Gene

KWMTBOMO06595  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011674

Annotation

puromycin-sensitive_aminopeptidase-like_[Bombyx_mori]

Location

Bomo_Chr11(+):11269442-11278230      View in EpiBrowser

Full name

Aminopeptidase      

Location in the cell

Cytoplasmic   Reliability : 2.356

CDS

ATGCCAGAGAACAAGCCGTTTCAACGACTTCCTAATAATGTGATTCCTAAGCATTATGCATTGGAATTGATTCCAAATCTGGAAAAATTTACTTTCAAGGGAAAAACTGCGGTGAAAGTATCGATTGTTAATCCAACGAATGTGATAGTATTGAATAGCTTAGACTTGGATTTGAAAAATGTGAAACTTCAGTATAACGATGGCTCTAATTCAGCGATAATTCCATCGTCAGTAGAATTGAGTACAACTGATGAAACAGCAAGTATTTATTTCTCAGAATCTTTACTAGAAGGCGAAGCGACGCTTTATTCTGAGTTTACAGGTGAAATAAATGACAAAATGAAAGGCTTGTACCGCAGTAAATACATTGCTCCCAATGGAGAAGAACGATATGCGGCTGTCACCCAATTTGAAGCGACAGATGCACGACGATGTTTCCCTTGCTGGGATGAACCTGCAATTAAAGCTACTTTTGATATAACCTTACAAGTTCCGGCTGATCGTGTTGCTTTGTCTAATATGCCTGTAAAACAAGAAAAGATTGCAGACAATACAAGGATCATACAATTTGACACAACACCAATAATGTCAACATATTTAGTGGCTGTTGTTGTTGGTGAATATGATTATGTGGAAAAGAAATCTAATGATGGAATTCTAGTAAGGGTTTATACTCCTGTAGGCAAAAGTAAACAGGGGTTGTTTGCACTTGAAGTGGCTGCACGAGTTTTGCCTTATTATAAAGATTACTTTGATATTGCATACCCCTTGCCCAAAATAGACCTGATTGCTATAGCAGACTTTTCAGCAGGAGCTATGGAGAATTGGGGATTAGTAACATATAGGGAGACCTGTCTCTTGGTAGATGAAGAACATACTTCTGCTGTTAGAAGACAATGGATAGCTTTAGTTGTAGGACATGAACTGGCACATCAATGGTTTGGCAATCTTGTAACAATGGAATGGTGGACACATCTCTGGCTGAATGAAGGATATGCATCTTTTGTGGAATTTCTTTGTGTAAATCATCTTTTCCCAGAATATGATATTTGGACTCAGTTTGTGACTGAAAACTACATTAGAGCATTGGAATTGGATTGCTTAAAAAATTCACACCCAATTGAGGTTCCTGTTGGCCATCCATCAGAAATTGATGAAATATTTGATGACATATCGTACAATAAGGGGGCATCTGTAATACGTATGTTACATAGATATATTGGCGATGAAGATTTTCGTAAGGGCATGAATATCTACCTAACTCGTCATCAGTACAAGAACACTTTCACTGAAGATTTGTGGGCAGCACTGGAAGAGGCGTCTAAAAAGCCTGTCGGAGCTGTTATGTCTACATGGACCAAACAGATGGGTTTCCCGATGGTTGAGGTTCAGTCAGAACAGCGGGGCTCCAATCGAGTATTAACATTAACTCAACGCAAATTCTGTGCGGATGGTAGTCAAGCAGATGACACTCTTTGGATGGTTCCAATATCCATATCAACGCAAGAACAACCTTCAAAGGTAGCTTTGTCTATGGTTTTAGAAAAGAGAACACAGGAAGTTGTATTGAAAAATGTAGCTCAAGACTCTTGGATTAAATTGAATCCAGGAACTGTGGGGTACTATCGCACACGGTACCCGGCAGAGCTGTTGGAGCAGCTGGTGCCGGCCATACGGGATGGCTCTCTGCCGCCGCTCGACCGCCTCGGACTACTGGACGACTGCTTCGCACTCGTGCAAGCGGGACACACGCACACTGCCGATTCTTTGAAACTTATGGAAGCATTCAGCAATGAAACAAATTTTACTGTGTGGTCGACCATCGCCAATTGTATGTCTAAGCTAAGTGCACTATTTTCTCAAACTGCTCTCGACAAACCCTTGAAAAATTACGGACGAAAGCTATTTTCAAACATAACCAAGAAATTGGGATGGGACGCGGAAGAGAAAGAAAGTCACCTCGACACTCTGCTCAGAAGCTTGGTGCTCAATAAGATGATTAGCTTTGAAGACCCTGACACCATTAAAGAAGCGAAAATTCGGTTTGAGAAGCACATTTCAGGCGAGCGGCCGCTGGCGGCGGACCTGCGCTCGGCGTGCTACCGCGCGGAGCTGGGCGGCGCCGACGAGCGCGTGTTCGAGCGGTTCCTGCAACTGTACCGCGCCGCCGACCTGCACGAGGAGAAGGACCGCGTGTCGCGGGCCCTGGGCGCCGTGCGGGACCCCGCGCTGCTCAGGCGCGTGCTCGACTTTGCCATCTCGGATGAAGTAAGATCGCAGGACACAGTTTTCGTTATCGTGTCAGTTGCAGTAAGCAGAAACGGTCGTGACCTGGCATGGCAGTTTTTCAAAGATCACTTCCAGGAATTCATAGAAAGATATCAGGGTGGATTCTTGTTGGCTCGGTTGGTGAAATCGACAACTGAAAACTTCGCGTCGGAGGCAGCAGCACAAGAGATTGAAGAGTTCTTCAGCACGCACGAGTCTCCCGGGGCGGAGCGCTCTGTTCAGCAGGCATTAGAGAGCGTTCGACTCAACGCGGCCTGGCTGCGCCGCGACCTCGCCTCCACCGCCACCTACCTGCACCCCTACCACTGA

