Gene

KWMTBOMO06460

Pre Gene Modal

BGIBMGA011614

Annotation

PREDICTED:_uncharacterized_protein_LOC101743046_[Bombyx_mori]

Location

Bomo_Chr11(+):7716471-7799578      View in EpiBrowser

Full name

RBR-type E3 ubiquitin transferase      

Location in the cell

Extracellular   Reliability : 2.618

CDS

ATGGGAGCAGGCGCGAACGGGCCTGGTGGCCGTCGAGCCCTCGAGCTCATCCTCAGCGGGGGGCTGAAGTCTCTAGGGCGTCCAGCAAAGCCCGTGCGCAGGGCTGCGTCCCGTGACTCCGTGCTGTCACAACCGCAGCCCCTGCTTGAAGGCTTGAGGAAATGTTCGACAGTCCTCGCACTGACGGACCGGGAGAAGGTTCCCGAACCGATTAGGGCTCACAACCGACTCCGCGCGCCCTCCGTCTGCTCTCGCTGCTCCTCTCTGCTGTCGCTCGCCGGCGCTGGTGGTTCCAGGTATTCCCTGGACGGTGCCGGCGGTGGCTTCGTTGCAGCCGCTCCGATCAACTGCAAGCTGTGCCTTGAAGACGCGACCGCTGACAAGGTCACTATTATAGGCGGCTGTGGTTGCACATTCTGCACTAAGTGTATGAAAGCATACGTCGAATTCGAAGTCTGCAACGGCGCGTATGAGGTTTCATGCCCTGACGCGAGGTGCAGGCTGGGCGCCGCCCTCGCCTTGGACGAGATCTCCGCTCTCGTTGAACCCGCTGTTATGGAGAAGCATCTCAAATTCAGGCTCAATCATGAAGTGGCGATGGACTCCGGTCGAGCGTTCTGTCCCCGCGTCGGATGCGACACGGTGGTGTCCGTCCGGGCCGCCAGTCCCGCACATTGTCCGACGTGCCGGCACGATTTCTGCTCCCAGTGCAACCAGGAGTGGCACGGCGGGATGACTTGCGAGGCGGCGGCGGCCTCGTCTTCGATGGGCGGCGCCGGGGCCCCATTGCTACCGGACTCCGAGCTGATCAAGCTCTGCCCGATGTGCAGGGTGCCAATAGAGAAGGACGAGGGATGCGCCCAGATGATGTGTAAACGATGCAAGCACGTATTCTGCTGGTACTGCCTCGCTTCCCTCGATGACGATTTCCTTCTACGACACTACGACAAGGGACCGTGCAAAAACAAACTTGGACACTCGCGAGCTTCTGTACTGTGGCACCGTGCTCAAGTTGTCGGTATATTTGCTGGCTTCGGTTTGCTGCTGTTGGTCGCCAGTCCGCTGTTGCTGCTCGCGGCCCCCTGTATCGTGTGCTGCAAGTGCAGGCTGTGCAATCCAAGCACGAAGAATCTTGAAGAGGTAGACGAGGTCGATAGCATCAGTCCCGGGAGGGACGACGATGACGAGATCACCCACGAGAGGTCCCGGGATCGATATCTGAGCGACTGA

Protein

MGAGANGPGGRRALELILSGGLKSLGRPAKPVRRAASRDSVLSQPQPLLEGLRKCSTVLALTDREKVPEPIRAHNRLRAPSVCSRCSSLLSLAGAGGSRYSLDGAGGGFVAAAPINCKLCLEDATADKVTIIGGCGCTFCTKCMKAYVEFEVCNGAYEVSCPDARCRLGAALALDEISALVEPAVMEKHLKFRLNHEVAMDSGRAFCPRVGCDTVVSVRAASPAHCPTCRHDFCSQCNQEWHGGMTCEAAAASSSMGGAGAPLLPDSELIKLCPMCRVPIEKDEGCAQMMCKRCKHVFCWYCLASLDDDFLLRHYDKGPCKNKLGHSRASVLWHRAQVVGIFAGFGLLLLVASPLLLLAAPCIVCCKCRLCNPSTKNLEEVDEVDSISPGRDDDDEITHERSRDRYLSD

Catalytic Activity

[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.

Similarity

Belongs to the RBR family.

Uniprot

A0A2A4KBD4   A0A3S2LH58   A0A1Y1MDK5   A0A026VUJ3   A0A0M9A630   E2BKP4   + More
A0A158NTE1   A0A151X1R0   A0A195B3V1   E2APP3   F4W3Z3   A0A195DVY5   A0A195ETI7   A0A088AAJ4   A0A2A3E2X4   U4UCR9   A0A195CKP2   A0A0T6AWF7   E9I9R3   V5GUD2   A0A0C9PJ48   D6WF51   A0A1W4WMH4   A0A1B6FMK2   A0A1W4WLC4   A0A1B6IE33   A0A0L7RHS9   A0A1W4WB63   A0A067R8D2   A0A1B6CD37   A0A1B6M7G2   A0A1L8DSM8   A0A1L8DT43   A0A2R7X958   K7IXP0   Q16LE5   A0A1B0CJH7   A0A2M4BEG9   A0A2M4BEA9   A0A2M4BED8   A0A023F4Z4   A0A2M4CHZ5   A0A2M4A3G4   A0A2M4A2U2   A0A2M4A363   A0A2M4CGG2   A0A2M4CGW4   A0A2M4BA12   A0A2M4BAR6   A0A2M4BAF7   A0A182Q0S4   J9JSU1   A0A2S2RAK7   A0A2S2P8K4   A0A2H8TYN4   B4MNX8   A0A1Y1MAJ4   A0A1Y1MA31   W5JF28  

