Gene

KWMTBOMO06449  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011607

Annotation

beta-1?3-glucan_recognition_protein_3_precursor_[Bombyx_mori]

Location

Bomo_Chr11(+):7339051-7353716      View in EpiBrowser

Full name

Beta-1,3-glucan-binding protein       + More
Beta-1,3-glucan-binding protein 2      
Beta-1,3-glucan-binding protein 1      
Gram-negative bacteria-binding protein 3      

Alternative Name

Beta-1,3-glucan recognition protein
Beta-1,3-glucan recognition protein 2
Beta-1,3-glucan recognition protein 1

Location in the cell

Cytoplasmic   Reliability : 1.341 Mitochondrial   Reliability : 1.19

CDS

ATGTTCTTCAAAATTATTATATTAAGTGTGTTAGTCACAATATGTTCTGCGCAACCCAGAGCCGCCCAATACATCGTCCCTCCAGCTAAACTTGAAGCTATATATCCAGCTGGATTAAGAGTAACAGTGCCAGACGATGGTTTCTCGCTCTTCGCCTTTCACGGCAAGCTCAACGAAGAGATGGAAGGCCTGGAATCGGGGCATTGGTCCAGGGACATCACTAAAGCCAAAAACGGCGTTTGGACGTTCAGAGACAGAAATGCTCAGCTAAAACTGGGAGATAAGATTTATTTCTGGACGTATGTAATCAAGGATGGCCTCGGATATAGGCAGGATAACGGCGAATGGACTGTAACAGAATTCGTCAATGAAAATGGGAATCCAGTAGACGTAGCCAACCCACCTGTGGCCACATCTACCACGGGTCCACTGCAGATACCCCAACAAGCCAGCACTCCTATCGTTAGACCGGAACAGACGTGCCAAACGTCAGAAACAGTGGTCCAAGGCCGCGATAAAATCTGTAAGGGAACTTTGATCTTCAGTGACGAGTTTGAAAAGAATAGCCTTAAAGATTTGACGAGTTGGGGAGCTGAAGTTAGATTTCCTGAAGAACCGGATTATCCATTCAATGTCTACACAACTGATGGGACCATCGGCTTTGATTCCGGATCTTTGATCATCAGTCCGGTGCTTTTGGAGAGTAAATTCAGTGAAGACAAGATTTATCAAGACCTTGATTTGACGAACAGATGCACTGGCCAGATCGACACAACGGAGTGCAAAAGAGTGGCTTCTGGATCACAAATTCTTCCGCCAGTTATGACCGGGAAAGTGACAACTAGACACAAATTCGGCTTCAAATATGGAAGGATTGAGGTTCGAGTTAAGCTACCTGCTGGAAACTGGTTGATTCCTGAAGTCAACTTGGAGCCACACGAGAAGATGTACGGTCCGCGCCGCTACGAGTCCGGCTTGATGCGTATCGCCTTCACGAGAGGAAACGCTGTCTTCAGCAAGAAACTGTACGCTGGACCCGTTCTATCCGACACCGAGCCGTTCAGGTCGAAGCTAATGAAAGAGAAACTCGGCATCGAGAACTGGAATAAGGAATATCATAATTATACAATGATTTGGAAGCCTAATGGCATTGAAGTTTTGGTTGATGGAGAACAGTTCGGTGTAGTGGATCCAGGTGAAGGCTTCTATACTGTTGGCCGGCAGAATGCAGTACCTCATGCAGCCCAATGGCTCAAAGGAACAATTATGGCTCCACTGGATCAGATCTTCTATATCTCTCTCGGTCTCCGCGTTGGTGGCGTTCACGATTTCACGGATAATCCGGATAAGCCCTGGAAGAATAGGAACAGCAAAGCAATGCTGGCCTTCTGGAACGACAGGACTAACTGGTTGCCGACGTGGTACGATGCGGCCATGAGGGTTGATTACGTCAGAGTTTATGCACTTTAA