Protein

MPENKPFQRLPNNVIPKHYALELIPNLEKFTFKGKTAVKVSIVNPTNVIVLNSLDLDLKNVKLQYNDGSNSAIIPSSVELSTTDETASIYFSESLLEGEATLYSEFTGEINDKMKGLYRSKYIAPNGEERYAAVTQFEATDARRCFPCWDEPAIKATFDITLQVPADRVALSNMPVKQEKIADNTRIIQFDTTPIMSTYLVAVVVGEYDYVEKKSNDGILVRVYTPVGKSKQGLFALEVAARVLPYYKDYFDIAYPLPKIDLIAIADFSAGAMENWGLVTYRETCLLVDEEHTSAVRRQWIALVVGHELAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVNHLFPEYDIWTQFVTENYIRALELDCLKNSHPIEVPVGHPSEIDEIFDDISYNKGASVIRMLHRYIGDEDFRKGMNIYLTRHQYKNTFTEDLWAALEEASKKPVGAVMSTWTKQMGFPMVEVQSEQRGSNRVLTLTQRKFCADGSQADDTLWMVPISISTQEQPSKVALSMVLEKRTQEVVLKNVAQDSWIKLNPGTVGYYRTRYPAELLEQLVPAIRDGSLPPLDRLGLLDDCFALVQAGHTHTADSLKLMEAFSNETNFTVWSTIANCMSKLSALFSQTALDKPLKNYGRKLFSNITKKLGWDAEEKESHLDTLLRSLVLNKMISFEDPDTIKEAKIRFEKHISGERPLAADLRSACYRAELGGADERVFERFLQLYRAADLHEEKDRVSRALGAVRDPALLRRVLDFAISDEVRSQDTVFVIVSVAVSRNGRDLAWQFFKDHFQEFIERYQGGFLLARLVKSTTENFASEAAAQEIEEFFSTHESPGAERSVQQALESVRLNAAWLRRDLASTATYLHPYH

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M1 family.

