Gene

KWMTBOMO06473  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011862

Annotation

PREDICTED:_protein_arginine_N-methyltransferase_7_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr11(-):8591464-8598050      View in EpiBrowser

Full name

Protein arginine N-methyltransferase       + More
Protein arginine N-methyltransferase 7      

Location in the cell

Cytoplasmic   Reliability : 3.217

CDS

ATGAAGGTTTTCACGCAAAAAAGGAATCCTCTAACAGGCTGTACTGAGTGGGATATGCAAGATGAAGACAACGATTATCACCAAGAGATCGCCAGATCAGCCTTCGCTGATATGCTGCATGATACTGAGAGGAACCAAAAATATAGCAAGGCTTTGAAACTGGCTATTGAGAAAATGCACAATGATGGAAAGAAAGCCAATGTCTTGGATATTGGCACAGGTACAGGGCTCCTCTCCATAATGGCAGCAAAATCAGGTGCTGACACTATTGTTGCTTGTGAGGCTTTTCAACCTATGGCTGAATGCTGTCTCAGGATATTGGAATGCAATGGTGTGGCTGATAAGGTAACTGTTATCCCAAAAAGATCTACAGAACTGACTGTTGGTGAAAATGGAGATATGAAACAAAAAGCTAACATTCTAGTCACTGAAGTGTTTGATACAGAGTTAATTGGGGAAGGAGCTCTGTCAACATTCTCTCATGCGCACAAGTTCCTATTAGAAGAAGATGCTATAGTTGTGCCAGATTCAGCTGTCATATACGCTCAAGTTGTTGAATGTCCAATTTTGCAGAAATGGAATAAACTAAATGATCTAGCTGATGAAGATTTGCAAATTATTCTCAAGACTCCTAAAAAGATCAAGGAATGTGCTGGTTCGGCCGCTGTTCACGACGTGCAGCTGTCTCAAATATCGCGTCAATCATTCCGAGAGCTATCCGATCAGATACCGGTGTTCTACTATGATTGGTCGGGCGCTACTCCAATTATCATGCAGAGAACTGTGAAGCAAGAGTTCTCAGTGGTAACCACCGGTAAAGCGCAACTGGTGTTCATGTGGTGGGAGCTGAATATGGATCAAGAAGGAAAAATATCCTTGAGTTGCGCGCCGTGGTGGAGTCATCCAGATGCCGATATCTCGTCTCAGACGCCGCAGGACACAATTCCGTGGCGCGATCACTGGATGCAGGCGGTTTACTATCTACCGCAAGAAACTGAACTGCACAAAAGCATGGAGGCAACCCTGGTTTCGTGCCAGGACGAATACTCATTGTGGTTCTACGTGGAAACGGAACATAAACCACAACACTACCGGCGGCCGATCTGTGAATGTGGAGTTCACATGGCGTATTCGAGGACTCACGTCTCGTATTTGAACGACGGTAGGCGAAGCAAACAATTCTTGGCTCAACTGAAGAAGGAAATAACGAACGACTCGATTGTCCTGGATTTGAATGGAAGCAATTTCATGGGCTTGTCGGCCGCGAAAATGGGTGCCAAGGAGGTCTTCATTGTCGAAAAGATGAAAATGAATGTCGGCATTTTAATGGATTACATCGCCGAGAATAAGCTGAGCAACGTGACTGTTATACCGGAAGCCGGCGATGACGTTTTGAAGAAAGTGACCAATGTCGTAGGCGATCCTAGTTTCACCAGTGCCATATTGCCTTGGGAGAATTTGAAAATTGCCTATTTACTGTTTAAGTATAGGGAGAAATTGAACAGCGGTTTGTCGGTCATACCGGAGAGATGCGAGTTCTGGGCCGTGCCGGTGGAATTTCAGAATTTACACAAAATAAGGGTGCCGCTCGGCGTCTGCGAAGGGATTGATATGTCCAAATTCGACGAACTCGTCGAGACTTCTAGACTGATAAGCGACGCAGAAGTGGAAGCTCAGCCTCTGTGGGAGTACCCGAGTAAATGTCGCGGCGTACCGAGGAAGCTGATCGAAATTGATTTTCATGACCTGAAGCCTACTTACGCGTTTAATGGCGTACAACAAATAATAGAATCTCAAGACGATGAAGGTACTACATTAACTATAAATGGATTCGCGTTGTGGGCAGTGTGGAACATTGGTGGAAAGGACATAGTCACAGGTCCAATAAAGAGTCCTGTTTTAGGCGAAAATATCGAATGGGATCCTCACACAAGACAAGCGGTCAAAATACTTAAAAAGACTTTTACAATGAAGACTTCAGACAAATGGAGCTATCAAATCGCCTGCGACATTGAAAAAGGACAATTTAATGTCAATTTAGATTTAGTCTGTAATGAATAA

