SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO06475
Pre Gene Modal
BGIBMGA011861
Annotation
PREDICTED:_condensin_complex_subunit_2_[Amyelois_transitella]
Full name
Condensin complex subunit 2      
Alternative Name
Barren homolog protein 1
Chromosome-associated protein H
Non-SMC condensin I complex subunit H
XCAP-H homolog
Barren homolog
Chromosome assembly protein xCAP-H
Location in the cell
Nuclear   Reliability : 2.804
 

Sequence

CDS
ATGATGGAAAATCCTTTAACTTCAACGCCTGCCTTATCCAGGATTAGTATTGGCGGGAGCAGTAACACTTCAATTAGAAGACGTAGTTTGATACCTCAAAATAGAGTGGCCAATTCAAGAAATGAGGAGTGCAATGATGATGATGCTGAAAGGTCATCACTTGTGGCATCAGATCGCGTGGTTGCATCTACCCCACAGGCATCTCCACGTCGTGGAAGGGAGACTATGTCTTCATCACCACAGAAAGAACATTTCCAAGGTTGCCTTAAACTTTATGCAGAAAATAAAATAACAAAAGACAATGCATGGAATCTACAATTGATAGATTTTATGACTTCCATGCTTCGACGTCACGATGCTCGTATGGATAACTTGCAAACTGCTTCCACTGTGGTTGATGCTTCTGCTAGAATATACTCATTCAGAGTTGATGCCGTGCATTATGATGTACTTAAAATGGCTGGTGGTTTAATTAAAGCTGCTCAGTCAAAAAGAGGCAAAAAAGATGATGAAAATATACAAGACGAAGGTGCATTAGATGGAGATGTGAATGCTGCACCCATTAAGAAAAAAAAGAAACGATCTAAAGGAGCGATAGCAGCAAATCCAGAAGTTTTTAATGGTGATTTCGACATCAATGACTGTATAGATCCATTTTTTGAGAGGCTGGCCGCAACTACAGGAGATGTCACATCATCAAATAGAGCGTTCAATGCTACATTACCAATTCATGACAAAACTCTTGCGCTTATTCTGAGGACCGACACCAAGTTTTTAGAACCTGTCAAGGAGAACATCCCTGAAGAGTTGGACTTGTCACACCGCATCACCCTCGCCGTAAAGTTACTGCCGCCGTTTTTAGAAACGGATGCATTATGTGAGCCTTTCACGGGTTTCTCTATAAGCAATTGGGATCCGGATACCGAAGACAATGGGGAAAACAGAGTGACAAATTGGGTGGAAGAGAACAGATTGAATCTATCACAGCAAGCCTTGGCTTTTGATGTCAATGCTGAAGTGGAGCCGATACCTCAGGATGACTTACACAATGATTTGTATGACGATGAGCCGCTGGGAGGCGTGGAGAGCGGCGAGGAGGCGGACGCGGCCGTGGCGGCGTGCGTGGCGCGCGTGGCCCTCCCCGCGCCCCGCCTGGCCGACGCGCGCCCCTCCGCGCCGCACCACGCGCGCCTCGAGTACTCCTACTGCTCCCTGGCCGCCGCATGGGCGGGGCCCGCGCACTGGAGACTCAAAAACAACAGAGCATCAAAGCTTTCCGAGCGAACGCAATCGATGGGCGGGCGGCTGATGGCGGACGGCAACAAGAAGCCGGCGCGGACGAAGCGGCAGTTAGACTTCGAAGGCGCGGGACTCACGTTCGACTGCCGGTCCGCGCCCGTCGGGGACTACGAGCCCATCCAGCCGGCCAAGATCATGATCAGCAGGAAGACGCTCGCCACGGGACACACGTGGAACGAGACCAACTTTAAAACTCCTATTGATAGAGGTCTGGACGAATCGCACTTCTGCAAATTATTTTTACTGCGTAAAGTGACGATGTCGCGGAAACGTGACAACGAACACAGCAAGCCCGAGGAGCCCGTCACGGTCGAGGAGGTGCGCGACTACGATTACAATAATGAAAATGATGCCTCATATTGTCCCAACATACCGCCGGATGCTGACGAGTGGGGCAACGAGGACGCCACGGCCGCCGGCGACCTGCACGAACAAGTCAAAGCCGTAGAACTCGAAGACATCGGGGACATGCTCGAACCACCAACAAAAGTGGCCAAAATATTCATACCATACGCGATGCGGGCGAAAAAGGTCGACATGAAACAATTGAAAAACTGTACCTGGAAGATGCTCACTGAAAAAACTCCAGAAGGTTCCAAAGACGAGGTCACGGAAACGTCATTCTTTTCGATTTATTCCAGACTTCCGAGCAAACTGACGCCGAATATGAGAGAATCATTAAGTGTACCATTAGCTTTACTCTCAATTTTGCATTTAGCAAACGAAAAAGGATTGATTTTAGAGAAACAAGAAGACCTTAAGGACTTTGGCATAATAGGTTTGATAAAATAA
Protein
MMENPLTSTPALSRISIGGSSNTSIRRRSLIPQNRVANSRNEECNDDDAERSSLVASDRVVASTPQASPRRGRETMSSSPQKEHFQGCLKLYAENKITKDNAWNLQLIDFMTSMLRRHDARMDNLQTASTVVDASARIYSFRVDAVHYDVLKMAGGLIKAAQSKRGKKDDENIQDEGALDGDVNAAPIKKKKKRSKGAIAANPEVFNGDFDINDCIDPFFERLAATTGDVTSSNRAFNATLPIHDKTLALILRTDTKFLEPVKENIPEELDLSHRITLAVKLLPPFLETDALCEPFTGFSISNWDPDTEDNGENRVTNWVEENRLNLSQQALAFDVNAEVEPIPQDDLHNDLYDDEPLGGVESGEEADAAVAACVARVALPAPRLADARPSAPHHARLEYSYCSLAAAWAGPAHWRLKNNRASKLSERTQSMGGRLMADGNKKPARTKRQLDFEGAGLTFDCRSAPVGDYEPIQPAKIMISRKTLATGHTWNETNFKTPIDRGLDESHFCKLFLLRKVTMSRKRDNEHSKPEEPVTVEEVRDYDYNNENDASYCPNIPPDADEWGNEDATAAGDLHEQVKAVELEDIGDMLEPPTKVAKIFIPYAMRAKKVDMKQLKNCTWKMLTEKTPEGSKDEVTETSFFSIYSRLPSKLTPNMRESLSVPLALLSILHLANEKGLILEKQEDLKDFGIIGLIK

