Gene

KWMTBOMO06846

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr11(-):17417446-17422726      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.573 Nuclear   Reliability : 1.659

CDS

ATGGACGCTGTATTTGCGGAATTTCTCCGGCTTCGCTATCCAAAGCTCACTTCCGAGTTTCAGGCCTTCAAGGCCGATCACACTGCGAGCCCTCTCGTGGACTCCACCGAGCTCGCTGCTCCTGCGTCGCCTGTACCTGCGTGCAAAGCTTCTGCATCGAGCACCGCAGCCTCCGTCGTGCCTGCCGTTCCCGCGTCGCCTATACTGGCGAGTAAAACTGCTGCGTCGTCCGCCGTGGTCACCGTTCCAGCAGCGCGATCATCCGCGGCCTCCGTCGCGCCGTCCAAAACACCTACTCGTAGGTCACCTGCGCCCGCCTCCTCGTCCTCCGACTCTGACTCGGAGATGGAGGTCGACCTCGCTCCCGCCTCATCGACGGATGGATTCACCCTGGTGCAAAAGGGTAAGAAGCGTGCCGCGGAGTCTCGAGCTCCCGCGGCCGCTAAAATTAGCAAAGCCGCGAACGCGTCGCGCCCCCGCCCTCAGACTCCCGTTGCGCCTCCAGCCCGTGCCACTCCGTCGCCGCGTACGGTGGCACAAAATAAAGCCCAGACCCCTCCCCCGGTAATCCTTCAAGAGAAGGCAGCTTGGGAACGAGTTTCCCTGGCCCTTAAGGCCAAAAATATCAATTTTACGAATGCCCGTAACCTCGCGAACGGCATTCAAATTAAGGTTCGAACATCCGACGACCATAGGGCCCTCTCTTCTTACCTCCGTAAGGAGCGTATAAGTTTCCACACATATACGCTCCAGGAGGAGCGCGAACTCCGTGCCGTTATACGTGGCATCCCTAAAGAGTTGGATGCCGAGCTCGTCAAGGCCGACCTTCTCGAACAAGGCCTACCGGTTAACTCCGTACACCGCATGCACACAGGCCGCGGAAGGGAGCCATATAATATGGTTCTCGTCGCCCTCCAGCCTACCCCCGAGGTGCAGGAGACCCTACTTAAGCCCGCGCGCCGTGACCCTAAAATCGCGAACTATAACATGGTCAGGAACGACAGGCTCTCTGCTCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCACTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGCATGGGGAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATTAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCATTAGTCGATAATCTCGCCTTCGATATCGTCGCTCCGCTAATCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCACTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGTATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTACCGTTTAGCCCGGACTCTACCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATACGCGCCTACGACAGGTATCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGCCGACTCACGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTGCATGTAGAATTAGTAGACAGTGAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTCATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAACGGTTTGATTTTCAAACTATTCAACATGGGTGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTTAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCCAGTAGAAACAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTCTTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGTATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGTCAATCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACGCACATAGACACCCTTCAATCTCTACAATCCCGCTTTTGCAGGTTAGCCGTCGGAGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCTATACAGAAATACATGAAGTCAGCGTCGGAACGGTACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTAGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTCGCACTAGACGCCTTCAGCTCTAGGAGCAGGCTTAGGGACCTCGGGGGAGGGAGTTGGAAGAATGAAATGAAAAATGATATTGAGTGA

Protein

MDAVFAEFLRLRYPKLTSEFQAFKADHTASPLVDSTELAAPASPVPACKASASSTAASVVPAVPASPILASKTAASSAVVTVPAARSSAASVAPSKTPTRRSPAPASSSSDSDSEMEVDLAPASSTDGFTLVQKGKKRAAESRAPAAAKISKAANASRPRPQTPVAPPARATPSPRTVAQNKAQTPPPVILQEKAAWERVSLALKAKNINFTNARNLANGIQIKVRTSDDHRALSSYLRKERISFHTYTLQEERELRAVIRGIPKELDAELVKADLLEQGLPVNSVHRMHTGRGREPYNMVLVALQPTPEVQETLLKPARRDPKIANYNMVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDNLAFDIVAPLIPTHYPLNIAHRPDILDIALLKNVTLHLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVYWHTLGISLAESDPPSLPFSPDSTPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDRYPTAENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARRLTAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFSQSIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIQKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSRSRLRDLGGGSWKNEMKNDIE