Protein

MKVFTQKRNPLTGCTEWDMQDEDNDYHQEIARSAFADMLHDTERNQKYSKALKLAIEKMHNDGKKANVLDIGTGTGLLSIMAAKSGADTIVACEAFQPMAECCLRILECNGVADKVTVIPKRSTELTVGENGDMKQKANILVTEVFDTELIGEGALSTFSHAHKFLLEEDAIVVPDSAVIYAQVVECPILQKWNKLNDLADEDLQIILKTPKKIKECAGSAAVHDVQLSQISRQSFRELSDQIPVFYYDWSGATPIIMQRTVKQEFSVVTTGKAQLVFMWWELNMDQEGKISLSCAPWWSHPDADISSQTPQDTIPWRDHWMQAVYYLPQETELHKSMEATLVSCQDEYSLWFYVETEHKPQHYRRPICECGVHMAYSRTHVSYLNDGRRSKQFLAQLKKEITNDSIVLDLNGSNFMGLSAAKMGAKEVFIVEKMKMNVGILMDYIAENKLSNVTVIPEAGDDVLKKVTNVVGDPSFTSAILPWENLKIAYLLFKYREKLNSGLSVIPERCEFWAVPVEFQNLHKIRVPLGVCEGIDMSKFDELVETSRLISDAEVEAQPLWEYPSKCRGVPRKLIEIDFHDLKPTYAFNGVQQIIESQDDEGTTLTINGFALWAVWNIGGKDIVTGPIKSPVLGENIEWDPHTRQAVKILKKTFTMKTSDKWSYQIACDIEKGQFNVNLDLVCNE

Description

Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
Essential arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins SmD1 and SmD3 (By similarity).
Essential arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins SmD1 and SmD3.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.

Keywords

Complete proteome   Methyltransferase   Reference proteome   Repeat   S-adenosyl-L-methionine   Transferase  

Feature

chain  Protein arginine N-methyltransferase 7

Uniprot

H9JQQ6   A0A2A4JMI7   A0A2A4JNH0   A0A2W1BTQ9   A0A3S2M909   A0A212FP37   + More
A0A194Q1E0   A0A0N1PFM0   A0A2H1WKU8   A0A0L7KVA1   U4UJN3   N6U7V8   D6WGQ7   A0A1W4WFH9   A0A067R8B3   A0A232FCC9   A0A154PJR7   K7IQS6   A0A2A3EJQ5   A0A1Y1KGQ9   A0A1Y1KH84   A0A026VRJ4   A0A087ZUC3   A0A0C9R667   A0A195CRI3   A0A310SBU5   A0A195DUS8   A0A158NQF5   A0A151JTD3   A0A0M9A7H8   A0A1B6I934   E9IDH1   A0A0L7R0Y7   A0A151HXV5   A0A1B6GMH2   A0A0J7L630   E2C297   W8B7T5   A0A1B6CG41   A0A1Q3F1I4   A0A2M4AJJ2   A0A2M4AJP0   A0A182RJK8   A0A182FEM5   A0A182LSP5   A0A182WWH9   A0A0L8IF92   A0A182I6Q9   A0A336L2X3   A0A182JRN5   A0A182TFM6   A0A182L3N5   Q7QIL2   A0A182UXJ6   A0A182Y2B4   A0A182SFN7   A0A182WBI1   W5JUH8   A0A1I8N5W2   Q16NS8   A0A1I8N5W1   A0A336M4I4   A0A1W4VDJ2   A0A2K7P6D1   A0A0J9RJJ5   A0A182PIJ4   B4QI55   B0X4N1   A0A2M4BG28   A0A2M4BG92   A0A182R0L6   B3NP10   A0A0L0CCY5   E2AK42   A0A0P5KIR5   A0A2M4BG17   A0A0P6B301   A0A0P5EFH1   A0A0P5KF27   A0A0N8BDN9   B4I8G2   Q9W1V1   A0A3L8DJ42   A0A210QHG6   B4P925   B3MF31   A0A1I8P928   R7T3H4   B4MNL1   A0A182JFC4   A0A084W139   A0A0P5D9B9   B4GA28   A0A0N8ENM5   B5DZN7   V4AM60   E9GEX5   A0A182N9B0  

