Gene
KWMTBOMO06818
Pre Gene Modal
BGIBMGA012102
Annotation
PREDICTED:_mediator_of_RNA_polymerase_II_transcription_subunit_10_[Papilio_polytes]
Full name
Mediator of RNA polymerase II transcription subunit 10
Alternative Name
Mediator complex subunit 10
dMED10
dTRAP15
dMED10
dTRAP15
Location in the cell
Nuclear Reliability : 2.794
Sequence
CDS
ATGTCGTCTCCTTTAGAAAATCTTGAAACTCAACTTGAAATGTTCATTGAAAATGTGAGACAAATTCGTATAATCGTCAGTGATTTTCAACCTCAGGGGCAAAGTGTACTGAATCAAAAAATTCAGTCCTTAGTGACCGGATTGCAGGAAATTGACAAATTGAAGTCACAAGTTCATGATATCCACGTACCAACAGAAGTCTTTGATTACATTGATCAAGGCCGTAACCCACAGCTCTACACAAAGGACTGCATAGATAAAGCATTGGCTAAAAATGAAGAGGTGAAAGGAAAAATTGATTCATACAAGCGATTCAAAACTCATTTACTTTCTGAGCTATCGAAGACCTTCCCTAATGAGATTACAAAGTATAAGGCACTTAGGGGTGGAGAATAA
Protein
MSSPLENLETQLEMFIENVRQIRIIVSDFQPQGQSVLNQKIQSLVTGLQEIDKLKSQVHDIHVPTEVFDYIDQGRNPQLYTKDCIDKALAKNEEVKGKIDSYKRFKTHLLSELSKTFPNEITKYKALRGGE
Summary
Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for activated transcription of the MtnA, MtnB and MtnD genes.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for activated transcription of the MtnA, MtnB and MtnD genes.
Subunit
Component of the Mediator complex.
Component of the Mediator complex (By similarity). Interacts with MED4 and MED21.
Component of the Mediator complex (By similarity). Interacts with MED4 and MED21.
Similarity
Belongs to the Mediator complex subunit 10 family.
Keywords
Activator
Complete proteome
Nucleus
Reference proteome
Transcription
Transcription regulation
Feature
chain Mediator of RNA polymerase II transcription subunit 10
Uniprot
H9JRE2
A0A2A4J9P6
A0A194R904
A0A2H1VYD2
A0A194PGD8
A0A212EI35
+ More
A0A1E1WB81 A0A3S2M4C4 S4PTA0 A0A0L7KPN6 A0A1Q3FF46 A0A023EDP3 B0W9F2 E2BM56 K7J7Q2 A0A182PJW9 A0A182UNL4 A0A182KC77 A0A182TMN2 A0A084VDH2 A0A182LLH6 A0A182X8M3 A0A182II85 Q7Q5R5 Q16G71 A0A182QUI5 A0A182M1M7 A0A182RDF7 A0A182WCJ6 E0VFI5 A0A182NH26 A0A182YPX5 A0A2J7Q792 A0A182J5T7 A0A2M3Z8Z1 A0A2M4AIY8 A0A2M4C389 W5JS19 A0A182G094 E9JAB3 A0A195CUP8 E2AC59 A0A026VUE9 A0A0L7R0G6 A0A154PP43 A0A0N0U5K6 A0A2A3E7D5 A0A087ZVE0 F4WC77 A0A195BK70 A0A158N9Y9 A0A195FSJ2 N6UCP1 A0A1B0CDE0 A0A1B0CBB7 A0A195EKF2 A0A151WHA1 A0A0A9WC54 A0A1B0FCA9 A0A1A9X7N6 A0A1A9ULK1 A0A1B0AX34 A0A1A9Z4N6 A0A1A9W257 A0A1B6HMJ3 A0A0P4VVS9 R4FLE9 A0A1I8NNC9 T1P8U0 A0A1L8DFU4 A0A1L8EH41 A0A1Y1L774 A0A023FB69 A0A0L0C7L2 W8C874 A0A0K8W0J6 A0A034WWL6 D6WDP1 A0A1B6M3B9 U5EK63 A0A0C9RAU8 E9GEY5 B3M8Q4 A0A0K8TR03 A0A0P5QP78 A0A1W4UW46 B4HJ36 B3NI68 B4QM90 M9PFU7 B4ITT7 Q9GYU7 A0A0P5XHF2 A0A0P5AFA3 A0A0P5UDK5 A0A0P5DR14 A0A0P4Y2F2 A0A0P4Y296 A0A3B0KKG7 Q29EM4
