Gene

KWMTBOMO06453  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011872

Annotation

PREDICTED:_calcium-transporting_ATPase_type_2C_member_1_isoform_X2_[Amyelois_transitella]

Location

Bomo_Chr11(-):7391528-7432970      View in EpiBrowser

Full name

Calcium-transporting ATPase      

Location in the cell

PlasmaMembrane   Reliability : 3.907

CDS

ATGTGGATCAGCGCAGTCGAGAGCTCTATACTGACATGGGAGGAGGTATCGGAGCGTTTGAGCGTCGACGTCCGCCGAGGCTTGTCATGGCGCGAAGCCAACGACCGCATGAACTTCGTTGGAGCCAACGAGTTTCAGGTGAAGGAACAAGATCCGCTCTGGAAGAAGTACATCGAGCAGTTCCAGAATCCGCTCATACTCCTGCTTCTCGGATCGGCGGTGGTGAGCGTTTGCATGCGCCAGTTCGACGACGCGATATCTATCACGGTCGCCATCATCATCGTGGTGACCGTCGCCTTCGTCCAGGAGTACCGCTCGGAGAAGTCGCTCGAGGAACTCAATAAACTTGTGCCTCCGTCATGCAATTGCCTTCGAGAGGGAAGTCTCGAGCACTTCCTCGCCCGCAACCTGGTCCCAGGCGACATCGTCCACCTGAACGTCGGGGACAGGGTGCCGGCCGACCTGCGGCTCTTCGACTCCACGGACCTGGCCATCGACGAGTCATCGTTCACCGGGGAAACAGAACCCGCCGTCAAGAACATCGTGCCAAACAAAGCGGCCGCCGGCAGGGTCAACAAGGATAACATAGCCTTCATGGGAACACTGGTTAGATGCGGAAATGCTAAGGGCATTGTGGTCAGCACGGGAGAACGTTCAGAGTTCGGTGACATTTTCCGCATGATGCAAGCCGAAGAAGCCCCGAAGACCCCGCTCCAGAAGTCCATGGATACCCTCGGGGGCCAGCTCTCGATGTACTCCTTCTGCATCATCGGCTTTATCATGATCACGGGGTGGCTCCAAGGAAAAGCCCTGCAGGAGATGTTCACTATCGGCGTCAGTCTCGCCGTTGCTGCCATACCCGAAGGTCTGCCAATAGTCGTGACTGTGACCCTGGCCCTCGGAGTCATGAGAATGGCGAAACGTAACGCCATAGTGAAGAAGCTGCCCACCGTTGAGACTTTGGGATGCGTTAATGTCATCTGCAGTGACAAGACGGGAACGTTGACGAAGAATGAAATGACAGTGACGACAATAGCGACATCCGGCGGCCACATCGCCGAAGTGACCGGAACGGGATACAACGGGCGCGGCGACATACAACTGCGAGCCTACAAGGGCAGAGATCTGGACGTGGCCAGGATGGGTGTCACCAGCATGTTGGAGGTGGCGGTACTGTGCAACAACGCGCACATCCGCGATGAGACGCTGTACGGGCAGCCCACGGAGGGCGCGCTCGTCGCCTGCGCCATGAAGCACGGCCTACGCGACCTCCGGGAACAGTACACCAGGCTGCACGAGATACCCTTCAGCTCAGAAACGAAGATGATGGTCGTGAAATGCGCCCCGAAGTTCTCCGACGGCGGCAAAGAGGAGTTGTTCGTGAAGGGGGCCGTCGAGAAGGTCCTGCCGCTGTGCACGCAGTACATCGACAGCGCCGGCAACTACGCGCCGCTCACGAACGAGAAGCAGAACGAAATATTAGCCGAGGTGTACAACATCGGACGAATGGGTTTAAGAACGATAGCTCTGTGCCGCGGCGCGAGCCTGGAGCGGCTGGTGTACGCGGGCGCTTGCGGCGTGTGCGACCCGCCGCGCCCCGGCGTGCGCGCCGCCGTGAGCACGCTGCGCCGCGCCGCCGTCGACGTCAAGATGGTGACCGGCGACGCGCGCCCCACGGCGCTCGCTGTCGCACAAATGGTCGGCTTGGACGTCCTGCACTCTCAATCTCTATCCGGCGAACAACTCGACTCGATGGCCGACGAAGAACTTGACCGCATTATCGATACGGTGAGCGTTTTCTACAGGGTGACGCCAAAGCACAAGCTTGCTATTGTGAAGTCTCTCCAGCGGCTCGGGAACATTGTCGGCATGACGGGTGACGGCGTCAACGACGGCGTGGCGCTGAAGCGGGCGGACATTGGCATTGCCATGGGCAAGAACGGCACCGACGTGTGCAAGGAGGCCGCCGACATGATCCTGGTCGATGATGACTTCGCCACCATCATAGCCGCAATCGAAGAAGGAAAATCGATATTCTACAACATTGGAAACTTCGTGAGGTTCCAACTGTCCACCTCGATAGCGGCGTTGTCGCTCATCGCTCTGGCAACACTGATGGGCGTTCCCAACCCGCTGAACGCTATGCAGATTCTCTGGATCAATATTATAATGGACGGTCCGCCGGCGCAGTCGCTGGGCGTGGAGCCCGTGGACCACGAGGTGGTGGGGCTGGGCCCGCGCGACACGCGGCGCCGCCTGCTGTCCCGCCCGCTGCTGCTCAACGTGCTGCTGTCCGCCGCCATCATCATCGCCGGCACGCTGTGGGTCTTCAATCGTGAGATGTCGGACAACACGATCACGCCCCGGGACACGACCATGACGTTCACGTGCTTCGTGCTGTTCGACATGTTCAACGCGCTGTCGTGCCGCTCGCAGACCAAGTCCGTGTTCGAGGTGGGGCTGCTCTCCAACCGCATGTTCCTGGCCGCCGTCACGCTGAGTCTGCTGGGCCAGGCCCTGGTTATTTACTTCCCGCCGTTGCAGAGCGTGTTCCAGACGGAGGCGCTCACAGCGCACGATATACTGTTCCTGGTCGGTCTTACGTCGAGCGTGTTTATAGTAAGCGAAATTAAAAAGCTTATCGAACGCACCCTGAAGAAGCGCGTCTACGGCAAGTACGCTGCTAAGGCCCACGACGCTATGGACTTTGTATGA

