Gene

KWMTBOMO06429

Annotation

Alanyl-tRNA_editing_protein_Aarsd1_[Papilio_xuthus]

Location

Bomo_Chr11(+):6970651-6977830      View in EpiBrowser

Full name

Alanyl-tRNA editing protein Aarsd1      

Alternative Name

Alanyl-tRNA deacylase alaX
Alanyl-tRNA synthetase domain-containing protein 1

Location in the cell

Cytoplasmic   Reliability : 3.908

CDS

ATGGTTTTCAAATGTCAAGAGGATAGTTTTCTGACTGAGTATCAATCTAAAGTACTGCAGTGTGAGCCAACCAAAGAACCAATAGTAGATTATGGAAAAACATCATTATTTGAAGGTTTCCAGATTATTTTAGAAAACACTATCCTCTTTCCAGCAGGAGGTGGACAGCCTCATGACATCGGCTGGTTGAATGATGTTGAAGTGTTGCAAGTTCTCCGGAAAGGTGACGAGGCACTCCACTTCACACGAGAGCCAATAGATGTGGGTATAGAGGTCAAACAAAAGGTCAATTGGAATAGAAGATTTGATCATATGCAGCAGCATTCTGGCCAGCATCTTTTATCGGCAATACTGGAGAAGCATCACAGCCTACCTACAACAAGCTGGTGGCTTGGTGCAGACGAGTCCTATGTCGAGATAGACTCTACGAAAGTGTCTGAACAGCAAATAAACGCTACCGAGAATTACTGTAATGAACTGATCAGAGCTGCTGTACCGGTCAGTGTGAAGATTTGCAAGTCTAATGATCCAGATTTAAATGAGGCTCACACAAGAGGTCTACCAAAGGATTGCATGGAAACTATACGGATTATATGCATTGGTGATATTGACGAAAACATGTGTTGCGGCACTCATGTCTCGAATCTAAGTCAACTCCAAATAATAAAAATAATTGGAGCAGAGCCGGGGAAGAAGGGAAAGACAAATTTAAAATTTTTAGTAGGCGAACGGGTGACGAAAACTTTTCAGCGCATGTTAGAAAGGGAGAAAGCTTTGACGGGGCTTTTGAAGGAAGCTACGCCTGAATTTAACAGGGCCGTGCTCAAAGGGCTGGAGGGCGAGGGAATGTTCGTGCTTCTGATCTCTGAGGACCCCGATAGGGCGAAGGAAGGGCAGATCATTATTCAAGGACCGGAGGAGCATTGTAAAGCGCTGGGAGACATGATAACTGAGATGCTGAAAGCGAAGGGCGCCTTCAAGAACGGCAGATTCCAAGGGAAAGCCAGTGATTTAGGAGCTGTTAATAAATGCAAGAAACTAGTCGAGGATTATTTTAATAAGTTAACATAG

Protein

MVFKCQEDSFLTEYQSKVLQCEPTKEPIVDYGKTSLFEGFQIILENTILFPAGGGQPHDIGWLNDVEVLQVLRKGDEALHFTREPIDVGIEVKQKVNWNRRFDHMQQHSGQHLLSAILEKHHSLPTTSWWLGADESYVEIDSTKVSEQQINATENYCNELIRAAVPVSVKICKSNDPDLNEAHTRGLPKDCMETIRIICIGDIDENMCCGTHVSNLSQLQIIKIIGAEPGKKGKTNLKFLVGERVTKTFQRMLEREKALTGLLKEATPEFNRAVLKGLEGEGMFVLLISEDPDRAKEGQIIIQGPEEHCKALGDMITEMLKAKGAFKNGRFQGKASDLGAVNKCKKLVEDYFNKLT

Description

Functions in trans to edit the amino acid moiety from incorrectly charged Ser-tRNA(Ala).
Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala).

Cofactor

Zn(2+)

Similarity

Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

Keywords

Complete proteome   Cytoplasm   Metal-binding   Phosphoprotein   Protein biosynthesis   Reference proteome   Zinc   Alternative splicing  

Feature

chain  Alanyl-tRNA editing protein Aarsd1
splice variant  In isoform 2.

