Gene

KWMTBOMO06522

Pre Gene Modal

BGIBMGA011845

Annotation

putative_protein_phosphatases_pp1_regulatory_subunit_[Danaus_plexippus]

Location

Bomo_Chr11(-):9743769-9751289      View in EpiBrowser

Full name

Dynein regulatory complex subunit 3      

Alternative Name

Leucine-rich repeat-containing protein 48

Location in the cell

Cytoplasmic   Reliability : 4.083

CDS

ATGACCGAGAAGAGATCATTGAATAGCCTTGTAATATATCCAGACATCGAGCCTGGTGTCATTGATAATGCGATGATCATACGATGTATACTTGAGTACGGGCCTACTGAAGAAGCAGGAAGACTTTTTGCCGAAGAAGGAGTACATTTGGATGAAGCTCAAGTAGTTCGACTTGAATTTCAAAATATTTTAAGAATCGATCATCTATGGATGTTGAAATCTTTAAGGAAATTAACTTTAGCTCATAATTTAATAGAAAAAATAGAAAATCTGGATCAACTTACTGGCCTGAATGAACTAGATTTATCGTTTAACAAAATTGAAAAGATTGAAAACTTGGATAAACTCGTAAATTTGGAAATCCTTACGTTGTTTCATAACAGAATCAGGAAACTGGAAAACATGGAATTGCTTGAAAAATTGCTTGTATTTAGTATTGGTGATAATATAATAGAGGATTATAAAGAAATGGCCTACCTCCGCAGATTCCGTTTTCTTCGTTCAGTGAGCTTCAAGGGAAACCCATGCTGCGACGACCCTATGGCTTATCAGTTTATCAAATCAGCTTTAACCAGAGTTACATATCTTGATTACAAAATCGTCACGGAAGCAGAAAGAGAAGACGGTAGAGCTTTGTTTAGAGGTGTTCTTCGAAAATTAGATGAAGCTGACGAGAAATCGGAAAATGAAAGATTAGCCAAAGAGGACTACGAAGCTAGGGTGAAATTTTATGCGTTATCCTTCGTCGAATACTTAAGCGGGCCGGAACTTCTCGAGGCAATGTTCGAAAAGGACCCTGATGGATCTTTACTTCTGAAGATGGGCGGTGAACTGAATGGATTTTTTGAACAATATAAAGAACAATACGTGGAAACGATGGCGGGCTTGGTTGAATTCGCTTTAGAAGCCTATAACGCGAGACAGTATGAAATTAAACTATTCAAAGATTTAGTTAATGATGCGCTGGAAGAGAGCGTCAAGAAAAGCAAAGAGATCATTATTGAATACGAAAACAAAAAGAGGCCGCTTGTAAATGAAATGCAAGAATTCATAAACAGGTTCACGACGAAGCAAGCTACCATAGAGGAGCTTGAGCCGTTGATAGTTGACCTCGGCGAGACCTTCAATGAGGTCCTCTACCACCTGTGGAAGAGTCTCATGACCATAGAGATGCAGCTCTACGAGCAGTGTGAGGAATCTCGCGTACAATTTTCTGTTAACATAACGGAAATGGTAACGAAACTGTTGGAGGTATCTCGTAACGCATTCGGAGCGTGGCGCGAACAAGAGGGCGTCTGGTCTATGAGACAGTTCGAGGCGCTGTCAAAGCTCCTTGGGAATAAGCTCATCTTGGGAGACGTACCCCCAGAGTTATTTGAGGTGATGATGGATCGAGATTTAATGATGAATTTAGTGGCTCAATCCTCGGATAACCACATGCGTTTTATTGATGGACGCGAGGATTTGCTCATGACCCGTGCCAACAACTGGCGAGATGAACTTGTACAAGGCACTAATGATAACGAAGTAAAGCGTAATCGAGATCGTATATTAGAGATAAATTACTACATAGACAATCAAAGAGAGGAGTGGACTGATATGCAGATGGGACTTACTGAAATAGTAGACCCGGAGACGGTCGCCTTACTTGGTGATGACTTTTAA

