Gene

KWMTBOMO06642

Pre Gene Modal

BGIBMGA011700

Annotation

PREDICTED:_sodium/hydrogen_exchanger_8_[Papilio_xuthus]

Location

Bomo_Chr11(+):12018032-12025549      View in EpiBrowser

Full name

Sodium/hydrogen exchanger      

Location in the cell

PlasmaMembrane   Reliability : 4.968

CDS

ATGAATGTTAATCAAACAGTCGATTCAACAACTCCAAGTTCAACCGAAAAATCGAATATAGTTTACGAAATAGGACCATCAAATTCTTCAATACTGGCAGTAGTTCAAGTTAATGCTTCGGCTGCGACACCCAATGCCTCTGTTAATCCATCAGACGCTGCTCCTCTTCCAGAAAAAAGCTCAGCTGAAGATGAACATAATAGCTCAATGGCAATATTTTTCGTACTCTGTATTTTGGCCTTAGGTATACTGTTAATACATTTAATGTTACAAACAGGATTTTCTTATCTCCCTGAAAGTGTGGTTATAGTATTTCTTGGTGCTCTCATTGGAATGATAATAAATCTTATGTCGATAAAAAATATTGCCAATTGGAGAAAGGAAGAAGCATTTTCACCAACAGCTTTCTTTTTAGTGTTGCTACCACCCATCATATTTGAATCGGGTTATAATCTCCACAAAGGCAACTTTTTTCAAAATATTGGTTCAATATTGTTATTTGCTATCGTAGGAACTGCAATATCAGCATTTGTAATTGGAGCTGGTATCTACTTATTGGGTTTGGCTCAGGTTGTATATAAACTTAGCTTTGTTGAGTCATTTGCTTTTGGATCCCTGATATCTGCTGTGGATCCAGTCGCCACTGTGGCTATATTTCACGCTCTAGATGTTGACCCAGTTCTCAACATGTTGGTATTTGGGGAGAGTATATTAAATGATGCTGTGGCTATTGTGTTGACAACAGCCGTTCTGGATTCCAATGACCCTTTCATGTCTACAGGAGAGGCAATTCTCTCTGCAATTAATCGATTTTGGTTAATGTTCTTTGCATCAGCTGGCATTGGTGTACTTTTTGCACTTGTGAGTGCCTTACTCTTGAAACATGTTGATCTCAGAAAGAATCCATCTCTTGAGTTTGGAATGATGTTGGTATTCACATATGCTCCTTATGTGTTAGCTGAAGGCATTCACTTGTCAGGGATTATGGCTATACTGTTTTGTGGTATTGTGATGTCTCATTACACTCATTTTAATTTATCCACAATTACTCAAGTTACAATGCAACAAACAATGAGAACTCTTGCATTCATCGCGGAAACATGTGTTTTTGCATATTTAGGACTTGCTCTATTCAGTTTCAGACATCGCGTCGAACCTGCACTGGTAGTCTGGAGTATAGTAATGTGTCTCCTTGGCAGAGCAGCTAATATATTCCCTTTGGCACTGCTTTGCAACAAATTTCGAGAACACAAGATTACCAAGAAAATGATGTTTATTATGTGGTTCAGCGGTCTAAGGGGTGCGATATCTTACGCTTTATCTCTGCATCTTGGATTTTCGGATGAAACCAGACATGTGATTATAACAACGACACTCATAATCGTGTTGTTTACTACTTTGTTCTTCGGAGGGTCCACTATGCCACTATTGAAATTTTTACGGGCAAACAAGAAAACAAAACGTGCACGACCTTTGCGCAAACAAAAGGAAGTAAGTTTGTCTAAAACAAAAGAGTGGGGGCAAGCAATCGATTCTGAACATTTATCTGAAATCACTGAAGAGGAACTTGAGGTGAATTATTCACACGCAACTCGTTTACGGGGCTTCGTACGATTTGATATGAAATATCTGACCCCGTTTTTTACGCGACGGTTTACTCATCAGGAGCTAAAAGATTGCAAAAGCCAAATGACAGACCTGACAAATCAATGGTATCAAGCGATTAGGATATCCAATGATAGAGAAACGGATGAAGAAGAAATTTTACAGCAGAATTCCCTTCCGAGCTCACGCAATAGTCTGCAAAGAGGTGTTTAG