A0A1E1WB81 A0A3S2M4C4 S4PTA0 A0A0L7KPN6 A0A1Q3FF46 A0A023EDP3 B0W9F2 E2BM56 K7J7Q2 A0A182PJW9 A0A182UNL4 A0A182KC77 A0A182TMN2 A0A084VDH2 A0A182LLH6 A0A182X8M3 A0A182II85 Q7Q5R5 Q16G71 A0A182QUI5 A0A182M1M7 A0A182RDF7 A0A182WCJ6 E0VFI5 A0A182NH26 A0A182YPX5 A0A2J7Q792 A0A182J5T7 A0A2M3Z8Z1 A0A2M4AIY8 A0A2M4C389 W5JS19 A0A182G094 E9JAB3 A0A195CUP8 E2AC59 A0A026VUE9 A0A0L7R0G6 A0A154PP43 A0A0N0U5K6 A0A2A3E7D5 A0A087ZVE0 F4WC77 A0A195BK70 A0A158N9Y9 A0A195FSJ2 N6UCP1 A0A1B0CDE0 A0A1B0CBB7 A0A195EKF2 A0A151WHA1 A0A0A9WC54 A0A1B0FCA9 A0A1A9X7N6 A0A1A9ULK1 A0A1B0AX34 A0A1A9Z4N6 A0A1A9W257 A0A1B6HMJ3 A0A0P4VVS9 R4FLE9 A0A1I8NNC9 T1P8U0 A0A1L8DFU4 A0A1L8EH41 A0A1Y1L774 A0A023FB69 A0A0L0C7L2 W8C874 A0A0K8W0J6 A0A034WWL6 D6WDP1 A0A1B6M3B9 U5EK63 A0A0C9RAU8 E9GEY5 B3M8Q4 A0A0K8TR03 A0A0P5QP78 A0A1W4UW46 B4HJ36 B3NI68 B4QM90 M9PFU7 B4ITT7 Q9GYU7 A0A0P5XHF2 A0A0P5AFA3 A0A0P5UDK5 A0A0P5DR14 A0A0P4Y2F2 A0A0P4Y296 A0A3B0KKG7 Q29EM4
Pubmed
19121390
26354079
22118469
23622113
26227816
24945155
+ More
26483478 20798317 20075255 24438588 20966253 12364791 17510324 20566863 25244985 20920257 23761445 21282665 24508170 30249741 21719571 21347285 23537049 25401762 26823975 27129103 25315136 28004739 25474469 26108605 24495485 25348373 18362917 19820115 21292972 17994087 26369729 22936249 10731132 12537568 12537572 12537573 12537574 16110336 17569856 17569867 26109357 26109356 17550304 12537569 15477388 16751183 15632085
26483478 20798317 20075255 24438588 20966253 12364791 17510324 20566863 25244985 20920257 23761445 21282665 24508170 30249741 21719571 21347285 23537049 25401762 26823975 27129103 25315136 28004739 25474469 26108605 24495485 25348373 18362917 19820115 21292972 17994087 26369729 22936249 10731132 12537568 12537572 12537573 12537574 16110336 17569856 17569867 26109357 26109356 17550304 12537569 15477388 16751183 15632085
EMBL
BABH01016272
NWSH01002489
PCG68180.1
KQ460779
KPJ12351.1
ODYU01005213
+ More
SOQ45850.1 KQ459606 KPI91769.1 AGBW02014707 OWR41152.1 GDQN01006867 GDQN01004668 JAT84187.1 JAT86386.1 RSAL01000045 RVE50615.1 GAIX01012403 JAA80157.1 JTDY01007674 KOB65031.1 GFDL01008880 JAV26165.1 JXUM01102812 GAPW01005946 GAPW01005945 KQ564754 JAC07653.1 KXJ71782.1 DS231864 EDS40177.1 GL449158 EFN83182.1 AAZX01010627 ATLV01011337 KE524664 KFB36016.1 APCN01000030 AAAB01008960 CH478321 AXCN02000346 AXCM01003359 AAZO01001843 DS235113 EEB12141.1 NEVH01017447 PNF24451.1 GGFM01004243 MBW24994.1 GGFK01007438 MBW40759.1 GGFJ01010645 MBW59786.1 ADMH02000262 ETN67202.1 