Gene

KWMTBOMO06425

Pre Gene Modal

BGIBMGA011949

Annotation

Sodium-dependent_neutral_amino_acid_transporter_B(0)AT2_[Papilio_machaon]

Location

Bomo_Chr11(-):6893266-6910960      View in EpiBrowser

Full name

Transporter      

Location in the cell

PlasmaMembrane   Reliability : 4.952

CDS

ATGGCGAACACAGCGCATTTGATGAGACGACAGAGTTCGCGGGACCTTTACGCGCAGAGGTCTCTGGATCGGATGGAGATGAAGGAGCTGAGAGGACGCCTCGTTACGATGGAGAACGGGCAGCCCGCGCACAGGACTCATGTCATGTACGGAGCTACTAATGAGGCCTTTGAAGACACAAGCCCGAACAGACGCTCCTCCGAAACTCCTACCAGCAAAGGGAGTTCCGGTGAAGAACGTGCCGGTTTTAAGAATGAGGGAGCCGAGATAGAACGCGAGTCTTGGGATAGTAAATTGACCTTCCTACTCGCAACCGTCGGATATGCTGTCGGCCTAGGAAACGTTTGGCGATTCCCATATTTAGCCCAAAAGAACGGCGGCGGTGCGTTTCTCATACCGTACTTCGTAATGCTGGCTATCGAGGGCATACCGATATTTTACTTGGAATTGGCAATCGGTCAGAGATTAAGGAAAGGCGCTATCGGCGTTTGGCATCAAGTATCCCCTTACCTCGGAGGTATCGGCATTAGTTCCGCCGTGGTTTCTTTCAACGTGGCTTTGTACTACAACTCTATAATAGCTTGGTGCCTTTTCTACTTCGCTCAGAGTTTCCAGGCGGAACTACCTTGGTCTGAATGCCCGAAGAAATACTTCCCGAACGGCTCTTACACAAGCGAACCGGAGTGCGCGAAAAGCAGCCCCACCCAATACTTTTGGTATCGAACAACTCTTCAAATATCCGAAGACATAAACTATCCGGAAACGTTCAATTACAAAATAGCTCTTGCTCTAGTCATTGCTTGGATTCTGGTCTACCTATGTATGATCAAAGGGATTGCGTCATCGGGGAAGGTAGTGTACGTGACCGCAACATTCCCATACATAGTCCTTGTTATATTTTTCTTTAGAGGCATCACATTGAAAGGCATGAGCGACGGACTAATACATCTATTCACTCCGAAGTGGCACACGATTTTAGACCCTGTGGTGTGGCTAGAAGCGGGCACACAGATCTTCTTTTCGCTTGGACTGGCTTTTGGTGGTTTAATAGCCTTCTCTTCGTACAACCCGGTCGATAACAACTGCTACAGAGACGCCATTATGGTCTCCATGACAAATTGTCTAACATCGATGTTCGCTGGTATCGTTGTCTTTTCTATAATTGGCTTCAAAGCAACTATGATCTATGAGAAATGTTTGGAGATCAGGAACGAGACTTTATTGGAGATGTTTGGCTCGTCATACAAGTCAATGGTGTTTCCTGAGGCTGGGGAATCGGTGACGATCGATAAAAACGGAACTATAACGAATTTGTTAATGCCACTATTGCCTGTTTGCGATTTGCAGAAGGAACTCGATAATACCGCATCCGGGACCGGTTTAGCGTTCATCATCTTCACCGAGGCCATTAACCAATTCCCAGGCGCTCAATTTTGGTCAGTCCTCTTCTTCCTGATGCTTTTCACCCTCGGGATCGATTCCCAGTTTGGGACCCTTGAGGGCGTAGTCACTTCCATCGTGGATATGAAGCTGTTCCCGAACCTGCGCAAGGAGTACCTGACCGGAGGGCTGTGCTTGCTCTGTTGCTTGCTGTCAATGGGCTTCGCTCATGGTGCAGGCAGCTATATATTCCTGCTCTTCGACATGTATAGCGGGAACTTCCCGCTACTGATCATTGCGTTCTTTGAATGCGTCGGGATCGCTTACGTGTACGGAGTGAAGAGGTGA

