Gene

KWMTBOMO06787  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012116

Annotation

PREDICTED:_SUMO-activating_enzyme_subunit_2_[Amyelois_transitella]

Location

Bomo_Chr11(-):14880135-14885951      View in EpiBrowser

Full name

SUMO-activating enzyme subunit      

Location in the cell

Cytoplasmic   Reliability : 2.149 Nuclear   Reliability : 1.709

CDS

ATGGTCGCGAGGGTCGCTGGCGTTTTCGATGAGAAATTGACAGAAGCTATTGCAAATTCTAAATTGCTGGTAGTGGGCGCCGGCGGCATTGGTTGTGAGATCCTTAAAAATCTCGTGCTAACCGGCTTCCCATATATTGAAATTATCGACCTTGATACTATCGACGTAAGCAACTTGAATCGTCAGTTTCTTTTTCACAAAGAGCATGTTGGGAAATCAAAGGCTCAAGTTGCAAAGGATAGCGCCCTTAGTTTCAACCCTAACGTAACAATCGTAGCTCACCATGACAGTGTAATCAGCAATGACTATGGTGTAAAATACTTCAAACAGTTCAACATTGTGATGAATGCACTGGACAATCGTGTTGCCCGTAACCATGTTAATAGATTGTGTCTTGCTGCTGATGTACCTCTTATAGAGACAGGTACAGCAGGATATGCTGGTCAGGTGGAGCTCATCAAGAAAGGTCTGACTCAATGTTATGAATGCCAGCCTAAAGCACCACAGAAATCATTCCCAGGTTGCACAATTCGTAATACACCTTCAGAACCTATTCACTGCATTGTATGGGCAAAACACCTCTTCAACCAATTGTTTGGAGAAGAAGACCCTGATCAAGATGTGAGTCCTGATACAGCTGACCCTGAGGCTGCAGGTGATGCTGGACAATCAGCGTTGTCTAATGAAAGTACTACTGCCGGTAATGTTGAAAGAAAAAGTACCAGAGCCTGGGCAGCAGAAACTAATTATGAACCAGAAAAGTTATTCACAAAATTATTTGGTGATGATATCCGTTACTTACTATCTATGGAGAATTTGTGGAAGAAACGTCGGCCTCCCACTCCACTGTCATGGGAAAATCTACCTGGAAAAGATGCTCCAAAAATTCAACATTCAGGGTTGCCAGACCAAAGAGTTTGGACAGTATATGAATGTGCACAAGTATTTGCAGCAAGCTGCAAGGCTCTACAGACAGATTTGAAATCGCGTCCGGGTGACGACCATCTTGTATGGGACAAAGATGAAAAAAGTGCCATGGATTTTGTAACTGCCTGTGCTAACATACGCGCACATATCTTTAATATACCACTAAAATCACGATTCGAAATCAAATCAATGGCAGGTAACATCATTCCGGCAATCGCAACGGCCAATGCAATAGTGGCTGGTCTGGCTGTGTTACGTGCACAGTCCATACTGAAAGGAGAAATAGAAAGCTGCACTAGTGTGTACTTGAGACCTAAAGTAAACCACAGGGGACAGCTTTTTGTTCCTGAAAAAACATTAACTCCACCTAATCCTAAGTGCTATGTCTGTCCCCCAAAGCCAGAAGTGGCTCTAGCATGCAACTTGAAAAAACTCACATTGAAAGACCTAGATACGGCTTTCAAAGAGGGCTTAAACATGCAAGCCCCAGACGCCAGTGTAGAAGGCAAAGGTCTTGTTATTTTATCTTCCGAACCAGGAGAAACTGAACACAACAATGACAAAACTCTGGAACAAATCGGCTTGAATGACGGCTGTGCATTACTTGTGGATGATTTCTTACAAAACTATGAAGTCAGGGTCAGACTGCAGCAGGAAGATGAAGAAAATTCTTGGCGGCTGGTAACAGATACCGATGAACCGATGCCGGCGCCTAAAGCAGCAGAAAATTCCGCTAACGGCTCCAATGGCGCTAAGGATCCTGCACCAGGACCTTCCAGATCTCGCCAGGACAGCGACAGTGATATGGAGATAATCGAGGAAGATGACGACGAACCCACAATGAAACCACCTAAGCGCAGGCGTGTCGAAATGTCAGATGAAGTTGTCGAAATATGTTAA

