Gene

KWMTBOMO06655

Pre Gene Modal

BGIBMGA011775

Annotation

PREDICTED:_tRNA-splicing_endonuclease_subunit_Sen34_[Papilio_xuthus]

Location

Bomo_Chr11(-):12253408-12258201      View in EpiBrowser

Full name

tRNA-splicing endonuclease subunit Sen34      

Location in the cell

Cytoplasmic   Reliability : 2.107 Extracellular   Reliability : 1.467

CDS

ATGATTTCTTGGATCTTTGCAGGGCTTCCGATTGCATTATCTTCTGAAGAAACAGCATTATTGGTTGAAAAGAGGATATGTGAACTTCATGAAATGCCAGCTGAATTTTGTAAATATGAACCAACAGAAAAGGATAAAGAATTAATGGAAGAATTTTTAAAAAAAGTACTTGAACAACAAGCATCAGCATTAAAGAAACGCAAAATAGAACAATTATCACAAAAGATTGATATCATTGTGGCTGGGAAAAAGAAAAACCTCATAAATAAAGGGATGTCTGATGCAAATATTGATAAAGATGCAATGTTAGAAGAAGAAATAAAAAGAATACAAGATTTAGATCCAGACCACACTTTAGTACAACTTCCACAAGAAATGTATAGAAATATAGAAACCAGTCCAGTAGGTTTGGATGTATTAAGACCAAATATTTTGGAAGGAGATGGTGCCGTTAAGTATTCTATATTCAAAGACTTATGGGAGAAAGGATATTATGTTACCAGTGGATCAAAATTTGGATGTGATTATCTTATATACCCAGGCGATCCTGTGCAGTTTCATGCCTCGCATATGGTTCGATGCGTTTGTAATCAAGAAAATGTTTTCCACCCTAAAAGCTTAGTGGCGTTCGGCAGATTATCAGTGGCCGTCAATAAGTATGCAGTTTTTGCATATAGAACTCAGTGTGCGCGAATTGCATATCAAACTCTGCAATGGCATGACAGCATGGATTCTTGA

Protein

MISWIFAGLPIALSSEETALLVEKRICELHEMPAEFCKYEPTEKDKELMEEFLKKVLEQQASALKKRKIEQLSQKIDIIVAGKKKNLINKGMSDANIDKDAMLEEEIKRIQDLDPDHTLVQLPQEMYRNIETSPVGLDVLRPNILEGDGAVKYSIFKDLWEKGYYVTSGSKFGCDYLIYPGDPVQFHASHMVRCVCNQENVFHPKSLVAFGRLSVAVNKYAVFAYRTQCARIAYQTLQWHDSMDS

Description

Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

Catalytic Activity

PretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.

Similarity

Belongs to the tRNA-intron endonuclease family.

Uniprot

H9JQG9   A0A2H1WEF9   A0A2A4K666   A0A194PVP3   A0A1E1W6P0   A0A194QNP7   + More
S4PDN4   A0A3S2N524   A0A0L7LV47   A0A067QI60   A0A1B0DJ44   B0X2T9   B4QK26   A0A1W4XHE4   B4HHS9   A0A2J7RA58   A0A2J7RA46   A0A1B0CSR0   A0A026W1B4   A0A1Q3F5L3   A0A1A9VFD4   Q0E8E7   D2NUI2   G4LU02   A0A1B0G9Y8   A0A1B0A2A3   A0A182GG98   A0A0M4EM16   E2AUD7   A0A182G1R5   A0A1S4FJZ8   A0A2A3E1E7   A0A088AVZ8   A0A1B6CWN3   A0A1I8P9N7   A0A1I8P9W0   A0A1B0AVW0   Q16YD2   B5DQS3   A0A154PDJ4   A0A182WDX8   B3MAW2   A0A1W4UKM1   B4PIG6   A0A1A9XR90   A0A1W4U8S9   E9J1N6   A0A182IQJ8   A0A232EU37   A0A0N8B842   A0A0P5Y840   A0A0P6FM94   A0A158P3X0   A0A1I8MDV3   A0A0Q9XG26   W8BUP8   A0A182TA15   B4KVK9   A0A195BKM6   D6WIR4   K7IQN6   A0A182Q2X7   B4J3T7   B4LF54   A0NGQ6   A0A034WRL9   A0A0K8W0B3   A0A151J8Z8   A0A182L517   E0VW20   A0A3B0J386   A0A195CNX8   A0A182HHI2   A0A182MHV5   A0A182UAP6   A0A151WVB4   A0A0L0CED2   A0A182VGL5   A0A182RRZ6   A0A084WIP1   F4WKV0   A0A182XTJ4   A0A182JRB0   A0A0P6HN96   E9FVZ2   A0A0P5LIF7   A0A182N2W8   B3ND56   A0A0P6AJ82   A0A1Y1LF38   A0A0A1WV44   A0A1B6M6M6   A0A0A9ZH52   A0A0K8SKM5   A0A2T7PFP2   A0A2M4AYD3   A0A2M4CUJ4   A0A2K6VAZ7   A0A0L7QPN5  