Protein

MWISAVESSILTWEEVSERLSVDVRRGLSWREANDRMNFVGANEFQVKEQDPLWKKYIEQFQNPLILLLLGSAVVSVCMRQFDDAISITVAIIIVVTVAFVQEYRSEKSLEELNKLVPPSCNCLREGSLEHFLARNLVPGDIVHLNVGDRVPADLRLFDSTDLAIDESSFTGETEPAVKNIVPNKAAAGRVNKDNIAFMGTLVRCGNAKGIVVSTGERSEFGDIFRMMQAEEAPKTPLQKSMDTLGGQLSMYSFCIIGFIMITGWLQGKALQEMFTIGVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNAIVKKLPTVETLGCVNVICSDKTGTLTKNEMTVTTIATSGGHIAEVTGTGYNGRGDIQLRAYKGRDLDVARMGVTSMLEVAVLCNNAHIRDETLYGQPTEGALVACAMKHGLRDLREQYTRLHEIPFSSETKMMVVKCAPKFSDGGKEELFVKGAVEKVLPLCTQYIDSAGNYAPLTNEKQNEILAEVYNIGRMGLRTIALCRGASLERLVYAGACGVCDPPRPGVRAAVSTLRRAAVDVKMVTGDARPTALAVAQMVGLDVLHSQSLSGEQLDSMADEELDRIIDTVSVFYRVTPKHKLAIVKSLQRLGNIVGMTGDGVNDGVALKRADIGIAMGKNGTDVCKEAADMILVDDDFATIIAAIEEGKSIFYNIGNFVRFQLSTSIAALSLIALATLMGVPNPLNAMQILWINIIMDGPPAQSLGVEPVDHEVVGLGPRDTRRRLLSRPLLLNVLLSAAIIIAGTLWVFNREMSDNTITPRDTTMTFTCFVLFDMFNALSCRSQTKSVFEVGLLSNRMFLAAVTLSLLGQALVIYFPPLQSVFQTEALTAHDILFLVGLTSSVFIVSEIKKLIERTLKKRVYGKYAAKAHDAMDFV

Description

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.

