Gene

KWMTBOMO06470

Pre Gene Modal

BGIBMGA011864

Annotation

PREDICTED:_lipase_member_H-A-like_[Bombyx_mori]

Location

Bomo_Chr11(-):7979146-7981550      View in EpiBrowser

Full name

Lipase member H-A       + More
Lipase member H-B      
Lipase member H      

Location in the cell

PlasmaMembrane   Reliability : 2.995

CDS

ATGAAAGAGTTGGCAAGGGATCCTAATGTTAATTTTATGAAGAAAACGCTACTGTACTTCCCAGGTTATCTTGACAGTCCATCATTTATATTCTCACCAGTAATAGCGTCGGCTTATACTAAACGCGGTTACAATGTATTATCAGTGGACATACATTGGTTCGTGACCACTGAATATCCAATCGCATCTCGCCTTAGTCGTGCCCTGGGGCCGCATATAGCTTCAATGGTGGTTGAACTCATGAAGGAAGGACTCGACATAAACAAATTGGATCTCGTCGGGATCAGCTTAGGAGCTCAAGTCATGAGCTTCGCCGCGAAAAGCTTCACAAACATGACGGGAACCAAATTTAAAAGAGCCACGGGCCTTGATCCTACAGGGGTCTGCTTTAGGAACCTCGGCCCTGAGGACAGACTGGACTCGTCGGACGTAGAGTTCCTAGACGTGGTGTACACTAATATAGATGGTTACGGTATGGCTGCGCCCATTGGACACATCAATTTCTATGTCAACGGCGGAGAGTACCAACAAAGCATACTAATACCCATATTGTGCACATTTTTATGCAGTCACATCAGATCCTTTCTGTTATGGGTGACAGCGATTTATCATCCAAAATCGTTTATAGGAATTCAGTGCGATTCGGTATACGATGCCAGAATAGGGAATTGCTTTGACGGTGGTCCGAGAGAGACGAACGTACTAGGATTGAAAGTTGATAAAACTAAGCAAGGTATATTTTATTTGGCCACAAAGAACACGTTCCCGTATTATTTAGAGGAAAAGGGTTTGGTGAAAGGAAGCGACTCGTTGTCGCAGTATTTCTTAGATGTCAACAAGGAAGATGTGTTAAGGTTTAAATAA

Protein

MKELARDPNVNFMKKTLLYFPGYLDSPSFIFSPVIASAYTKRGYNVLSVDIHWFVTTEYPIASRLSRALGPHIASMVVELMKEGLDINKLDLVGISLGAQVMSFAAKSFTNMTGTKFKRATGLDPTGVCFRNLGPEDRLDSSDVEFLDVVYTNIDGYGMAAPIGHINFYVNGGEYQQSILIPILCTFLCSHIRSFLLWVTAIYHPKSFIGIQCDSVYDARIGNCFDGGPRETNVLGLKVDKTKQGIFYLATKNTFPYYLEEKGLVKGSDSLSQYFLDVNKEDVLRFK

Description

Hydrolyzes specifically phosphatidic acid (PA) to produce lysophosphatidic acid (LPA).

Similarity

Belongs to the AB hydrolase superfamily. Lipase family.

Keywords

Disulfide bond   Glycoprotein   Hydrolase   Lipid degradation   Lipid metabolism   Membrane   Secreted   Signal   Complete proteome   Reference proteome  