Protein

MVARVAGVFDEKLTEAIANSKLLVVGAGGIGCEILKNLVLTGFPYIEIIDLDTIDVSNLNRQFLFHKEHVGKSKAQVAKDSALSFNPNVTIVAHHDSVISNDYGVKYFKQFNIVMNALDNRVARNHVNRLCLAADVPLIETGTAGYAGQVELIKKGLTQCYECQPKAPQKSFPGCTIRNTPSEPIHCIVWAKHLFNQLFGEEDPDQDVSPDTADPEAAGDAGQSALSNESTTAGNVERKSTRAWAAETNYEPEKLFTKLFGDDIRYLLSMENLWKKRRPPTPLSWENLPGKDAPKIQHSGLPDQRVWTVYECAQVFAASCKALQTDLKSRPGDDHLVWDKDEKSAMDFVTACANIRAHIFNIPLKSRFEIKSMAGNIIPAIATANAIVAGLAVLRAQSILKGEIESCTSVYLRPKVNHRGQLFVPEKTLTPPNPKCYVCPPKPEVALACNLKKLTLKDLDTAFKEGLNMQAPDASVEGKGLVILSSEPGETEHNNDKTLEQIGLNDGCALLVDDFLQNYEVRVRLQQEDEENSWRLVTDTDEPMPAPKAAENSANGSNGAKDPAPGPSRSRQDSDSDMEIIEEDDDEPTMKPPKRRRVEMSDEVVEIC

Subunit

Heterodimer.

Similarity

Belongs to the ubiquitin-activating E1 family.

Uniprot

H9JRF6   A0A2H1V9X0   A0A194Q9D4   A0A212EK97   A0A3S2LYU5   S4P6Q4   + More
A0A2A4J3G1   A0A2J7QGR2   A0A067R5B3   A0A088ARE4   A0A2A3EE79   A0A232EM52   A0A0M9A6E1   K7IM19   A0A0L7RIJ3   A0A1B6J1A6   Q16SB9   A0A023EVG3   E9J4H9   A0A182GE15   A0A158NM78   A0A151JWD3   B0WLL0   F4WK04   A0A1Q3F0M9   E0VL42   E2A8Z0   A0A026WHT9   A0A151IRI2   A0A151X2E0   A0A151IE81   A0A0J7L327   A0A195BYV4   A0A182RK53   E2B7T3   A0A0C9QK38   U5EXW5   A0A336K919   A0A182LUB3   A0A182WFG0   A0A1B6F7D1   A0A182YSB3   A0A182JX61   A0A182X5W3   W5JJ08   A0A182SCW5   A0A182VC82   A0A182KN71   A0A182IBJ6   A0A2M4BGD2   A0A2M4BG96   A0A2M4BGA4   A0A182TP29   Q7Q8G9   A0A182P488   A0A2M4AIY1   A0A182ISB0   A0A2M4AJ56   A0A210PH49   A0A182NGP2   A0A3Q0J3U9   A0A084W7N9   A0A182Q1M4   A0A2C9K596   A0A1S3J3I5   A0A2R2MPD2   A0A1S3J4Q2   A0A0B7BGF8   A0A1J1HST2   A0A1B0CYM6   K1Q5G9   A0A0L0C1Y7   A0A1B6DVJ7   V4ATI1   A0A1L8DST4   A0A0T6B393   A0A2T7NHS4   A0A1A9ZX08   A0A2B4RUV6   A0A1W4WFV1   A0A1Y1KF70   A0A1B0G3Y6   A0A1A9XIL0   A0A1B0BCP7   A0A3M6U7E3   A0A0N8DRQ8   A0A1I8PHE9   A0A0P5E456   A0A0P4XPT0   A0A0N8CL88   A0A0P5ZWY1   A0A0P4YU31   A0A0P6E5M0   A0A165A5B7   A0A1I8MXD0   A0A0P5XLD6   A0A1A9XPX7   A0A1A9VN27   A0A1B0G2L0  

Pubmed

19121390    26354079    22118469    23622113    24845553    28648823    + More
20075255    17510324    24945155    21282665    26483478    21347285    21719571    20566863    20798317    24508170    30249741    25244985    20920257    23761445    20966253    12364791    14747013    17210077    28812685    24438588    15562597    22992520    26108605    23254933    28004739    30382153    25315136   