Catalytic Activity

ATP + Ca(2+)(in) + H2O = ADP + Ca(2+)(out) + H(+) + phosphate

Similarity

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.

Uniprot

A0A2A4JUZ5   A0A2A4JVP8   A0A3S2TKU5   A0A212ELX2   A0A2H1W7T5   A0A194PV50   + More
A0A067RKU6   A0A2J7QLK3   A0A154PIL0   F4WDE3   A0A195BX72   A0A158NIS0   A0A151XDU7   A0A2A3E8J9   V9ICI9   A0A087ZVD3   A0A0J7N4A6   A0A195FTI2   A0A195CBY4   A0A0L7QSG7   E2BCM5   A0A0C9RCC7   E2AVH1   A0A151J7B8   A0A232F7A3   E0VUC0   A0A026W8F2   A0A0V0G3A0   A0A023F4S7   A0A224XJ47   A0A069DXQ9   A0A1B6ESV6   A0A1B6MH31   A0A1B6ML36   A0A1B6LFZ6   A0A1A9YUJ2   A0A0L0CEA4   A0A1I8MMU0   A0A2M4CUJ8   A0A1B6DL98   A0A2M4CT61   A0A1I8MMU8   A0A1B6EBU5   D6W6C6   A0A0M5JBF6   A0A1I8Q2K0   A0A1I8Q2J8   A0A1Q3F859   A0A1B0ESK7   A0A1Q3F7K6   A0A1Q3F825   A0A0K8TS12   A0A1S4F525   A0A0Q9XM47   A0A1Y1LA79   A0A1Y1L5I9   A0A0Q9XN45   A0A0Q9WWF4   A0A0Q9WSV2   A0A0Q9WKX5   A0A0Q5UK69   B4LDX9   A0A034VCB0   A0A0Q9WJU5   A0A0Q9XCR5   A0A0Q9XPK7   A0A0Q5UKR4   A0A0K8V5L8   B4KYJ6   A0A0Q9WJE3   A0A3B0JLL9   W8B6F5   A0A0R1E2R8   B3NEF6   W8BH99   A0A084WM47   A0A0Q5U613   A0A1W4UDS7   A0A1L8DF23   A0A1L8DEW2   A0A0R1E4G1   A0A182J722   A0A0R1E4B3   A0A1W4URA0   A0A0J9RZZ5   Q2M0Q6   C1C5A0   A0A1W4UR16   A0A0J9S025   A0A0J9S091   A0A0J9URQ8   Q9VNR2   B4PIQ1   A0A1B0DE25   B4IB41   Q8IPS6   Q7KTU2   B3MB86   A0A0P8YCD4   A0A1W4USS9  

EC Number

7.2.2.10

Pubmed

22118469    26354079    24845553    21719571    21347285    20798317    + More
28648823    20566863    24508170    30249741    25474469    26334808    26108605    25315136    18362917    19820115    26369729    17994087    28004739    18057021    25348373    24495485    17550304    24438588    22936249    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356   

