Gene

KWMTBOMO06406  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011939

Annotation

putative_bisphosphate_nucleotidase_[Danaus_plexippus]

Location

Bomo_Chr11(+):6497151-6499044      View in EpiBrowser

Full name

Putative inositol monophosphatase 3      

Alternative Name

Inositol-1(or 4)-monophosphatase 3
Myo-inositol monophosphatase A3

Location in the cell

Cytoplasmic   Reliability : 1.268 Extracellular   Reliability : 1.527

CDS

ATGAATCTCGGTGGGACATTACGAATTAACAAGTTCGCTTGTTTCACATTGGCTTTTGTATTATTTCTGATAATATACTGGCGATCCGGAACATCTAGCTATCCTACAGAGAAGAGTCACTTAGTTAATTTAAAGAGTTTATTAAAAGCCGCTATCTTAGCCGCCGAAGGAGGAGGCAAGAAAGTATTGGACGGAAAAAATCATATTTTGAATGTTAAGAGTAAGGGTAAAACTTTGGAAGGCGCCAACGACCCTGTAACTGATGTTGATTATGCATCGCATTGCGCTATGTATTATGGTTTAAAACACACTTTTAATAATATCGATGTGGTCTCTGAGGAGCATTCGAAGAGTGATAGTAGCTGCGAGGAGGTGCCTGCTTTCGACTTGGAGCCCGACATCCCCGGGAATCTGAACATTGAGCAAATGCTTGATGAGCTTGTGCTTGCTAAAGATGTTGTTGTTTGGATCGACCCATTAGATGCCACCCAGGAGTATACAGAGAAACTGTACCAATATGTTACAACAATGGTATGTGTTGCTATAAGAGGAGTGCCAATAATAGGAGTCATCCATTATCCATTCACACAGCAAACATATTGGGCATGGTATACTAAGAAAACATCAGCTAATATGCCACTTGTACCGCATAAAGAAGAAAACAGGGAACATCCTAGAGTGGTAATTTCTCGATCACATCCTGGAAAAGTTGCCACTGTAGCCAAAAGTGCTTTTGGAGACAAGTCCAATGTTTCCAAAGCTGCTGGAGCAGGATTCAAGCAGATGGCCATGTTGCAGTGA

Protein

MNLGGTLRINKFACFTLAFVLFLIIYWRSGTSSYPTEKSHLVNLKSLLKAAILAAEGGGKKVLDGKNHILNVKSKGKTLEGANDPVTDVDYASHCAMYYGLKHTFNNIDVVSEEHSKSDSSCEEVPAFDLEPDIPGNLNIEQMLDELVLAKDVVVWIDPLDATQEYTEKLYQYVTTMVCVAIRGVPIIGVIHYPFTQQTYWAWYTKKTSANMPLVPHKEENREHPRVVISRSHPGKVATVAKSAFGDKSNVSKAAGAGFKQMAMLQ

Catalytic Activity

a myo-inositol phosphate + H2O = myo-inositol + phosphate

Cofactor

Mg(2+)

Similarity

Belongs to the inositol monophosphatase superfamily.

Keywords

Complete proteome   Hydrolase   Magnesium   Membrane   Metal-binding   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Putative inositol monophosphatase 3

Uniprot

H9JQY3   A0A2H1VVT3   A0A2W1BUF5   A0A2A4J047   A0A3S2NSG7   A0A212FDZ6   + More
A0A0L7KPB0   A0A0N1PHB7   A0A194PUS7   Q17CJ1   A0A1S4F800   A0A023ERE4   B0W8L8   A0A1L8DM98   A0A1Q3FCW4   A0A1B0GGR1   A0A3Q0J0B0   A0A1B0DDA0   A0A182SQD0   A0A182YGF7   A0A182RNH2   A0A0A9WGF4   A0A182VR88   A0A182VGG8   A0A182UD35   A0A182HKR5   A0A182X9T3   A0A182L928   A0A1J1I3D2   A0A2M4AVM2   A0A2M4AW41   A0A0V0G7I0   Q7PXG6   A0A182Q4E6   A0A182N5D2   A0A182JPB6   A0A023F0T6   A0A182P2H2   A0A182F794   A0A2M4BSV3   W5JIG5   A0A2M4BT85   A0A336KC29   E0VYW2   A0A2J7PCX7   A0A224XS35   W8BXB6   A0A182IUH4   A0A084WQT5   A0A2B4RX26   A0A1Y1KLA4   A0A0P4WBY4   A0A0P4WKP8   A0A3M6TB15   A0A182GPE3   T1I5R4   U5ESQ0   A0A1I8N884   T1P9S2   A0A2G8KJE7   A0A1I8NMX7   A0A1B6L012   A0A182MC89   A0A0A1X8R0   A0A069DT15   A0A034VSD0   A0A0K8VC75   A0A293MA12   A0A293LFI8   A0A2R7W4F9   D3TM44   Q29JH0   A0A1A9VS92   A0A2P8XM43   A0A1A9YA74   A0A3F2Z4P6   T2M4I0   A0A1B6GM15   A0A1Z5LAN6   B3NWQ7   B4Q233   A0A1W4VK88   B4M7C2   M9PH13   Q9VYF2   A0A1A9WVA1   A0A154P0E1   A0A087UY50   B4IGQ1   A0A067R5J1   D6WH25   A0A3B0J6V8   W4XS15   A0A310SM18   B4JJ71   A0A2P6K4G3   A0A2T7NNW6   A0A0L7QXB1   A0A0M9AE81   B7PTD3  