Protein

MNVNQTVDSTTPSSTEKSNIVYEIGPSNSSILAVVQVNASAATPNASVNPSDAAPLPEKSSAEDEHNSSMAIFFVLCILALGILLIHLMLQTGFSYLPESVVIVFLGALIGMIINLMSIKNIANWRKEEAFSPTAFFLVLLPPIIFESGYNLHKGNFFQNIGSILLFAIVGTAISAFVIGAGIYLLGLAQVVYKLSFVESFAFGSLISAVDPVATVAIFHALDVDPVLNMLVFGESILNDAVAIVLTTAVLDSNDPFMSTGEAILSAINRFWLMFFASAGIGVLFALVSALLLKHVDLRKNPSLEFGMMLVFTYAPYVLAEGIHLSGIMAILFCGIVMSHYTHFNLSTITQVTMQQTMRTLAFIAETCVFAYLGLALFSFRHRVEPALVVWSIVMCLLGRAANIFPLALLCNKFREHKITKKMMFIMWFSGLRGAISYALSLHLGFSDETRHVIITTTLIIVLFTTLFFGGSTMPLLKFLRANKKTKRARPLRKQKEVSLSKTKEWGQAIDSEHLSEITEEELEVNYSHATRLRGFVRFDMKYLTPFFTRRFTHQELKDCKSQMTDLTNQWYQAIRISNDRETDEEEILQQNSLPSSRNSLQRGV

Similarity

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Belongs to the DPH1/DPH2 family.

Feature

chain  Sodium/hydrogen exchanger

Uniprot

A0A194PX96   A0A2Z4GWW3   A0A2A4JBD8   A9QVL3   A0A2H1VX86   A0A3S2NFH9   + More
A0A194QUD1   A0A212FDD6   A0A151WNV1   A0A2J7QB86   A0A2J7QB85   A0A0T6B3G6   E2B5T7   A0A0C9QG15   E2A1X6   A0A0C9RJM7   A0A151IIS8   E9IGJ8   A0A0J7KY84   A0A026W8M9   A0A3L8DRK0   A0A224XCE4   A0A2A3EIR0   A0A195BDL0   A0A151JYA3   A0A023F4U9   A0A195DPC5   A0A158NFI9   A0A2P8XM38   A0A146KTU6   A0A232FLC6   K7IQS2   A0A1B6L8B6   A0A1B6GTN8   A0A1W4WR07   A0A1B6CIL1   A0A2S2NUE7   A0A2H8TYV5   J9JJV7   A0A2S2R391   A0A1Y1LJ00   A0A310SEU4   A0A087ZZD1   A0A0L7L120   A0A0L7R952   F4X190   A0A0P4VFZ1   E0VLV5   U4UA95   N6TPG0   A0A067R5K9   A0A1S4F7V9   Q4L225   A0A182GWA7   A0A1L8DUX0   A0A1L8DUW5   A0A023EUT3   B0W243   A0A1L8DUW2   B0X6D4   A0A1Q3FER8   A0A1Q3FBV6   A0A1Q3FEV4   A0A1Q3FBQ6   V9IC16   T1PKQ7   A0A1I8PAH8   Q7QKG3   A0A0L0BLR8   V5GSC0   A0A182PJ05   A0A182HG44   A0A182V7N2   T1E186   A0A182XIP3   A0A1S4H161   A0A2M4BFS5   W5J8T6   A0A182TDT8   A0A2M3Z2U6   A0A2M3ZE89   A0A2M4A788   A0A182F5A4   A0A182K1L7   A0A182M4P3   A0A182JBD2   A0A182VUT8   A0A1A9W0H6   A0A182RGA3   A0A1A9V8X5   W8BLB4   A0A0K8TYZ1   A0A182QT37   A0A084VPS0   A0A1B0G0I4   A0A182YFZ2   A0A1A9ZJ05   A0A182NEK6   A0A034VCN8   A0A1B6ICY6  

Pubmed

26354079    29908900    22118469    20798317    21282665    24508170    + More
30249741    25474469    21347285    29403074    26823975    28648823    20075255    28004739    26227816    21719571    27129103    20566863    23537049    24845553    17510324    19193723    26483478    24945155    25315136    12364791    26108605    20920257    23761445    24495485    24438588    25244985    25348373   