EMBL

NWSH01000530    PCG75857.1    PCG75856.1    RSAL01000076    RVE48862.1    AGBW02013978    + More
OWR42461.1    ODYU01006900    SOQ49165.1    KQ459590    KPI97197.1    KK852567    KDR21210.1    NEVH01013243    PNF29463.1    KQ434924    KZC11673.1    GL888087    EGI67723.1    KQ976394    KYM93239.1    ADTU01017107    ADTU01017108    KQ982289    KYQ58428.1    KZ288345    PBC27602.1    JR038699    AEY58372.1    LBMM01010365    KMQ87515.1    KQ981285    KYN43199.1    KQ978068    KYM97603.1    KQ414757    KOC61582.1    GL447336    EFN86535.1    GBYB01004853    GBYB01005960    JAG74620.1    JAG75727.1    GL443112    EFN62566.1    KQ979695    KYN19729.1    NNAY01000743    OXU26721.1    AAZO01005477    DS235785    EEB16976.1    KK107364    QOIP01000007    EZA51926.1    RLU20962.1    GECL01003530    JAP02594.1    GBBI01002290    JAC16422.1    GFTR01008263    JAW08163.1    GBGD01000397    JAC88492.1    GECZ01028684    GECZ01010224    JAS41085.1    JAS59545.1    GEBQ01004717    JAT35260.1    GEBQ01003353    JAT36624.1    GEBQ01017361    JAT22616.1    CCAG010019616    CCAG010019617    JRES01000502    KNC30576.1    GGFL01004340    MBW68518.1    GEDC01010834    JAS26464.1    GGFL01004339    MBW68517.1    GEDC01021944    GEDC01001897    JAS15354.1    JAS35401.1    KQ971319    EFA11368.2    CP012525    ALC44544.1    GFDL01011284    JAV23761.1    AJWK01004433    AJWK01004434    AJWK01004435    AJWK01004436    GFDL01011500    JAV23545.1    GFDL01011382    JAV23663.1    GDAI01000888    JAI16715.1    CH933809    KRG06372.1    GEZM01064051    JAV68845.1    GEZM01064052    JAV68844.1    KRG06366.1    CH940647    KRF84672.1    KRF84673.1    KRF84678.1    CH954178    KQS44438.1    EDW70022.1    KRF84677.1    GAKP01019235    GAKP01019234    JAC39717.1    KRF84674.1    KRG06374.1    KRG06375.1    KQS44439.1    GDHF01018143    GDHF01009762    JAI34171.1    JAI42552.1    EDW18807.1    KRF84675.1    OUUW01000002    SPP76290.1    GAMC01013942    GAMC01013941    JAB92613.1    CM000159    KRK02515.1    EDV52791.2    GAMC01013944    GAMC01013943    JAB92611.1    ATLV01024384    KE525351    KFB51291.1    KQS44437.1    GFDF01009099    JAV04985.1    GFDF01009098    JAV04986.1    KRK02516.1    KRK02514.1    CM002912    KMZ01227.1    CH379069    EAL30874.3    BT082029    AE014296    ACO72866.1    ACZ94767.1    KMZ01229.1    KMZ01228.1    KMZ01231.1    AAF51860.1    EDW95559.1    AJVK01014701    AJVK01014702    AJVK01014703    AJVK01014704    CH480826    EDW44504.1    BT133078    AAN12202.1    AEX93163.1    AAF51858.2    CH902618    EDV41387.2    KPU79086.1   

Proteomes

UP000218220    UP000283053    UP000007151    UP000053268    UP000027135    UP000235965    + More
UP000076502    UP000007755    UP000078540    UP000005205    UP000075809    UP000242457    UP000005203    UP000036403    UP000078541    UP000078542    UP000053825    UP000008237    UP000000311    UP000078492    UP000215335    UP000009046    UP000053097    UP000279307    UP000092444    UP000037069    UP000095301    UP000007266    UP000092553    UP000095300    UP000092461    UP000009192    UP000008792    UP000008711    UP000268350    UP000002282    UP000030765    UP000192221    UP000075880    UP000001819    UP000000803    UP000092462    UP000001292    UP000007801   

PRIDE

C1C5A0    Q9VNR2    Q8IPS6    Q7KTU2   

Pfam

PF00689   Cation_ATPase_C        + More
PF00690   Cation_ATPase_N

Interpro

IPR023299   ATPase_P-typ_cyto_dom_N        + More
IPR030336   ATP2C1       
IPR006413   P-type_ATPase_IIA_PMR1       
IPR023298   ATPase_P-typ_TM_dom_sf       
IPR006068   ATPase_P-typ_cation-transptr_C       
IPR008250   ATPase_P-typ_transduc_dom_A_sf       
IPR001757   P_typ_ATPase       
IPR023214   HAD_sf       
IPR036412   HAD-like_sf       
IPR018303   ATPase_P-typ_P_site       
IPR004014   ATPase_P-typ_cation-transptr_N       
IPR030334   ATP2C2       

