Gene

KWMTBOMO06561  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011822

Annotation

PREDICTED:_nucleolar_GTP-binding_protein_2_[Bombyx_mori]

Location

Bomo_Chr11(-):10535436-10540714      View in EpiBrowser

Full name

Nucleolar GTP-binding protein 2      

Location in the cell

Nuclear   Reliability : 3.932

CDS

ATGGGAAAAGTTCGGTCGACTCCGGGTGCTCCCCGGAAACAAGGGTTTAATAAGTCTGGGCATTCAATGAACCCTGATCGACCCACAGAGGGTTTGAAAGGCGTAGGCAACCCGAGATCAAAAGGAACAATTAAGAGACTACAGATGTACCGAAACTTTAAGGCAAAAAGGGATAAAACCGGAAAAATTCTAACGCCAGCACCCTTTCAAGGTTGGTTACCATCAGGCACACAGGCACGCGTTGAACCAAACCAAAAATGGTTTGGAAATTCAAGAGTTATATCACAGAATGCATTGCAAAAATTTCAAGAGGAGTTTGGAGCTGCTGTAAGAAATCCATATCAAGTGATCATGAAACCAACGAATTTGCCCATAACATTACTTAATGAAAAAGCAAAAAATGCAAGAGTTCACCTTCTAGATACTGAAGGTTTTGATAGGACATTTGGTCCTAAAAAGCAGAGAAAAAGAGTAAATTTGAAATTCAGCGATCTAAATGATTTGCATAAAGCGGTAGAAGAAAGCTCTGAGAAATATGATGAAACTAAAGATATTGACAGAGTCCGTGAAGATTCAGGTGTAAAAGAAGGACAAAGAGACTGGGTTTTTGGGGCTGGAATGAGTAGGAGGATATGGAATGAATTATACAAAGTAATTGACTCATCAGATGTGTTATTGCAAGTTCTTGATGCAAGAGATCCCATTGGGACAAGAAGTCCTTATGTTGAAAAATTTTTGAGAGAAGAAAAACCCCATAAACATCTTATATTTATCTTGAATAAAGTTGATTTGGTACCAAATTGGGTGACACAGAGATGGGTCGCAATTCTCAGTGCTGAGTATCCAACGATAGCATTTCATGCTTCATTAACACATCCTTTTGGTAAAGGCTCACTTATAAATTTACTACGTCAATTTGGAAAGTTGCACATTGACAAGAAACAAATAAGTGTAGGTTTTATTGGTTATCCAAATGTAGGAAAATCATCTGTGATTAATACTTTAAGGTCTAAAAAAGTTTGTAAAGTAGCCCCAATTGCTGGTGAAACAAAAGTTTGGCAGTATATCACCTTAATGAAGAGAATATTCTTGATTGATTGTCCGGGTGTTGTTTATCCATCAGCTGAAACAGACACAGAGAAAGTATTAAAAGGAGTAGTGAGGGTTGAGCTGGTACAAAATCCTGATGATTATATTGAAGAAGTTATTAAAAGAGTCAGAAAGGAGTACTTAGTGAAGACTTATAAAGTAGATGGATGGGAAACAGCTACTGAATTTTTGGAAAAACTTGCAGCAAGAACTGGAAAATTGTTAAAAAAAGGTGAACCTGATGTTAACCAAGTTGCAAGGATGGTCCTTAATGATTGGCAGAGAGGTAAATTGCCTTTCTATGTAGCTCCAGAGGGATTTGAAGTACCACTCTCTAAGCAAACACAAGATGAAAAAACTGTTGAAGTTGCAAACGAAGAAGAAAAGATAACAACTGAGACTAAAGCAGAAAAAAATAAACCTGAAACTAAAACGGACGATAGTGATAAACCTATTGTTCATATAAGTAATTTGATGATTGCACAAGATTTTGCTAAGATAAGAGTTGGATTAAAATTTGACAACAATGAAGACATAAAACCTTTAGGTAAAATAGTAATATCAGAAGACATTAAAGTTAAAGATGGTGAGAGTGTCCTAAATTCATCAGTAATTGAAAGTGATGATGAAATAGAAAAAAATGATGATGAAGACGACTCTTCAGATATTAGCGAATTCTATAGTAATGATGAAAAAGAAACTTCTGATGTGGAAGACCATTTGACTAATGATCCCGAAACAATTAAAGAAATGAAGAGAAAGAAATTAGAAGCTGCCAGTGGAGCATTTACTGTAGAAGAAGTAGCACAAAGTGGAAAGAAACACAAAATTAACGATCAGAGTAATGAGTTTTCAAATAAGAAAATGACTGCAAAGAAACGTAGAGCCATAGAAAGAGCTAACCGCCGCACTAAAACAGGAAGCAACTTCTATGAAGTGTCTAATATGTCATCAGGGAGTGAGAGCGACGAAGACTATGTACCTGGAGAACCGGAAAAACTATCTGAAGAGGAATCTGCTGATGATGAAACTGAAAAACAATACGAACATGAAGTTGAAGGCAAAATAAAAAAACGGAAAGCTACAGCTGAAAAAATAAATAAAGTAAAGAAGTCTAGAAAGAGCCAAAATGATACAATAATACAAGTTACATCAGAAAAAGATAAAACACCTGAACCAATAGTTGACTCTGAACAAGAGAAAAAACGAGAAGAAGATTTGTGGGCGAAGTTTCTTGAAGGAACCGATTCAAAGCCTAAACCAGTTCTTAAAGAAAAAAGTGTTGATTTAGTTACCAACCCGGAAAGGTCAAGCAATAATACGGTAAATTATAAGAAAACAAATGATGATGATGCCAAAGAAAAAGAAAGAAGGATTTTTGAATTTGCTGGTGAAAAAATTGTAGTAGAAAATAATGTCATAAAAGAGCGGTTGAAAGTTGACGAAACATCTATGGAAGCCATTAAATCTGATGGTTCCCAAAATCAAACATCAGATATAACAGCTCAGTCATCAAGTAGTGCAAAACCTGGTGGACTTTCTAATGTTTTGGGTCAACTAAATAAGAAAAACAGATTGTCTACCTTAGAAAAATCGAAATTAGATTGGGTCACTTACAAGCACGAAGAAGGAATTGACGATGAAATACAAAGTCACAACAAAGGCAAACAAGGATTTTTAGATCGTCGTGATTTCCTAGAAAGAGCTGATATGAGGCAGTATGAAATCGAAAGAGAACTGAGGACAAGTCGCAGAAGCAATCGTTAA