EMBL

KQ459590    KPI97384.1    MH048893    AWW06965.1    NWSH01002234    PCG68864.1    + More
EU272023    ABX71221.2    ODYU01005003    SOQ45449.1    RSAL01000137    RVE46194.1    KQ461190    KPJ07161.1    AGBW02009074    OWR51751.1    KQ982893    KYQ49582.1    NEVH01016301    PNF25845.1    PNF25844.1    LJIG01016014    KRT81874.1    GL445887    EFN88906.1    GBYB01013468    JAG83235.1    GL435845    EFN72570.1    GBYB01013467    JAG83234.1    KQ977464    KYN02550.1    GL763048    EFZ20298.1    LBMM01001942    KMQ95502.1    KK107361    EZA51996.1    QOIP01000005    RLU23064.1    GFTR01007782    JAW08644.1    KZ288230    PBC31578.1    KQ976514    KYM82292.1    KQ981494    KYN40946.1    GBBI01002216    JAC16496.1    KQ980662    KYN14696.1    ADTU01014526    PYGN01001739    PSN33069.1    GDHC01018718    JAP99910.1    NNAY01000082    OXU31147.1    GEBQ01020028    JAT19949.1    GECZ01003992    JAS65777.1    GEDC01024010    JAS13288.1    GGMR01008043    MBY20662.1    GFXV01006533    MBW18338.1    ABLF02039927    GGMS01015191    MBY84394.1    GEZM01054490    JAV73613.1    KQ767065    OAD53516.1    JTDY01003664    KOB69193.1    KQ414627    KOC67400.1    GL888528    EGI59762.1    GDKW01003583    JAI53012.1    DS235281    EEB14361.1    KB632195    ERL89967.1    APGK01026647    KB740635    ENN79908.1    KK852729    KDR17572.1    AY326255    EU760347    CH477306    AAQ91612.1    ACJ02512.1    EAT44116.1    JXUM01092896    JXUM01092897    JXUM01092898    JXUM01092899    KQ564018    KXJ72926.1    GFDF01003861    JAV10223.1    GFDF01003862    JAV10222.1    GAPW01000403    JAC13195.1    DS231825    EDS28171.1    GFDF01003863    JAV10221.1    DS232411    EDS41284.1    GFDL01009001    JAV26044.1    GFDL01010008    JAV25037.1    GFDL01008993    JAV26052.1    GFDL01010034    JAV25011.1    JR039365    AEY58658.1    KA648523    AFP63152.1    AAAB01008797    EAA03626.4    JRES01001684    KNC20972.1    GALX01003974    JAB64492.1    APCN01004115    GAKT01000109    JAA92953.1    GGFJ01002765    MBW51906.1    ADMH02002093    ETN59290.1    GGFM01002093    MBW22844.1    GGFM01006072    MBW26823.1    GGFK01003290    MBW36611.1    AXCM01000484    AXCP01008030    GAMC01006988    JAB99567.1    GDHF01032813    JAI19501.1    AXCN02000851    ATLV01015034    KE524999    KFB39964.1    CCAG010017281    GAKP01019070    GAKP01019068    GAKP01019066    JAC39882.1    GECU01022921    JAS84785.1   

Proteomes

UP000053268    UP000218220    UP000283053    UP000053240    UP000007151    UP000075809    + More
UP000235965    UP000008237    UP000000311    UP000078542    UP000036403    UP000053097    UP000279307    UP000242457    UP000078540    UP000078541    UP000078492    UP000005205    UP000245037    UP000215335    UP000002358    UP000192223    UP000007819    UP000005203    UP000037510    UP000053825    UP000007755    UP000009046    UP000030742    UP000019118    UP000027135    UP000008820    UP000069940    UP000249989    UP000002320    UP000095301    UP000095300    UP000007062    UP000037069    UP000075885    UP000075840    UP000075903    UP000076407    UP000000673    UP000075902    UP000069272    UP000075881    UP000075883    UP000075880    UP000075920    UP000091820    UP000075900    UP000078200    UP000075886    UP000030765    UP000092444    UP000076408    UP000092445    UP000075884   

