Gene

KWMTBOMO06657  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011774

Annotation

PREDICTED:_purine_nucleoside_phosphorylase-like_isoform_X2_[Amyelois_transitella]

Location

Bomo_Chr11(-):12268958-12282581      View in EpiBrowser

Full name

Purine nucleoside phosphorylase      

Alternative Name

Inosine-guanosine phosphorylase

Location in the cell

Cytoplasmic   Reliability : 3.355

CDS

ATGGCACCTATAAACGCGAACGATATCGTGGAGAAAAATTGTTTGGTCACGCAGAAGGTCCTGCCGGAAATCGGATCTGATTGTAATGGAAATGAAAAAACTGGATATTCTTATGAAACATTAGTGGAGACCGCAAATTTCTTGCTGTCGAGAATATCAGAGAAACCGAACATTGGGATCATTTGCGGCTCTGGGATGGGTTCACTAGCAGAAAGTATAACAGACGGCGTAAGAATACCATACGAAGATATTCCAAACTTTCCCATAAGCACAGTGGAGGGTCATCATGGTCAGCTTGTTTTCGGTCACATAGAAGGAGTGTCCGTCGTTGCTATGCAGGGCCGTTTTCATTACTACGAAGGATATCCACTGTGGAAGTGTTGTCTACCAGTGCGAGTGATGAAACTGTTGGGAGTGAAAATTTTAATAGCGACTAACGCTGCAGGCGGCCTTAACCCTAACTACAAAATTGGTGATCTGATGATTGTAAGAGACCACATCAACATGATGGGTTTTGCTGGAAACAATCCTTTGCATGGACCCAATGACGAGAGGTTTGGACCTAGATTCCCCCCTATGAACAAAGCCTATAATTATGAATTTAGAAAAATTGCTAAAGAGGTTGCGAAGGAATTAAACATCGATCATATTGTAAGGGAAGGAGTTTATACATGTTTGGGCGGTCCAAATTTCGAGACAGTCGCCGAATTGAATATGTTAAAGATGGTTGGAGTAGACGCTGTTGGCATGTCTACTGTTCACGAGGTTATCACAGCTAGACACTGCGACATTAAAGTATTCGGATTATCTCTGATTACGAATGAATGCATTACTAATTACGATCAAGATGCAGAAGCTAATCACGAGGAAGTTCTTGACGTAGGCCGTATGAGGCAGGAAATGCTCCGAAAATATGTATCCTGTCTTGTTAAGAAATTCTCACAGGCCGACCCTGATGCACCATGA

Protein

MAPINANDIVEKNCLVTQKVLPEIGSDCNGNEKTGYSYETLVETANFLLSRISEKPNIGIICGSGMGSLAESITDGVRIPYEDIPNFPISTVEGHHGQLVFGHIEGVSVVAMQGRFHYYEGYPLWKCCLPVRVMKLLGVKILIATNAAGGLNPNYKIGDLMIVRDHINMMGFAGNNPLHGPNDERFGPRFPPMNKAYNYEFRKIAKEVAKELNIDHIVREGVYTCLGGPNFETVAELNMLKMVGVDAVGMSTVHEVITARHCDIKVFGLSLITNECITNYDQDAEANHEEVLDVGRMRQEMLRKYVSCLVKKFSQADPDAP

Description

The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

Catalytic Activity

a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate

Similarity

Belongs to the PNP/MTAP phosphorylase family.

Uniprot

H9JQG8   A0A2A4K6V6   A0A3S2L924   A0A194QUB6   I4DJX3   A0A212FG34   + More
A0A2H1WEJ7   A0A194PXB1   I4DN26   F4X5C6   A0A151IRC0   A0A151WRP6   A0A151JXW1   A0A026WGL7   A0A336MF31   A0A2A3EEE2   V9ID02   V5G3C0   D6WHJ8   E2A5F2   A0A0C9QZ53   A0A1Y1MAZ9   V9IB69   V5I8X0   A0A088ARK6   A0A158NMI3   A0A195CVN9   A0A195AZQ9   A0A1Y1MDD8   A0A0M9A8P0   A0A1I8MDJ9   A0A0L0CHI9   A0A1I8MDK1   A0A1I8MDK5   T1PEF0   A0A1L8EFX7   A0A0A1WFJ0   W8C2C0   A0A1L8EFV6   A0A1L8E9B1   W8BG08   A0A0A1XDW8   A0A1I8PPA7   A0A3Q0IZV9   A0A2J7QGQ8   A0A1B6FLG7   A0A1A9XPE4   A0A0K8W5M4   K7IM21   A0A1A9VN56   A0A1A9WC80   D3TLL2   A0A034VEC1   A0A0K8V1L9   A0A1J1IK46   A0A034VGE2   A0A1B0AQ94   A0A232EJE3   A0A0K8V0D3   A0A2J7QGQ4   A0A1A9ZML4   A0A0K8V931   A0A023GHV8   A0A154P2N4   A0A1B6GSG4   N6U0W3   T1GD09   A0A1E1XFC6   A0A224Z2T0   G3MGH6   W5JNR5   A0A131YZ73   A0A067QW09   A0A224YXB2   A0A023FYA5   A0A131YDI9   T1J2B2   A0A2M4CME6   A0A2M4CMC9   A0A131XMM8   A0A0L7RIS9   A0A023FJU0   A0A2M4A309   A0A2M4A2J4   A0A3R7M3L2   U5EV37   A0A2M4BSI9   A0A0P4W8N2   A0A0N7ZCN7   A0A0P4WGT2   A0A2M3Z5F4   A0A2M4BW19   A0A084WA99   A0A0P5KMY5   A0A1Q3FGB9   A0A1Q3FGE3   A0A0N8ATM5   A0A0P5RJ47   A0A0P5JKK0   E9GU60  