Protein

MANTAHLMRRQSSRDLYAQRSLDRMEMKELRGRLVTMENGQPAHRTHVMYGATNEAFEDTSPNRRSSETPTSKGSSGEERAGFKNEGAEIERESWDSKLTFLLATVGYAVGLGNVWRFPYLAQKNGGGAFLIPYFVMLAIEGIPIFYLELAIGQRLRKGAIGVWHQVSPYLGGIGISSAVVSFNVALYYNSIIAWCLFYFAQSFQAELPWSECPKKYFPNGSYTSEPECAKSSPTQYFWYRTTLQISEDINYPETFNYKIALALVIAWILVYLCMIKGIASSGKVVYVTATFPYIVLVIFFFRGITLKGMSDGLIHLFTPKWHTILDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPVDNNCYRDAIMVSMTNCLTSMFAGIVVFSIIGFKATMIYEKCLEIRNETLLEMFGSSYKSMVFPEAGESVTIDKNGTITNLLMPLLPVCDLQKELDNTASGTGLAFIIFTEAINQFPGAQFWSVLFFLMLFTLGIDSQFGTLEGVVTSIVDMKLFPNLRKEYLTGGLCLLCCLLSMGFAHGAGSYIFLLFDMYSGNFPLLIIAFFECVGIAYVYGVKR

Similarity

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.

Uniprot

A0A2H1VB97   A0A0N1PI46   A0A2A4J2I1   A0A2W1BYK9   A0A194PUT7   N6TH77   + More
D6WF78   A0A3L8DFG3   F4WDU6   A0A067QK51   V9IIT8   A0A0M9A559   A0A087ZZD7   E2B634   A0A154PJZ4   E2AIM7   A0A232ES14   A0A2J7PQJ5   A0A195DUT1   A0A195FFX7   A0A195CRF3   A0A151XIK1   A0A026WYB0   E9IDL1   T1I2Z2   A0A195AW29   E0VLT1   A0A2R7WZI5   A0A1W4XVE7   A0A0J7L8S8   A0A2A3EK71   A0A0L7R0Y6   A0A084VQ96   A0A182RKR6   A0A1I8MX21   A0A182V1D1   A0A182TEQ0   A0A182IA05   A0A182M6Y4   A0A182Q4H7   A0A182W5V4   A0A182KAF6   Q29ID8   A0A3B0KLZ4   A0A1A9ULI3   A0A182FK95   B4M1X1   B4JIW6   A0A0L0C570   B7Z122   B4ND29   B3NSP8   A0A182GTQ1   B4Q0J8   A0A182YCR3   B4R458   A0A1I8P2J0   B3N065   W8BPP3   A0A182N0X1   A0A1A9W244   A0A1W4V8C1   B4L8L5   A0A0M4EXL4   A0A0P5AI26   A0A0P6JIK8   A0A182IQ63   A0A226EX01   A0A336MM67   A0A1A9X7Q0   A0A310SFP8   A0A182X7D4   A0A1B0AX17   E9G7X0   A0A1A9ZZD9   A0A0P6B6Q4   A0A1D2NGC4   A0A1B0FAE9   Q17AJ1   Q7PRN6   A0A0Q9WLC7   A0A182LDK5   Q9W4S0   A0A158NWR0   A0A0P5HCE5   A0A0P5C839   A0A1J1I9A8   K7J6L6   A0A1S4FAC8   Q8IRU1   A0A1V9XB45   B4I171   A0A0K2T2Z0   A0A0P5HQW6   T1ISA1   A0A210QQ71   K1P775   K1QJY2   A0A0L8HB76  

Pubmed

26354079    28756777    23537049    18362917    19820115    30249741    + More
21719571    24845553    20798317    28648823    24508170    21282665    20566863    24438588    25315136    15632085    17994087    26108605    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26483478    17550304    25244985    24495485    21292972    27289101    17510324    12364791    20966253    26109357    26109356    21347285    20075255    28327890    28812685    22992520   