Pfam

PF00999   Na_H_Exchanger        + More
PF01866   Diphthamide_syn
PF06699   PIG-F

Interpro

IPR018422   Cation/H_exchanger_CPA1        + More
IPR006153   Cation/H_exchanger       
IPR004709   NaH_exchanger       
IPR042265   DPH1/DPH2_3       
IPR016435   DPH1/DPH2       
IPR009580   GPI_biosynthesis_protein_Pig-F       

Gene 3D

3.40.50.11860    

ProteinModelPortal

A0A194PX96   A0A2Z4GWW3   A0A2A4JBD8   A9QVL3   A0A2H1VX86   A0A3S2NFH9   + More
A0A194QUD1   A0A212FDD6   A0A151WNV1   A0A2J7QB86   A0A2J7QB85   A0A0T6B3G6   E2B5T7   A0A0C9QG15   E2A1X6   A0A0C9RJM7   A0A151IIS8   E9IGJ8   A0A0J7KY84   A0A026W8M9   A0A3L8DRK0   A0A224XCE4   A0A2A3EIR0   A0A195BDL0   A0A151JYA3   A0A023F4U9   A0A195DPC5   A0A158NFI9   A0A2P8XM38   A0A146KTU6   A0A232FLC6   K7IQS2   A0A1B6L8B6   A0A1B6GTN8   A0A1W4WR07   A0A1B6CIL1   A0A2S2NUE7   A0A2H8TYV5   J9JJV7   A0A2S2R391   A0A1Y1LJ00   A0A310SEU4   A0A087ZZD1   A0A0L7L120   A0A0L7R952   F4X190   A0A0P4VFZ1   E0VLV5   U4UA95   N6TPG0   A0A067R5K9   A0A1S4F7V9   Q4L225   A0A182GWA7   A0A1L8DUX0   A0A1L8DUW5   A0A023EUT3   B0W243   A0A1L8DUW2   B0X6D4   A0A1Q3FER8   A0A1Q3FBV6   A0A1Q3FEV4   A0A1Q3FBQ6   V9IC16   T1PKQ7   A0A1I8PAH8   Q7QKG3   A0A0L0BLR8   V5GSC0   A0A182PJ05   A0A182HG44   A0A182V7N2   T1E186   A0A182XIP3   A0A1S4H161   A0A2M4BFS5   W5J8T6   A0A182TDT8   A0A2M3Z2U6   A0A2M3ZE89   A0A2M4A788   A0A182F5A4   A0A182K1L7   A0A182M4P3   A0A182JBD2   A0A182VUT8   A0A1A9W0H6   A0A182RGA3   A0A1A9V8X5   W8BLB4   A0A0K8TYZ1   A0A182QT37   A0A084VPS0   A0A1B0G0I4   A0A182YFZ2   A0A1A9ZJ05   A0A182NEK6   A0A034VCN8   A0A1B6ICY6  

PDB

4CZ9     E-value=2.51596e-11,     Score=168

KEGG

101737790    K14724 solute carrier family 9 (sodium/hydrogen exchanger), member 8 | (RefSeq) sodium/hydrogen exch

GO

GO:0015385   GO:0006885   GO:0016021   GO:0006814   GO:0015297   GO:0017183   GO:0005789   GO:0006506   GO:0005794   GO:0015386   GO:0051453   GO:0071805   GO:0006812   GO:0015299   GO:0006811   GO:0016020   GO:0005634   GO:0006260   GO:0055085  

PANTHER

PTHR10110  

Length:

605

Number of predicted TMHs:

12

Exp number of AAs in TMHs:

261.11126

Exp number, first 60 AAs:

0.1382

Total prob of N-in:

0.93958

inside

1  -  67

TMhelix

68  -  90

outside

91  -  99

TMhelix

100  -  119

inside

120  -  130

TMhelix

131  -  150

outside

151  -  164

TMhelix

165  -  187

inside

188  -  199

TMhelix

200  -  222

outside

223  -  231

TMhelix

232  -  251

inside

252  -  270

TMhelix

271  -  293

outside

294  -  316

TMhelix

317  -  339

inside

340  -  359

TMhelix

360  -  379

outside

380  -  388

TMhelix

389  -  411

inside

412  -  423

TMhelix

424  -  443

outside

444  -  457

TMhelix

458  -  480

inside

481  -  605

 

 

Pi

208.043546

Theta

20.551157

Tajima's D

-1.412659

CLR

201.284344

CSRT

0.0689465526723664

Interpretation

Uncertain