EMBL

BABH01016361    ODYU01001443    SOQ37643.1    KQ459252    KPJ02113.1    AGBW02014303    + More
OWR41906.1    RSAL01000107    RVE47291.1    GAIX01004929    JAA87631.1    NWSH01003386    PCG66409.1    NEVH01014359    PNF27775.1    KK852879    KDR14472.1    KZ288282    PBC29592.1    NNAY01003438    OXU19417.1    KQ435726    KOX78175.1    KQ414584    KOC70649.1    GECU01014816    JAS92890.1    CH477677    EAT37350.1    GAPW01000470    JAC13128.1    GL768105    EFZ12246.1    JXUM01056951    KQ561933    KXJ77119.1    ADTU01020341    KQ981652    KYN38631.1    DS231987    EDS30540.1    GL888190    EGI65454.1    GFDL01013939    JAV21106.1    DS235269    EEB14098.1    GL437703    EFN70089.1    KK107238    QOIP01000007    EZA54639.1    RLU20620.1    KQ981126    KYN09312.1    KQ982584    KYQ54419.1    KQ977890    KYM98974.1    LBMM01001137    KMQ96839.1    KQ976395    KYM93103.1    GL446209    EFN88226.1    GBYB01015168    JAG84935.1    GANO01000712    JAB59159.1    UFQS01000126    UFQT01000126    SSX00138.1    SSX20518.1    AXCM01002194    GECZ01027853    GECZ01023694    JAS41916.1    JAS46075.1    ADMH02001096    ETN64121.1    APCN01000707    GGFJ01002936    MBW52077.1    GGFJ01002934    MBW52075.1    GGFJ01002933    MBW52074.1    AAAB01008944    EAA10202.3    GGFK01007410    MBW40731.1    GGFK01007451    MBW40772.1    NEDP02076706    OWF35811.1    ATLV01021268    KE525315    KFB46233.1    AXCN02002080    HACG01044536    CEK91401.1    CVRI01000020    CRK91061.1    AJVK01009248    JH816675    EKC24155.1    JRES01000997    KNC26267.1    GEDC01007604    JAS29694.1    KB201262    ESO98215.1    GFDF01004660    JAV09424.1    LJIG01016014    KRT81872.1    PZQS01000012    PVD20729.1    LSMT01000246    PFX22234.1    GEZM01085156    JAV60173.1    CCAG010017310    JXJN01012081    RCHS01002146    RMX49378.1    GDIP01007383    JAM96332.1    GDIP01146787    JAJ76615.1    GDIP01239485    GDIP01230635    GDIP01071953    JAI83916.1    GDIP01120743    GDIP01082681    JAL82971.1    GDIP01124894    GDIP01038205    JAM65510.1    GDIP01222325    JAJ01077.1    GDIQ01068658    JAN26079.1    LRGB01000642    KZS17193.1    GDIP01071952    JAM31763.1    CCAG010007952   

Proteomes

UP000005204    UP000053268    UP000007151    UP000283053    UP000218220    UP000235965    + More
UP000027135    UP000005203    UP000242457    UP000215335    UP000053105    UP000002358    UP000053825    UP000008820    UP000069940    UP000249989    UP000005205    UP000078541    UP000002320    UP000007755    UP000009046    UP000000311    UP000053097    UP000279307    UP000078492    UP000075809    UP000078542    UP000036403    UP000078540    UP000075900    UP000008237    UP000075883    UP000075920    UP000076408    UP000075881    UP000076407    UP000000673    UP000075901    UP000075903    UP000075882    UP000075840    UP000075902    UP000007062    UP000075885    UP000075880    UP000242188    UP000075884    UP000079169    UP000030765    UP000075886    UP000076420    UP000085678    UP000183832    UP000092462    UP000005408    UP000037069    UP000030746    UP000245119    UP000092445    UP000225706    UP000192223    UP000092444    UP000092443    UP000092460    UP000275408    UP000095300    UP000076858    UP000095301    UP000078200   

PRIDE

H9JRF6   

Pfam

PF14732   UAE_UbL        + More
PF10585   UBA_e1_thiolCys
PF00899   ThiF
PF12796   Ank_2
PF16195   UBA2_C
PF07707   BACK
PF00651   BTB

