Gene

KWMTBOMO06624

Pre Gene Modal

BGIBMGA011691

Annotation

PREDICTED:_glutamate_receptor_ionotropic?_NMDA_2B-like_[Bombyx_mori]

Location

Bomo_Chr11(+):11821703-11833917      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 3.813

CDS

ATGCAGACGCATGCAGCTCTAATGGCGCTGGCTGCGCTGGGAGCGCTAGCGGCGGCGGCGGCGGCGGAGCGCGGCAGTGGCATCAAAGTCGGCAGCGGTGGTGGAATGGCCAGTAGTCGAGATGGTGGCCGTGGAAGTGGTGTACGCATCGGAGACGGAATCAGGCGTCCACGAACTTCACCTGCGCCTCCTCCTCCTCGAGCTCCTTCTTCCATCACCGCTGCTCTCGTCGTGCCACATAAGGCCTTTGGCACACGAGATTACACCAAGGCCGAAAAAGCTGCTCTATCAAAATTACCGCGAAAACTGAAACTTTTTTCTCAAGTGCGCCTGAACATAACGCTCTCTACGCAAGGCTTGACGCCTAGTCCTATGTCTATCCTGGACTCGCTATGTAAAGAATTTCTAGCAGTCAACGTGTCTGCTATCCTTTATCTTATGAATCACGAACAATACGGGCGCTCTACTGCCTCTGCACAATATTTTCTACAACTCGCAGGGTATCTCGGCATACCGGTAATTGCATGGAATGCAGACAACAGCGGGCTTGAGAAGCGCGCGTCACATGCTTCTTTACGTCTTCAATTGGCCCCATCCATTGAACATCAAACAGCCGCGATGCTTTCTATTTTAGAAAGATACAAATGGCATCAGTTCAGCGTCGTCACCTCAGCTATTGCCGGACATGACGATTTCATACAGGCTGTACGTGAAAGAGTGACGGCACTACAAGATCGATTTAAATTCACGATACTTAACGCAATAGTCGTTAAGAGGTCATCAGATCTAAATGAATTGGTCACAAGTGAAGCGCGTGTGATGTTACTGTATGCGACCAGAGAAGAGGCAGCGGAAATACTATCTGCCGCTGGAGACTTACACCTTACCGGCGAAAGTTTTGTGTGGATCGTTACACAAAGTGTATTAGGATCTATGCAACAACCCAACAAATTTCCCGTCGGCATGCTTGGTGTACATTTCGACACGTCGAGTTCTTCTTTGATATCAGAAATAGCAACCGCTGTTAAAGTATTTGCCTACGGCGTGGAGTCGTACATATCCGAGCCTGAGAATGTGCGTTACCCACTGGGCACTAGACTATCGTGCAGTGGCGCGGGAGCAGGCGAAGCACGTTGGTCTACAGGCGAGCGATTCTATAGGCATTTGCGGAATGTCAGCGTTGAAGGAGAAGTAGGGAGACCGAGCATCGAATTCACCCCTGATGGTGAATTACGAGCTGCTGAACTTAAAATTATGAATCTAAGACCTGCCATAGGCGAACAGTTGGTATGGGAAGAAATCGGAACTTGGAACTCTTATCCGAAAGAACGACTCGTCATCAAAGACATTGTTTGGCCTGGCGGTCTACATACTCCACCACAAGGCGTGCCAGAAAAGTTCCACATGCGCATAACCTTCCTAGAAGAACCACCGTATATTAACTTAGCGCCACCGGATCCCGTTAGTGGACGTTGCTCTTTAGACAGAGGTGTGATATGCCGTGTCGCACCGGAAACAGAAGTTGCTGGTCTCGAAGCCGGTACTGCTCACGGAAATAGCTCTCTATACCAGTGTTGCAGTGGATTCTGTATAGATCTGCTGCAACAACTTGCTGAACATCTCGGATTTACCTATGAATTGGTCCGCGTCGAGGATGGACGTTGGGGCACATTGCACTACGGCAAGTGGAACGGTTTGATTGCCGATCTTGTCAACAAGAAAACCGATATGGTTTTAACGTCCTTAATAATAAATTCGGACCGGGAAGCAGTAGTAGATTTCAGTGTGCCATTTATGGAGACCGGTGTTGCAATTGTGGTGGCCAAACGAACAGGCATAATTTCCCCAACGGCTTTCTTAGAACCTTTCGACACTGCTTCGTGGATGCTCGTGGGCGCTGTAGCTATACAAGCTGCTACTTTTTCAATATTCTTCTTCGAATGGATGTCACCGAGTGGATTCGACTGCTCAACTGGCAACTCAAAACGTGTTCCACAAAATCGATTTTCGCTATGTCGCACGTATTGGATTGTTTGGGCAGTTTTATTTCAAGCGTCAGTACACGTTGATTCACCTAGAGGTTTCACAGCTCGTTTCATGACCAACATGTGGGCGATGTTCGCCGTCGTGTTTCTGGCTATATACACAGCTAATTTGGCTGCGTTTATGATAACTCGCGAGGAATACCACGAATTAAGCGGCTTAGACGATCCCAGGATCGCGAGACCACTCTCACAGCGTCCGCCATTAAAATTCGGCACAGTACCGTGGTCACACACAGATGCTACGCTCGCTAAATACTTCCCGGAACCACACGCTTATATGGCTCGGTACAATCGGAGTACAGTTAGCGCAGGAGTGACGAGCGTACTTACGGGAGATCTTGACGCATTCATTTATGACGGTACTGTATTGGATTATCTGGTATCACAAGACGAAGATTGTAGACTGTTGACGGTAGGGGCTTGGTACGCCATGTCCGGGTACGGCCTCGCGTTTACGCGGAACTCGAAATATCTCAGTATGTTCAATAAACGGTTACTAGATTTACGAGCCAATGGTGATCTTGAAAGACTACGAAGGTACTGGATGACTGGAACGTGTAAGCCCAATAAACAAGAGCATAAGTCTTCAGATCCTCTGGCCTTGGAGCAATTCTTATCAGCATTCCTGCTACTTATGGCAGGAATTCTGCTGGCAGCATTGTTGCTCCTGTTAGAACATGTCTATTTTAAATACATGCGCACTCATTTGGCGGCCTCAAAGGCTGGATCGTGTTGTGCGCTAGTTTCGTTATCAATGGGTCAGTCTCTGACTTTTCACGGCGCCGTAGTCGAAGCGGCTGCTCGAGGATTAGGCACAGGCGAACGTGGACACTGTCGCTCCGCCATATGCGCTGCTCAATTATGGCGCGCACGACACGAACGTGATGTAGCCATGGCCAGGGTGAGGCAGCTGGCTGCGGCGTTAGCGGCACACGGGCTGGCGCCGCCGCCACGCCGACTCGCTTCGGCGGCGGCGCTGCTGGCGGGTGGCATGCCGCACGACGCCACGCGGCCGCGCATGCTGCGCCCGCCCGCCGACCTACTGCCGGACCTCGATCGCCCTCTCTCGTGTGGTGATTTGCGATCGAGAGGGCGGACACGAGTAGAAATGGAAACAGTGCTGTGA

