Gene

KWMTBOMO06855

Pre Gene Modal

BGIBMGA012088

Annotation

cysteine_sulfinic_acid_decarboxylase_[Bombyx_mori]

Location

Bomo_Chr11(-):17663541-17671896      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 3.516

CDS

ATGCCTGCCGATTCAGATCTTATAGTCGCCGAGAGAGAGGACTTGGGCATTGATAGAACCCTCTACAAGTCACTCTCAGAGAGATCTAAGCATGAAGATTTTATCAGGCGGGCAGTGGATTTGCTGGTTGAAAGGGTAGTGTTCGGAAGGTCCCTGAGGACTTCTAAGGTGGTGGAATGGGCTGTACCGTCGGAGATCAAGAAAGCCATCGACTTGAAACCTAGAGATGGGCCCATTTCTCACGATGAACTTTTGGGACTCATGGCTGATGTGGCCCGATATTCCGTGAACACAGCCCATCCGTATTTCGTAAATCAGTTGTATTCATCCGTGGACCCGTATGGCTTGGTCGGACAATGGCTGACAGATGCCCTCAATCCAAGCGTGTATACCTATGAAGTTGCACCAGTTTTTACTCTAATGGAGGAAGAAGTGCTAAAGGAGATGAGGGTACTCGTTGGATGGAAAGATGGAGAAGGTGATGGTATATTTTGCCCGGGTGGTTCCATTGCCAACGGTTATGCCATCAGCTGCGCTAGATTCCATTTCTATCCTGAAATAAAGACAAAAGGCGTATACGCTGTACCGAAACTGACGCTATACACATCGGAGCTAGCACATTACTCGACGAAAAAATTGGCCGCATTCATGGGGATAGGAGATGAAAACTGCGTTTTAATAAAAACCGATAAATACGGTAAAATCGATGTTGAAGATTTAGAGGCTAAAATTGTGGAGGGCATCGAGGAGGGCGCTGCTCCATTCCTCGTCACAGCCACCGCTGGTACCACAGTCTTTGGTGCTTTCGACCCATTAGTCCCCATAGCGGCGCTCTGCAAGAAATACAATCTCTGGCTTCATGTTGACGCCGCTTGGGGTGGTGGAGCCTTAATGTCGAAGAAACATAGGCATCTGTTGAATGGAATTGAATTGGCGGATTCAGTCACGTGGAATCCCCACAAGCTACTGGCTGCTCCTCAACAATGCTCCACGTTCCTAATTAGACACAAGAACGTTCTCAAGGAAGGACACTCGTGCAATGCGAAGTACCTCTTCCAGAAGGACAAATTCTACGACACATCATACGATACGGGGGACAAACATATCCAGTGCGGTCGACGGGCGGATGTCCTCAAATTCTGGTTCATGTGGAAGGCCAAAGGCTCGGACGGCTTCGAGAACCACATCGATACGCTATTCGATAACGCGCGCTTCTTCTTGGAACAGATTCGTAATCGGGAAGGCTTCGAATTGGTCATTGAAAAACCGGAATGCACGAACATAATGTTCTGGTACGTACCGCGTTGCCTTCGCGGCTGCGAAAACGAGTCGGACTACAGAGAAAGGCTCCACAAGGTTGCCCCTAAAATTAAAGAATTAATGATAAAGGAAGGAAGTATGATGGTAACTTATCAGCCTCAAGGAGATCTTGTGAATTTCTTCCGTATCGTGTTCCAAAATTCGGCCCTCGATCACAAGGATATGATATATTTCGTAAACGAATTCGAAAGGCTCGGCAGAGACATATTAGTCTAA

Protein

MPADSDLIVAEREDLGIDRTLYKSLSERSKHEDFIRRAVDLLVERVVFGRSLRTSKVVEWAVPSEIKKAIDLKPRDGPISHDELLGLMADVARYSVNTAHPYFVNQLYSSVDPYGLVGQWLTDALNPSVYTYEVAPVFTLMEEEVLKEMRVLVGWKDGEGDGIFCPGGSIANGYAISCARFHFYPEIKTKGVYAVPKLTLYTSELAHYSTKKLAAFMGIGDENCVLIKTDKYGKIDVEDLEAKIVEGIEEGAAPFLVTATAGTTVFGAFDPLVPIAALCKKYNLWLHVDAAWGGGALMSKKHRHLLNGIELADSVTWNPHKLLAAPQQCSTFLIRHKNVLKEGHSCNAKYLFQKDKFYDTSYDTGDKHIQCGRRADVLKFWFMWKAKGSDGFENHIDTLFDNARFFLEQIRNREGFELVIEKPECTNIMFWYVPRCLRGCENESDYRERLHKVAPKIKELMIKEGSMMVTYQPQGDLVNFFRIVFQNSALDHKDMIYFVNEFERLGRDILV

Cofactor

pyridoxal 5'-phosphate

Similarity

Belongs to the group II decarboxylase family.

