Gene

KWMTBOMO06782

Pre Gene Modal

BGIBMGA012036

Annotation

PREDICTED:_uncharacterized_protein_LOC100286771_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr11(+):14840182-14846233      View in EpiBrowser

Full name

Mini-chromosome maintenance complex-binding protein      

Location in the cell

Nuclear   Reliability : 3.222

CDS

ATGCATGAAAATATCATGAGCGATATCGAAACAACGACGCCGGATCGATGGATTGAGAATGAAAAAATAATGAAGAGCAAGTTGATGAAATTACCAAATTGGTACCAGATCCCACTAATTAATTCAAATGCTTCACATAATTTAACAGACGGAAACTTAGTGCGGTTCAGAGGCATGATCCAAGACATGCACAACCCTGAATTTTACTTTGAGAAATTTGAAGTATTTAACACAACAACAAATGAAGTAAAGGTTAAAAGTGGAAAATACAGAGATACTGCACATGTTTTGGAAAATGAGAAAATTAACTATTCTGAGAACCTAATCAGTGGTCAGCGACAGACTTTAGTTGTTGTGTCTATACCTGGGTTAAATGACTGGGTCCAACAACTAGAAGATAAACAAAACTATTTGAAACATTTAGAAGAACCACCAAATACTTCCAAAAGGCTTCACCCAAGTACAAAGTTAAAAAGAAGCTACGATGATACAGAAGATAATTTGGATGAAATGGAAGTTGATAATGAAGCTGTGAATAAGGAAATGAAGATTTTAGATCACAAAGATAATACACCTGATGTGGTTTCAAGAGAACATTTGTTAAATTATCCTCTACCTGATGTACCTAGCAAATCTTGCATTGTTAAGATTTACAGTGACAATGAAAATCTCAAGCTCAATGACATGATAGAAGTCATTGGATTTCTTTCTGTAGATCCATCCCTATCAGGCGAATTCAAGGAAGATAAGGATTCTATGATAGAGCTCCAGATTGAGAGTAGTGTCGAAATTATAACTCATAATCCTCCACCAAGCTTAGTACCACGATTGCATGCTGTTCATGTACAAAAATTGGAACATTGCAATCCATTACTTTCAAATAGTGTTGATCAAGGTGTGATTTTAAGTGAGGCAAACGCAGCAAGGGAGCATTTATTGAAAGCCTTGACGGAACTCTTACTGGGAGATCAATTAGCTGCTGAATATTTGATATGTCATCTTATTGCTTGTGTCTATCTTCGTCAAGATACTATGAACTTGGGACAGTTCTGTTTGAACCTATCAAATTTGCCAACACAGAAATATCCAAATTATGCACAACAGCTATATGATATTATCAAGCAATTTGTCACCAAAAGCTACTATTTACCACTTACCATTGAAAATATGAATACATTGACATTATTGCCTAAGAAAGACTATGAATGTAATCGTCTAGCTAGTGGAGTACTACAGCTCAGTAAAGATACGCATCTAATTTTGGATGAAACCAAGATGGAACAAGGTCGGCTCGATGCGACCGGCGTCAACAATATAGCTGCTCTCGGTAAAATGATTATGACACAGAAAGTTGAATATGATTTCAAATATTATAAAATGGAATTTGATTCAGATATCTCTGTGCTGGTATTGTCTGAAGGAAAGTCATTGTTGCCAAGTGATTACCATGTTCCATTGAAACCAGAAGAATCTTCACTAGAAATATTTGATGCCATAGTTGAAGCAGCCACATACTACTTAACGGAGGACTTGATGAATATGATCAGGGCGTATCTAACCAACCTGAAACTTGTGAAATATTCTATAACTGAAGACTTGCAGTTTGTAGAAAATGATTTCATAGATATGAGAAGTAAATCAAGCAGTGATAATCCCGTAACGGCAGACGATTTACATAGATTACTGGTGTTGGCGCGCCTGGTCAGTTTATCGCGCGGCCACGATACTCTAAGTAAAGAATGCTGGGACATCACAAAGGCAATGGAAACTGAAAGATTACATCGAGTGAAGAATAGAGTTGCCTCTACTGTATAA