Protein

MQTHAALMALAALGALAAAAAAERGSGIKVGSGGGMASSRDGGRGSGVRIGDGIRRPRTSPAPPPPRAPSSITAALVVPHKAFGTRDYTKAEKAALSKLPRKLKLFSQVRLNITLSTQGLTPSPMSILDSLCKEFLAVNVSAILYLMNHEQYGRSTASAQYFLQLAGYLGIPVIAWNADNSGLEKRASHASLRLQLAPSIEHQTAAMLSILERYKWHQFSVVTSAIAGHDDFIQAVRERVTALQDRFKFTILNAIVVKRSSDLNELVTSEARVMLLYATREEAAEILSAAGDLHLTGESFVWIVTQSVLGSMQQPNKFPVGMLGVHFDTSSSSLISEIATAVKVFAYGVESYISEPENVRYPLGTRLSCSGAGAGEARWSTGERFYRHLRNVSVEGEVGRPSIEFTPDGELRAAELKIMNLRPAIGEQLVWEEIGTWNSYPKERLVIKDIVWPGGLHTPPQGVPEKFHMRITFLEEPPYINLAPPDPVSGRCSLDRGVICRVAPETEVAGLEAGTAHGNSSLYQCCSGFCIDLLQQLAEHLGFTYELVRVEDGRWGTLHYGKWNGLIADLVNKKTDMVLTSLIINSDREAVVDFSVPFMETGVAIVVAKRTGIISPTAFLEPFDTASWMLVGAVAIQAATFSIFFFEWMSPSGFDCSTGNSKRVPQNRFSLCRTYWIVWAVLFQASVHVDSPRGFTARFMTNMWAMFAVVFLAIYTANLAAFMITREEYHELSGLDDPRIARPLSQRPPLKFGTVPWSHTDATLAKYFPEPHAYMARYNRSTVSAGVTSVLTGDLDAFIYDGTVLDYLVSQDEDCRLLTVGAWYAMSGYGLAFTRNSKYLSMFNKRLLDLRANGDLERLRRYWMTGTCKPNKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYMRTHLAASKAGSCCALVSLSMGQSLTFHGAVVEAAARGLGTGERGHCRSAICAAQLWRARHERDVAMARVRQLAAALAAHGLAPPPRRLASAAALLAGGMPHDATRPRMLRPPADLLPDLDRPLSCGDLRSRGRTRVEMETVL

Similarity

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.

Uniprot

A0A2H1VNY7   A0A075TD99   H9JQ85   A0A345BF20   A0A212F5V2   A0A194PX73   + More
A0A0L7LRJ9   A0A2A4JKX7   A0A0F7QHN7   A0A0B5A3G8   A0A0K8TUD8   A0A194QQE4   A0A0V0J153   A0A223HCZ7   A0A139WKM8   A0A0C9RWB2   A0A139WKV8   A0A3L8E2E5   A0A195FTC7   A0A195DKJ2   A0A0L7R9Q3   A0A2A3ENQ0   A0A088A9N9   A0A026WHI8   A0A0L0C858   A0A0M3SBL9   A0A336MC74   A0A1I8M7N9   A0A1I8PVH3   A0A075Q6F7   A0A075Q6G4   A0A075Q6G2   A0A075Q362   A0A0R3P3I3   A0A0M4F7S4   A0A195BG93   A0A0P8XKB0   Q29J15   A0A1S4FIQ8   A0A0Q9XF30   A0A075Q359   B3MRX1   Q16ZR9   B4L761   A0A075QB19   A0A0R3NYN4   B4GTK0   B4PY38   A0A182MIQ3   A0A075Q109   X2JDW0   A0A075Q438   B3P9J4   A0A3B0K250   A0A075Q116   Q9W581   A0A3B0JXG0   A0A182W628   B4I9F7   B4JXG9   A0A3B0JXF2   Q6IWN7   Q16IF5   A0A182RVV6   A0A075Q434   A0A084VQH0   A0A182IWF8   A0A182FMM9   W8C4A0   A0A1J1IN94   K7J2X0   A0A2H8TMD0   A0A1S4G051   A0A1W4VT10   A0A1W4VSC6   A0A1A9X1D8   A0A1B0GFF3   W5JDA1   B0X6V2   A0A151WWC7   E1JJC6   Q7PHP7   A0A1A9YQ94   J9K6V7   B4MB33   A0A195D7B3   B4NPT1   A0A1B0A0B1   Q8MM14   A0A1B0BZ01   A0A2S2QKY9   O76903   B4R2Z6   A0A0C9QFF6   Q8MX77   A0A182GEK7   A0A1L2YXQ5   A0A1L2YXN9  

Pubmed

25027790    19121390    29727827    22118469    26354079    26227816    + More
25803580    26017144    27006164    28150741    18362917    19820115    30249741    24508170    26108605    26265180    25315136    25657209    15632085    17994087    23185243    17510324    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    15823532    26109357    26109356    24438588    24495485    20075255    20920257    23761445    9087549    12364791    14747013    17210077    26483478   

