Gene

KWMTBOMO06665

Pre Gene Modal

BGIBMGA011712

Annotation

PREDICTED:_gamma-glutamyl_hydrolase_A-like_[Bombyx_mori]

Location

Bomo_Chr11(+):12377311-12384535      View in EpiBrowser

Full name

Folate gamma-glutamyl hydrolase      

Location in the cell

PlasmaMembrane   Reliability : 2.981

CDS

ATGAATATAGATGATGTGACACAATTTATGCGCGTAAGACAGAAAAGCATTGTAGTGTGCCTAGTTAGTGACTGTTTTAATCTTATAACAGCAATATTATTAAGGTGGCTCTCGTTCTCCGGAGACGATTGGCTTACGGTGATCACTATGAAGAGTGCATTGCTTTTGCTCTGGTTGTACGTTTTTCATTGCGAAGGCGCTGTGATAGTGGAAAGCAATGAGTACTCGGTCGTAAATGACAGACCTATAATCGGTGTACTTTCTCAAGAACAATCGTTTTACCTCCATGGAAAGTTCCCTGAAGAGAACTACACAAGCTACATTGCTTCTTCGTATGTCAAAGACATTGAGGCATCGGGAGCTCGTGTTGTGCCCATTCTGATCGGTAAAGACCGTTCGTATTATAAGGAGCTGATGAAGAAAATTAATGGAGTATTGATTCCCGGGGGAGCAACGTTCTTCAACCAATCCAATGGATACGCTGACGCCGGTCAACACATTTACGAGCTTGCTATAGAAATGAACGACGCCGGAGACTATTTCCCGATCTTCGGAACCTGTCTTGGTTTTGAGCTCCTCGTTATCTTGGCCTCAGGGCGGGGAAAGAAAGAAAATAGAATCACTTGTCACTCTTTTGGAAATCTGCCACTTGATTTTACTTCAGATTTTCGTTCGAGCAAAATGTTTCGTGAAGTACCGGAAGACGTTGCCGACATTTTGGCGAACCAGGACGTGACCATTAACGCTCATCAGTTCTGCATCGTGGATGAGAATCTGAAAGCATACAATCTGACCGATGACTGGCGTGTTACTTCACACTCGAATGACGAATACGGCGTTCAGTTCATTGCTACAATTGAACATACGAGATATCCGTTCTACGGAGTTCAGTTTCATCCCGAGAAGAACGCGTTCGAATGGAAACGCTCGAAGAACTATGCTCACTCTTTAGATTCAATTAAAGCCAATAGGTACTTCATGAATTTCTTCGTCAAAGAATGCAGGAAGAGCTCTCACACGTTTGTCAATCAGGCTGAAGAGAATCGATACGTTATCTACAATTACGAGCCCAAGTTCACGGGAGTGCTCGGTAGCGCTTTCCACCAGTGCTACTTCTTTGAGCCCAGAGGAATTGTTACAAAATAA

Protein

MNIDDVTQFMRVRQKSIVVCLVSDCFNLITAILLRWLSFSGDDWLTVITMKSALLLLWLYVFHCEGAVIVESNEYSVVNDRPIIGVLSQEQSFYLHGKFPEENYTSYIASSYVKDIEASGARVVPILIGKDRSYYKELMKKINGVLIPGGATFFNQSNGYADAGQHIYELAIEMNDAGDYFPIFGTCLGFELLVILASGRGKKENRITCHSFGNLPLDFTSDFRSSKMFREVPEDVADILANQDVTINAHQFCIVDENLKAYNLTDDWRVTSHSNDEYGVQFIATIEHTRYPFYGVQFHPEKNAFEWKRSKNYAHSLDSIKANRYFMNFFVKECRKSSHTFVNQAEENRYVIYNYEPKFTGVLGSAFHQCYFFEPRGIVTK

Catalytic Activity

(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)n + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate

Feature

chain  Folate gamma-glutamyl hydrolase

Uniprot

H9JQA6   A0A2A4K651   A0A2A4K5Q6   A0A2H1W7K8   A0A194Q1X9   A0A194RLE2   + More
A0A182VLR8   A0A182JSK8   A0A182U901   Q7Q531   A0A182X4Q2   A0A182I4Q0   A0A182LK55   A0A182TAU1   A0A182RZS0   A0A182YD44   A0A182LWW3   A0A182WKS7   A0A182PMI1   A0A1J1J329   A0A1B0CFY5   A0A1L8DZI9   A0A182FC96   A0A2M4BRZ2   A0A2M4BQZ0   A0A2M4BPZ8   A0A1L8DZY4   A0A2M3Z531   A0A2M3Z553   Q17PL9   A0A2M3Z4C0   Q17PL8   A0A1S4EVC9   A0A182Q613   A0A182JM97   A0A084WA72   A0A2M4ADJ8   A0A1Q3FJV7   A0A182NIQ7   W5JUI2   A0A2M4ACX3   Q17PM0   A0A2M4DMJ7   T1DRQ4   K7J848   A0A1W7R8D0   A0A182H562   T1DJR8   U5EYI6   A0A1A9UJ71   A0A1A9XJG8   A0A1L8EAP3   A0A1L8EAJ2   A0A1L8EAM4   A0A1L8EAS8   D3TRZ8   A0A1I8MXC9   A0A1I8P2L5   T1PC71   A0A1A9X0N4   A0A1B0FBN2   A0A336MIE1   A0A0C9QBC1   A0A0C9RQL8   B0WIK1   A0A336MUB4   A0A067R906   E2BIR5   E2A6W8   A0A0A1WFF4   E9IPM1   A0A034VBS1   A0A2J7RQZ5   A0A034VE23   A0A0L0CCZ4   W8B2C3   A0A2J7RQZ7   A0A0K8VJE0   A0A1Y1LSN8   A0A158P2V9   F4W5X6   B4QM92   A0A195BN60   B3M8Q2   A0A0N0BKL4   B4ITT8   B4PHM7   B4HJ38   Q8IQM9   A0A023EMF2   Q5BIC6   A0A0C9PI19   B3NI69   Q29EM3   A0A3L8DEY1   E0VGS7   A0A151XHG1   A0A195DFN9   A0A336MQ05  

EC Number

3.4.19.9

Pubmed

19121390    26354079    12364791    14747013    17210077    20966253    + More
25244985    17510324    24438588    20920257    23761445    20075255    26483478    24330624    20353571    25315136    24845553    20798317    25830018    21282665    25348373    26108605    24495485    28004739    21347285    21719571    17994087    22936249    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    24945155    15632085    30249741    20566863   

EMBL

BABH01011963    NWSH01000114    PCG79398.1    PCG79399.1    ODYU01006722    SOQ48822.1    + More
KQ459590    KPI97410.1    KQ460205    KPJ16801.1    AAAB01008960    EAA11416.4    APCN01002345    AXCM01005276    CVRI01000067    CRL06776.1    AJWK01010561    GFDF01002238    JAV11846.1    GGFJ01006706    MBW55847.1    GGFJ01006252    MBW55393.1    GGFJ01006016    MBW55157.1    GFDF01002239    JAV11845.1    GGFM01002863    MBW23614.1    GGFM01002898    MBW23649.1    CH477190    EAT48734.1    GGFM01002592    MBW23343.1    EAT48732.1    AXCN02000419    ATLV01022048    KE525327    KFB47116.1    GGFK01005528    MBW38849.1    GFDL01007134    JAV27911.1    ADMH02000332    ETN66928.1    GGFK01005313    MBW38634.1    EAT48733.1    GGFL01014573    MBW78751.1    GAMD01000545    JAB01046.1    GEHC01000236    JAV47409.1    JXUM01110868    JXUM01110869    KQ565451    KXJ70954.1    GALA01000096    JAA94756.1    GANO01000331    JAB59540.1    GFDG01003124    JAV15675.1    GFDG01003125    JAV15674.1    GFDG01003127    JAV15672.1    GFDG01003126    JAV15673.1    EZ424200    ADD20476.1    KA646361    AFP60990.1    CCAG010008961    UFQT01001324    SSX30036.1    GBYB01000544    JAG70311.1    GBYB01010780    JAG80547.1    DS231949    EDS28524.1    UFQT01002283    SSX33091.1    KK852621    KDR20013.1    GL448530    EFN84405.1    GL437203    EFN70834.1    GBXI01016558    GBXI01002823    JAC97733.1    JAD11469.1    GL764554    EFZ17480.1    GAKP01018230    GAKP01018226    GAKP01018224    JAC40726.1    NEVH01000613    PNF43259.1    GAKP01018228    JAC40724.1    JRES01000577    KNC30101.1    GAMC01011270    JAB95285.1    PNF43260.1    GDHF01023597    GDHF01013303    JAI28717.1    JAI39011.1    GEZM01047985    JAV76669.1    ADTU01007511    GL887695    EGI70452.1    CM000363    CM002912    EDX10661.1    KMY99973.1    KQ976432    KYM87465.1    CH902618    EDV40026.1    KQ435698    KOX80762.1    CH891731    EDW99801.1    CM000159    EDW95465.1    CH480815    EDW41694.1    AE014296    BT150130    AAN11765.1    AGO35569.1    GAPW01003106    JAC10492.1    BT021298    AAX33446.1    GBYB01000543    JAG70310.1    CH954178    EDV52225.1    CH379070    EAL30037.3    QOIP01000009    RLU18954.1    DS235151    EEB12583.1    KQ982130    KYQ59755.1    KQ980903    KYN11657.1    UFQS01001914    UFQT01001914    SSX12707.1    SSX32150.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000075903    UP000075881    + More
UP000075902    UP000007062    UP000076407    UP000075840    UP000075882    UP000075901    UP000075900    UP000076408    UP000075883    UP000075920    UP000075885    UP000183832    UP000092461    UP000069272    UP000008820    UP000075886    UP000075880    UP000030765    UP000075884    UP000000673    UP000002358    UP000069940    UP000249989    UP000078200    UP000092443    UP000095301    UP000095300    UP000091820    UP000092444    UP000002320    UP000027135    UP000008237    UP000000311    UP000235965    UP000037069    UP000005205    UP000007755    UP000000304    UP000078540    UP000007801    UP000053105    UP000002282    UP000001292    UP000000803    UP000008711    UP000001819    UP000279307    UP000009046    UP000075809    UP000078492   