EC Number

2.1.1.-

Pubmed

19121390    28756777    22118469    26354079    26227816    23537049    + More
18362917    19820115    24845553    28648823    20075255    28004739    24508170    21347285    21282665    20798317    24495485    20966253    12364791    25244985    20920257    23761445    25315136    17510324    22936249    17994087    12537575    26108605    10731132    12537572    12537569    14705965    18369183    30249741    28812685    23254933    24438588    15632085    21292972   

EMBL

BABH01012288    NWSH01000980    PCG73267.1    PCG73268.1    KZ149967    PZC76160.1    + More
RSAL01000010    RVE53723.1    AGBW02003646    OWR55511.1    KQ459590    KPI97215.1    KQ461161    KPJ08008.1    ODYU01009339    SOQ53701.1    JTDY01005370    KOB67070.1    KB632230    ERL90371.1    APGK01039285    KB740969    ENN76731.1    KQ971327    EEZ99615.1    KK852815    KDR15803.1    NNAY01000475    OXU28123.1    KQ434938    KZC12131.1    KZ288223    PBC31995.1    GEZM01087317    JAV58775.1    GEZM01087316    JAV58776.1    KK111577    EZA46347.1    GBYB01008277    JAG78044.1    KQ977444    KYN02719.1    KQ761738    OAD57130.1    KQ980322    KYN16628.1    ADTU01023205    ADTU01023206    ADTU01023207    ADTU01023208    ADTU01023209    KQ981998    KYN30716.1    KQ435732    KOX77449.1    GECU01024287    JAS83419.1    GL762454    EFZ21437.1    KQ414669    KOC64514.1    KQ976734    KYM76149.1    GECZ01006134    JAS63635.1    LBMM01000407    KMQ98432.1    GL452091    EFN77934.1    GAMC01011898    JAB94657.1    GEDC01025406    GEDC01024917    GEDC01012169    JAS11892.1    JAS12381.1    JAS25129.1    GFDL01013625    JAV21420.1    GGFK01007625    MBW40946.1    GGFK01007682    MBW41003.1    AXCM01009146    KQ415846    KOG00151.1    APCN01003693    UFQS01001426    UFQT01001426    SSX10829.1    SSX30509.1    AAAB01008807    ADMH02000413    ETN66620.1    CH477810    UFQT01000550    SSX25176.1    CM002911    KMY95957.1    CM000362    DS232348    GGFJ01002853    MBW51994.1    GGFJ01002852    MBW51993.1    AXCN02000558    AY190941    CH954179    JRES01000577    KNC30072.1    GL440171    EFN66197.1    GDIQ01190600    JAK61125.1    GGFJ01002854    MBW51995.1    GDIP01022013    JAM81702.1    GDIP01160938    GDIP01145646    LRGB01002121    JAJ62464.1    KZS09051.1    GDIQ01186296    JAK65429.1    GDIQ01187947    JAK63778.1    CH480824    AE013599    AY113590    BT046131    QOIP01000008    RLU19949.1    NEDP02003738    OWF48041.1    CM000158    CH902619    AMQN01003638    KB312379    ELT87312.1    CH963848    ATLV01019208    KE525264    KFB43933.1    GDIP01159343    JAJ64059.1    CH479181    GDIQ01009068    JAN85669.1    CM000071    KB201262    ESO98227.1    GL732541    EFX82005.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000007151    UP000053268    UP000053240    + More
UP000037510    UP000030742    UP000019118    UP000007266    UP000192223    UP000027135    UP000215335    UP000076502    UP000002358    UP000242457    UP000053097    UP000005203    UP000078542    UP000078492    UP000005205    UP000078541    UP000053105    UP000053825    UP000078540    UP000036403    UP000008237    UP000075900    UP000069272    UP000075883    UP000076407    UP000053454    UP000075840    UP000075881    UP000075902    UP000075882    UP000007062    UP000075903    UP000076408    UP000075901    UP000075920    UP000000673    UP000095301    UP000008820    UP000192221    UP000075885    UP000000304    UP000002320    UP000075886    UP000008711    UP000037069    UP000000311    UP000076858    UP000001292    UP000000803    UP000279307    UP000242188    UP000002282    UP000007801    UP000095300    UP000014760    UP000007798    UP000075880    UP000030765    UP000008744    UP000001819    UP000030746    UP000000305    UP000075884   