Protein

MFFKIIILSVLVTICSAQPRAAQYIVPPAKLEAIYPAGLRVTVPDDGFSLFAFHGKLNEEMEGLESGHWSRDITKAKNGVWTFRDRNAQLKLGDKIYFWTYVIKDGLGYRQDNGEWTVTEFVNENGNPVDVANPPVATSTTGPLQIPQQASTPIVRPEQTCQTSETVVQGRDKICKGTLIFSDEFEKNSLKDLTSWGAEVRFPEEPDYPFNVYTTDGTIGFDSGSLIISPVLLESKFSEDKIYQDLDLTNRCTGQIDTTECKRVASGSQILPPVMTGKVTTRHKFGFKYGRIEVRVKLPAGNWLIPEVNLEPHEKMYGPRRYESGLMRIAFTRGNAVFSKKLYAGPVLSDTEPFRSKLMKEKLGIENWNKEYHNYTMIWKPNGIEVLVDGEQFGVVDPGEGFYTVGRQNAVPHAAQWLKGTIMAPLDQIFYISLGLRVGGVHDFTDNPDKPWKNRNSKAMLAFWNDRTNWLPTWYDAAMRVDYVRVYAL

Description

Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan, causing aggregation of invading micro-organisms and activation of the phenoloxidase cascade.
Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and lipoteichoic acid and causes aggregation of invading micro-organisms. Binding to beta-1,3-glucan activates the phenoloxidase cascade.
Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade.
Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade. Causes aggregation of invading micro-organisms.
Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade (By similarity).

Subunit

Monomer.

Similarity

Belongs to the insect beta-1,3-glucan binding protein family.

Keywords

3D-structure   Direct protein sequencing   Glycoprotein   Immunity   Innate immunity   Secreted   Signal   Complete proteome   Reference proteome  

Feature

chain  Beta-1,3-glucan-binding protein

Uniprot

B5BSX8   H9JQ02   H9AA72   Q8MU95   A0A2W1BZR7   A0A194Q1C0   + More
A0A0N1PIG9   A0A3S2L9V1   A0A2A4JGS8   Q8ISB6   A0A346RAD2   A0A194PW19   B7SVL3   B7SVK9   S4NX93   A0A212ESM0   F2YLD9   A0A0N0PD03   A0A2H1WUA9   A0A0N1IPP2   I4DNK4   A0A194PUW2   A0A212ELU9   A0A0L7LKY4   A0A2H1WSV4   Q0E666   H9JQ03   A0A194PUV7   Q9NL89   A0A2A4JH28   A0A2W1BWP9   B7SVL2   G3MVG5   I3RJG9   A0A0D3L473   B7SVK4   I4DP05   B7SVK8   A0A194PWQ7   Q9NJ98   A0A2W1C0X2   B7SVL4   A0A2A4JIQ0   G5DE93   B7SVK6   A0A2H1WUD7   G3MVG4   B3NBL7   A0A2A4JI75   A0A2W1BUN3   B4QMM7   A8E788   B5X538   Q9NHA8   B4HK50   B4PFH1   A0A2J7QLS7   B3M5X3   B4KZH1   A0A3B0JVG9   B4MMC4   B4LEW9   Q29DZ2   A0A1W4VCK9   B4J3L1   A0A1Y1JZ37   A0A1Y1JZ48   A0A194PV45   A0A0K8W7M8   A0A034VYC5   D6WIF9   A0A1Y1K3B6   A0A0A1XKC9   A0A067RND0   J3JUM4   A0A2W1BUW1   A0A1W4XH40   A0A0L0C2S5   A0A1I8NZT4   A0A1I8PY92   N6TB38   H8YU83   U4UDM5   A0A2A4JIM4   A0A1I8M2R2   W8AU77   A0A3F2YU17   Q76DI2   A0A1A9ZTQ7   W5JFT8   A0A182GFY0   A0A182MYU8   Q17NM6   A0A182MML6   A0A1Y9IW14   A0A3F2Z1Y8   A0A1Y1K2A1   A0A1S4H971  