EMBL

ODYU01001388    SOQ37504.1    KQ460971    KPJ10142.1    NWSH01003679    PCG65946.1    + More
KZ149896    PZC78735.1    KQ459590    KPI97171.1    APGK01027141    APGK01027142    KB740648    KB630489    KB631709    KB632148    ENN79789.1    ERL83626.1    ERL85521.1    ERL89103.1    KQ971319    EFA00300.1    QOIP01000008    RLU19205.1    GL888093    EGI67632.1    KK853359    KDR08170.1    JR049473    AEY60975.1    KQ435732    KOX77450.1    GL445914    EFN88823.1    KQ434938    KZC12143.1    GL439840    EFN66716.1    NNAY01002512    OXU21159.1    NEVH01022635    PNF18602.1    KQ980322    KYN16660.1    KQ981617    KYN39261.1    KQ977444    KYN02689.1    KQ982080    KYQ60118.1    KK107064    EZA60823.1    GL762454    EFZ21446.1    ACPB03006720    KQ976732    KYM76174.1    DS235281    EEB14337.1    KK856124    PTY24946.1    LBMM01000247    KMR03124.1    KZ288230    PBC31586.1    KQ414669    KOC64513.1    ATLV01015153    KE525003    KFB40140.1    APCN01001081    AXCM01002848    AXCN02001363    CH379063    EAL32715.3    OUUW01000011    SPP86856.1    CH940651    EDW65675.1    CH916370    EDV99530.1    JRES01000902    KNC27425.1    AE014298    ACL82883.1    CH964239    EDW82738.1    CH954180    EDV45728.1    JXUM01087655    KQ563649    KXJ73558.1    CM000162    EDX01282.1    CM000366    EDX17000.1    CH902640    EDV38269.1    GAMC01005628    JAC00928.1    CH933815    EDW07990.1    CP012528    ALC48517.1    GDIP01203826    LRGB01002076    JAJ19576.1    KZS09409.1    GDIQ01006874    JAN87863.1    LNIX01000001    OXA62069.1    UFQT01001722    SSX31522.1    KQ761738    OAD57131.1    JXJN01004969    GL732534    EFX84589.1    GDIP01018964    JAM84751.1    LJIJ01000048    ODN04311.1    CCAG010008637    CCAG010008638    CH477333    EAT43303.1    AAAB01008847    EAA06912.6    KRF82337.1    BT001443    AAN09096.1    AAN71198.1    ADTU01028380    GDIQ01229585    JAK22140.1    GDIP01174114    JAJ49288.1    CVRI01000044    CRK96853.1    AAZX01009864    AAF45873.3    MNPL01016780    OQR70656.1    CH480819    EDW53252.1    HACA01002586    CDW19947.1    GDIQ01226226    JAK25499.1    JH431429    NEDP02002420    OWF50883.1    JH818927    EKC19482.1    JH816138    EKC34058.1    KQ418612    KOF86531.1   

Proteomes

UP000053240    UP000218220    UP000053268    UP000019118    UP000030742    UP000007266    + More
UP000279307    UP000007755    UP000027135    UP000053105    UP000005203    UP000008237    UP000076502    UP000000311    UP000215335    UP000235965    UP000078492    UP000078541    UP000078542    UP000075809    UP000053097    UP000015103    UP000078540    UP000009046    UP000192223    UP000036403    UP000242457    UP000053825    UP000030765    UP000075900    UP000095301    UP000075903    UP000075902    UP000075840    UP000075883    UP000075886    UP000075920    UP000075881    UP000001819    UP000268350    UP000078200    UP000069272    UP000008792    UP000001070    UP000037069    UP000000803    UP000007798    UP000008711    UP000069940    UP000249989    UP000002282    UP000076408    UP000000304    UP000095300    UP000007801    UP000075884    UP000091820    UP000192221    UP000009192    UP000092553    UP000076858    UP000075880    UP000198287    UP000092443    UP000076407    UP000092460    UP000000305    UP000092445    UP000094527    UP000092444    UP000008820    UP000007062    UP000075882    UP000005205    UP000183832    UP000002358    UP000192247    UP000001292    UP000242188    UP000005408    UP000053454   

PRIDE

B7Z122    Q9W4S0    Q8IRU1   

Pfam

PF00209   SNF        + More
PF15011   CK2S
PF07645   EGF_CA
PF00008   EGF
PF00147   Fibrinogen_C