Uniprot

A0A2W1BWM9   H9JPZ6   A0A2A4JPZ5   A0A194Q1A1   A0A212FK38   A0A3S2NH35   + More
A0A2A4JNL3   S4PCF0   A0A2K6P773   A0A069DTC8   A0A224XPM8   A0A287BF30   U6CU04   A0A3Q7WTY7   A0A384CXH7   M3YEX4   A0A3P4S6E8   W5P212   A0A2Y9JW55   A0A2P8XSC7   R4G469   A0A2Y9GE59   A0A2U3Y4J3   A0A2U3WNJ1   S7N8N6   A0A3Q7RC01   L9JZW5   A0A3Q7NG02   H0WNT0   A0A1S3ALM3   A0A2K5RRN3   A0A2K6EZS4   A0A067RCD3   Q3THG9   A0A023F7Z2   A0A2K5L4U1   A0A2K5RRT1   A0A250Y0C3   G1Q3X5   S4RC44   A0A2K5K453   A0A340WQM4   D6W6E4   A0A096P5W4   A0A2K5ZM01   F7GYX8   A0A2K5CIU5   A0A2K5WG23   F7C1U6   A0A2Y9EGC1   A0A3B3RBF5   A0A383ZRN4   R4GCQ3   A0A0D9S1D9   A0A341BA50   A0A2K6P786   A0A2K6CU90   A0A151PBP5   K9IXN6   G3HLZ7   M3ZA06   A0A2I3RZV4   A0A2Y9EBQ9   A0A2R9AN71   G3SH26   A0A2D0SAY0   A0A1U8BP04   A0A0P6J475   I3LWQ6   U3FLJ6   A0A2D4K0V5   A0A060W430   Q9BTE6   A0A2K6MD35   A0A3Q4I139   A0A3B1JW63   A0A3Q3VQR8   G1TF82   A0A3Q2ED27   G3U986   Q5XI97   A0A2I2UVG8   A0A286XTL5   M1ECH3   A0A2Y9M8A9   B5X319   A0A1W4Z9D1   A0A3P8S0Y7   A0A3B3I659   C3XTB1   A0A2J7PCY4   A0A2D4I7S2   A0A3P9MPE8   F6WHX9   W5N331   U3C0L3   T1JDQ2   A0A3B4BQL1  

Pubmed

28756777    19121390    26354079    22118469    23622113    25362486    + More
26334808    30723633    24813606    20809919    29403074    23385571    24845553    16141072    15489334    18172502    21183079    25474469    28087693    21993624    18362917    19820115    17431167    29240929    22293439    21804562    29704459    16136131    22722832    22398555    25243066    24755649    14702039    16625196    21269460    23186163    25186727    25329095    22673903    17975172    23236062    20433749    17554307    18563158    19892987   

EMBL

KZ149896    PZC78741.1    BABH01012403    BABH01012404    BABH01012405    NWSH01000889    + More
PCG73664.1    KQ459590    KPI97175.1    AGBW02008141    OWR54115.1    RSAL01000104    RVE47398.1    PCG73665.1    GAIX01004221    JAA88339.1    GBGD01001689    JAC87200.1    GFTR01005904    JAW10522.1    AEMK02000080    DQIR01106561    DQIR01160268    HDA62037.1    HAAF01002095    CCP73921.1    AEYP01079420    AEYP01079421    AEYP01079422    CYRY02045962    VCX41498.1    AMGL01018699    PYGN01001429    PSN34908.1    ACPB03016596    GAHY01001046    JAA76464.1    KE163747    EPQ13614.1    KB320934    ELW54722.1    AAQR03042648    AAQR03042649    AAQR03042650    AAQR03042651    KK852729    KDR17544.1    AK078016    AK136332    AK168281    BC005711    GBBI01001373    JAC17339.1    GFFV01002895    JAV37050.1    AAPE02024550    AAPE02024551    KQ971319    EFA11359.1    AHZZ02010402    AHZZ02010403    AHZZ02010404    AHZZ02010405    AQIA01028007    AQIA01028008    AQIA01028009    AQIA01028010    JSUE03016894    JSUE03016895    JSUE03016896    AQIB01145573    AKHW03000499    KYO46463.1    GABZ01006339    JAA47186.1    JH000499    RAZU01000248    EGW08069.1    RLQ62460.1    AACZ04038978    AC193256    AJFE02044597    AJFE02044598    AJFE02044599    AJFE02044600    AJFE02044601    AJFE02044602    AJFE02044603    CABD030037777    CABD030037778    CABD030037779    CABD030037780    GEBF01005448    JAN98184.1    AGTP01023523    GAMT01005233    GAMS01010815    GAMR01003507    GAMQ01000526    JAB06628.1    JAB12321.1    JAB30425.1    JAB41325.1    IACL01023128    LAB02371.1    FR904390    CDQ61862.1    AK295447    CR608238    AC055866    CH471152    BC004172    BC019324    AAGW02039774    BC083790    AANG04000144    AAKN02042422    JP004846    AER93443.1    BT045438    ACI33700.1    GG666462    EEN68700.1    NEVH01026401    PNF14196.1    IACK01081477    LAA80270.1    AHAT01023053    GAMS01010814    JAB12322.1    JH432108   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000283053    UP000233200    + More
UP000008227    UP000286642    UP000261680    UP000291021    UP000000715    UP000002356    UP000248482    UP000245037    UP000015103    UP000248481    UP000245341    UP000245340    UP000286640    UP000011518    UP000286641    UP000005225    UP000079721    UP000233040    UP000233160    UP000027135    UP000000589    UP000233060    UP000001074    UP000245300    UP000233080    UP000265300    UP000007266    UP000028761    UP000233140    UP000008225    UP000233020    UP000233100    UP000006718    UP000248484    UP000261540    UP000261681    UP000001646    UP000029965    UP000252040    UP000233120    UP000050525    UP000001075    UP000273346    UP000001073    UP000002277    UP000248480    UP000240080    UP000001519    UP000221080    UP000189706    UP000005215    UP000193380    UP000005640    UP000233180    UP000261580    UP000018467    UP000261620    UP000001811    UP000265020    UP000007646    UP000002494    UP000011712    UP000005447    UP000248483    UP000087266    UP000192224    UP000265080    UP000001038    UP000001554    UP000235965    UP000265180    UP000002281    UP000018468    UP000261440   