Uniprot

I3VR81   H9JQ68   A0A212F406   A0A2W1BLC5   A0A2H1W1L9   S4PRY9   + More
A0A067R998   A0A1W4WKI4   A0A2J7PQP5   E0VR15   A0A0K8TTN7   A0A0R1E0N1   B4QMF5   A0A0R1DUK5   A0A0R1DZS0   B4PD97   A0A0R1DU86   A0A0T6B7U7   A0A1L8E2T5   A0A0J9UC25   A0A1W4VU03   A0A1Y1LCB5   A0A1L8E2H5   A0A0J9RN50   A0A1W4W6K8   A0A1W4VU07   B4HVU3   A0A0J9RLM8   Q8IRH1   A0A1W4W577   E8NH92   Q8IRH0   A0A0Q5UCX3   B3NBB7   Q9W0E4   A0A0Q5U1R8   C8VUZ1   A0A0Q9WHK8   B4LCX5   A0A182QNL7   A0A0M3QW75   Q5TRG5   A0A182V0Y7   A0A3B0K9Q6   A0A3B0KIE7   W8ANG5   Q29FE8   B4H1F6   Q9GPG3   A0A0P4WFE2   A0A0R3P2G6   W8AJQ4   A0A0A1X6F9   A0A084VPY2   A0A0A1WT76   B4IXJ3   A0A0P9C240   A0A0P8YFL8   A0A0P8XT10   B3M8F9   A0A182RIS4   B4L8V4   A0A1I8PNJ7   B4MKU7   A0A1I8PNJ8   A0A034VU83   A0A034VSE7   A0A0L0CND7   A0A087ZTK0   A0A1I8MF11   A0A0K8VNJ6   T1PIH7   A0A1B6FHQ9   A0A1A9UGB1   A0A195CUU7   A0A1B0G3B9   K7JA89   A0A0C9PNN1   A0A1B6E9J3   A0A1B0B6Z2   A0A1A9YIB9   A0A2M4CK94   A0A2M4CKA0   E2BM61   A0A2M4CKS9   A0A1A9WA91   A0A0A9YBG9   A0A2M3Z0D2   A0A2M4A3P0   A0A2M4BCC3   A0A2M4BBR0   A0A2M4A3V7   A0A2M4BD12   E2A5M2   A0A182JLL4   A0A1D2N281   A0A158NA38   A0A0P4VXS7   A0A0J7L546   A0A195FRL0  

EC Number

3.4.11.-

Pubmed

19121390    22118469    28756777    23622113    24845553    20566863    + More
26369729    17994087    17550304    22936249    28004739    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    18057021    12364791    14747013    17210077    24495485    15632085    11819115    23185243    25830018    24438588    25348373    26108605    25315136    20075255    20798317    25401762    27289101    21347285    27129103   

EMBL

JQ061152    AFK85026.1    BABH01012063    AGBW02010462    OWR48461.1    KZ150049    + More
PZC74444.1    ODYU01005769    SOQ46969.1    GAIX01000390    JAA92170.1    KK852851    KDR15061.1    NEVH01022635    PNF18664.1    DS235442    EEB15821.1    GDAI01000090    JAI17513.1    CM000159    KRK00743.1    CM000363    EDX08812.1    KRK00741.1    KRK00746.1    EDW92845.1    KRK00742.1    LJIG01009289    KRT83377.1    GFDF01001145    JAV12939.1    CM002912    KMY96835.1    GEZM01063210    JAV69196.1    GFDF01001144    JAV12940.1    KMY96839.1    CH480817    EDW50058.1    KMY96838.1    AE014296    BT133253    AAN11480.1    AFB71128.1    BT125968    ADX35947.1    BT099693    AAN11481.1    ACV53057.1    CH954178    KQS43073.1    EDV50170.1    AAF47504.1    KQS43071.1    BT099737    ACV53871.1    CH940647    KRF84040.1    EDW68836.2    AXCN02000881    CP012525    ALC43653.1    AAAB01008960    EAL39899.3    OUUW01000009    SPP84860.1    SPP84861.1    GAMC01020567    JAB85988.1    CH379067    EAL31307.3    CH479202    EDW30133.1    AF327435    AAG48733.1    GDRN01034234    JAI67458.1    KRT07386.1    GAMC01020568    JAB85987.1    GBXI01007570    JAD06722.1    ATLV01015079    KE525001    KFB40026.1    GBXI01012491    JAD01801.1    CH916366    EDV96430.1    CH902618    KPU77721.1    KPU77720.1    KPU77719.1    EDV38894.1    CH933816    EDW17129.2    CH963847    EDW72803.2    GAKP01013557    JAC45395.1    GAKP01013558    JAC45394.1    JRES01000254    KNC32934.1    GDHF01011858    JAI40456.1    KA647733    AFP62362.1    GECZ01020049    JAS49720.1    KQ977276    KYN04456.1    CCAG010013759    AAZX01015428    GBYB01002728    JAG72495.1    GEDC01015936    GEDC01002690    JAS21362.1    JAS34608.1    JXJN01009324    GGFL01001604    MBW65782.1    GGFL01001602    MBW65780.1    GL449158    EFN83187.1    GGFL01001603    MBW65781.1    GBHO01016724    JAG26880.1    GGFM01001190    MBW21941.1    GGFK01002115    MBW35436.1    GGFJ01001327    MBW50468.1    GGFJ01001319    MBW50460.1    GGFK01002114    MBW35435.1    GGFJ01001798    MBW50939.1    GL437023    EFN71265.1    LJIJ01000285    ODM99382.1    ADTU01009957    GDKW01001138    JAI55457.1    LBMM01000742    KMQ97594.1    KQ981305    KYN42922.1   