Pubmed

18840462    19121390    12770576    28756777    26354079    14976985    + More
29910977    19033442    23622113    22118469    22651552    26227816    10671539    3136171    21910994    10713054    17994087    22936249    10827089    17103056    10731132    12537572    17550304    15632085    28004739    25348373    18362917    19820115    25830018    24845553    22516182    26108605    23537049    25315136    24495485    12923175    20920257    23761445    26483478    17510324    12364791   

EMBL

AB436166    BAG70413.1    BABH01012373    JN880424    AFC35297.1    AF532603    + More
AAM95970.1    KZ149896    PZC78757.1    KQ459590    KPI97195.1    KQ460391    KPJ15398.1    RSAL01000076    RVE48856.1    NWSH01001422    PCG71285.1    AY135522    AAN10151.1    MH200922    AXS59132.1    KPI97193.1    EU770382    ACI32826.1    EU770378    ACI32822.1    GAIX01012252    JAA80308.1    AGBW02012766    OWR44496.1    JF313110    ADZ93428.1    KPJ15397.1    ODYU01011077    SOQ56587.1    KPJ15399.1    AK402982    BAM19494.1    KPI97196.1    AGBW02013978    OWR42456.1    JTDY01000692    KOB76198.1    ODYU01010749    SOQ56056.1    AM265582    CAK22401.1    KPI97191.1    AB026441    BAA92243.1    PCG71281.1    PZC78761.1    EU770381    ACI32825.1    HM459596    ADZ45541.1    JQ692072    AFK24449.1    JQ218446    AFU52688.1    EU770373    ACI32817.1    AK403229    BAM19645.1    EU770377    ACI32821.1    KPI97194.1    AF177982    AAF44011.1    PZC78760.1    EU770383    ACI32827.1    PCG71282.1    JN641797    AEQ33590.1    EU770375    ACI32819.1    SOQ56586.1    HM459595    ADZ45540.2    CH954178    EDV50613.1    PCG71284.1    PZC78758.1    CM000363    CM002912    EDX09781.1    KMY98515.1    BT031030    ABV82412.1    BT046157    ACI46545.1    AF228474    AM050231    AM050232    AM050233    AM050234    AM050235    AM050236    AM050237    AM050238    AM050239    AM050240    AM050241    AM050242    AE014296    AAF33851.1    AAF50349.1    CH480815    EDW40786.1    CM000159    EDW93097.1    NEVH01013243    PNF29498.1    CH902618    EDV39663.1    CH933809    EDW17898.1    OUUW01000002    SPP76731.1    CH963847    EDW73269.1    CH940647    EDW69138.1    CH379070    EAL30271.1    CH916366    EDV96213.1    GEZM01096755    JAV54582.1    GEZM01096759    JAV54579.1    KPI97192.1    GDHF01005232    JAI47082.1    GAKP01011860    JAC47092.1    KQ971334    EFA01356.1    GEZM01096757    JAV54580.1    GBXI01002972    JAD11320.1    KK852567    KDR21214.1    BT126939    AEE61901.1    PZC78759.1    JRES01001077    KNC25719.1    APGK01044526    APGK01044527    KB741026    ENN74953.1    JF915525    AFD54027.1    KB632309    ERL92074.1    PCG71283.1    GAMC01016768    JAB89787.1    AB108841    BAC99308.1    ADMH02001279    ETN63242.1    JXUM01060643    KQ562111    KXJ76671.1    CH477198    EAT48288.2    AXCM01006744    GEZM01096756    JAV54581.1    AAAB01008986   

Proteomes

UP000005204    UP000053268    UP000053240    UP000283053    UP000218220    UP000007151    + More
UP000037510    UP000008711    UP000000304    UP000000803    UP000001292    UP000002282    UP000235965    UP000007801    UP000009192    UP000268350    UP000007798    UP000008792    UP000001819    UP000192221    UP000001070    UP000007266    UP000027135    UP000192223    UP000037069    UP000095300    UP000019118    UP000030742    UP000095301    UP000075881    UP000092445    UP000000673    UP000069940    UP000249989    UP000075884    UP000008820    UP000075883    UP000075920    UP000076407   

