Gene

KWMTBOMO06710

Annotation

PREDICTED:_meiosis-specific_with_OB_domain-containing_protein-like_isoform_X1_[Papilio_xuthus]

Location

Bomo_Chr11(-):12880063-12882019      View in EpiBrowser

Full name

Meiosis-specific with OB domain-containing protein      

Alternative Name

Protein expressed in male leptotene and zygotene spermatocytes 675

Location in the cell

Mitochondrial   Reliability : 1.096 PlasmaMembrane   Reliability : 1.418

CDS

ATGGCTGGAGTTCAAAAAGTTTGCCTTAATGCTTTAAATATTAACCAAAAAAATGCACTCATATTGGGTATCATAATAGCTAAAAATAGTCCTCGTACCATCAGTTCACGGAGAAAAAATGGGGAATCTAGAGCCGTTACATCTTTCACATTGAGAGATTCAGAAGTCGATACAATCAATATTGATGTGTGGGGTTCGGAATACTTTGTGTTTACTTTCTATGAACGTTTTCTCGTTGGTGACATTGTAGAAATTACTGCACCCAAGATATGCATTAAAACTGGTGAGAATGAAAATTTCAGACCTCAGGTATCGTCGCCATTCTACCTTTCAATAAACGAGGGCGCTTCAGACGTGAGTATACATGGGAGCGACATGCAAAGCTCTTATTTGCCACTCCTCCACATACCTTCAAAGCATTCATCTGCATACTATGGGCTCGCCGAAGTACTCAAGCTTCCAGAAGAAGCCAATAATGTTTACGTAGATCTCCTCGTTGTAGTAAAGAGTGTGATGTCCGCCAAGAAGATTAAAACTAAAACGGGTAGGTAA

Protein

MAGVQKVCLNALNINQKNALILGIIIAKNSPRTISSRRKNGESRAVTSFTLRDSEVDTINIDVWGSEYFVFTFYERFLVGDIVEITAPKICIKTGENENFRPQVSSPFYLSINEGASDVSIHGSDMQSSYLPLLHIPSKHSSAYYGLAEVLKLPEEANNVYVDLLVVVKSVMSAKKIKTKTGR

Description

Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.
Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro (By similarity).

Subunit

Component of a multiprotein complex with RPA2 and SPATA22.

Similarity

Belongs to the MEIOB family.

Keywords

Chromosome   Complete proteome   Cytoplasm   DNA-binding   Exonuclease   Hydrolase   Meiosis   Nuclease   Nucleus   Reference proteome  

Feature

chain  Meiosis-specific with OB domain-containing protein

Uniprot

A0A2A4K9P0   A0A3S2N735   A0A2H1X0P9   A0A212FGW8   E0VMV2   A0A067RAZ3   + More
A0A1B6J8E4   A0A1B6GAB0   J9LZH3   A0A2G8JNW5   A0A2J7QNF3   A0A0L7QVE7   A0A1B6DUZ9   A0A0C9S1K6   A0A2S2QF90   A0A3Q0JJ28   K1R358   A0A2L2Y5H5   A0A1S3H2H8   A0A151X5W4   S4R4D8   F4X4U2   A0A151HXY9   K7JB57   A0A195ES62   W4ZCJ6   A0A139WHN4   A0A158NWB9   A0A088A232   A0A026WGC1   A0A151IC15   E2BXI3   A0A2B4S3V5   A0A2A3EMR7   N6THQ7   U4UZC1   A0A1W4WL02   A0A1S4FPI7   Q16TL7   A0A1W4W9J8   A0A3M6UGG4   A7SE42   A0A154PTI4   F1R891   A0A2R8RX28   A0A3B3Y4K1   A0A087Y8K6   H1A0T8   A0A091RMT9   G1N1Q0   A0A093JBW6   A0A226PR39   A0A3Q0DA65   A0A0D2X3V5   A0A093I3P9   A0A099Z7D6   A0A226NM04   A0A091MT27   A0A1X7V6S8   H2LD88   A0A2I0LTJ9   A0A3P9K8V5   A0A3L8DF35   A0A3P9PNK7   V4B330   H0Z8N8   A0A087V608   A0A3P9JSE1   A0A3P9IKQ8   A0A091Q7K6   A0A091JWJ7   A0A1V4KU77   A0A094LAG8   A0A3Q4EHK6   A0A093F4D9   A0A093BWS4   A0A3Q0D9K0   A0A087RG57   A0A2T7PZI8   A0A091KUG4   A0A093Q6A2   A0A091N3B0   A0A091VB21   A0A3Q0GQK1   Q9D513   A0A315UX47   A0A3Q2GWW9   A0A091GPB1   A0A091S0W0   A0A151N1Z0   B0BMX9   A0A182MMM4   A0A091G592   A0A093CFG8   A0A151N203   A0A091EPH5   A0A1S3A200  