Uniprot

H9JRC8   A0A0C5QEV9   A0A0L7LFT8   A0A2H1WRM9   A0A194PEG0   D4AH66   + More
A0A194R3E1   A0A3S2TSR1   A0A0G3VGT7   A0A2A4JAM0   G8FGR7   G4XH89   A0A212EPV4   A0A2J7PB96   A0A067QKQ9   A9YVA8   A7U8C7   A0A1B6GV38   A0A2H8TVD8   A0A182XNP4   A0A182LMV3   A0A182I7A3   Q7PWN7   A0A182UR97   A0A182QH49   J9KAH8   A0A182P8A6   A0A182Y0A8   A0A182J8I3   A0A182LVI3   A0A182VUD2   A0A182RSJ2   A0A084VL13   A0A182MZ80   A0A1S4FGS8   Q171S0   A0A336MJ76   A0A2S2Q2F2   A0A1Y1MWE9   A0A0T6BCB4   A0A1W4WSF2   A0A1Q3FT64   A0A1Q3FT96   U4UTD4   A0A154PAD6   N6TKV9   B0WRQ9   A0A0L0CK42   B4JCX3   K7IY18   A0A3B0K3M2   A0A0J9R2X0   B3MN27   B4HXA1   A0A1Q3FSS4   A0A1A9YJW1   A0A0A9XUT1   B4Q567   A0A0L7RAZ6   B4KIX9   A0A1W4V741   A0A1B0BT94   A0A023F549   A0A0M4E5T9   A0A3B0KBV2   A0A1J1HN78   Q24062   A0A1L8DZC2   A0A1I8Q1Y9   A0A1A9UYR8   B4GX04   B4P3Q4   A0A0N0BFM6   B4N0X5   X2J8B3   B3NAD2   B4M8L3   Q29K73   A0A087ZNY3   A0A1A9Z445   T1I1H2   A0A1I8ME86   A0A2A3E1X6   W8AVS4   A0A1S3D4P7   A0A1A9WXD3   A0A0C9R8F6   A0A0K8VN41   A0A1B0G692   A0A034WAD5   A0A182F2K1   A0A232FDU5   A0A0A1X1S4   A0A195CYF4   A0A026WF04   A0A151JW08   E1ZV07   A0A3L8DKF1   A0A151JQB3   F4WHT2  

Pubmed

19121390    26227816    26354079    22234245    22118469    24845553    + More
19366687    20966253    12364791    14747013    17210077    25244985    24438588    17510324    28004739    23537049    26108605    17994087    20075255    22936249    25401762    25474469    8376987    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    15632085    25315136    24495485    25348373    28648823    25830018    24508170    20798317    30249741    21719571   

