Gene

KWMTBOMO06616

Pre Gene Modal

BGIBMGA011789

Annotation

PREDICTED:_dipeptidase_1-like_[Papilio_polytes]

Location

Bomo_Chr11(-):11707560-11720742      View in EpiBrowser

Full name

Dipeptidase      

Location in the cell

Mitochondrial   Reliability : 1.314

CDS

ATGTTAGCGCGCCGAGCCGCGGCCACCACGCGGCGGGCGGCCTCTCGCCTCATCGCGCTCATGGAGCCACCGTGGGAGCTGGAACTCGAACTGCGACGGCACATCGAAAATTGCGCTTGTACCTGCGACCACATGGGCTACGGGAACTATATGGACTACCAGATTGCGCCTGCGGCGCACGCCTGTCTGTGCCGTGCAATTACTTCGCCGCACGCCCACGCTGCTGTTCCCGAAGGCATGACCTTTCCTGGACCACTGCCCGATGTAGCAGAGAGATGTGGTCGTTGGGCTCCAGATTCACTGTCAGCTTCAGCGTCAGGTAGTTCGGATGAGAAACCCACACCTCGTCGTCCACGTTGGAGAATAGCTTTGGCCGCACTAGTTGTGTTAGCTGGTTTGTGTGCTGCACTAGCATTGCCACTCGCTTTAGGAGGTGGCGGTCGTGCTACACCAGAACAACGGCTCACGACCATACGTCGCATGTTACGAGATTCTCCGCTTGTCGACGGTCATAATGATTTGGCGTGGAACGTTCGAAAGTTTTTACATAATAAAATTGGTGACTTCAATTTGAGCGCTGGTCTGGAAGGATTAGAGCCGTGGGCACGTTCGCGCTGGTCGCATACTGATATACCACGATTAAGACTTGGTCAGGTCGGTGCTCAATTTTGGTCGGCATACGTCCCGTGCGGTGCGCGGGACAGAGATGCTGTGCAGTTAGCTTTAGAACAAATGGATGTTATTAAACGAATAGTTGAGATGAATGCAGCACATTTAGCACTCGTCACGGACGCGGCTGAATTATTAGAAGCGCATCGAGAAGGTCGGATAGCGTCATTAATTGGTGTAGAAGGCGGTCATGCTCTTGGAGATTCCCTTGCAGTTTTACGTGCATTTTATCAACTTGGCGCTCGTTATCTAACAGTAACACACACGTGTGACACAAAATGGGCACGAGCAGCTGGTAGCTCTGGTGGTCTTACAGAGTTTGGACGAGCAGTCGTTCGAGAAATGAATAGATTGGGTATGGTTGTCGACTTGTCTCACGCCGGTGAAGAGACAGCGCGTGATGCGTTAGAAATGTCGCAAGCACCGGTGGTGTTTTCTCATTCGGGAGCAGCCGCGTTATGTAATTCATCTAGAAACGTGCCCGATGATTTGTTACGTATGATCGCAGCGAACGGGGGAGTTGTCATGATTAACTTCTATGCAAAACTAGTGACGTGCGGAGAGCGTGCAACTGTTGAAGATGTTGTGGCACATATTAACCATGTTAGACGCGTTGCTGGCGTTGAACACGTAGGCTTGGGGGCGGGCTACGACGGTATTGATGCTCCACCTGAAGGATTAGAAGATGTTTCTCGATATCCCCACTTGCTAGCAGAACTATTACGAGATCCCGATTGGAGTGAAGAAGATGTCCGCAAATTGGCCGGTATGAATGTTGTACGTGTGTTACAAAATGTGGAGCGCGTACGAGATCAGTGGCGGCGTGCTGCAGTTCTTCCTGGAGAAGAATCAGCAGGTGTGCGTCGTGGAGACTGCGTTTACGGACCCGCGTGA

Protein

MLARRAAATTRRAASRLIALMEPPWELELELRRHIENCACTCDHMGYGNYMDYQIAPAAHACLCRAITSPHAHAAVPEGMTFPGPLPDVAERCGRWAPDSLSASASGSSDEKPTPRRPRWRIALAALVVLAGLCAALALPLALGGGGRATPEQRLTTIRRMLRDSPLVDGHNDLAWNVRKFLHNKIGDFNLSAGLEGLEPWARSRWSHTDIPRLRLGQVGAQFWSAYVPCGARDRDAVQLALEQMDVIKRIVEMNAAHLALVTDAAELLEAHREGRIASLIGVEGGHALGDSLAVLRAFYQLGARYLTVTHTCDTKWARAAGSSGGLTEFGRAVVREMNRLGMVVDLSHAGEETARDALEMSQAPVVFSHSGAAALCNSSRNVPDDLLRMIAANGGVVMINFYAKLVTCGERATVEDVVAHINHVRRVAGVEHVGLGAGYDGIDAPPEGLEDVSRYPHLLAELLRDPDWSEEDVRKLAGMNVVRVLQNVERVRDQWRRAAVLPGEESAGVRRGDCVYGPA

Catalytic Activity

Hydrolysis of dipeptides.

Cofactor

Zn(2+)

Subunit

Homodimer; disulfide-linked.

Similarity

Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.