PRIDE

H9JQA6    Q8IQM9    Q5BIC6   

Pfam

PF07722   Peptidase_C26        + More
PF07743   HSCB_C
PF05603   DUF775
PF00534   Glycos_transf_1

Interpro

IPR029062   Class_I_gatase-like        + More
IPR011697   Peptidase_C26       
IPR015527   Pept_C26_g-glut_hydrolase       
IPR004640   HscB       
IPR036386   HscB_C_sf       
IPR001623   DnaJ_domain       
IPR036869   J_dom_sf       
IPR009073   HscB_oligo_C       
IPR008493   DUF775       
IPR001296   Glyco_trans_1       
IPR026051   ALG1-like       

SUPFAM

SSF52317   SSF52317        + More
SSF46565   SSF46565       
SSF47144   SSF47144       

Gene 3D

3.40.50.880     1.10.287.110     1.20.1280.20    

CDD

cd06257  DnaJ

ProteinModelPortal

H9JQA6   A0A2A4K651   A0A2A4K5Q6   A0A2H1W7K8   A0A194Q1X9   A0A194RLE2   + More
A0A182VLR8   A0A182JSK8   A0A182U901   Q7Q531   A0A182X4Q2   A0A182I4Q0   A0A182LK55   A0A182TAU1   A0A182RZS0   A0A182YD44   A0A182LWW3   A0A182WKS7   A0A182PMI1   A0A1J1J329   A0A1B0CFY5   A0A1L8DZI9   A0A182FC96   A0A2M4BRZ2   A0A2M4BQZ0   A0A2M4BPZ8   A0A1L8DZY4   A0A2M3Z531   A0A2M3Z553   Q17PL9   A0A2M3Z4C0   Q17PL8   A0A1S4EVC9   A0A182Q613   A0A182JM97   A0A084WA72   A0A2M4ADJ8   A0A1Q3FJV7   A0A182NIQ7   W5JUI2   A0A2M4ACX3   Q17PM0   A0A2M4DMJ7   T1DRQ4   K7J848   A0A1W7R8D0   A0A182H562   T1DJR8   U5EYI6   A0A1A9UJ71   A0A1A9XJG8   A0A1L8EAP3   A0A1L8EAJ2   A0A1L8EAM4   A0A1L8EAS8   D3TRZ8   A0A1I8MXC9   A0A1I8P2L5   T1PC71   A0A1A9X0N4   A0A1B0FBN2   A0A336MIE1   A0A0C9QBC1   A0A0C9RQL8   B0WIK1   A0A336MUB4   A0A067R906   E2BIR5   E2A6W8   A0A0A1WFF4   E9IPM1   A0A034VBS1   A0A2J7RQZ5   A0A034VE23   A0A0L0CCZ4   W8B2C3   A0A2J7RQZ7   A0A0K8VJE0   A0A1Y1LSN8   A0A158P2V9   F4W5X6   B4QM92   A0A195BN60   B3M8Q2   A0A0N0BKL4   B4ITT8   B4PHM7   B4HJ38   Q8IQM9   A0A023EMF2   Q5BIC6   A0A0C9PI19   B3NI69   Q29EM3   A0A3L8DEY1   E0VGS7   A0A151XHG1   A0A195DFN9   A0A336MQ05  

PDB

4L7Q     E-value=1.34905e-66,     Score=642

KEGG

101736547    K01307 gamma-glutamyl hydrolase [EC:3.4.19.9] | (RefSeq) gamma-glutamyl hydrolase A-like

PATHWAY

00790    Folate biosynthesis - Bombyx mori (domestic silkworm)

GO

GO:0034722   GO:0046900   GO:0005773   GO:0016021   GO:0001671   GO:0051087   GO:0051259   GO:0097428   GO:0006541   GO:0016787   GO:0003824   GO:0008242   GO:0016705   GO:0020037   GO:0006811   GO:0016020   GO:0005634   GO:0006260  

PANTHER

PTHR11315   PTHR13036  

Length:

381

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

68.7877500000001

Exp number, first 60 AAs:

36.35208

Total prob of N-in:

0.98232

POSSIBLE N-term signal

sequence

inside

1  -  16

TMhelix

17  -  39

outside

40  -  381

 

 

Pi

23.498825

Theta

18.038173

Tajima's D

0.552247

CLR

1.212221

CSRT

0.541572921353932

Interpretation

Uncertain