Protein

MHENIMSDIETTTPDRWIENEKIMKSKLMKLPNWYQIPLINSNASHNLTDGNLVRFRGMIQDMHNPEFYFEKFEVFNTTTNEVKVKSGKYRDTAHVLENEKINYSENLISGQRQTLVVVSIPGLNDWVQQLEDKQNYLKHLEEPPNTSKRLHPSTKLKRSYDDTEDNLDEMEVDNEAVNKEMKILDHKDNTPDVVSREHLLNYPLPDVPSKSCIVKIYSDNENLKLNDMIEVIGFLSVDPSLSGEFKEDKDSMIELQIESSVEIITHNPPPSLVPRLHAVHVQKLEHCNPLLSNSVDQGVILSEANAAREHLLKALTELLLGDQLAAEYLICHLIACVYLRQDTMNLGQFCLNLSNLPTQKYPNYAQQLYDIIKQFVTKSYYLPLTIENMNTLTLLPKKDYECNRLASGVLQLSKDTHLILDETKMEQGRLDATGVNNIAALGKMIMTQKVEYDFKYYKMEFDSDISVLVLSEGKSLLPSDYHVPLKPEESSLEIFDAIVEAATYYLTEDLMNMIRAYLTNLKLVKYSITEDLQFVENDFIDMRSKSSSDNPVTADDLHRLLVLARLVSLSRGHDTLSKECWDITKAMETERLHRVKNRVASTV

Description

Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and may act by promoting the disassembly of the MCM complex from chromatin (By similarity).
Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the mcm complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. May also be required for sister chromatid cohesion.

Subunit

Interacts with the MCM complex.
Interacts with the mcm complex: associates with the mcm3-7 complex which lacks mcm2, while it does not interact with the mcm complex when mcm2 is present (mcm2-7 complex). Interacts with mcm7.

Similarity

Belongs to the MCMBP family.

Keywords

Cell cycle   Cell division   Complete proteome   DNA replication   Mitosis   Nucleus   Phosphoprotein   Reference proteome  

Feature

chain  Mini-chromosome maintenance complex-binding protein

Uniprot

H9JR76   A0A2H1V9Y4   A0A2A4J3Z2   A0A1E1WQ04   A0A194Q9P4   A0A194QPQ7   + More
A0A212F7Z6   S4PCJ5   D6WEZ4   A0A2J7PVP2   A0A1W4XKV9   A0A0T6B6P9   Q0IG57   A0A1S4F502   U4UHS8   W5JVF0   B4KJV3   N6TYT0   A0A182IP45   A0A182GT23   A0A067R5U4   A0A1I8N5Q3   B4LRG5   A0A1I8PYV3   A0A336LJY3   A0A3B0JGR3   A0A182FLN1   B4N062   Q29JX3   B4GL02   A0A1W4XLQ7   B4JEE6   A0A1W4UQI8   A0A1S3J8J2   A0A182QD81   A0A182PU86   W6JGW1   A0A151K3B2   A0A0L0CPP5   E2C2X0   A0A1A7X043   B4HY07   B4Q5A4   B3MKS6   B4NZY4   A0A1A8QX33   A0A182W2F8   A0A1A8LKD8   A0A1A8VHZ4   Q9VM60   A0A1B0F940   A0A1A8JLG5   A0A182RQZ9   A0A1B0C7Y4   A0A1A8BJY4   A0A182HNC4   A0A154PRE9   A0A182K614   A0A182N9L8   A0A182XC26   A0A1A8HF75   A0A182M851   A0A3B4A2Z9   A0A182VEA4   A0A1A9VIR3   A0A182UKI8   A0A151X3Q5   A0A1B0A6D8   Q7QGH1   F4WB70   A0A084VRL5   A0A0A1WKU0   A0A3Q4HJB6   A0A1A8FG05   A0A1B0GAR3   B3N671   A0A088ANV9   A0A195CN43   A0A1A9X0J6   K7J9J8   R7UQG6   A0A3P9BYS6   A0A0K8V9G6   A0A3B4YZA7   A0A0M4E937   A0A3P9N1N7   U5EXQ7   A0A3P8QMP1   A0A3Q2VEP8   A0A3B4F2V8   A0A3B4E151   Q7ZYP6   A0A3B4CDT0   A0A3P8UBQ0   A0A3Q1AUK7   A0A2I4D5F4   A0A3B3TZC2   F6XH58   A0A3Q2YM48  