GL770128 EFZ10240.1 KQ977276 KYN04408.1 GL438422 EFN68975.1 KK107871 QOIP01000007 EZA47377.1 RLU20193.1 KQ414670 KOC64316.1 KQ435007 KZC13639.1 KQ435783 KOX74632.1 KZ288345 PBC27618.1 GL888070 EGI68057.1 KQ976455 KYM85048.1 ADTU01009911 KQ981305 KYN42869.1 APGK01034679 KB740914 KB632352 ENN78401.1 ERL93280.1 AJWK01007724 AJWK01004997 KQ978739 KYN28745.1 KQ983135 KYQ47188.1 GBHO01038633 GBHO01029164 GBRD01007797 GBRD01007796 GDHC01020110 GDHC01017248 GDHC01005814 JAG04971.1 JAG14440.1 JAG58024.1 JAP98518.1 JAQ01381.1 JAQ12815.1 CCAG010001627 JXJN01004989 GECU01031901 JAS75805.1 GDKW01001797 JAI54798.1 ACPB03013537 ACPB03013538 GAHY01001433 JAA76077.1 KA645104 AFP59733.1 GFDF01008854 JAV05230.1 GFDG01000772 JAV18027.1 GEZM01064749 JAV68651.1 GBBI01000544 GEMB01002104 JAC18168.1 JAS01075.1 JRES01000902 KNC27399.1 GAMC01000097 JAC06459.1 GDHF01007631 JAI44683.1 GAKP01000337 JAC58615.1 KQ971322 EFA00809.1 GEBQ01032170 GEBQ01009528 JAT07807.1 JAT30449.1 GANO01001930 JAB57941.1 GBYB01010217 JAG79984.1 GL732541 EFX81997.1 CH902618 EDV40028.1 GDAI01000809 JAI16794.1 GDIQ01111498 JAL40228.1 CH480815 EDW41692.1 CH954178 EDV52224.2 CM000363 CM002912 EDX10659.1 KMY99971.1 AE014296 KX531601 AGB94624.1 ANY27411.1 CM000159 CH891731 EDW95466.2 EDW99800.2 AY005465 AY118450 GDIP01072212 JAM31503.1 GDIP01201295 GDIP01199998 JAJ23404.1 GDIP01116112 JAL87602.1 GDIP01158757 JAJ64645.1 GDIP01235703 JAI87698.1 GDIP01239904 GDIP01237352 JAI86049.1 OUUW01000012 SPP87019.1 CH379070 EAL30036.2
SOQ45850.1 KQ459606 KPI91769.1 AGBW02014707 OWR41152.1 GDQN01006867 GDQN01004668 JAT84187.1 JAT86386.1 RSAL01000045 RVE50615.1 GAIX01012403 JAA80157.1 JTDY01007674 KOB65031.1 GFDL01008880 JAV26165.1 JXUM01102812 GAPW01005946 GAPW01005945 KQ564754 JAC07653.1 KXJ71782.1 DS231864 EDS40177.1 GL449158 EFN83182.1 AAZX01010627 ATLV01011337 KE524664 KFB36016.1 APCN01000030 AAAB01008960 CH478321 AXCN02000346 AXCM01003359 AAZO01001843 DS235113 EEB12141.1 NEVH01017447 PNF24451.1 GGFM01004243 MBW24994.1 GGFK01007438 MBW40759.1 GGFJ01010645 MBW59786.1 ADMH02000262 ETN67202.1 GL770128 EFZ10240.1 KQ977276 KYN04408.1 GL438422 EFN68975.1 KK107871 QOIP01000007 EZA47377.1 RLU20193.1 KQ414670 KOC64316.1 KQ435007 KZC13639.1 KQ435783 KOX74632.1 KZ288345 PBC27618.1 GL888070 EGI68057.1 KQ976455 KYM85048.1 ADTU01009911 KQ981305 KYN42869.1 APGK01034679 KB740914 KB632352 ENN78401.1 ERL93280.1 AJWK01007724 AJWK01004997 KQ978739 KYN28745.1 KQ983135 KYQ47188.1 GBHO01038633 GBHO01029164 GBRD01007797 GBRD01007796 GDHC01020110 GDHC01017248 GDHC01005814 JAG04971.1 