EC Number

4.6.1.16

Pubmed

19121390    26354079    23622113    26227816    24845553    17994087    + More
22936249    24508170    30249741    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26483478    20798317    17510324    15632085    17550304    21282665    28648823    21347285    25315136    24495485    18057021    18362917    19820115    20075255    12364791    14747013    17210077    25348373    20966253    20566863    26108605    24438588    21719571    21292972    28004739    25830018    25401762    26823975    20920257   

EMBL

BABH01011976    ODYU01008119    SOQ51449.1    NWSH01000114    PCG79404.1    KQ459590    + More
KPI97397.1    GDQN01008392    JAT82662.1    KQ461190    KPJ07148.1    GAIX01003601    JAA88959.1    RSAL01000448    RVE41681.1    JTDY01000028    KOB79332.1    KK853353    KDR08208.1    AJVK01006199    DS232298    EDS39413.1    CM000363    CM002912    EDX10464.1    KMY99621.1    CH480815    EDW41494.1    NEVH01006578    PNF37704.1    PNF37705.1    AJWK01026423    KK107570    QOIP01000005    EZA48854.1    RLU23094.1    GFDL01012199    JAV22846.1    AE014296    ABI31252.2    BT120125    ADB46406.1    BT132632    AEQ05528.1    CCAG010008280    JXUM01061327    KQ562145    KXJ76577.1    CP012525    ALC44610.1    GL442815    EFN62994.1    JXUM01137733    KQ568620    KXJ68944.1    KZ288451    PBC25573.1    GEDC01019705    JAS17593.1    JXJN01004400    CH477518    EAT39638.1    CH379069    EDY73389.2    KQ434878    KZC09901.1    CH902618    EDV39196.1    CM000159    EDW94523.1    GL767674    EFZ13246.1    NNAY01002176    OXU21868.1    GDIP01146506    GDIQ01203523    LRGB01000024    JAJ76896.1    JAK48202.1    KZS21683.1    GDIP01061564    JAM42151.1    GDIQ01048233    JAN46504.1    ADTU01008608    CH933809    KRG06649.1    GAMC01001475    JAC05081.1    EDW19480.1    KQ976453    KYM85324.1    KQ971321    EEZ99511.2    AXCN02001090    CH916366    EDV97318.1    CH940647    EDW70242.2    AAAB01008986    EAU75852.2    GAKP01001678    JAC57274.1    GDHF01007773    JAI44541.1    KQ979480    KYN21264.1    AAZO01005737    DS235816    EEB17576.1    OUUW01000002    SPP76054.1    KQ977513    KYN02182.1    APCN01002416    AXCM01009764    KQ982708    KYQ51803.1    JRES01000502    KNC30606.1    ATLV01023941    KE525347    KFB50085.1    GL888206    EGI65192.1    GDIQ01016728    JAN78009.1    GL732525    EFX88635.1    GDIQ01171333    JAK80392.1    CH954178    EDV51778.1    GDIP01030112    JAM73603.1    GEZM01062527    GEZM01062524    GEZM01062523    GEZM01062520    JAV69627.1    GBXI01012014    JAD02278.1    GEBQ01008409    JAT31568.1    GBHO01000591    JAG43013.1    GBRD01011958    GDHC01002291    JAG53866.1    JAQ16338.1    PZQS01000004    PVD32238.1    GGFK01012401    MBW45722.1    GGFL01004812    MBW68990.1    KQ414815    KOC60519.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000283053    UP000037510    + More
UP000027135    UP000092462    UP000002320    UP000000304    UP000192223    UP000001292    UP000235965    UP000092461    UP000053097    UP000279307    UP000078200    UP000000803    UP000092444    UP000092445    UP000069940    UP000249989    UP000092553    UP000000311    UP000242457    UP000005203    UP000095300    UP000092460    UP000008820    UP000001819    UP000076502    UP000075920    UP000007801    UP000192221    UP000002282    UP000092443    UP000075880    UP000215335    UP000076858    UP000005205    UP000095301    UP000009192    UP000075901    UP000078540    UP000007266    UP000002358    UP000075886    UP000001070    UP000008792    UP000007062    UP000078492    UP000075882    UP000009046    UP000268350    UP000078542    UP000075840    UP000075883    UP000075902    UP000075809    UP000037069    UP000075903    UP000075900    UP000030765    UP000007755    UP000076407    UP000075881    UP000000305    UP000075884    UP000008711    UP000245119    UP000053825   