EC Number

3.1.-.-

Pubmed

22118469    20566863    24845553    29023486    22992520    26561354    + More
21719571    20075255    18362917    19820115    21347285    24508170    20798317    23537049    17510324    30382153    17615350    23594743    20360741    20838655    24621616    28071753    17554307    23371554    30249741    23254933    19468303    15489334    16141072    20339383    24240703    24068956    29703783    19892987    22293439   

EMBL

NWSH01000021    PCG80686.1    RSAL01004908    RVE40076.1    ODYU01012500    SOQ58847.1    + More
AGBW02008592    OWR52977.1    DS235327    EEB14708.1    KK852815    KDR15817.1    GECU01012264    JAS95442.1    GECZ01010403    JAS59366.1    ABLF02034942    MRZV01001510    MRZV01000594    PIK37395.1    PIK47227.1    NEVH01013195    PNF30117.1    KQ414727    KOC62456.1    GEDC01007806    JAS29492.1    GBYB01014661    JAG84428.1    GGMS01006669    MBY75872.1    JH818141    EKC28296.1    IAAA01005484    LAA02395.1    KQ982491    KYQ55757.1    GL888679    EGI58515.1    KQ976730    KYM76437.1    AAZX01001709    KQ981993    KYN31090.1    AAGJ04067656    AAGJ04067657    AAGJ04067658    AAGJ04067659    AAGJ04067660    AAGJ04067661    AAGJ04067662    KQ971343    KYB27483.1    ADTU01027851    KK107231    EZA55018.1    KQ978069    KYM97358.1    GL451254    EFN79631.1    LSMT01000215    PFX23202.1    KZ288215    PBC32562.1    APGK01037497    KB740948    ENN77338.1    KI207901    ERL95756.1    CH477645    EAT37860.1    RCHS01001596    RMX52716.1    DS469634    EDO38044.1    KQ435078    KZC14500.1    AL844587    CT009714    BX571974    AYCK01025999    ABQF01093989    KK705193    KFQ29817.1    KL205900    KFV76359.1    AWGT02000031    OXB81889.1    KE346368    KJE94969.1    KL214742    KFV61371.1    KL890356    KGL77676.1    MCFN01000008    OXB68796.1    KK515701    KFP64660.1    AKCR02000102    PKK20751.1    QOIP01000009    RLU19057.1    KB199676    ESP04648.1    ABQF01123810    KL481121    KFO08050.1    KK690018    KFQ16192.1    KK532117    KFP28333.1    LSYS01001700    OPJ87447.1    KL282045    KFZ67765.1    AC166102    KK616651    KFV49029.1    KL454366    KFV08140.1    KL226347    KFM12461.1    PZQS01000001    PVD38831.1    KK756928    KFP43647.1    KL672051    KFW84508.1    KL375416    KFP83442.1    KL410807    KFQ99929.1    BC119085    BC119087    AK015924    NHOQ01002507    PWA16148.1    KL507842    KFO85456.1    KK939084    KFQ49296.1    AKHW03004153    KYO30833.1    BC158604    AXCM01003863    KL447789    KFO77118.1    KL240541    KFV11719.1    KYO30831.1    KK718885    KFO58951.1   