EMBL

BABH01016128    KM523624    AJQ30182.1    KM523625    AJQ30183.1    JTDY01001309    + More
KOB74239.1    ODYU01010161    SOQ55084.1    KQ459606    KPI91741.1    AB503723    BAI87832.1    KQ460779    KPJ12323.1    RSAL01000007    RVE54119.1    KP657641    AKL78866.1    NWSH01002373    PCG68443.1    JN003850    AEQ77286.1    JF811444    AEP43793.1    AGBW02013361    OWR43523.1    NEVH01027131    PNF13607.1    KK853239    KDR09499.1    EU302526    ABX89951.1    EU019709    ABU25221.1    GECZ01003514    JAS66255.1    GFXV01006382    MBW18187.1    APCN01003374    AAAB01008984    EAA14875.5    AXCN02002069    ABLF02018654    AXCM01000345    ATLV01014395    KE524970    KFB38657.1    CH477447    EAT40747.1    UFQS01001093    UFQT01001093    SSX08972.1    SSX28883.1    GGMS01002618    MBY71821.1    GEZM01020016    JAV89458.1    LJIG01001997    KRT84943.1    GFDL01004403    JAV30642.1    GFDL01004402    JAV30643.1    KB632355    ERL93380.1    KQ434857    KZC08803.1    APGK01033004    APGK01033005    KB740860    ENN78563.1    DS232058    EDS33463.1    JRES01000300    KNC32620.1    CH916368    EDW03212.1    OUUW01000006    SPP82540.1    CM002910    KMY90164.1    CH902620    EDV32005.1    CH480818    EDW51681.1    GFDL01004401    JAV30644.1    GBHO01019032    GBRD01000590    JAG24572.1    JAG65231.1    CM000361    EDX04973.1    KQ414618    KOC67911.1    CH933807    EDW13492.1    JXJN01020065    GBBI01002528    JAC16184.1    CP012523    ALC39546.1    SPP82541.1    CVRI01000010    CRK88836.1    U01239    AE014134    AY069752    AAC46466.1    AAF53337.1    AAL39897.1    AFH03699.1    GFDF01002254    JAV11830.1    CH479195    EDW27331.1    CM000157    EDW88355.1    KQ435798    KOX73314.1    CH963920    EDW77738.1    AHN54424.1    CH954177    EDV58634.1    CH940654    EDW57539.1    CH379061    EAL33304.2    ACPB03006877    KZ288443    PBC25695.1    GAMC01017728    GAMC01017727    GAMC01017726    GAMC01017725    GAMC01017724    GAMC01017723    JAB88828.1    GBYB01008619    GBYB01009157    JAG78386.1    JAG78924.1    GDHF01012017    JAI40297.1    CCAG010006778    GAKP01007298    JAC51654.1    NNAY01000405    OXU28629.1    GBXI01009220    JAD05072.1    KQ977171    KYN05174.1    KK107238    EZA54612.1    KQ981688    KYN37926.1    GL434335    EFN75005.1    QOIP01000007    RLU20663.1    KQ978684    KYN29300.1    GL888167    EGI66289.1   

Proteomes

UP000005204    UP000037510    UP000053268    UP000053240    UP000283053    UP000218220    + More
UP000007151    UP000235965    UP000027135    UP000076407    UP000075882    UP000075840    UP000007062    UP000075903    UP000075886    UP000007819    UP000075885    UP000076408    UP000075880    UP000075883    UP000075920    UP000075900    UP000030765    UP000075884    UP000008820    UP000192223    UP000030742    UP000076502    UP000019118    UP000002320    UP000037069    UP000001070    UP000002358    UP000268350    UP000007801    UP000001292    UP000092443    UP000000304    UP000053825    UP000009192    UP000192221    UP000092460    UP000092553    UP000183832    UP000000803    UP000095300    UP000078200    UP000008744    UP000002282    UP000053105    UP000007798    UP000008711    UP000008792    UP000001819    UP000005203    UP000092445    UP000015103    UP000095301    UP000242457    UP000079169    UP000091820    UP000092444    UP000069272    UP000215335    UP000078542    UP000053097    UP000078541    UP000000311    UP000279307    UP000078492    UP000007755   

PRIDE

H9JRC8    Q24062    X2J8B3   

Pfam

PF00282   Pyridoxal_deC        + More
PF00621   RhoGEF
PF00617   RasGEF
PF00125   Histone
PF00169   PH
PF00618   RasGEF_N
PF16213   DCB
PF12783   Sec7_N
PF01369   Sec7
PF09324   DUF1981

Interpro

IPR015424   PyrdxlP-dep_Trfase        + More
IPR002129   PyrdxlP-dep_de-COase       
IPR015421   PyrdxlP-dep_Trfase_major       
IPR001895   RASGEF_cat_dom       
IPR035899   DBL_dom_sf       
IPR002119   Histone_H2A       
IPR008937   Ras-like_GEF       
IPR023578   Ras_GEF_dom_sf       
IPR001849   PH_domain       
IPR000219   DH-domain       
IPR009072   Histone-fold       
IPR019804   Ras_G-nucl-exch_fac_CS       
IPR007125   Histone_H2A/H2B/H3       
IPR011993   PH-like_dom_sf       
IPR000651   Ras-like_Gua-exchang_fac_N       
IPR032629   DCB_dom       
IPR015403   Sec7_C       
IPR000904   Sec7_dom       
IPR016024   ARM-type_fold       
IPR032691   Sec7_N       
IPR035999   Sec7_dom_sf       
IPR023394   Sec7_C_sf       
IPR015422   PyrdxlP-dep_Trfase_dom1       