EMBL

ODYU01003588    SOQ42545.1    KF768737    AIG51931.1    BABH01012012    MG820673    + More
AXF48844.1    AGBW02010125    OWR49121.1    KQ459590    KPI97364.1    JTDY01000244    KOB78085.1    NWSH01001177    PCG72244.1    LC017780    BAR64794.1    KJ542735    AJD81619.1    GCVX01000126    JAI18104.1    KQ461190    KPJ07180.1    GDKB01000028    JAP38468.1    KY283581    AST36241.1    KQ971326    KYB28456.1    GBYB01013240    JAG83007.1    KYB28457.1    QOIP01000001    RLU26874.1    KQ981272    KYN43865.1    KQ980765    KYN13357.1    KQ414627    KOC67486.1    KZ288212    PBC32826.1    KK107242    EZA54544.1    JRES01000755    KNC28623.1    KP843222    ALD51358.1    UFQS01002934    UFQT01000673    UFQT01002934    SSX14928.1    SSX26393.1    KJ747199    KJ747200    KJ747202    AIG13069.1    AIG13070.1    AIG13072.1    KJ747210    AIG13080.1    KJ747205    AIG13075.1    KJ747206    AIG13076.1    CH379063    KRT06085.1    CP012528    ALC48300.1    KQ976488    KYM83635.1    CH902622    KPU75185.1    EAL32487.3    KRT06083.1    CH933812    KRG07184.1    KJ747201    AIG13071.1    EDV34526.1    CH477485    EAT40152.1    EDW06207.2    KJ747207    AIG13077.1    KRT06084.1    CH479190    EDW25870.1    CM000162    EDX00911.1    AXCM01010787    AXCM01010788    KJ747204    AIG13074.1    AE014298    AHN59259.1    KJ747208    AIG13078.1    CH954183    EDV45490.1    OUUW01000011    SPP86742.1    KJ747209    AIG13079.1    AY616148    AAF45640.2    AAT40461.1    SPP86744.1    CH480825    EDW43838.1    CH916376    EDV95445.1    SPP86745.1    AY616149    AAT40462.1    ACZ95174.1    CH478081    EAT34043.1    KJ747203    AIG13073.1    ATLV01015210    ATLV01015211    ATLV01015212    ATLV01015213    KE525003    KFB40214.1    GAMC01005659    JAC00897.1    CVRI01000056    CRL01703.1    GFXV01003335    MBW15140.1    CCAG010005258    ADMH02001564    ETN62051.1    DS232425    EDS41623.1    KQ982691    KYQ52204.1    ACZ95173.1    AAAB01008924    EAA44457.4    ABLF02029749    ABLF02029750    ABLF02029753    ABLF02029756    ABLF02029758    CH940655    EDW66442.2    KQ976749    KYN08766.1    CH964291    EDW86521.2    AY050490    AY050491    AY616144    AY616145    AY616146    AY616147    AAF45639.3    AAL12478.1    AAL12479.1    AAN09051.2    AAT40457.1    AAT40458.1    AAT40459.1    AAT40460.1    ACZ95172.1    JXJN01022924    JXJN01022925    GGMS01009222    MBY78425.1    AL031027    CAA19838.1    CM000366    EDX16850.1    GBYB01013238    JAG83005.1    AF381249    AAM46167.1    JXUM01058181    JXUM01058182    KQ561991    KXJ76968.1    KX016789    APF30038.1    KX016785    APF30034.1   

Proteomes

UP000005204    UP000007151    UP000053268    UP000037510    UP000218220    UP000053240    + More
UP000007266    UP000279307    UP000078541    UP000078492    UP000053825    UP000242457    UP000005203    UP000053097    UP000037069    UP000095301    UP000095300    UP000001819    UP000092553    UP000078540    UP000007801    UP000009192    UP000008820    UP000008744    UP000002282    UP000075883    UP000000803    UP000008711    UP000268350    UP000075920    UP000001292    UP000001070    UP000075900    UP000030765    UP000075880    UP000069272    UP000183832    UP000002358    UP000192221    UP000091820    UP000092444    UP000000673    UP000002320    UP000075809    UP000007062    UP000092443    UP000007819    UP000008792    UP000078542    UP000007798    UP000092445    UP000092460    UP000000304    UP000069940    UP000249989   