EC Number

2.4.2.1

Pubmed

19121390    26354079    22651552    22118469    21719571    24508170    + More
30249741    18362917    19820115    20798317    28004739    21347285    25315136    26108605    25830018    24495485    20075255    20353571    25348373    28648823    23537049    28503490    28797301    22216098    20920257    23761445    26830274    24845553    28049606    24438588    21292972   

EMBL

BABH01011972    BABH01011973    BABH01011974    NWSH01000114    PCG79402.1    RSAL01000448    + More
RVE41679.1    KQ461190    KPJ07146.1    AK401591    BAM18213.1    AGBW02008724    OWR52690.1    ODYU01008119    SOQ51447.1    KQ459590    KPI97399.1    AK402694    BAM19316.1    GL888711    EGI58340.1    KQ981130    KYN09268.1    KQ982797    KYQ50582.1    KQ981550    KYN40023.1    KK107238    QOIP01000007    EZA54836.1    RLU20810.1    UFQT01001029    UFQT01002424    SSX28540.1    SSX33425.1    KZ288282    PBC29589.1    JR038612    AEY58341.1    GALX01003951    JAB64515.1    KQ971331    EFA01001.1    GL436926    EFN71333.1    GBYB01001005    JAG70772.1    GEZM01036044    JAV83009.1    JR038611    AEY58340.1    GALX01003950    JAB64516.1    ADTU01020586    ADTU01020587    ADTU01020588    KQ977231    KYN04741.1    KQ976697    KYM77520.1    GEZM01036045    JAV83008.1    KQ435726    KOX78203.1    JRES01000390    KNC31720.1    KA646495    AFP61124.1    GFDG01001274    JAV17525.1    GBXI01017114    GBXI01010393    JAC97177.1    JAD03899.1    GAMC01010671    JAB95884.1    GFDG01001273    JAV17526.1    GFDG01003613    JAV15186.1    GAMC01010672    JAB95883.1    GBXI01005634    JAD08658.1    NEVH01014359    PNF27771.1    GECZ01018750    JAS51019.1    GDHF01005893    GDHF01002942    JAI46421.1    JAI49372.1    CCAG010019517    CCAG010019518    EZ422314    ADD18590.1    GAKP01018108    JAC40844.1    GDHF01019510    JAI32804.1    CVRI01000050    CRK99446.1    GAKP01018107    JAC40845.1    JXJN01001758    NNAY01004028    OXU18474.1    GDHF01020076    JAI32238.1    PNF27772.1    GDHF01016932    JAI35382.1    GBBM01001916    JAC33502.1    KQ434806    KZC06117.1    GECZ01004399    JAS65370.1    APGK01053843    KB741237    ENN72187.1    CAQQ02024629    CAQQ02024630    CAQQ02024631    CAQQ02024632    GFAC01001228    JAT97960.1    GFPF01011123    MAA22269.1    JO840977    AEO32594.1    ADMH02000830    ETN64943.1    GEDV01004705    JAP83852.1    KK852879    KDR14468.1    GFPF01011122    MAA22268.1    GBBL01001592    JAC25728.1    GEDV01011939    JAP76618.1    JH431796    GGFL01002334    MBW66512.1    GGFL01002265    MBW66443.1    GEFH01000178    JAP68403.1    KQ414584    KOC70646.1    GBBK01003167    JAC21315.1    GGFK01001707    MBW35028.1    GGFK01001641    MBW34962.1    QCYY01002961    ROT66297.1    GANO01002043    JAB57828.1    GGFJ01006904    MBW56045.1    GDRN01063561    JAI64958.1    GDRN01063559    JAI64960.1    GDRN01063560    JAI64959.1    GGFM01002984    MBW23735.1    GGFJ01008118    MBW57259.1    ATLV01022056    KE525327    KFB47143.1    GDIQ01189274    JAK62451.1    GFDL01008448    JAV26597.1    GFDL01008430    JAV26615.1    GDIQ01244059    JAK07666.1    GDIQ01186321    GDIQ01119202    GDIP01116511    LRGB01002384    JAL32524.1    JAL87203.1    KZS07994.1    GDIQ01201776    GDIQ01189275    JAK49949.1    GL732565    EFX76980.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053240    UP000007151    UP000053268    + More
UP000007755    UP000078492    UP000075809    UP000078541    UP000053097    UP000279307    UP000242457    UP000007266    UP000000311    UP000005203    UP000005205    UP000078542    UP000078540    UP000053105    UP000095301    UP000037069    UP000095300    UP000079169    UP000235965    UP000092443    UP000002358    UP000078200    UP000091820    UP000092444    UP000183832    UP000092460    UP000215335    UP000092445    UP000076502    UP000019118    UP000015102    UP000000673    UP000027135    UP000053825    UP000283509    UP000030765    UP000076858    UP000000305   