SUPFAM

SSF81660   SSF81660        + More
SSF81665   SSF81665       
SSF56784   SSF56784       
SSF81653   SSF81653       

Gene 3D

3.40.1110.10     3.40.50.1000    

ProteinModelPortal

A0A2A4JUZ5   A0A2A4JVP8   A0A3S2TKU5   A0A212ELX2   A0A2H1W7T5   A0A194PV50   + More
A0A067RKU6   A0A2J7QLK3   A0A154PIL0   F4WDE3   A0A195BX72   A0A158NIS0   A0A151XDU7   A0A2A3E8J9   V9ICI9   A0A087ZVD3   A0A0J7N4A6   A0A195FTI2   A0A195CBY4   A0A0L7QSG7   E2BCM5   A0A0C9RCC7   E2AVH1   A0A151J7B8   A0A232F7A3   E0VUC0   A0A026W8F2   A0A0V0G3A0   A0A023F4S7   A0A224XJ47   A0A069DXQ9   A0A1B6ESV6   A0A1B6MH31   A0A1B6ML36   A0A1B6LFZ6   A0A1A9YUJ2   A0A0L0CEA4   A0A1I8MMU0   A0A2M4CUJ8   A0A1B6DL98   A0A2M4CT61   A0A1I8MMU8   A0A1B6EBU5   D6W6C6   A0A0M5JBF6   A0A1I8Q2K0   A0A1I8Q2J8   A0A1Q3F859   A0A1B0ESK7   A0A1Q3F7K6   A0A1Q3F825   A0A0K8TS12   A0A1S4F525   A0A0Q9XM47   A0A1Y1LA79   A0A1Y1L5I9   A0A0Q9XN45   A0A0Q9WWF4   A0A0Q9WSV2   A0A0Q9WKX5   A0A0Q5UK69   B4LDX9   A0A034VCB0   A0A0Q9WJU5   A0A0Q9XCR5   A0A0Q9XPK7   A0A0Q5UKR4   A0A0K8V5L8   B4KYJ6   A0A0Q9WJE3   A0A3B0JLL9   W8B6F5   A0A0R1E2R8   B3NEF6   W8BH99   A0A084WM47   A0A0Q5U613   A0A1W4UDS7   A0A1L8DF23   A0A1L8DEW2   A0A0R1E4G1   A0A182J722   A0A0R1E4B3   A0A1W4URA0   A0A0J9RZZ5   Q2M0Q6   C1C5A0   A0A1W4UR16   A0A0J9S025   A0A0J9S091   A0A0J9URQ8   Q9VNR2   B4PIQ1   A0A1B0DE25   B4IB41   Q8IPS6   Q7KTU2   B3MB86   A0A0P8YCD4   A0A1W4USS9  

PDB

6HEF     E-value=8.62043e-106,     Score=984

KEGG

101743471    K01537 P-type Ca2+ transporter type 2C [EC:7.2.2.10] | (RefSeq) calcium-transporting ATPase type 2C

GO

GO:0016021   GO:0005388   GO:0005524   GO:0006816   GO:0008553   GO:0006874   GO:0015410   GO:0070588   GO:0000139   GO:0051208   GO:0042044   GO:0005794   GO:0005783   GO:0005777   GO:0019722   GO:0012505   GO:0000166   GO:0046872   GO:0004813   GO:0006419   GO:0015923   GO:0005634   GO:0006260  

PANTHER

PTHR42861:SF2   PTHR42861:SF23  

Subcellular location

Membrane  

Length:

904

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

170.05112

Exp number, first 60 AAs:

0.40755

Total prob of N-in:

0.28775

outside

1  -  243

TMhelix

244  -  266

inside

267  -  278

TMhelix

279  -  301

outside

302  -  691

TMhelix

692  -  714

inside

715  -  757

TMhelix

758  -  777

outside

778  -  791

TMhelix

792  -  809

inside

810  -  820

TMhelix

821  -  843

outside

844  -  857

TMhelix

858  -  877

inside

878  -  904

 

 

Pi

249.279445

Theta

168.927373

Tajima's D

0.647142

CLR

1.312067

CSRT

0.559622018899055

Interpretation

Uncertain