Protein

MGKVRSTPGAPRKQGFNKSGHSMNPDRPTEGLKGVGNPRSKGTIKRLQMYRNFKAKRDKTGKILTPAPFQGWLPSGTQARVEPNQKWFGNSRVISQNALQKFQEEFGAAVRNPYQVIMKPTNLPITLLNEKAKNARVHLLDTEGFDRTFGPKKQRKRVNLKFSDLNDLHKAVEESSEKYDETKDIDRVREDSGVKEGQRDWVFGAGMSRRIWNELYKVIDSSDVLLQVLDARDPIGTRSPYVEKFLREEKPHKHLIFILNKVDLVPNWVTQRWVAILSAEYPTIAFHASLTHPFGKGSLINLLRQFGKLHIDKKQISVGFIGYPNVGKSSVINTLRSKKVCKVAPIAGETKVWQYITLMKRIFLIDCPGVVYPSAETDTEKVLKGVVRVELVQNPDDYIEEVIKRVRKEYLVKTYKVDGWETATEFLEKLAARTGKLLKKGEPDVNQVARMVLNDWQRGKLPFYVAPEGFEVPLSKQTQDEKTVEVANEEEKITTETKAEKNKPETKTDDSDKPIVHISNLMIAQDFAKIRVGLKFDNNEDIKPLGKIVISEDIKVKDGESVLNSSVIESDDEIEKNDDEDDSSDISEFYSNDEKETSDVEDHLTNDPETIKEMKRKKLEAASGAFTVEEVAQSGKKHKINDQSNEFSNKKMTAKKRRAIERANRRTKTGSNFYEVSNMSSGSESDEDYVPGEPEKLSEEESADDETEKQYEHEVEGKIKKRKATAEKINKVKKSRKSQNDTIIQVTSEKDKTPEPIVDSEQEKKREEDLWAKFLEGTDSKPKPVLKEKSVDLVTNPERSSNNTVNYKKTNDDDAKEKERRIFEFAGEKIVVENNVIKERLKVDETSMEAIKSDGSQNQTSDITAQSSSSAKPGGLSNVLGQLNKKNRLSTLEKSKLDWVTYKHEEGIDDEIQSHNKGKQGFLDRRDFLERADMRQYEIERELRTSRRSNR

Description

GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.

Similarity

Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.