Protein

MTEKRSLNSLVIYPDIEPGVIDNAMIIRCILEYGPTEEAGRLFAEEGVHLDEAQVVRLEFQNILRIDHLWMLKSLRKLTLAHNLIEKIENLDQLTGLNELDLSFNKIEKIENLDKLVNLEILTLFHNRIRKLENMELLEKLLVFSIGDNIIEDYKEMAYLRRFRFLRSVSFKGNPCCDDPMAYQFIKSALTRVTYLDYKIVTEAEREDGRALFRGVLRKLDEADEKSENERLAKEDYEARVKFYALSFVEYLSGPELLEAMFEKDPDGSLLLKMGGELNGFFEQYKEQYVETMAGLVEFALEAYNARQYEIKLFKDLVNDALEESVKKSKEIIIEYENKKRPLVNEMQEFINRFTTKQATIEELEPLIVDLGETFNEVLYHLWKSLMTIEMQLYEQCEESRVQFSVNITEMVTKLLEVSRNAFGAWREQEGVWSMRQFEALSKLLGNKLILGDVPPELFEVMMDRDLMMNLVAQSSDNHMRFIDGREDLLMTRANNWRDELVQGTNDNEVKRNRDRILEINYYIDNQREEWTDMQMGLTEIVDPETVALLGDDF

Description

Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.

Subunit

Component of the nexin-dynein regulatory complex (N-DRC). Interacts with TCTE1/DRC5.

Similarity

Belongs to the DRC3 family.

Keywords

Cell projection   Cilium   Coiled coil   Complete proteome   Cytoplasm   Cytoskeleton   Flagellum   Leucine-rich repeat   Reference proteome   Repeat   Alternative splicing   Polymorphism  

Feature

chain  Dynein regulatory complex subunit 3
splice variant  In isoform 2.
sequence variant  In dbSNP:rs8072048.

Uniprot

H9JQN9   A0A3S2PK34   A0A212FP70   A0A194PW71   A0A2W1BVE7   A0A2A4J784   + More
A0A0L7KKW0   D6WHD8   A0A182GKN6   Q17BZ8   A0A336MCL9   B0X2M1   A0A182YQV4   H2Z571   A0A0K8URK1   A0A1S3S2C1   A0A034VRY8   E0VR18   A0A1S4H304   A0A182WXJ0   D1LX59   A0A182PTL3   A0A182HQX4   H2Z573   A0A151P459   B3RMW3   A0A084VWW0   A0A182NNP2   N6TGM6   D6PAM7   W4XT49   A0A1U7S3Y1   A0A3L8D8U9   A0A3Q0GQA5   K7FW75   A0A026WW88   F7C761   A0A182FN11   F7AMV0   A0A2A3EK81   A0A1I8Q7I6   A0A3B4CJZ4   A0A1S3I9V2   A0A2G8L3T2   W5MQR2   A0A2Y9HFA9   A0A182R1M1   A0A1L8EYS6   A0A3S1A630   R7V961   A0A2U3YT09   A0A1B0BLR1   W8BH80   A0A2K5QKU5   A0A1W5ABW9   A0A2Y9IEX0   F4WFX7   A9Z1C6   A0A3Q7PVV1   M3XLS6   A6QQM3   A0A2U3WA38   B7FEZ6   A0A2K6S285   G3QDZ8   A0A0L0CH63   Q5XI54   F6UPM5   A0A3Q7TJB2   A0A2Y9RA10   B7FEZ7   A0A2J8J374   A0A384BQ03   A0A3Q7Y663   A0A3M7T3F2   H0V1B6   B7FEZ8   B7FEZ4   A0A3Q1MEH8   A0A2K6EUJ2   V8PDV7   C3Z6W3   A0A1S3F7P7   Q95V50   G2HG10   B3DM08   A0A1S2ZXQ1   W5UCE8   W5NT62   Q9H069   A0A2J8RIA4   B3KSC6   A0A1W4WA79   A0A3P8ZP13   A0NG27   A0A2T7PVG3   H2NSX6  