Summary

Description
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerase.
Subunit
Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG.
Component of the condensin complex, which contains the XCAP-E/SMC2 and XCAP-C/SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: XCAP-H/NCAPH, XCAP-D2/NCAPD2 and XCAP-G/NCAPG.
Similarity
Belongs to the CND2 (condensin subunit 2) family.
Keywords
Acetylation   Cell cycle   Cell division   Chromosome   Complete proteome   Cytoplasm   DNA condensation   Isopeptide bond   Mitosis   Nucleus   Phosphoprotein   Reference proteome   Ubl conjugation   Direct protein sequencing  
Feature
chain  Condensin complex subunit 2
EMBL
BABH01012286    NWSH01000980    PCG73269.1    KZ149967    PZC76153.1    ODYU01009339    + More
SOQ53694.1    KQ459590    KPI97222.1    KQ461161    KPJ08015.1    AGBW02003646    OWR55518.1    NEVH01027114    PNF13654.1    CH477367    EAT42499.1    ATLV01015900    KE525041    KFB40843.1    PYGN01000865    PSN39905.1    AXCN02001633    GANO01000109    JAB59762.1    KQ978069    KYM97351.1    UFQS01000056    UFQT01000056    SSW98758.1    SSX19144.1    DS232171    EDS36577.1    GL440609    EFN65704.1    LBMM01000327    KMR01212.1    KMR01216.1    AAAB01008956    EAL40154.3    GL888679    EGI58514.1    CVRI01000052    CRK99727.1    AXCM01002993    ADTU01027852    KQ976730    KYM76438.1    GL768112    EFZ12202.1    AAPE02045608    CM004471    OCT86627.1    BC068643    AAH68643.1    APCN01001921    JW865313    AFO97830.1    AK028919    AK042706    BC021499    BC025060    AAEX03010895    AABR07053670    CH473949    EDL80101.1    NNAY01001020    OXU25464.1    GEZM01051645    JAV74762.1    AAWZ02030918    AAWZ02030919    AQIA01016644    AQIA01016645    AQIA01016646    AQIA01016647    AQIA01016648    JU474929    AFH31733.1    AB179436    BAE02487.1    U90125    LSYS01002146    OPJ86907.1    AQIB01138625    CM001288    EHH55753.1    KB113832    ELK23220.1    ADFV01128028    ADFV01128029    ADFV01128030    AEMK02000020    DQIR01200155    HDB55632.1    AAGW02007418    AAMC01014037    AAMC01014038    AAMC01014039    JSUE03011503    JSUE03011504    JSUE03011505    CR848562    CAJ81260.1    BC080490    AAH80490.1    KB201362    ESO96826.1    ABGA01091508    ABGA01091509    ABGA01285652    ABGA01285653    ABGA01285654    ABGA01285655    NDHI03003755    PNJ03693.1    PNJ03697.1    AJFE02015193    AJFE02015194    AKHW03005679    KYO25678.1    AANG04003404   
Pfam
PF05786   Cnd2
Interpro
IPR022816   Condensin_barren_su2       

Ontologies

Topology

Subcellular location
Nucleus   In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase (By similarity).   With evidence from 2 publications.
Cytoplasm   In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase (By similarity).   With evidence from 2 publications.
Chromosome   In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase (By similarity).   With evidence from 2 publications.
Length:
696
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.00603
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00010
outside
1  -  696
 
 

Population Genetic Test Statistics

Pi
330.633886
Theta
196.303193
Tajima's D
2.066545
CLR
0.258884
CSRT
0.894255287235638
Interpretation
Uncertain
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