W4ZMB1   A0A3B4YNB6   A0A3B4UHM2   A0A3Q3G3J2   A0A3Q1ES39   M1EFX7   A0A0T6B5Y3   A0A3Q3JQE0   A0A195BVU4   A0A1A8CC12   A0A1B6KFF7   N6UAT9   A0A1B6G5A6   A0A195DFA4   A0A0K0EYF5   A0A2I4BDP7   A0A2A2K7Z0   A0A2A2K806   A0A1A7ZYV6   A0A3P9N8C1   F4WCN5   A0A3B3CBZ7   A0A0N5C939   A0A3Q1CLM2   A0A158QN13   A0A2A2K8C8   W6NGS0   A0A0S7HJM6   A0A1A8H6Q1   A0A0L8H3Y5   A0A1A8MGD7   A0A146MZT2   A0A1S3GPA0   A0A2A2K7Y7   A0A0P7WQI8   A0A0K0E8W8   A0A3P8SFY4   A0A151WY16   A0A1S3GMI9   A0A1A7Z196   E2BUN6   A0A090LA34   A0A3Q3SDU4   A0A315VJZ4   A0A226MFR1   A0A1A8G5G4   A0A1A8PKL4   M4AX05   A0A1S3GQ43   A0A1A8EGW0   A0A1A8S2A2   A0A146QHR3   A0A1A8B639   A0A2U9C8M4   A0A016WQX4   H2T0T8   A0A2U9CA20   A0A1W4WMY8   A0A226NTF8   A0A195CVE3   A0A0F8AFJ3   A0A1A8KZ50   A0A195ET26   A0A2U9C7C4   A0A0N4ZYH6  

KEGG

101737172    K19716 ancient ubiquitous protein 1 | (RefSeq) ancient ubiquitous protein 1-like

GO

GO:0016021   GO:0030176   GO:0043130   GO:0000839   GO:0030433   GO:0097027   GO:0016020   GO:0016746   GO:0030970   GO:0005737   GO:0005789   GO:0016579   GO:0004843  

Subcellular location

Endoplasmic reticulum membrane  

Length:

325

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

64.8835100000002

Exp number, first 60 AAs:

30.77496

Total prob of N-in:

0.98947

POSSIBLE N-term signal

sequence

inside

1  -  21

TMhelix

22  -  44

outside

45  -  53

TMhelix

54  -  72

inside

73  -  84

TMhelix

85  -  107

outside

108  -  325

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

33.892833

CSRT

0

Interpretation

Uncertain