Pubmed

19121390    22118469    26354079    28756777    26227816    18362917    + More
19820115    26483478    17510324    25244985    25348373    20566863    12364791    22293439    18719581    24438588    23537049    19011613    30249741    17381049    24508170    18464734    12481130    15114417    29023486    27762356    23254933    24495485    21719571    22398555    26108605    15489334    17495919    16136131    30375419    21993624    19393038    24297900    18563158    10731132    11687639    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    21484476    23127152    20809919    11230166    14702039    23354437    27120127    25069045   

EMBL

BABH01012181    RSAL01000010    RVE53689.1    AGBW02003612    OWR55525.1    KQ459590    + More
KPI97248.1    KZ149984    PZC75733.1    NWSH01002655    PCG67739.1    JTDY01009186    KOB64008.1    KQ971321    EFA00104.1    JXUM01070289    KQ562597    KXJ75518.1    CH477314    EAT43821.1    UFQS01000652    UFQT01000652    SSX05788.1    SSX26147.1    DS232291    EDS39244.1    GDHF01023005    JAI29309.1    GAKP01012876    JAC46076.1    DS235442    EEB15824.1    AAAB01008980    GU076036    ACY92565.1    APCN01001609    AKHW03001118    KYO43793.1    DS985242    EDV27345.1    ATLV01017759    KE525185    KFB42454.1    APGK01039004    KB740966    KB632186    ENN76938.1    ERL89708.1    GU937420    ADF80167.1    AAGJ04146428    QOIP01000011    RLU16950.1    AGCU01109845    AGCU01109846    AGCU01109847    KK107078    EZA60297.1    EAAA01001651    KZ288230    PBC31596.1    MRZV01000229    PIK54924.1    AHAT01013724    CM004482    OCT64478.1    RQTK01000234    RUS83695.1    AMQN01005475    KB296106    ELU12260.1    JXJN01016540    GAMC01017556    GAMC01017554    JAB88999.1    GL888128    EGI66744.1    EU334139    GU937418    ABY19295.2    ADF80165.1    AEYP01089327    AEYP01089328    BC149900    AAI49901.1    BK006433    DAA06417.1    CABD030039170    CABD030039171    JRES01000384    KNC31753.1    BC083838    BK006434    DAA06418.1    AACZ04059836    AACZ04059837    AACZ04059838    NBAG03000529    PNI17230.1    PNI17232.1    REGN01000363    RNA42467.1    AAKN02045137    BK006435    DAA06419.1    BK006431    DAA06415.1    AZIM01000256    ETE72193.1    GG666590    EEN51559.1    AF427495    CP007106    AAL25119.1    EAL24528.3    AK305674    BAK62668.1    BC167655    AAI67655.1    JT411703    AHH39565.1    AMGL01018301    AMGL01018302    AL136926    AK293011    BC040276    BC047873    BC050419    BC050665    NDHI03003690    PNJ08245.1    PNJ08246.1    AK093317    BAG52688.1    EAU76121.2    PZQS01000001    PVD37412.1    ABGA01117140    ABGA01117141    ABGA01117142    ABGA01117143    ABGA01117144   

Proteomes

UP000005204    UP000283053    UP000007151    UP000053268    UP000218220    UP000037510    + More
UP000007266    UP000069940    UP000249989    UP000008820    UP000002320    UP000076408    UP000007875    UP000087266    UP000009046    UP000076407    UP000075885    UP000075840    UP000050525    UP000009022    UP000030765    UP000075884    UP000019118    UP000030742    UP000007110    UP000189705    UP000279307    UP000007267    UP000053097    UP000002279    UP000069272    UP000008144    UP000242457    UP000095300    UP000261440    UP000085678    UP000230750    UP000018468    UP000248481    UP000075900    UP000186698    UP000271974    UP000014760    UP000245341    UP000092460    UP000233040    UP000192224    UP000248482    UP000007755    UP000286641    UP000000715    UP000245340    UP000233220    UP000001519    UP000037069    UP000002494    UP000002280    UP000286640    UP000248480    UP000002277    UP000261680    UP000286642    UP000276133    UP000005447    UP000009136    UP000233160    UP000001554    UP000081671    UP000000803    UP000079721    UP000221080    UP000002356    UP000005640    UP000192221    UP000265140    UP000007062    UP000245119    UP000001595   