Feature

chain  Dipeptidase

Uniprot

A0A2A4JTP4   A0A212FJH9   H9JQI3   A0A2H1X0W8   A0A194QUG1   A0A0L7LMB7   + More
A0A0L7QR01   E2BQQ6   A0A026WVD9   A0A195CYT1   A0A158NRM6   A0A154PLN3   A0A0C9QKJ5   A0A1Y1MF53   D6WFQ4   A0A195F589   A0A1W4XTC1   A0A195BVX9   E0VVY3   A0A0K8T262   N6SWP7   A0A2J7RAC8   A0A0P4W9D6   A0A182VM54   A0A182XAL8   Q7QCH9   A0A182HSF9   A0A182P3S6   A0A1B0FAT5   W8AEG4   A0A336M0A2   A0A0L0CF12   A0A1B0A6R5   W8B9T9   A0A0P5H620   A0A0P5N2F6   A0A0P5XDI9   A0A1I8M0Q7   E0VS36   A0A0N8AE64  

EC Number

3.4.13.19

Pubmed

22118469    19121390    26354079    26227816    20798317    24508170    + More
21347285    28004739    18362917    19820115    20566863    23537049    12364791    14747013    17210077    24495485    26108605    25315136   

EMBL

NWSH01000601    PCG75405.1    AGBW02008266    OWR53884.1    BABH01012020    ODYU01012538    + More
SOQ58912.1    KQ461190    KPJ07191.1    JTDY01000642    KOB76361.1    KQ414784    KOC61057.1    GL449798    EFN81975.1    KK107087    EZA59992.1    KQ977110    KYN05732.1    ADTU01002074    ADTU01002075    ADTU01002076    ADTU01002077    ADTU01002078    ADTU01002079    ADTU01002080    ADTU01002081    ADTU01002082    ADTU01002083    KQ434973    KZC12762.1    GBYB01015288    JAG85055.1    GEZM01033559    JAV84221.1    KQ971319    EEZ99578.1    KQ981805    KYN35561.1    KQ976403    KYM92121.1    DS235815    EEB17539.1    GBRD01006335    JAG59486.1    APGK01053603    APGK01053604    KB741231    KB631770    ENN72219.1    ERL86005.1    NEVH01006576    PNF37770.1    GDRN01070938    JAI63790.1    AAAB01008859    EAA08208.5    APCN01000271    CCAG010021067    GAMC01019979    GAMC01019978    GAMC01019975    GAMC01019971    JAB86580.1    UFQT01000071    SSX19398.1    JRES01000472    KNC30988.1    GAMC01019981    GAMC01019974    JAB86574.1    GDIQ01238485    JAK13240.1    GDIQ01155760    JAK95965.1    GDIP01074685    JAM29030.1    DS235742    EEB16192.1    GDIP01156225    JAJ67177.1   

Proteomes

UP000218220    UP000007151    UP000005204    UP000053240    UP000037510    UP000053825    + More
UP000008237    UP000053097    UP000078542    UP000005205    UP000076502    UP000007266    UP000078541    UP000192223    UP000078540    UP000009046    UP000019118    UP000030742    UP000235965    UP000075903    UP000076407    UP000007062    UP000075840    UP000075885    UP000092444    UP000037069    UP000092445    UP000095301   

PRIDE

H9JQI3   

Pfam

PF01244   Peptidase_M19

Interpro

IPR032466   Metal_Hydrolase        + More
IPR008257   Pept_M19       
IPR000180   Dipep_AS       

SUPFAM

SSF51556   SSF51556       

CDD

cd01301  rDP_like

ProteinModelPortal

A0A2A4JTP4   A0A212FJH9   H9JQI3   A0A2H1X0W8   A0A194QUG1   A0A0L7LMB7   + More
A0A0L7QR01   E2BQQ6   A0A026WVD9   A0A195CYT1   A0A158NRM6   A0A154PLN3   A0A0C9QKJ5   A0A1Y1MF53   D6WFQ4   A0A195F589   A0A1W4XTC1   A0A195BVX9   E0VVY3   A0A0K8T262   N6SWP7   A0A2J7RAC8   A0A0P4W9D6   A0A182VM54   A0A182XAL8   Q7QCH9   A0A182HSF9   A0A182P3S6   A0A1B0FAT5   W8AEG4   A0A336M0A2   A0A0L0CF12   A0A1B0A6R5   W8B9T9   A0A0P5H620   A0A0P5N2F6   A0A0P5XDI9   A0A1I8M0Q7   E0VS36   A0A0N8AE64  

PDB

1ITU     E-value=1.44663e-89,     Score=842

KEGG

101736374    K01273 membrane dipeptidase [EC:3.4.13.19] | (RefSeq) dipeptidase 1-like

GO

GO:0031225   GO:0046872   GO:0016805   GO:0016021   GO:0008237   GO:0008235   GO:0008239   GO:0006508   GO:0016787   GO:0004003   GO:0006289   GO:0006367   GO:0006811   GO:0016020   GO:0005634   GO:0006260  

PANTHER

PTHR10443  

Subcellular location

Membrane  

Length:

520

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.55082

Exp number, first 60 AAs:

0.00023

Total prob of N-in:

0.99784

inside

1  -  121

TMhelix

122  -  144

outside

145  -  520

 

 

Pi

225.518931

Theta

180.128363

Tajima's D

0.677628

CLR

0.251252

CSRT

0.569871506424679

Interpretation

Possibly Positive selection