Feature

chain  Lipase member H-A

Uniprot

H9JQQ8   A0A194Q1D6   A0A212FBR8   H9JQ12   A0A0N1II42   A0A2H1WK50   + More
A0A2W1B572   A0A2W1BNT7   A0A2H1WL24   H9JHY8   A0A0L7LHY6   A0A194QUH6   A0A3S2LBT4   A0A194QBX2   A0A194QBZ0   A0A212FPW6   A0A0N1IGL3   A0A2H1VJ13   A0A2A4JBH9   A0A191XQW7   A0A3S2P6E3   A0A0L7L1G4   A0A3S2PK48   A0A2W1BL36   A0A2A4JXD4   A0A212EY15   A0A194QZ66   A0A2H1VGU5   A0A194PEP3   H9JXD2   H9IUE6   A0A3S2NZZ7   A0A2H1W795   A0A2W1BWG2   A0A2H1W7F1   A0A212EJL3   A0A2H1W7Q1   A0A0L7L8R4   A0A2W1BXY3   A0A0N1PJG6   A0A2W1BV63   A0A2H1WNR8   A0A2A4J5Z0   D6WBV6   A0A2H1WL84   A0A0L7KP71   A0A2A4IT83   A0A3S2L3L9   H9JWY8   A0A220K8L9   A0A2A4JGD9   A0A194RQL7   A0A2H1X3Q9   I6TFN4   A0A0A1WYA6   A0A194Q121   A0A158NYL0   A0A2A4JYV7   A0A194PSE8   Q6PA23   A0A1L8HCT6   E9JDF3   S4RQL2   A0A212FKA5   A0A194QNS4   F4WY21   E9JDE9   A0A1L8H505   K7IZY1   A0A194PCA8   A0A2Y9MW57   A0A2W1B7Q2   A0A2Y9MW48   Q641F6   A0A3Q7T0N8   A0A194QC74   A0A2A4J1M9   F7BXT5   F7C8U5   A0A026X3P3   A0A337S3D4   D2H293   A0A3Q7VVY4   A0A1I8MA26   L5JRL1   A0A195AZA7   Q5XGE9   G1MEH3   A0A0L0CRF9   W8CB58   E2A4Y7   A0A2K5RJH5   F1PG57  

EC Number

3.1.1.-

Pubmed

19121390    26354079    22118469    28756777    26227816    18362917    + More
19820115    28630352    23171126    25830018    21347285    27762356    21282665    21719571    20075255    20431018    24508170    30249741    17975172    20010809    25315136    23258410    26108605    24495485    20798317    16341006   

EMBL

BABH01012334    KQ459590    KPI97210.1    AGBW02009288    OWR51181.1    KQ460391    + More
KPJ15413.1    ODYU01009136    SOQ53346.1    KZ150534    PZC70591.1    KZ149947    PZC76719.1    ODYU01009344    SOQ53707.1    BABH01035306    JTDY01001036    KOB75067.1    KQ461154    KPJ08630.1    RSAL01000052    RVE50204.1    KQ459193    KPJ03053.1    KPJ03068.1    AGBW02000859    OWR55743.1    KQ460781    KPJ12226.1    ODYU01002823    SOQ40786.1    NWSH01002209    PCG68904.1    KU360126    ANJ42864.1    RSAL01000291    RVE42897.1    JTDY01003560    KOB69343.1    RSAL01000010    RVE53725.1    KZ149983    PZC75749.1    NWSH01000400    PCG76675.1    AGBW02011630    OWR46389.1    KQ460947    KPJ10569.1    ODYU01002500    SOQ40069.1    KQ459606    KPI91164.1    BABH01035864    BABH01001181    RSAL01000012    RVE53468.1    ODYU01006796    SOQ48975.1    KZ149926    PZC77547.1    SOQ48977.1    AGBW02014435    OWR41693.1    SOQ48976.1    JTDY01002277    KOB71750.1    PZC77546.1    KQ460240    KPJ16392.1    PZC77545.1    ODYU01009953    SOQ54715.1    NWSH01003103    PCG66944.1    KQ971315    EEZ97864.2    ODYU01009427    SOQ53845.1    JTDY01007594    KOB65092.1    NWSH01007523    PCG62931.1    RSAL01000184    RVE44850.1    BABH01041781    MF319718    ASJ26432.1    NWSH01001670    PCG70462.1    KQ459833    KPJ19782.1    ODYU01013233    SOQ59929.1    JQ814807    AFM73623.1    GBXI01010636    JAD03656.1    KQ459580    KPI99251.1    ADTU01004020    NWSH01000413    PCG76562.1    KQ459601    KPI94050.1    BC060482    CM004468    OCT93917.1    GL771866    EFZ09320.1    AGBW02008082    OWR54177.1    KQ461196    KPJ06625.1    GL888434    EGI60946.1    EFZ09198.1    CM004469    OCT91179.1    KPI90911.1    KZ150304    PZC71518.1    BC082381    KPJ03024.1    NWSH01003717    PCG65891.1    AAMC01004521    AAMC01004522    KK107013    QOIP01000003    EZA62897.1    RLU25094.1    AANG04001816    GL192440    EFB29618.1    KB031155    ELK00778.1    KQ976701    KYM77372.1    BC084493    ACTA01050209    ACTA01058209    JRES01000120    KNC34019.1    GAMC01000754    JAC05802.1    GL436770    EFN71504.1    AAEX03017289   