Proteomes

UP000005204    UP000007151    UP000027135    UP000192223    UP000235965    UP000009046    + More
UP000002282    UP000000304    UP000192221    UP000001292    UP000000803    UP000008711    UP000008792    UP000075886    UP000092553    UP000007062    UP000075903    UP000268350    UP000001819    UP000008744    UP000030765    UP000001070    UP000007801    UP000075900    UP000009192    UP000095300    UP000007798    UP000037069    UP000005203    UP000095301    UP000078200    UP000078542    UP000092444    UP000002358    UP000092460    UP000092443    UP000008237    UP000091820    UP000000311    UP000075880    UP000094527    UP000005205    UP000036403    UP000078541   

PRIDE

I3VR81    H9JQ68    Q8IRH1    E8NH92    Q8IRH0    Q9W0E4    + More
C8VUZ1    Q9GPG3    A0A087ZTK0   

Pfam

PF01433   Peptidase_M1        + More
PF11838   ERAP1_C

Interpro

IPR042097   Aminopeptidase_N-like_N        + More
IPR024571   ERAP1-like_C_dom       
IPR014782   Peptidase_M1_dom       
IPR034016   M1_APN-typ       
IPR001930   Peptidase_M1       

Gene 3D

2.60.40.1730    

CDD

cd09601  M1_APN_2

ProteinModelPortal

I3VR81   H9JQ68   A0A212F406   A0A2W1BLC5   A0A2H1W1L9   S4PRY9   + More
A0A067R998   A0A1W4WKI4   A0A2J7PQP5   E0VR15   A0A0K8TTN7   A0A0R1E0N1   B4QMF5   A0A0R1DUK5   A0A0R1DZS0   B4PD97   A0A0R1DU86   A0A0T6B7U7   A0A1L8E2T5   A0A0J9UC25   A0A1W4VU03   A0A1Y1LCB5   A0A1L8E2H5   A0A0J9RN50   A0A1W4W6K8   A0A1W4VU07   B4HVU3   A0A0J9RLM8   Q8IRH1   A0A1W4W577   E8NH92   Q8IRH0   A0A0Q5UCX3   B3NBB7   Q9W0E4   A0A0Q5U1R8   C8VUZ1   A0A0Q9WHK8   B4LCX5   A0A182QNL7   A0A0M3QW75   Q5TRG5   A0A182V0Y7   A0A3B0K9Q6   A0A3B0KIE7   W8ANG5   Q29FE8   B4H1F6   Q9GPG3   A0A0P4WFE2   A0A0R3P2G6   W8AJQ4   A0A0A1X6F9   A0A084VPY2   A0A0A1WT76   B4IXJ3   A0A0P9C240   A0A0P8YFL8   A0A0P8XT10   B3M8F9   A0A182RIS4   B4L8V4   A0A1I8PNJ7   B4MKU7   A0A1I8PNJ8   A0A034VU83   A0A034VSE7   A0A0L0CND7   A0A087ZTK0   A0A1I8MF11   A0A0K8VNJ6   T1PIH7   A0A1B6FHQ9   A0A1A9UGB1   A0A195CUU7   A0A1B0G3B9   K7JA89   A0A0C9PNN1   A0A1B6E9J3   A0A1B0B6Z2   A0A1A9YIB9   A0A2M4CK94   A0A2M4CKA0   E2BM61   A0A2M4CKS9   A0A1A9WA91   A0A0A9YBG9   A0A2M3Z0D2   A0A2M4A3P0   A0A2M4BCC3   A0A2M4BBR0   A0A2M4A3V7   A0A2M4BD12   E2A5M2   A0A182JLL4   A0A1D2N281   A0A158NA38   A0A0P4VXS7   A0A0J7L546   A0A195FRL0  

PDB

4KXD     E-value=6.38405e-132,     Score=1209

KEGG

101743240    K08776 puromycin-sensitive aminopeptidase [EC:3.4.11.-] | (RefSeq) puromycin-sensitive aminopeptidas

GO

GO:0008237   GO:0004177   GO:0008270   GO:0042277   GO:0043171   GO:0005737   GO:0006508   GO:0070006   GO:0006468   GO:0006813   GO:0008076   GO:0005216   GO:0006811   GO:0016020   GO:0005634   GO:0006260  

Length:

865

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01069

Exp number, first 60 AAs:

0.00201

Total prob of N-in:

0.00041

outside

1  -  865

 

 

Pi

216.332509

Theta

159.640394

Tajima's D

1.264571

CLR

0

CSRT

0.731563421828909

Interpretation

Uncertain