JAG14440.1 JAG58024.1 JAP98518.1 JAQ01381.1 JAQ12815.1 CCAG010001627 JXJN01004989 GECU01031901 JAS75805.1 GDKW01001797 JAI54798.1 ACPB03013537 ACPB03013538 GAHY01001433 JAA76077.1 KA645104 AFP59733.1 GFDF01008854 JAV05230.1 GFDG01000772 JAV18027.1 GEZM01064749 JAV68651.1 GBBI01000544 GEMB01002104 JAC18168.1 JAS01075.1 JRES01000902 KNC27399.1 GAMC01000097 JAC06459.1 GDHF01007631 JAI44683.1 GAKP01000337 JAC58615.1 KQ971322 EFA00809.1 GEBQ01032170 GEBQ01009528 JAT07807.1 JAT30449.1 GANO01001930 JAB57941.1 GBYB01010217 JAG79984.1 GL732541 EFX81997.1 CH902618 EDV40028.1 GDAI01000809 JAI16794.1 GDIQ01111498 JAL40228.1 CH480815 EDW41692.1 CH954178 EDV52224.2 CM000363 CM002912 EDX10659.1 KMY99971.1 AE014296 KX531601 AGB94624.1 ANY27411.1 CM000159 CH891731 EDW95466.2 EDW99800.2 AY005465 AY118450 GDIP01072212 JAM31503.1 GDIP01201295 GDIP01199998 JAJ23404.1 GDIP01116112 JAL87602.1 GDIP01158757 JAJ64645.1 GDIP01235703 JAI87698.1 GDIP01239904 GDIP01237352 JAI86049.1 OUUW01000012 SPP87019.1 CH379070 EAL30036.2
Proteomes
UP000005204
UP000218220
UP000053240
UP000053268
UP000007151
UP000283053
+ More
UP000037510 UP000069940 UP000249989 UP000002320 UP000008237 UP000002358 UP000075885 UP000075903 UP000075881 UP000075902 UP000030765 UP000075882 UP000076407 UP000075840 UP000007062 UP000008820 UP000075886 UP000075883 UP000075900 UP000075920 UP000009046 UP000075884 UP000076408 UP000235965 UP000075880 UP000000673 UP000069272 UP000078542 UP000000311 UP000053097 UP000279307 UP000053825 UP000076502 UP000053105 UP000242457 UP000005203 UP000007755 UP000078540 UP000005205 UP000078541 UP000019118 UP000030742 UP000092461 UP000078492 UP000075809 UP000092444 UP000092443 UP000078200 UP000092460 UP000092445 UP000091820 UP000015103 UP000095300 UP000095301 UP000037069 UP000007266 UP000000305 UP000007801 UP000192221 UP000001292 UP000008711 UP000000304 UP000000803 UP000002282 UP000268350 UP000001819
UP000037510 UP000069940 UP000249989 UP000002320 UP000008237 UP000002358 UP000075885 UP000075903 UP000075881 UP000075902 UP000030765 UP000075882 UP000076407 UP000075840 UP000007062 UP000008820 UP000075886 UP000075883 UP000075900 UP000075920 UP000009046 UP000075884 UP000076408 UP000235965 UP000075880 UP000000673 UP000069272 UP000078542 UP000000311 UP000053097 UP000279307 UP000053825 UP000076502 UP000053105 UP000242457 UP000005203 UP000007755 UP000078540 UP000005205 UP000078541 UP000019118 UP000030742 UP000092461 UP000078492 UP000075809 UP000092444 UP000092443 UP000078200 UP000092460 UP000092445 UP000091820 UP000015103 UP000095300 UP000095301 UP000037069 UP000007266 UP000000305 UP000007801 UP000192221 UP000001292 UP000008711 UP000000304 UP000000803 UP000002282 UP000268350 UP000001819