Proteomes

UP000005204    UP000053268    UP000007151    UP000053240    UP000037510    UP000283053    + More
UP000218220    UP000007266    UP000005205    UP000186698    UP000245300    UP000007755    UP000002358    UP000248483    UP000286640    UP000008143    UP000053097    UP000279307    UP000011712    UP000286642    UP000095301    UP000010552    UP000078540    UP000008912    UP000037069    UP000000311    UP000233040    UP000002254   

PRIDE

H9JQQ8    H9JQ12    H9JHY8    H9JXD2    H9IUE6    H9JWY8    + More
Q6PA23    Q641F6   

Pfam

PF00151   Lipase

Interpro

IPR029058   AB_hydrolase        + More
IPR013818   Lipase/vitellogenin       
IPR000734   TAG_lipase       
IPR033906   Lipase_N       
IPR002334   Allerg_PlipaseA1       
IPR016272   Lipase_LIPH       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

CDD

cd00707  Pancreat_lipase_like

ProteinModelPortal

H9JQQ8   A0A194Q1D6   A0A212FBR8   H9JQ12   A0A0N1II42   A0A2H1WK50   + More
A0A2W1B572   A0A2W1BNT7   A0A2H1WL24   H9JHY8   A0A0L7LHY6   A0A194QUH6   A0A3S2LBT4   A0A194QBX2   A0A194QBZ0   A0A212FPW6   A0A0N1IGL3   A0A2H1VJ13   A0A2A4JBH9   A0A191XQW7   A0A3S2P6E3   A0A0L7L1G4   A0A3S2PK48   A0A2W1BL36   A0A2A4JXD4   A0A212EY15   A0A194QZ66   A0A2H1VGU5   A0A194PEP3   H9JXD2   H9IUE6   A0A3S2NZZ7   A0A2H1W795   A0A2W1BWG2   A0A2H1W7F1   A0A212EJL3   A0A2H1W7Q1   A0A0L7L8R4   A0A2W1BXY3   A0A0N1PJG6   A0A2W1BV63   A0A2H1WNR8   A0A2A4J5Z0   D6WBV6   A0A2H1WL84   A0A0L7KP71   A0A2A4IT83   A0A3S2L3L9   H9JWY8   A0A220K8L9   A0A2A4JGD9   A0A194RQL7   A0A2H1X3Q9   I6TFN4   A0A0A1WYA6   A0A194Q121   A0A158NYL0   A0A2A4JYV7   A0A194PSE8   Q6PA23   A0A1L8HCT6   E9JDF3   S4RQL2   A0A212FKA5   A0A194QNS4   F4WY21   E9JDE9   A0A1L8H505   K7IZY1   A0A194PCA8   A0A2Y9MW57   A0A2W1B7Q2   A0A2Y9MW48   Q641F6   A0A3Q7T0N8   A0A194QC74   A0A2A4J1M9   F7BXT5   F7C8U5   A0A026X3P3   A0A337S3D4   D2H293   A0A3Q7VVY4   A0A1I8MA26   L5JRL1   A0A195AZA7   Q5XGE9   G1MEH3   A0A0L0CRF9   W8CB58   E2A4Y7   A0A2K5RJH5   F1PG57  

PDB

1BU8     E-value=3.79663e-22,     Score=257

KEGG

101742752    K19404 phosphatidic acid-selective phospholipase A1 [EC:3.1.1.-] | (RefSeq) lipase member H-A-like

GO

GO:0005576   GO:0052689   GO:0016021   GO:0006629   GO:0016042   GO:0016298   GO:0005615   GO:0008970   GO:0016020   GO:0046872   GO:0004620   GO:0008201   GO:0005886  

PANTHER

PTHR11610  

Subcellular location

Secreted  
Membrane  

Length:

287

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

15.87402

Exp number, first 60 AAs:

8.95825

Total prob of N-in:

0.43125

outside

1  -  287

 

 

Pi

192.122272

Theta

143.638121

Tajima's D

1.000019

CLR

0.041759

CSRT

0.665166741662917

Interpretation

Uncertain