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139W8G9   A0A139WA11   V5GNF3   X1WLB2   A0A2S2PPK8   A0A023EYS8   X1WNI2   A0A2S2QEE0   J9LC21   K7IN67   A0A023EZE6   X1WZH0   A0A224XB44   A0A224X6Q4   A0A2S2Q383   A0A2J7R7D0   A0A224X6S1   J9LFC9   A0A087UGF5   A0A2J7PDM0   A0A2J7QB68   A0A224X6T4   A0A2M4BD67   A0A2M4BDV6   A0A224XI99   A0A224X6U5   A0A069DZL8   A0A2H8TF37   A0A3N5Z7I3   A0A0A9YJ00   A0A2S2R9D4   A0A224XIB0   Q07995   Q9NBX4   A0A2S2NH02   Q95SX7   A0A224X746   A0A224XJI0   A0A2M4CV52   A0A069DX78   A0A023F069   A0A224X724   A0A2M4CV42   A0A2S2PJG2   A0A224X6R6   A0A2M4BD83   A0A1Y1KFR3   A0A023F0I3   A0A2S2NPG3   A0A2A4IUM2   A0A2H8TKI9   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A2S2NPJ7   Q8T9X4   Q8I7P8   A0A2S2PHL7   A0A142LX49  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    20075255    26334808    30086797    25401762    8387152    11405632    7753626    12537569    25527032   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    ABLF02042518    ABLF02057746    GGMR01018716    MBY31335.1    GBBI01004395    JAC14317.1    ABLF02008153    ABLF02008462    ABLF02008464    GGMS01006359    MBY75562.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GBBI01004571    JAC14141.1    ABLF02034467    GFTR01008262    JAW08164.1    GFTR01008279    JAW08147.1    GGMS01002992    MBY72195.1    NEVH01006736    PNF36716.1    GFTR01008271    JAW08155.1    ABLF02023911    KK119692    KFM76444.1    NEVH01026386    PNF14434.1    NEVH01016302    PNF25823.1    GFTR01008261    JAW08165.1    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    GFTR01008256    JAW08170.1    GFTR01008251    JAW08175.1    GBGD01000415    JAC88474.1    GFXV01000908    MBW12713.1    RPOV01000134    RPJ78669.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GGMS01017365    MBY86568.1    GFTR01008246    JAW08180.1    S59870    AAB26437.2    AF237761    AAF81411.1    GGMR01003864    MBY16483.1    AY060438    AAL25477.1    GFTR01008151    JAW08275.1    GFTR01008257    JAW08169.1    GGFL01004957    MBW69135.1    GBGD01000389    JAC88500.1    GBBI01003810    JAC14902.1    GFTR01008169    JAW08257.1    GGFL01005012    MBW69190.1    GGMR01016905    MBY29524.1    GFTR01008269    JAW08157.1    GGFJ01001822    MBW50963.1    GEZM01084969    JAV60363.1    GBBI01003747    JAC14965.1    GGMR01006408    MBY19027.1    NWSH01007753    PCG62823.1    GFXV01002840    MBW14645.1    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    GGMR01006491    MBY19110.1    AF456125    AAL57609.1    AY180919    AAN87272.1    GGMR01016296    MBY28915.1    KU543685    AMS38375.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000002358    UP000235965    UP000054359    + More
UP000218220   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q9NBX4    Q95SX7    Q8T9X4    + More
Q8I7P8   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139W8G9   A0A139WA11   V5GNF3   X1WLB2   A0A2S2PPK8   A0A023EYS8   X1WNI2   A0A2S2QEE0   J9LC21   K7IN67   A0A023EZE6   X1WZH0   A0A224XB44   A0A224X6Q4   A0A2S2Q383   A0A2J7R7D0   A0A224X6S1   J9LFC9   A0A087UGF5   A0A2J7PDM0   A0A2J7QB68   A0A224X6T4   A0A2M4BD67   A0A2M4BDV6   A0A224XI99   A0A224X6U5   A0A069DZL8   A0A2H8TF37   A0A3N5Z7I3   A0A0A9YJ00   A0A2S2R9D4   A0A224XIB0   Q07995   Q9NBX4   A0A2S2NH02   Q95SX7   A0A224X746   A0A224XJI0   A0A2M4CV52   A0A069DX78   A0A023F069   A0A224X724   A0A2M4CV42   A0A2S2PJG2   A0A224X6R6   A0A2M4BD83   A0A1Y1KFR3   A0A023F0I3   A0A2S2NPG3   A0A2A4IUM2   A0A2H8TKI9   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A2S2NPJ7   Q8T9X4   Q8I7P8   A0A2S2PHL7   A0A142LX49  

KEGG

105841788    no KO assigned | (RefSeq) predicted GPI-anchored protein 58

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1175

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.8968

Exp number, first 60 AAs:

0.00013

Total prob of N-in:

0.00011

outside

1  -  1175

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

18.831605

CSRT

0

Interpretation

Uncertain