Interpro

IPR037272   SNS_sf        + More
IPR000175   Na/ntran_symport       
IPR002438   Neutral_aa_SLC6       
IPR029159   CK2S       
IPR036322   WD40_repeat_dom_sf       
IPR002181   Fibrinogen_a/b/g_C_dom       
IPR001881   EGF-like_Ca-bd_dom       
IPR036056   Fibrinogen-like_C       
IPR013032   EGF-like_CS       
IPR018097   EGF_Ca-bd_CS       
IPR000742   EGF-like_dom       
IPR000152   EGF-type_Asp/Asn_hydroxyl_site       

SUPFAM

SSF161070   SSF161070        + More
SSF50978   SSF50978       
SSF56496   SSF56496       

CDD

cd00087  FReD

ProteinModelPortal

A0A2H1VB97   A0A0N1PI46   A0A2A4J2I1   A0A2W1BYK9   A0A194PUT7   N6TH77   + More
D6WF78   A0A3L8DFG3   F4WDU6   A0A067QK51   V9IIT8   A0A0M9A559   A0A087ZZD7   E2B634   A0A154PJZ4   E2AIM7   A0A232ES14   A0A2J7PQJ5   A0A195DUT1   A0A195FFX7   A0A195CRF3   A0A151XIK1   A0A026WYB0   E9IDL1   T1I2Z2   A0A195AW29   E0VLT1   A0A2R7WZI5   A0A1W4XVE7   A0A0J7L8S8   A0A2A3EK71   A0A0L7R0Y6   A0A084VQ96   A0A182RKR6   A0A1I8MX21   A0A182V1D1   A0A182TEQ0   A0A182IA05   A0A182M6Y4   A0A182Q4H7   A0A182W5V4   A0A182KAF6   Q29ID8   A0A3B0KLZ4   A0A1A9ULI3   A0A182FK95   B4M1X1   B4JIW6   A0A0L0C570   B7Z122   B4ND29   B3NSP8   A0A182GTQ1   B4Q0J8   A0A182YCR3   B4R458   A0A1I8P2J0   B3N065   W8BPP3   A0A182N0X1   A0A1A9W244   A0A1W4V8C1   B4L8L5   A0A0M4EXL4   A0A0P5AI26   A0A0P6JIK8   A0A182IQ63   A0A226EX01   A0A336MM67   A0A1A9X7Q0   A0A310SFP8   A0A182X7D4   A0A1B0AX17   E9G7X0   A0A1A9ZZD9   A0A0P6B6Q4   A0A1D2NGC4   A0A1B0FAE9   Q17AJ1   Q7PRN6   A0A0Q9WLC7   A0A182LDK5   Q9W4S0   A0A158NWR0   A0A0P5HCE5   A0A0P5C839   A0A1J1I9A8   K7J6L6   A0A1S4FAC8   Q8IRU1   A0A1V9XB45   B4I171   A0A0K2T2Z0   A0A0P5HQW6   T1ISA1   A0A210QQ71   K1P775   K1QJY2   A0A0L8HB76  

PDB

6AWQ     E-value=7.05615e-93,     Score=871

KEGG

101737854    K05048 solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/

GO

GO:0016021   GO:0005328   GO:0005887   GO:0005886   GO:0015293   GO:0006836   GO:0005326   GO:0005509   GO:0016020   GO:0043412   GO:0015074   GO:0015923   GO:0005634   GO:0006260  

PANTHER

PTHR11616  

Length:

575

Number of predicted TMHs:

10

Exp number of AAs in TMHs:

218.55792

Exp number, first 60 AAs:

0

Total prob of N-in:

0.98049

inside

1  -  98

TMhelix

99  -  121

outside

122  -  130

TMhelix

131  -  153

inside

154  -  172

TMhelix

173  -  195

outside

196  -  257

TMhelix

258  -  280

inside

281  -  284

TMhelix

285  -  307

outside

308  -  330

TMhelix

331  -  353

inside

354  -  365

TMhelix

366  -  388

outside

389  -  480

TMhelix

481  -  503

inside

504  -  523

TMhelix

524  -  546

outside

547  -  555

TMhelix

556  -  573

inside

574  -  575

 

 

Pi

233.626866

Theta

186.984902

Tajima's D

1.105975

CLR

0.569742

CSRT

0.684065796710165

Interpretation

Uncertain