Uniprot

H9JQL6   A0A2H1WTS7   A0A194QP10   A0A212ENS7   A0A0L7KYK9   A0A3S2LZU6   + More
A0A2W1BP41   A0A194PVE3   D6WJC1   A0A0L0CJE7   A0A1I8P4P6   T1PF30   A0A034WHQ6   W8CB99   Q7JXU4   J3JVZ3   B4P5E7   B3NMJ4   B4QB97   B4HMW9   A0A0K8UPR7   A0A0A1XT38   A0A1W4V0Z7   B3MIH6   B4GAZ5   B4MQM5   Q291A7   A0A3B0JIX0   A0A0M4ETX7   B4KM04   A0A1A9WDT1   A0A1L8DHP3   A0A1Y1LD66   B4LQ36   A0A0L7REG8   B4J4P9   A0A1A9ZWT3   D3TMP3   A0A182TWD3   Q7PSR2   A0A154NWH9   A0A182JQC0   A0A1A9VGQ3   A0A182MEC6   A0A1Q3F0X0   A0A182WFN2   A0A182RLL8   A0A1A9XWU4   A0A182WYV6   A0A1B0BB01   A0A182JGS5   A0A182HY77   A0A182LHD1   A0A182Y6X9   A0A2M4A8A4   A0A2A3EGG7   A0A195D365   A0A2M4A8A8   A0A2M4BG14   A0A2M4BG33   A0A195BU46   A0A1S4F477   A0A1B0DG85   A0A0C9RNC3   A0A336LUL1   A0A151X249   A0A026WF81   A0A195E4E8   B0W2K4   Q17FU3   U5EVC1   A0A182G2Z4   A0A088AFU3   E9J5F8   A0A0J7KK22   A0A310SCU9   E0VAY3   A0A1B6LD70  

Pubmed

19121390    26354079    22118469    26227816    28756777    18362917    + More
19820115    26108605    25315136    25348373    24495485    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22516182    23537049    17994087    17550304    22936249    25830018    15632085    28004739    20353571    12364791    20966253    25244985    24508170    30249741    17510324    26483478    21282665    20566863   

EMBL

BABH01012126    ODYU01010951    SOQ56382.1    KQ461190    KPJ07252.1    AGBW02013617    + More
OWR43138.1    JTDY01004307    KOB68307.1    RSAL01000094    RVE47882.1    KZ149971    PZC76041.1    KQ459590    KPI97292.1    KQ971343    EFA04454.1    JRES01000408    KNC31609.1    KA646765    AFP61394.1    GAKP01004768    JAC54184.1    GAMC01000649    JAC05907.1    AE013599    AF315579    AY089700    AAF57834.1    AAL26879.1    AAL90438.1    APGK01040748    BT127411    KB740984    KB631904    AEE62373.1    ENN76265.1    ERL87093.1    CM000158    EDW91778.1    CH954179    EDV54933.1    CM000362    CM002911    EDX07521.1    KMY94624.1    CH480816    EDW48319.1    GDHF01023738    JAI28576.1    GBXI01000095    JAD14197.1    CH902619    EDV37024.1    CH479181    EDW32097.1    CH963849    EDW74414.1    CM000071    EAL25205.2    OUUW01000001    SPP75260.1    CP012524    ALC41050.1    CH933808    EDW10793.1    GFDF01008106    JAV05978.1    GEZM01060903    JAV70828.1    CH940648    EDW60359.1    KQ414609    KOC69337.1    CH916367    EDW00595.1    CCAG010018327    EZ422695    ADD18971.1    AAAB01008816    EAA05176.5    KQ434775    KZC04055.1    AXCM01001434    GFDL01013839    JAV21206.1    JXJN01011233    APCN01004503    GGFK01003674    MBW36995.1    KZ288254    PBC30873.1    KQ976885    KYN07306.1    GGFK01003688    MBW37009.1    GGFJ01002772    MBW51913.1    GGFJ01002770    MBW51911.1    KQ976408    KYM91139.1    AJVK01033592    AJVK01033593    AJVK01033594    GBYB01005487    GBYB01009855    JAG75254.1    JAG79622.1    UFQS01000207    UFQT01000207    SSX01342.1    SSX21722.1    KQ982580    KYQ54511.1    KK107250    QOIP01000002    EZA54341.1    RLU25429.1    KQ979657    KYN19956.1    DS231827    EDS29312.1    CH477268    EAT45408.1    GANO01001924    JAB57947.1    JXUM01040646    KQ561253    KXJ79211.1    GL768153    EFZ11951.1    LBMM01006418    KMQ90622.1    KQ777347    OAD52113.1    DS235019    EEB10539.1    GEBQ01018356    JAT21621.1   