PRIDE

B5BSX8    H9JQ02    Q8ISB6    H9JQ03    Q9NL89    B5X538    + More
Q9NHA8    Q76DI2   

Pfam

PF15886   CBM39        + More
PF00722   Glyco_hydro_16
PF16165   Ferlin_C
PF00168   C2

Interpro

IPR031756   BGBP_N        + More
IPR013320   ConA-like_dom_sf       
IPR000757   GH16       
IPR035806   GH16_GRP_C       
IPR000008   C2_dom       
IPR037725   C2F_Ferlin       
IPR035892   C2_domain_sf       
IPR032362   Ferlin_C       
IPR012968   FerIin_dom       
IPR037721   Ferlin       

SUPFAM

SSF49899   SSF49899       

Gene 3D

2.60.40.150    

CDD

cd02179  GH16_beta_GRP
cd08374  C2F_Ferlin

ProteinModelPortal

B5BSX8   H9JQ02   H9AA72   Q8MU95   A0A2W1BZR7   A0A194Q1C0   + More
A0A0N1PIG9   A0A3S2L9V1   A0A2A4JGS8   Q8ISB6   A0A346RAD2   A0A194PW19   B7SVL3   B7SVK9   S4NX93   A0A212ESM0   F2YLD9   A0A0N0PD03   A0A2H1WUA9   A0A0N1IPP2   I4DNK4   A0A194PUW2   A0A212ELU9   A0A0L7LKY4   A0A2H1WSV4   Q0E666   H9JQ03   A0A194PUV7   Q9NL89   A0A2A4JH28   A0A2W1BWP9   B7SVL2   G3MVG5   I3RJG9   A0A0D3L473   B7SVK4   I4DP05   B7SVK8   A0A194PWQ7   Q9NJ98   A0A2W1C0X2   B7SVL4   A0A2A4JIQ0   G5DE93   B7SVK6   A0A2H1WUD7   G3MVG4   B3NBL7   A0A2A4JI75   A0A2W1BUN3   B4QMM7   A8E788   B5X538   Q9NHA8   B4HK50   B4PFH1   A0A2J7QLS7   B3M5X3   B4KZH1   A0A3B0JVG9   B4MMC4   B4LEW9   Q29DZ2   A0A1W4VCK9   B4J3L1   A0A1Y1JZ37   A0A1Y1JZ48   A0A194PV45   A0A0K8W7M8   A0A034VYC5   D6WIF9   A0A1Y1K3B6   A0A0A1XKC9   A0A067RND0   J3JUM4   A0A2W1BUW1   A0A1W4XH40   A0A0L0C2S5   A0A1I8NZT4   A0A1I8PY92   N6TB38   H8YU83   U4UDM5   A0A2A4JIM4   A0A1I8M2R2   W8AU77   A0A3F2YU17   Q76DI2   A0A1A9ZTQ7   W5JFT8   A0A182GFY0   A0A182MYU8   Q17NM6   A0A182MML6   A0A1Y9IW14   A0A3F2Z1Y8   A0A1Y1K2A1   A0A1S4H971  

PDB

2KHA     E-value=3.24526e-56,     Score=554

KEGG

100188963    K20692 gram-negative bacteria-binding protein 3 | (RefSeq) BGRP3; beta-1,3-glucan recognition protei

PATHWAY

04624    Toll and Imd signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0004553   GO:0005975   GO:0030246   GO:0005576   GO:0002752   GO:0045087   GO:0008329   GO:0045088   GO:0009986   GO:0001872   GO:0032491   GO:0045752   GO:0001530   GO:0002758   GO:0002221   GO:0016021   GO:0042742   GO:0006508   GO:0015074   GO:0004813   GO:0006419   GO:0015923   GO:0005634   GO:0006260  

PANTHER

PTHR12546  

Subcellular location

Secreted  

SignalP

Position:   1 - 17,         Likelihood:  0.993212

 

 

Length:

489

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.30341

Exp number, first 60 AAs:

0.29496

Total prob of N-in:

0.01502

outside

1  -  489

 

 

Pi

224.430198

Theta

177.611889

Tajima's D

0.947403

CLR

0.347366

CSRT

0.64096795160242

Interpretation

Uncertain