Pfam
PF09748 Med10
Interpro
IPR019145
Mediator_Med10
ProteinModelPortal
H9JRE2
A0A2A4J9P6
A0A194R904
A0A2H1VYD2
A0A194PGD8
A0A212EI35
+ More
A0A1E1WB81 A0A3S2M4C4 S4PTA0 A0A0L7KPN6 A0A1Q3FF46 A0A023EDP3 B0W9F2 E2BM56 K7J7Q2 A0A182PJW9 A0A182UNL4 A0A182KC77 A0A182TMN2 A0A084VDH2 A0A182LLH6 A0A182X8M3 A0A182II85 Q7Q5R5 Q16G71 A0A182QUI5 A0A182M1M7 A0A182RDF7 A0A182WCJ6 E0VFI5 A0A182NH26 A0A182YPX5 A0A2J7Q792 A0A182J5T7 A0A2M3Z8Z1 A0A2M4AIY8 A0A2M4C389 W5JS19 A0A182G094 E9JAB3 A0A195CUP8 E2AC59 A0A026VUE9 A0A0L7R0G6 A0A154PP43 A0A0N0U5K6 A0A2A3E7D5 A0A087ZVE0 F4WC77 A0A195BK70 A0A158N9Y9 A0A195FSJ2 N6UCP1 A0A1B0CDE0 A0A1B0CBB7 A0A195EKF2 A0A151WHA1 A0A0A9WC54 A0A1B0FCA9 A0A1A9X7N6 A0A1A9ULK1 A0A1B0AX34 A0A1A9Z4N6 A0A1A9W257 A0A1B6HMJ3 A0A0P4VVS9 R4FLE9 A0A1I8NNC9 T1P8U0 A0A1L8DFU4 A0A1L8EH41 A0A1Y1L774 A0A023FB69 A0A0L0C7L2 W8C874 A0A0K8W0J6 A0A034WWL6 D6WDP1 A0A1B6M3B9 U5EK63 A0A0C9RAU8 E9GEY5 B3M8Q4 A0A0K8TR03 A0A0P5QP78 A0A1W4UW46 B4HJ36 B3NI68 B4QM90 M9PFU7 B4ITT7 Q9GYU7 A0A0P5XHF2 A0A0P5AFA3 A0A0P5UDK5 A0A0P5DR14 A0A0P4Y2F2 A0A0P4Y296 A0A3B0KKG7 Q29EM4
A0A1E1WB81 A0A3S2M4C4 S4PTA0 A0A0L7KPN6 A0A1Q3FF46 A0A023EDP3 B0W9F2 E2BM56 K7J7Q2 A0A182PJW9 A0A182UNL4 A0A182KC77 A0A182TMN2 A0A084VDH2 A0A182LLH6 A0A182X8M3 A0A182II85 Q7Q5R5 Q16G71 A0A182QUI5 A0A182M1M7 A0A182RDF7 A0A182WCJ6 E0VFI5 A0A182NH26 A0A182YPX5 A0A2J7Q792 A0A182J5T7 A0A2M3Z8Z1 A0A2M4AIY8 A0A2M4C389 W5JS19 A0A182G094 E9JAB3 A0A195CUP8 E2AC59 A0A026VUE9 A0A0L7R0G6 A0A154PP43 A0A0N0U5K6 A0A2A3E7D5 A0A087ZVE0 F4WC77 A0A195BK70 A0A158N9Y9 A0A195FSJ2 N6UCP1 A0A1B0CDE0 A0A1B0CBB7 A0A195EKF2 A0A151WHA1 A0A0A9WC54 A0A1B0FCA9 A0A1A9X7N6 A0A1A9ULK1 A0A1B0AX34 A0A1A9Z4N6 A0A1A9W257 A0A1B6HMJ3 A0A0P4VVS9 R4FLE9 A0A1I8NNC9 T1P8U0 A0A1L8DFU4 A0A1L8EH41 A0A1Y1L774 A0A023FB69 A0A0L0C7L2 W8C874 A0A0K8W0J6 A0A034WWL6 D6WDP1 A0A1B6M3B9 U5EK63 A0A0C9RAU8 E9GEY5 B3M8Q4 A0A0K8TR03 A0A0P5QP78 A0A1W4UW46 B4HJ36 B3NI68 B4QM90 M9PFU7 B4ITT7 Q9GYU7 A0A0P5XHF2 A0A0P5AFA3 A0A0P5UDK5 A0A0P5DR14 A0A0P4Y2F2 A0A0P4Y296 A0A3B0KKG7 Q29EM4
PDB
5N9J
E-value=9.75654e-06,
Score=110
Ontologies
GO
Topology
Subcellular location
Nucleus
Length:
131
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0
Exp number, first 60 AAs:
0
Total prob of N-in:
0.05535
outside
1 - 131
Population Genetic Test Statistics
Pi
15.741924
Theta
17.181201
Tajima's D
-0.347009
CLR
0.639774
CSRT
0.277986100694965
Interpretation
Uncertain