PRIDE

H9JQQ6    Q16NS8    Q9W1V1   

Pfam

PF00270   DEAD        + More
PF00271   Helicase_C
PF00179   UQ_con
PF02475   Met_10

Interpro

IPR014644   MeTrfase_PRMT7        + More
IPR029063   SAM-dependent_MTases       
IPR025799   Arg_MeTrfase       
IPR027417   P-loop_NTPase       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR014014   RNA_helicase_DEAD_Q_motif       
IPR000629   RNA-helicase_DEAD-box_CS       
IPR014001   Helicase_ATP-bd       
IPR001650   Helicase_C       
IPR000608   UBQ-conjugat_E2       
IPR016135   UBQ-conjugating_enzyme/RWD       
IPR030382   MeTrfase_TRM5/TYW2       

SUPFAM

SSF53335   SSF53335        + More
SSF52540   SSF52540       
SSF54495   SSF54495       

Gene 3D

3.10.110.10    

CDD

cd00079  HELICc

ProteinModelPortal

H9JQQ6   A0A2A4JMI7   A0A2A4JNH0   A0A2W1BTQ9   A0A3S2M909   A0A212FP37   + More
A0A194Q1E0   A0A0N1PFM0   A0A2H1WKU8   A0A0L7KVA1   U4UJN3   N6U7V8   D6WGQ7   A0A1W4WFH9   A0A067R8B3   A0A232FCC9   A0A154PJR7   K7IQS6   A0A2A3EJQ5   A0A1Y1KGQ9   A0A1Y1KH84   A0A026VRJ4   A0A087ZUC3   A0A0C9R667   A0A195CRI3   A0A310SBU5   A0A195DUS8   A0A158NQF5   A0A151JTD3   A0A0M9A7H8   A0A1B6I934   E9IDH1   A0A0L7R0Y7   A0A151HXV5   A0A1B6GMH2   A0A0J7L630   E2C297   W8B7T5   A0A1B6CG41   A0A1Q3F1I4   A0A2M4AJJ2   A0A2M4AJP0   A0A182RJK8   A0A182FEM5   A0A182LSP5   A0A182WWH9   A0A0L8IF92   A0A182I6Q9   A0A336L2X3   A0A182JRN5   A0A182TFM6   A0A182L3N5   Q7QIL2   A0A182UXJ6   A0A182Y2B4   A0A182SFN7   A0A182WBI1   W5JUH8   A0A1I8N5W2   Q16NS8   A0A1I8N5W1   A0A336M4I4   A0A1W4VDJ2   A0A2K7P6D1   A0A0J9RJJ5   A0A182PIJ4   B4QI55   B0X4N1   A0A2M4BG28   A0A2M4BG92   A0A182R0L6   B3NP10   A0A0L0CCY5   E2AK42   A0A0P5KIR5   A0A2M4BG17   A0A0P6B301   A0A0P5EFH1   A0A0P5KF27   A0A0N8BDN9   B4I8G2   Q9W1V1   A0A3L8DJ42   A0A210QHG6   B4P925   B3MF31   A0A1I8P928   R7T3H4   B4MNL1   A0A182JFC4   A0A084W139   A0A0P5D9B9   B4GA28   A0A0N8ENM5   B5DZN7   V4AM60   E9GEX5   A0A182N9B0  

PDB

6OGN     E-value=8.80368e-129,     Score=1181

KEGG

101742905    K11438 type III protein arginine methyltransferase [EC:2.1.1.321] | (RefSeq) protein arginine N-meth

GO

GO:0008168   GO:0006479   GO:0016021   GO:0008469   GO:0035241   GO:0006355   GO:0035242   GO:0034969   GO:0005829   GO:0005524   GO:0003676   GO:0035243   GO:0018216   GO:0016274   GO:0019919   GO:0006265   GO:0006259   GO:0004813   GO:0006419   GO:0015923   GO:0005634   GO:0006260  

Length:

686

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.12399

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00660

outside

1  -  686

 

 

Pi

192.377279

Theta

154.598433

Tajima's D

0.860098

CLR

0

CSRT

0.621618919054047

Interpretation

Uncertain