SUPFAM

SSF53383   SSF53383        + More
SSF47113   SSF47113       
SSF48065   SSF48065       
SSF48366   SSF48366       
SSF48371   SSF48371       
SSF48425   SSF48425       

Gene 3D

3.40.640.10     1.10.20.10     1.20.900.10     2.30.29.30     1.10.1000.11     3.90.1150.10    

CDD

cd06224  REM
cd00160  RhoGEF
cd00155  RasGEF
cd00171  Sec7

ProteinModelPortal

H9JRC8   A0A0C5QEV9   A0A0L7LFT8   A0A2H1WRM9   A0A194PEG0   D4AH66   + More
A0A194R3E1   A0A3S2TSR1   A0A0G3VGT7   A0A2A4JAM0   G8FGR7   G4XH89   A0A212EPV4   A0A2J7PB96   A0A067QKQ9   A9YVA8   A7U8C7   A0A1B6GV38   A0A2H8TVD8   A0A182XNP4   A0A182LMV3   A0A182I7A3   Q7PWN7   A0A182UR97   A0A182QH49   J9KAH8   A0A182P8A6   A0A182Y0A8   A0A182J8I3   A0A182LVI3   A0A182VUD2   A0A182RSJ2   A0A084VL13   A0A182MZ80   A0A1S4FGS8   Q171S0   A0A336MJ76   A0A2S2Q2F2   A0A1Y1MWE9   A0A0T6BCB4   A0A1W4WSF2   A0A1Q3FT64   A0A1Q3FT96   U4UTD4   A0A154PAD6   N6TKV9   B0WRQ9   A0A0L0CK42   B4JCX3   K7IY18   A0A3B0K3M2   A0A0J9R2X0   B3MN27   B4HXA1   A0A1Q3FSS4   A0A1A9YJW1   A0A0A9XUT1   B4Q567   A0A0L7RAZ6   B4KIX9   A0A1W4V741   A0A1B0BT94   A0A023F549   A0A0M4E5T9   A0A3B0KBV2   A0A1J1HN78   Q24062   A0A1L8DZC2   A0A1I8Q1Y9   A0A1A9UYR8   B4GX04   B4P3Q4   A0A0N0BFM6   B4N0X5   X2J8B3   B3NAD2   B4M8L3   Q29K73   A0A087ZNY3   A0A1A9Z445   T1I1H2   A0A1I8ME86   A0A2A3E1X6   W8AVS4   A0A1S3D4P7   A0A1A9WXD3   A0A0C9R8F6   A0A0K8VN41   A0A1B0G692   A0A034WAD5   A0A182F2K1   A0A232FDU5   A0A0A1X1S4   A0A195CYF4   A0A026WF04   A0A151JW08   E1ZV07   A0A3L8DKF1   A0A151JQB3   F4WHT2  

PDB

2JIS     E-value=2.25691e-147,     Score=1340

KEGG

101739336    K01580 glutamate decarboxylase [EC:4.1.1.15] | (RefSeq) black; cysteine sulfinic acid decarboxylase

PATHWAY

00250    Alanine, aspartate and glutamate metabolism - Bombyx mori (domestic silkworm)
00410    beta-Alanine metabolism - Bombyx mori (domestic silkworm)
00430    Taurine and hypotaurine metabolism - Bombyx mori (domestic silkworm)
00650    Butanoate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0030170   GO:0019752   GO:0004068   GO:0016831   GO:0016829   GO:0004351   GO:0016021   GO:0007632   GO:0048066   GO:0019483   GO:0006212   GO:0035023   GO:0005089   GO:0046982   GO:0007264   GO:0005634   GO:0000786   GO:0003677   GO:0032012   GO:0005086   GO:0003824   GO:0004713   GO:0043565   GO:0016567   GO:0016020   GO:0006260  

PANTHER

PTHR23113  

Length:

511

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.07045

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00124

outside

1  -  511

 

 

Pi

4.098893

Theta

14.40652

Tajima's D

-1.79803

CLR

199.943654

CSRT

0.0256987150642468

Interpretation

Uncertain