Pubmed

19121390    26354079    22118469    23622113    18362917    19820115    + More
17510324    23537049    20920257    23761445    17994087    26483478    24845553    25315136    15632085    24567405    26108605    20798317    22936249    17550304    10731132    12537572    12537569    18327897    25463417    12364791    21719571    24438588    25830018    25186727    20075255    23254933    21196493    20431018   

EMBL

BABH01016366    ODYU01001443    SOQ37648.1    NWSH01003235    PCG66711.1    GDQN01001921    + More
JAT89133.1    KQ459252    KPJ02129.1    KQ461185    KPJ07487.1    AGBW02009812    OWR49862.1    GAIX01004171    JAA88389.1    KQ971319    EFA00312.1    NEVH01020944    PNF20404.1    LJIG01009595    KRT82765.1    CH477274    EAT45154.1    KB632169    ERL89430.1    ADMH02000225    ETN67308.1    CH933807    EDW12556.1    APGK01049519    KB741156    ENN73511.1    JXUM01086088    KQ563543    KXJ73685.1    KK852867    KDR14717.1    CH940649    EDW64635.1    UFQT01000039    SSX18504.1    OUUW01000006    SPP81547.1    CH963920    EDW77997.1    CH379062    EAL32838.1    CH479184    EDW37318.1    CH916368    EDW03666.1    AXCN02002036    AB734108    BAO48218.1    LKEY01056763    KYN50624.1    JRES01000080    KNC34348.1    GL452255    EFN77674.1    HADW01009918    SBP11318.1    CH480818    EDW51937.1    CM000361    CM002910    EDX04037.1    KMY88662.1    CH902620    EDV31607.1    CM000157    EDW87811.1    HAEH01013804    HAEI01016947    SBR98360.1    HAEF01006982    HAEF01016192    HAEG01009914    SBR44364.1    HAEJ01018730    SBS59187.1    AE014134    AY069585    HAEE01000144    SBR20160.1    JXJN01025925    HADZ01003563    HAEA01014057    SBP67504.1    APCN01001904    KQ435007    KZC13690.1    HAEC01013911    SBQ82128.1    AXCM01003888    KQ982557    KYQ55043.1    AAAB01008834    EAA05693.4    GL888057    EGI68577.1    ATLV01015746    KE525033    KFB40609.1    GBXI01014638    JAC99653.1    HAEB01010537    SBQ57064.1    CCAG010015502    CH954177    EDV59158.1    KQ977532    KYN02128.1    AAZX01002692    AMQN01006769    KB299094    ELU08435.1    GDHF01017109    JAI35205.1    CP012523    ALC38638.1    GANO01000827    JAB59044.1    BC042336    AAMC01103138    AAMC01103139   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000007266    + More
UP000235965    UP000192223    UP000008820    UP000030742    UP000000673    UP000009192    UP000019118    UP000075880    UP000069940    UP000249989    UP000027135    UP000095301    UP000008792    UP000095300    UP000268350    UP000069272    UP000007798    UP000001819    UP000008744    UP000001070    UP000192221    UP000085678    UP000075886    UP000075885    UP000078492    UP000037069    UP000008237    UP000001292    UP000000304    UP000007801    UP000002282    UP000075920    UP000000803    UP000092443    UP000075900    UP000092460    UP000075840    UP000076502    UP000075881    UP000075884    UP000076407    UP000075883    UP000261520    UP000075903    UP000078200    UP000075902    UP000075809    UP000092445    UP000007062    UP000007755    UP000030765    UP000261580    UP000092444    UP000008711    UP000005203    UP000078542    UP000091820    UP000002358    UP000014760    UP000265160    UP000261400    UP000092553    UP000242638    UP000265100    UP000264840    UP000261460    UP000261440    UP000265080    UP000257160    UP000192220    UP000261500    UP000008143    UP000264820   