PRIDE

H9JPZ6    Q3THG9    G3HLZ7    Q9BTE6    Q5XI97   

Pfam

PF07973   tRNA_SAD        + More
PF00202   Aminotran_3
PF01411   tRNA-synt_2c

Interpro

IPR012947   tRNA_SAD        + More
IPR009000   Transl_B-barrel_sf       
IPR018163   Thr/Ala-tRNA-synth_IIc_edit       
IPR005814   Aminotrans_3       
IPR015422   PyrdxlP-dep_Trfase_dom1       
IPR015424   PyrdxlP-dep_Trfase       
IPR015421   PyrdxlP-dep_Trfase_major       
IPR018165   Ala-tRNA-synth_IIc_core       
IPR018164   Ala-tRNA-synth_IIc_N       
IPR007052   CS_dom       
IPR008978   HSP20-like_chaperone       

SUPFAM

SSF55186   SSF55186        + More
SSF50447   SSF50447       
SSF53383   SSF53383       
SSF49764   SSF49764       

Gene 3D

3.40.640.10     3.90.1150.10     2.60.40.790    

CDD

cd00610  OAT_like

ProteinModelPortal

A0A2W1BWM9   H9JPZ6   A0A2A4JPZ5   A0A194Q1A1   A0A212FK38   A0A3S2NH35   + More
A0A2A4JNL3   S4PCF0   A0A2K6P773   A0A069DTC8   A0A224XPM8   A0A287BF30   U6CU04   A0A3Q7WTY7   A0A384CXH7   M3YEX4   A0A3P4S6E8   W5P212   A0A2Y9JW55   A0A2P8XSC7   R4G469   A0A2Y9GE59   A0A2U3Y4J3   A0A2U3WNJ1   S7N8N6   A0A3Q7RC01   L9JZW5   A0A3Q7NG02   H0WNT0   A0A1S3ALM3   A0A2K5RRN3   A0A2K6EZS4   A0A067RCD3   Q3THG9   A0A023F7Z2   A0A2K5L4U1   A0A2K5RRT1   A0A250Y0C3   G1Q3X5   S4RC44   A0A2K5K453   A0A340WQM4   D6W6E4   A0A096P5W4   A0A2K5ZM01   F7GYX8   A0A2K5CIU5   A0A2K5WG23   F7C1U6   A0A2Y9EGC1   A0A3B3RBF5   A0A383ZRN4   R4GCQ3   A0A0D9S1D9   A0A341BA50   A0A2K6P786   A0A2K6CU90   A0A151PBP5   K9IXN6   G3HLZ7   M3ZA06   A0A2I3RZV4   A0A2Y9EBQ9   A0A2R9AN71   G3SH26   A0A2D0SAY0   A0A1U8BP04   A0A0P6J475   I3LWQ6   U3FLJ6   A0A2D4K0V5   A0A060W430   Q9BTE6   A0A2K6MD35   A0A3Q4I139   A0A3B1JW63   A0A3Q3VQR8   G1TF82   A0A3Q2ED27   G3U986   Q5XI97   A0A2I2UVG8   A0A286XTL5   M1ECH3   A0A2Y9M8A9   B5X319   A0A1W4Z9D1   A0A3P8S0Y7   A0A3B3I659   C3XTB1   A0A2J7PCY4   A0A2D4I7S2   A0A3P9MPE8   F6WHX9   W5N331   U3C0L3   T1JDQ2   A0A3B4BQL1  

PDB

3KEW     E-value=8.07353e-17,     Score=212

KEGG

101744960    K00827 alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase [EC:2.

PATHWAY

00250    Alanine, aspartate and glutamate metabolism - Bombyx mori (domestic silkworm)
00260    Glycine, serine and threonine metabolism - Bombyx mori (domestic silkworm)
00270    Cysteine and methionine metabolism - Bombyx mori (domestic silkworm)
00280    Valine, leucine and isoleucine degradation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0004812   GO:0005524   GO:0043039   GO:0003676   GO:0004813   GO:0030170   GO:0008483   GO:0006419   GO:0005737   GO:0002196   GO:0046872   GO:0002161   GO:0006450   GO:0016787   GO:0005634   GO:0000166   GO:0016876   GO:0015923   GO:0006260  

Subcellular location

Cytoplasm  

Length:

356

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00142

Exp number, first 60 AAs:

0.00142

Total prob of N-in:

0.01150

outside

1  -  356

 

 

Pi

214.886713

Theta

164.595774

Tajima's D

1.117803

CLR

0.522178

CSRT

0.690765461726914

Interpretation

Uncertain