Proteomes

UP000005204    UP000053240    UP000007151    UP000037510    UP000283053    UP000053268    + More
UP000007266    UP000037069    UP000095300    UP000095301    UP000000803    UP000019118    UP000030742    UP000002282    UP000008711    UP000000304    UP000001292    UP000192221    UP000007801    UP000008744    UP000007798    UP000001819    UP000268350    UP000092553    UP000009192    UP000091820    UP000008792    UP000053825    UP000001070    UP000092445    UP000092444    UP000075902    UP000007062    UP000076502    UP000075881    UP000078200    UP000075883    UP000075920    UP000075900    UP000092443    UP000076407    UP000092460    UP000075880    UP000075840    UP000075882    UP000076408    UP000242457    UP000078542    UP000078540    UP000092462    UP000075809    UP000053097    UP000279307    UP000078492    UP000002320    UP000008820    UP000069940    UP000249989    UP000005203    UP000036403    UP000009046   

PRIDE

H9JQL6   

Pfam

PF01926   MMR_HSR1        + More
PF08153   NGP1NT
PF07572   BCNT
PF08311   Mad3_BUB1_I
PF13632   Glyco_trans_2_3

Interpro

IPR011421   BCNT-C        + More
IPR027417   P-loop_NTPase       
IPR024929   NOG2       
IPR030378   G_CP_dom       
IPR012971   NOG2_N_dom       
IPR006073   GTP_binding_domain       
IPR023179   GTP-bd_ortho_bundle_sf       
IPR013212   Mad3/Bub1_I       
IPR017441   Protein_kinase_ATP_BS       
IPR011009   Kinase-like_dom_sf       
IPR000719   Prot_kinase_dom       
IPR001173   Glyco_trans_2-like       
IPR029044   Nucleotide-diphossugar_trans       

SUPFAM

SSF52540   SSF52540        + More
SSF56112   SSF56112       
SSF53448   SSF53448       

Gene 3D

1.10.1580.10     3.90.550.10    

ProteinModelPortal

H9JQL6   A0A2H1WTS7   A0A194QP10   A0A212ENS7   A0A0L7KYK9   A0A3S2LZU6   + More
A0A2W1BP41   A0A194PVE3   D6WJC1   A0A0L0CJE7   A0A1I8P4P6   T1PF30   A0A034WHQ6   W8CB99   Q7JXU4   J3JVZ3   B4P5E7   B3NMJ4   B4QB97   B4HMW9   A0A0K8UPR7   A0A0A1XT38   A0A1W4V0Z7   B3MIH6   B4GAZ5   B4MQM5   Q291A7   A0A3B0JIX0   A0A0M4ETX7   B4KM04   A0A1A9WDT1   A0A1L8DHP3   A0A1Y1LD66   B4LQ36   A0A0L7REG8   B4J4P9   A0A1A9ZWT3   D3TMP3   A0A182TWD3   Q7PSR2   A0A154NWH9   A0A182JQC0   A0A1A9VGQ3   A0A182MEC6   A0A1Q3F0X0   A0A182WFN2   A0A182RLL8   A0A1A9XWU4   A0A182WYV6   A0A1B0BB01   A0A182JGS5   A0A182HY77   A0A182LHD1   A0A182Y6X9   A0A2M4A8A4   A0A2A3EGG7   A0A195D365   A0A2M4A8A8   A0A2M4BG14   A0A2M4BG33   A0A195BU46   A0A1S4F477   A0A1B0DG85   A0A0C9RNC3   A0A336LUL1   A0A151X249   A0A026WF81   A0A195E4E8   B0W2K4   Q17FU3   U5EVC1   A0A182G2Z4   A0A088AFU3   E9J5F8   A0A0J7KK22   A0A310SCU9   E0VAY3   A0A1B6LD70  

PDB

6N8J     E-value=6.77999e-126,     Score=1157

KEGG

101746403    K14537 nuclear GTP-binding protein | (RefSeq) nucleolar GTP-binding protein 2

PATHWAY

03008    Ribosome biogenesis in eukaryotes - Bombyx mori (domestic silkworm)

GO

GO:0005525   GO:0005730   GO:0003924   GO:0001745   GO:0005654   GO:0004672   GO:0005524   GO:0016021   GO:0005515   GO:0051536   GO:0016791   GO:0006812   GO:0015299   GO:0006419   GO:0015923   GO:0005634   GO:0006260  

PANTHER

PTHR11089:SF9  

Subcellular location

  

Length:

951

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00510999999999999

Exp number, first 60 AAs:

1e-05

Total prob of N-in:

0.00026

outside

1  -  951

 

 

Pi

284.796923

Theta

210.948372

Tajima's D

1.265875

CLR

0.333593

CSRT

0.733963301834908

Interpretation

Uncertain