PRIDE

H9JR76    Q9VM60    Q7ZYP6   

Pfam

PF09739   MCM_bind        + More
PF09445   Methyltransf_15

Interpro

IPR019140   MCM_complex-bd        + More
IPR029063   SAM-dependent_MTases       
IPR019012   RNA_cap_Gua-N2-MeTrfase       

SUPFAM

SSF53335   SSF53335       

ProteinModelPortal

H9JR76   A0A2H1V9Y4   A0A2A4J3Z2   A0A1E1WQ04   A0A194Q9P4   A0A194QPQ7   + More
A0A212F7Z6   S4PCJ5   D6WEZ4   A0A2J7PVP2   A0A1W4XKV9   A0A0T6B6P9   Q0IG57   A0A1S4F502   U4UHS8   W5JVF0   B4KJV3   N6TYT0   A0A182IP45   A0A182GT23   A0A067R5U4   A0A1I8N5Q3   B4LRG5   A0A1I8PYV3   A0A336LJY3   A0A3B0JGR3   A0A182FLN1   B4N062   Q29JX3   B4GL02   A0A1W4XLQ7   B4JEE6   A0A1W4UQI8   A0A1S3J8J2   A0A182QD81   A0A182PU86   W6JGW1   A0A151K3B2   A0A0L0CPP5   E2C2X0   A0A1A7X043   B4HY07   B4Q5A4   B3MKS6   B4NZY4   A0A1A8QX33   A0A182W2F8   A0A1A8LKD8   A0A1A8VHZ4   Q9VM60   A0A1B0F940   A0A1A8JLG5   A0A182RQZ9   A0A1B0C7Y4   A0A1A8BJY4   A0A182HNC4   A0A154PRE9   A0A182K614   A0A182N9L8   A0A182XC26   A0A1A8HF75   A0A182M851   A0A3B4A2Z9   A0A182VEA4   A0A1A9VIR3   A0A182UKI8   A0A151X3Q5   A0A1B0A6D8   Q7QGH1   F4WB70   A0A084VRL5   A0A0A1WKU0   A0A3Q4HJB6   A0A1A8FG05   A0A1B0GAR3   B3N671   A0A088ANV9   A0A195CN43   A0A1A9X0J6   K7J9J8   R7UQG6   A0A3P9BYS6   A0A0K8V9G6   A0A3B4YZA7   A0A0M4E937   A0A3P9N1N7   U5EXQ7   A0A3P8QMP1   A0A3Q2VEP8   A0A3B4F2V8   A0A3B4E151   Q7ZYP6   A0A3B4CDT0   A0A3P8UBQ0   A0A3Q1AUK7   A0A2I4D5F4   A0A3B3TZC2   F6XH58   A0A3Q2YM48  

KEGG

100286771    no KO assigned | (RefSeq) uncharacterized LOC100286771

GO

GO:0000790   GO:0003682   GO:0006261   GO:0001510   GO:0009452   GO:0008168   GO:0007049   GO:0051301   GO:0005634   GO:0006260   GO:0007062  

PANTHER

PTHR13489  

Subcellular location

Nucleus  

Length:

604

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01279

Exp number, first 60 AAs:

0.00159

Total prob of N-in:

0.00077

outside

1  -  604

 

 

Pi

19.863347

Theta

18.031825

Tajima's D

0.330104

CLR

13.734361

CSRT

0.479426028698565

Interpretation

Uncertain