Interpro

IPR023318   Ub_act_enz_dom_a_sf        + More
IPR000011   UBQ/SUMO-activ_enz_E1-like       
IPR028077   UAE_UbL_dom       
IPR019572   UBA_E1_Cys       
IPR035985   Ubiquitin-activating_enz       
IPR000594   ThiF_NAD_FAD-bd       
IPR033127   UBQ-activ_enz_E1_Cys_AS       
IPR030661   Uba2       
IPR036770   Ankyrin_rpt-contain_sf       
IPR020683   Ankyrin_rpt-contain_dom       
IPR002110   Ankyrin_rpt       
IPR032426   UBA2_C       
IPR011705   BACK       
IPR011333   SKP1/BTB/POZ_sf       
IPR000210   BTB/POZ_dom       

SUPFAM

SSF69572   SSF69572        + More
SSF48403   SSF48403       
SSF54695   SSF54695       

Gene 3D

1.10.10.520     1.25.40.20    

CDD

cd00204  ANK

ProteinModelPortal

H9JRF6   A0A2H1V9X0   A0A194Q9D4   A0A212EK97   A0A3S2LYU5   S4P6Q4   + More
A0A2A4J3G1   A0A2J7QGR2   A0A067R5B3   A0A088ARE4   A0A2A3EE79   A0A232EM52   A0A0M9A6E1   K7IM19   A0A0L7RIJ3   A0A1B6J1A6   Q16SB9   A0A023EVG3   E9J4H9   A0A182GE15   A0A158NM78   A0A151JWD3   B0WLL0   F4WK04   A0A1Q3F0M9   E0VL42   E2A8Z0   A0A026WHT9   A0A151IRI2   A0A151X2E0   A0A151IE81   A0A0J7L327   A0A195BYV4   A0A182RK53   E2B7T3   A0A0C9QK38   U5EXW5   A0A336K919   A0A182LUB3   A0A182WFG0   A0A1B6F7D1   A0A182YSB3   A0A182JX61   A0A182X5W3   W5JJ08   A0A182SCW5   A0A182VC82   A0A182KN71   A0A182IBJ6   A0A2M4BGD2   A0A2M4BG96   A0A2M4BGA4   A0A182TP29   Q7Q8G9   A0A182P488   A0A2M4AIY1   A0A182ISB0   A0A2M4AJ56   A0A210PH49   A0A182NGP2   A0A3Q0J3U9   A0A084W7N9   A0A182Q1M4   A0A2C9K596   A0A1S3J3I5   A0A2R2MPD2   A0A1S3J4Q2   A0A0B7BGF8   A0A1J1HST2   A0A1B0CYM6   K1Q5G9   A0A0L0C1Y7   A0A1B6DVJ7   V4ATI1   A0A1L8DST4   A0A0T6B393   A0A2T7NHS4   A0A1A9ZX08   A0A2B4RUV6   A0A1W4WFV1   A0A1Y1KF70   A0A1B0G3Y6   A0A1A9XIL0   A0A1B0BCP7   A0A3M6U7E3   A0A0N8DRQ8   A0A1I8PHE9   A0A0P5E456   A0A0P4XPT0   A0A0N8CL88   A0A0P5ZWY1   A0A0P4YU31   A0A0P6E5M0   A0A165A5B7   A0A1I8MXD0   A0A0P5XLD6   A0A1A9XPX7   A0A1A9VN27   A0A1B0G2L0  

PDB

3KYD     E-value=2.91026e-163,     Score=1478

KEGG

101743805    K10685 ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45] | (RefSeq) SUMO-activating enzyme subun

PATHWAY

04120    Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)

GO

GO:0046872   GO:0005524   GO:0016925   GO:0019948   GO:0031510   GO:0032446   GO:0005737   GO:0016021   GO:0008641   GO:0006464   GO:0006355   GO:0043565   GO:0016567   GO:0016020   GO:0005634   GO:0006260  

PANTHER

PTHR10953:SF5  

Length:

608

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.71592

Exp number, first 60 AAs:

0.70552

Total prob of N-in:

0.05175

outside

1  -  608

 

 

Pi

5.226232

Theta

14.376044

Tajima's D

-1.618822

CLR

1.291564

CSRT

0.0439978001099945

Interpretation

Uncertain