Proteomes

UP000218220    UP000283053    UP000007151    UP000009046    UP000027135    UP000007819    + More
UP000230750    UP000235965    UP000053825    UP000079169    UP000005408    UP000085678    UP000075809    UP000245300    UP000007755    UP000078540    UP000002358    UP000078541    UP000007110    UP000007266    UP000005205    UP000005203    UP000053097    UP000078542    UP000008237    UP000225706    UP000242457    UP000019118    UP000030742    UP000192223    UP000008820    UP000275408    UP000001593    UP000076502    UP000000437    UP000261480    UP000028760    UP000007754    UP000001645    UP000053584    UP000198419    UP000189706    UP000008743    UP000053875    UP000053641    UP000198323    UP000007879    UP000001038    UP000053872    UP000265180    UP000279307    UP000242638    UP000030746    UP000265200    UP000190648    UP000000589    UP000053286    UP000245119    UP000053258    UP000053283    UP000189705    UP000002281    UP000050525    UP000002494    UP000075883    UP000053760    UP000052976    UP000079721   

PRIDE

Q9D513    B0BMX9   

Pfam

PF16900   REPA_OB_2        + More
PF17244   CDC24_OB3
PF03564   DUF1759

Interpro

IPR012340   NA-bd_OB-fold        + More
IPR031657   REPA_OB_2       
IPR035203   Cdc24_OB3       
IPR011989   ARM-like       
IPR016024   ARM-type_fold       
IPR005312   DUF1759       

SUPFAM

SSF50249   SSF50249        + More
SSF48371   SSF48371       

Gene 3D

1.25.10.10    

ProteinModelPortal

A0A2A4K9P0   A0A3S2N735   A0A2H1X0P9   A0A212FGW8   E0VMV2   A0A067RAZ3   + More
A0A1B6J8E4   A0A1B6GAB0   J9LZH3   A0A2G8JNW5   A0A2J7QNF3   A0A0L7QVE7   A0A1B6DUZ9   A0A0C9S1K6   A0A2S2QF90   A0A3Q0JJ28   K1R358   A0A2L2Y5H5   A0A1S3H2H8   A0A151X5W4   S4R4D8   F4X4U2   A0A151HXY9   K7JB57   A0A195ES62   W4ZCJ6   A0A139WHN4   A0A158NWB9   A0A088A232   A0A026WGC1   A0A151IC15   E2BXI3   A0A2B4S3V5   A0A2A3EMR7   N6THQ7   U4UZC1   A0A1W4WL02   A0A1S4FPI7   Q16TL7   A0A1W4W9J8   A0A3M6UGG4   A7SE42   A0A154PTI4   F1R891   A0A2R8RX28   A0A3B3Y4K1   A0A087Y8K6   H1A0T8   A0A091RMT9   G1N1Q0   A0A093JBW6   A0A226PR39   A0A3Q0DA65   A0A0D2X3V5   A0A093I3P9   A0A099Z7D6   A0A226NM04   A0A091MT27   A0A1X7V6S8   H2LD88   A0A2I0LTJ9   A0A3P9K8V5   A0A3L8DF35   A0A3P9PNK7   V4B330   H0Z8N8   A0A087V608   A0A3P9JSE1   A0A3P9IKQ8   A0A091Q7K6   A0A091JWJ7   A0A1V4KU77   A0A094LAG8   A0A3Q4EHK6   A0A093F4D9   A0A093BWS4   A0A3Q0D9K0   A0A087RG57   A0A2T7PZI8   A0A091KUG4   A0A093Q6A2   A0A091N3B0   A0A091VB21   A0A3Q0GQK1   Q9D513   A0A315UX47   A0A3Q2GWW9   A0A091GPB1   A0A091S0W0   A0A151N1Z0   B0BMX9   A0A182MMM4   A0A091G592   A0A093CFG8   A0A151N203   A0A091EPH5   A0A1S3A200  

KEGG

101745838    K22420 meiosis-specific with OB domain-containing protein [EC:3.1.-.-] | (RefSeq) meiosis-specific w

GO

GO:0008310   GO:0000712   GO:0003697   GO:0007141   GO:0007144   GO:0005737   GO:0009566   GO:0007129   GO:0003682   GO:0000724   GO:0007140   GO:0005694   GO:0005634  

Subcellular location

Cytoplasm  
Nucleus  
Chromosome  

Length:

183

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.12729

Exp number, first 60 AAs:

0.11635

Total prob of N-in:

0.27732

outside

1  -  183

 

 

Pi

226.068255

Theta

174.044471

Tajima's D

0.932092

CLR

0

CSRT

0.638518074096295

Interpretation

Uncertain