EC Number

2.3.2.31

Pubmed

28004739    24508170    30249741    20798317    21347285    21719571    + More
23537049    21282665    18362917    19820115    24845553    20075255    17510324    25474469    17994087    20920257    23761445   

EMBL

NWSH01000006    PCG80982.1    RSAL01000010    RVE53731.1    GEZM01036460    GEZM01036459    + More
JAV82680.1    KK107847    QOIP01000005    EZA47468.1    RLU22549.1    KQ435727    KOX77985.1    GL448819    EFN83742.1    ADTU01025859    KQ982585    KYQ54225.1    KQ976625    KYM78947.1    GL441572    EFN64594.1    GL887491    EGI70989.1    KQ980295    KYN16902.1    KQ981979    KYN31553.1    KZ288444    PBC25662.1    KB631992    ERL87755.1    KQ977642    KYN01022.1    LJIG01022685    KRT79259.1    GL761846    EFZ22711.1    GALX01004613    JAB63853.1    GBYB01000988    JAG70755.1    KQ971327    EEZ99843.2    GECZ01026480    GECZ01018334    GECZ01017266    GECZ01005173    JAS43289.1    JAS51435.1    JAS52503.1    JAS64596.1    GECU01022544    JAS85162.1    KQ414585    KOC70542.1    KK852815    KDR15823.1    GEDC01025987    JAS11311.1    GEBQ01008136    JAT31841.1    GFDF01004598    JAV09486.1    GFDF01004599    JAV09485.1    KK857711    PTY27425.1    AAZX01008686    CH477909    EAT35140.1    AJWK01014647    AJWK01014648    AJWK01014649    AJWK01014650    AJWK01014651    AJWK01014652    AJWK01014653    AJWK01014654    AJWK01014655    AJWK01014656    GGFJ01002252    MBW51393.1    GGFJ01002233    MBW51374.1    GGFJ01002222    MBW51363.1    GBBI01002599    JAC16113.1    GGFL01000360    MBW64538.1    GGFK01001857    MBW35178.1    GGFK01001805    MBW35126.1    GGFK01001933    MBW35254.1    GGFL01000226    MBW64404.1    GGFL01000223    MBW64401.1    GGFJ01000754    MBW49895.1    GGFJ01000767    MBW49908.1    GGFJ01000875    MBW50016.1    AXCN02001004    ABLF02026350    ABLF02026354    GGMS01017810    MBY87013.1    GGMR01013162    MBY25781.1    GFXV01007096    MBW18901.1    CH963848    EDW73817.2    GEZM01036457    JAV82683.1    GEZM01036458    JAV82682.1    ADMH02001334    ETN62972.1   

Proteomes

UP000218220    UP000283053    UP000053097    UP000279307    UP000053105    UP000008237    + More
UP000005205    UP000075809    UP000078540    UP000000311    UP000007755    UP000078492    UP000078541    UP000005203    UP000242457    UP000030742    UP000078542    UP000007266    UP000192223    UP000053825    UP000027135    UP000002358    UP000008820    UP000092461    UP000075886    UP000007819    UP000007798    UP000000673   

Pfam

PF01485   IBR

Interpro

IPR002867   IBR_dom        + More
IPR031127   E3_UB_ligase_RBR       
IPR001841   Znf_RING       
IPR017907   Znf_RING_CS       
IPR013083   Znf_RING/FYVE/PHD       

Gene 3D

3.30.40.10    

ProteinModelPortal

A0A2A4KBD4   A0A3S2LH58   A0A1Y1MDK5   A0A026VUJ3   A0A0M9A630   E2BKP4   + More
A0A158NTE1   A0A151X1R0   A0A195B3V1   E2APP3   F4W3Z3   A0A195DVY5   A0A195ETI7   A0A088AAJ4   A0A2A3E2X4   U4UCR9   A0A195CKP2   A0A0T6AWF7   E9I9R3   V5GUD2   A0A0C9PJ48   D6WF51   A0A1W4WMH4   A0A1B6FMK2   A0A1W4WLC4   A0A1B6IE33   A0A0L7RHS9   A0A1W4WB63   A0A067R8D2   A0A1B6CD37   A0A1B6M7G2   A0A1L8DSM8   A0A1L8DT43   A0A2R7X958   K7IXP0   Q16LE5   A0A1B0CJH7   A0A2M4BEG9   A0A2M4BEA9   A0A2M4BED8   A0A023F4Z4   A0A2M4CHZ5   A0A2M4A3G4   A0A2M4A2U2   A0A2M4A363   A0A2M4CGG2   A0A2M4CGW4   A0A2M4BA12   A0A2M4BAR6   A0A2M4BAF7   A0A182Q0S4   J9JSU1   A0A2S2RAK7   A0A2S2P8K4   A0A2H8TYN4   B4MNX8   A0A1Y1MAJ4   A0A1Y1MA31   W5JF28  

PDB

4KC9     E-value=8.13932e-12,     Score=170

KEGG

101743046    K11975 E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31] | (RefSeq) uncharacterized LOC101743046

GO

GO:0016021   GO:0004842   GO:0046872   GO:0016740   GO:0016874   GO:0000209   GO:0005737   GO:0006511   GO:0032436   GO:0000151   GO:0031624   GO:0061630   GO:0005515   GO:0008270   GO:0005388   GO:0006816   GO:0004813   GO:0006419   GO:0015923   GO:0005634   GO:0006260  

PANTHER

PTHR11685  

Length:

409

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.72039

Exp number, first 60 AAs:

0.00036

Total prob of N-in:

0.01143

outside

1  -  337

TMhelix

338  -  360

inside

361  -  409

 

 

Pi

223.634098

Theta

171.101977

Tajima's D

0.711152

CLR

0.518674

CSRT

0.575471226438678

Interpretation

Uncertain