PRIDE

H9JQ85    X2JDW0    Q9W581    Q6IWN7    E1JJC6    Q8MM14    + More
O76903    Q8MX77   

Pfam

PF01094   ANF_receptor        + More
PF00060   Lig_chan
PF10613   Lig_chan-Glu_bd
PF00497   SBP_bac_3

Interpro

IPR001828   ANF_lig-bd_rcpt        + More
IPR001508   Iono_rcpt_met       
IPR019594   Glu/Gly-bd       
IPR001320   Iontro_rcpt       
IPR028082   Peripla_BP_I       
IPR001638   Solute-binding_3/MltF_N       

SUPFAM

SSF53822   SSF53822       

ProteinModelPortal

A0A2H1VNY7   A0A075TD99   H9JQ85   A0A345BF20   A0A212F5V2   A0A194PX73   + More
A0A0L7LRJ9   A0A2A4JKX7   A0A0F7QHN7   A0A0B5A3G8   A0A0K8TUD8   A0A194QQE4   A0A0V0J153   A0A223HCZ7   A0A139WKM8   A0A0C9RWB2   A0A139WKV8   A0A3L8E2E5   A0A195FTC7   A0A195DKJ2   A0A0L7R9Q3   A0A2A3ENQ0   A0A088A9N9   A0A026WHI8   A0A0L0C858   A0A0M3SBL9   A0A336MC74   A0A1I8M7N9   A0A1I8PVH3   A0A075Q6F7   A0A075Q6G4   A0A075Q6G2   A0A075Q362   A0A0R3P3I3   A0A0M4F7S4   A0A195BG93   A0A0P8XKB0   Q29J15   A0A1S4FIQ8   A0A0Q9XF30   A0A075Q359   B3MRX1   Q16ZR9   B4L761   A0A075QB19   A0A0R3NYN4   B4GTK0   B4PY38   A0A182MIQ3   A0A075Q109   X2JDW0   A0A075Q438   B3P9J4   A0A3B0K250   A0A075Q116   Q9W581   A0A3B0JXG0   A0A182W628   B4I9F7   B4JXG9   A0A3B0JXF2   Q6IWN7   Q16IF5   A0A182RVV6   A0A075Q434   A0A084VQH0   A0A182IWF8   A0A182FMM9   W8C4A0   A0A1J1IN94   K7J2X0   A0A2H8TMD0   A0A1S4G051   A0A1W4VT10   A0A1W4VSC6   A0A1A9X1D8   A0A1B0GFF3   W5JDA1   B0X6V2   A0A151WWC7   E1JJC6   Q7PHP7   A0A1A9YQ94   J9K6V7   B4MB33   A0A195D7B3   B4NPT1   A0A1B0A0B1   Q8MM14   A0A1B0BZ01   A0A2S2QKY9   O76903   B4R2Z6   A0A0C9QFF6   Q8MX77   A0A182GEK7   A0A1L2YXQ5   A0A1L2YXN9  

PDB

5FXK     E-value=4.8653e-126,     Score=1159

KEGG

101735975    K05210 glutamate receptor ionotropic, NMDA 2B | (RefSeq) glutamate receptor ionotropic, NMDA 2B-like

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0004970   GO:0045211   GO:0030054   GO:0005886   GO:0006811   GO:0008328   GO:0072375   GO:0007616   GO:0050975   GO:0004972   GO:0035235   GO:0004872   GO:0005216   GO:0016020   GO:0005234   GO:0005634   GO:0006260   GO:0038023  

Subcellular location

  

SignalP

Position:   1 - 21,         Likelihood:  0.885746

 

 

Length:

1056

Number of predicted TMHs:

5

Exp number of AAs in TMHs:

111.97612

Exp number, first 60 AAs:

4.94768

Total prob of N-in:

0.25707

outside

1  -  625

TMhelix

626  -  648

inside

649  -  668

TMhelix

669  -  688

outside

689  -  702

TMhelix

703  -  722

inside

723  -  816

TMhelix

817  -  834

outside

835  -  888

TMhelix

889  -  911

inside

912  -  1056

 

 

Pi

169.166465

Theta

161.933405

Tajima's D

0.141218

CLR

0.634602

CSRT

0.406629668516574

Interpretation

Uncertain