PRIDE

H9JQG9    Q0E8E7   

Pfam

PF01974   tRNA_int_endo

Interpro

IPR011856   tRNA_endonuc-like_dom_sf        + More
IPR036167   tRNA_intron_Endo_cat-like_sf       
IPR006677   tRNA_intron_Endonuc_cat-like       
IPR016690   tRNA_splic_SEN34       
IPR006676   tRNA_splic       

SUPFAM

SSF53032   SSF53032       

Gene 3D

3.40.1350.10    

ProteinModelPortal

H9JQG9   A0A2H1WEF9   A0A2A4K666   A0A194PVP3   A0A1E1W6P0   A0A194QNP7   + More
S4PDN4   A0A3S2N524   A0A0L7LV47   A0A067QI60   A0A1B0DJ44   B0X2T9   B4QK26   A0A1W4XHE4   B4HHS9   A0A2J7RA58   A0A2J7RA46   A0A1B0CSR0   A0A026W1B4   A0A1Q3F5L3   A0A1A9VFD4   Q0E8E7   D2NUI2   G4LU02   A0A1B0G9Y8   A0A1B0A2A3   A0A182GG98   A0A0M4EM16   E2AUD7   A0A182G1R5   A0A1S4FJZ8   A0A2A3E1E7   A0A088AVZ8   A0A1B6CWN3   A0A1I8P9N7   A0A1I8P9W0   A0A1B0AVW0   Q16YD2   B5DQS3   A0A154PDJ4   A0A182WDX8   B3MAW2   A0A1W4UKM1   B4PIG6   A0A1A9XR90   A0A1W4U8S9   E9J1N6   A0A182IQJ8   A0A232EU37   A0A0N8B842   A0A0P5Y840   A0A0P6FM94   A0A158P3X0   A0A1I8MDV3   A0A0Q9XG26   W8BUP8   A0A182TA15   B4KVK9   A0A195BKM6   D6WIR4   K7IQN6   A0A182Q2X7   B4J3T7   B4LF54   A0NGQ6   A0A034WRL9   A0A0K8W0B3   A0A151J8Z8   A0A182L517   E0VW20   A0A3B0J386   A0A195CNX8   A0A182HHI2   A0A182MHV5   A0A182UAP6   A0A151WVB4   A0A0L0CED2   A0A182VGL5   A0A182RRZ6   A0A084WIP1   F4WKV0   A0A182XTJ4   A0A182JRB0   A0A0P6HN96   E9FVZ2   A0A0P5LIF7   A0A182N2W8   B3ND56   A0A0P6AJ82   A0A1Y1LF38   A0A0A1WV44   A0A1B6M6M6   A0A0A9ZH52   A0A0K8SKM5   A0A2T7PFP2   A0A2M4AYD3   A0A2M4CUJ4   A0A2K6VAZ7   A0A0L7QPN5  

PDB

3P1Z     E-value=7.09754e-09,     Score=142

KEGG

101737033    K15323 tRNA-splicing endonuclease subunit Sen34 [EC:4.6.1.16] | (RefSeq) tRNA-splicing endonuclease

GO

GO:0000213   GO:0003676   GO:0000214   GO:0000379   GO:0016829   GO:0016021   GO:0006388   GO:0004518   GO:0006812   GO:0015299   GO:0006811   GO:0016020   GO:0005634   GO:0006260  

Length:

245

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.05518

Exp number, first 60 AAs:

0.00723

Total prob of N-in:

0.00713

outside

1  -  245

 

 

Pi

207.148638

Theta

166.683309

Tajima's D

0.693257

CLR

0

CSRT

0.572121393930303

Interpretation

Uncertain