PRIDE

H9JQG8   

Pfam

PF01048   PNP_UDP_1        + More
PF00009   GTP_EFTU

Interpro

IPR011270   Pur_Nuc_Pase_Ino/Guo-sp        + More
IPR035994   Nucleoside_phosphorylase_sf       
IPR000845   Nucleoside_phosphorylase_d       
IPR011268   Purine_phosphorylase       
IPR018099   Purine_phosphorylase-2_CS       
IPR000795   TF_GTP-bd_dom       
IPR027417   P-loop_NTPase       

SUPFAM

SSF53167   SSF53167        + More
SSF52540   SSF52540       

Gene 3D

3.40.50.1580    

ProteinModelPortal

H9JQG8   A0A2A4K6V6   A0A3S2L924   A0A194QUB6   I4DJX3   A0A212FG34   + More
A0A2H1WEJ7   A0A194PXB1   I4DN26   F4X5C6   A0A151IRC0   A0A151WRP6   A0A151JXW1   A0A026WGL7   A0A336MF31   A0A2A3EEE2   V9ID02   V5G3C0   D6WHJ8   E2A5F2   A0A0C9QZ53   A0A1Y1MAZ9   V9IB69   V5I8X0   A0A088ARK6   A0A158NMI3   A0A195CVN9   A0A195AZQ9   A0A1Y1MDD8   A0A0M9A8P0   A0A1I8MDJ9   A0A0L0CHI9   A0A1I8MDK1   A0A1I8MDK5   T1PEF0   A0A1L8EFX7   A0A0A1WFJ0   W8C2C0   A0A1L8EFV6   A0A1L8E9B1   W8BG08   A0A0A1XDW8   A0A1I8PPA7   A0A3Q0IZV9   A0A2J7QGQ8   A0A1B6FLG7   A0A1A9XPE4   A0A0K8W5M4   K7IM21   A0A1A9VN56   A0A1A9WC80   D3TLL2   A0A034VEC1   A0A0K8V1L9   A0A1J1IK46   A0A034VGE2   A0A1B0AQ94   A0A232EJE3   A0A0K8V0D3   A0A2J7QGQ4   A0A1A9ZML4   A0A0K8V931   A0A023GHV8   A0A154P2N4   A0A1B6GSG4   N6U0W3   T1GD09   A0A1E1XFC6   A0A224Z2T0   G3MGH6   W5JNR5   A0A131YZ73   A0A067QW09   A0A224YXB2   A0A023FYA5   A0A131YDI9   T1J2B2   A0A2M4CME6   A0A2M4CMC9   A0A131XMM8   A0A0L7RIS9   A0A023FJU0   A0A2M4A309   A0A2M4A2J4   A0A3R7M3L2   U5EV37   A0A2M4BSI9   A0A0P4W8N2   A0A0N7ZCN7   A0A0P4WGT2   A0A2M3Z5F4   A0A2M4BW19   A0A084WA99   A0A0P5KMY5   A0A1Q3FGB9   A0A1Q3FGE3   A0A0N8ATM5   A0A0P5RJ47   A0A0P5JKK0   E9GU60  

PDB

2P4S     E-value=7.95132e-101,     Score=936

KEGG

101736818    K03783 purine-nucleoside phosphorylase [EC:2.4.2.1] | (RefSeq) purine nucleoside phosphorylase-like

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
00240    Pyrimidine metabolism - Bombyx mori (domestic silkworm)
00760    Nicotinate and nicotinamide metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0004731   GO:0009116   GO:0005737   GO:0016021   GO:0006139   GO:0003824   GO:0006812   GO:0015299   GO:0006811   GO:0016020   GO:0005634   GO:0006260  

PANTHER

PTHR11904  

Length:

321

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.09569

Exp number, first 60 AAs:

0.00064

Total prob of N-in:

0.02429

outside

1  -  321

 

 

Pi

283.400321

Theta

190.576673

Tajima's D

1.663534

CLR

0.304513

CSRT

0.826308684565772

Interpretation

Uncertain