PRIDE

H9JQN9    Q5XI54    Q95V50    Q9H069    B3KSC6   

Pfam

PF12799   LRR_4        + More
PF00378   ECH_1

Interpro

IPR032675   LRR_dom_sf        + More
IPR001611   Leu-rich_rpt       
IPR025875   Leu-rich_rpt_4       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR001753   Enoyl-CoA_hydra/iso       
IPR029045   ClpP/crotonase-like_dom_sf       

SUPFAM

SSF52096   SSF52096       

Gene 3D

3.80.10.10    

ProteinModelPortal

H9JQN9   A0A3S2PK34   A0A212FP70   A0A194PW71   A0A2W1BVE7   A0A2A4J784   + More
A0A0L7KKW0   D6WHD8   A0A182GKN6   Q17BZ8   A0A336MCL9   B0X2M1   A0A182YQV4   H2Z571   A0A0K8URK1   A0A1S3S2C1   A0A034VRY8   E0VR18   A0A1S4H304   A0A182WXJ0   D1LX59   A0A182PTL3   A0A182HQX4   H2Z573   A0A151P459   B3RMW3   A0A084VWW0   A0A182NNP2   N6TGM6   D6PAM7   W4XT49   A0A1U7S3Y1   A0A3L8D8U9   A0A3Q0GQA5   K7FW75   A0A026WW88   F7C761   A0A182FN11   F7AMV0   A0A2A3EK81   A0A1I8Q7I6   A0A3B4CJZ4   A0A1S3I9V2   A0A2G8L3T2   W5MQR2   A0A2Y9HFA9   A0A182R1M1   A0A1L8EYS6   A0A3S1A630   R7V961   A0A2U3YT09   A0A1B0BLR1   W8BH80   A0A2K5QKU5   A0A1W5ABW9   A0A2Y9IEX0   F4WFX7   A9Z1C6   A0A3Q7PVV1   M3XLS6   A6QQM3   A0A2U3WA38   B7FEZ6   A0A2K6S285   G3QDZ8   A0A0L0CH63   Q5XI54   F6UPM5   A0A3Q7TJB2   A0A2Y9RA10   B7FEZ7   A0A2J8J374   A0A384BQ03   A0A3Q7Y663   A0A3M7T3F2   H0V1B6   B7FEZ8   B7FEZ4   A0A3Q1MEH8   A0A2K6EUJ2   V8PDV7   C3Z6W3   A0A1S3F7P7   Q95V50   G2HG10   B3DM08   A0A1S2ZXQ1   W5UCE8   W5NT62   Q9H069   A0A2J8RIA4   B3KSC6   A0A1W4WA79   A0A3P8ZP13   A0NG27   A0A2T7PVG3   H2NSX6  

PDB

6HKW     E-value=4.5536e-08,     Score=139

KEGG

101738722    no KO assigned | (RefSeq) leucine-rich repeat-containing protein 48

GO

GO:0005930   GO:0003824   GO:0031514   GO:0005737   GO:0005515   GO:0008152   GO:0008270   GO:0020037   GO:0006259   GO:0004813   GO:0006419   GO:0015923   GO:0005634   GO:0006260  

Subcellular location

Cytoplasm  
Cytoskeleton  
Cilium axoneme  
Cell projection  
Cilium  
Flagellum axoneme  

Length:

554

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00657999999999999

Exp number, first 60 AAs:

0.00533

Total prob of N-in:

0.00173

outside

1  -  554

 

 

Pi

205.403903

Theta

156.665657

Tajima's D

0.780122

CLR

0.351448

CSRT

0.588470576471176

Interpretation

Uncertain