EC Number

3.1.3.25

Pubmed

19121390    28756777    22118469    26227816    26354079    17510324    + More
24945155    25244985    25401762    26823975    20966253    12364791    14747013    17210077    25474469    20920257    23761445    20566863    24495485    24438588    28004739    30382153    26483478    25315136    29023486    25830018    26334808    25348373    20353571    15632085    29403074    24065732    28528879    17994087    17550304    18057021    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    12537569    24845553    18362917    19820115   

EMBL

BABH01028565    ODYU01004580    SOQ44602.1    KZ149897    PZC78678.1    NWSH01004140    + More
PCG65445.1    RSAL01000104    RVE47377.1    AGBW02008998    OWR51907.1    JTDY01007781    KOB64945.1    KQ460210    KPJ16584.1    KQ459590    KPI97161.1    CH477308    EAT44030.1    GAPW01002359    JAC11239.1    DS231859    EDS39068.1    GFDF01006600    JAV07484.1    GFDL01009717    JAV25328.1    AJWK01000607    AJVK01031805    GBHO01040945    GBHO01037123    GBRD01000688    GDHC01019060    GDHC01007824    JAG02659.1    JAG06481.1    JAG65133.1    JAP99568.1    JAQ10805.1    APCN01000860    CVRI01000038    CRK94100.1    GGFK01011518    MBW44839.1    GGFK01011601    MBW44922.1    GECL01002118    JAP04006.1    AAAB01008987    EAA01450.4    AXCN02001179    GBBI01003622    JAC15090.1    GGFJ01006999    MBW56140.1    ADMH02001070    ETN64182.1    GGFJ01007000    MBW56141.1    UFQS01000188    UFQT01000188    SSX00985.1    SSX21365.1    DS235848    EEB18568.1    NEVH01026401    PNF14189.1    GFTR01005176    JAW11250.1    GAMC01000605    JAC05951.1    ATLV01025724    KE525398    KFB52579.1    LSMT01000299    PFX20878.1    GEZM01084874    GEZM01084872    GEZM01084871    GEZM01084870    JAV60445.1    GDRN01082559    JAI61811.1    GDRN01082560    JAI61810.1    RCHS01003977    RMX38587.1    JXUM01078327    JXUM01078328    JXUM01078329    JXUM01078330    JXUM01078331    JXUM01078332    JXUM01078333    KQ563059    KXJ74557.1    ACPB03006895    GANO01002256    JAB57615.1    KA645501    AFP60130.1    MRZV01000539    PIK48123.1    GEBQ01022935    JAT17042.1    AXCM01008432    GBXI01006603    JAD07689.1    GBGD01002082    JAC86807.1    GAKP01014258    GAKP01014257    JAC44695.1    GDHF01015836    JAI36478.1    GFWV01011241    MAA35970.1    GFWV01001908    MAA26638.1    KK854314    PTY14552.1    CCAG010020716    EZ422496    ADD18772.1    CH379063    PYGN01001739    PSN33073.1    JXJN01022690    HAAD01000734    CDG66966.1    GECZ01006283    JAS63486.1    GFJQ02002508    JAW04462.1    CH954180    EDV47219.1    CM000162    EDX01554.1    CH940653    EDW62689.2    KRF80762.1    AE014298    AGB95353.1    AHN59667.1    BT004861    KQ434783    KZC04824.1    KK122233    KFM82289.1    CH480836    EDW49001.1    KK852729    KDR17547.1    KQ971321    EFA00621.1    OUUW01000003    SPP77777.1    AAGJ04023973    KQ759893    OAD62071.1    CH916370    EDV99623.1    MWRG01030100    PRD21219.1    PZQS01000010    PVD22870.1    KQ414705    KOC63245.1    KQ435687    KOX81349.1    ABJB010610209    ABJB010735492    ABJB010778331    DS785108    EEC09855.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000007151    UP000037510    UP000053240    + More
UP000053268    UP000008820    UP000002320    UP000092461    UP000079169    UP000092462    UP000075901    UP000076408    UP000075900    UP000075920    UP000075903    UP000075902    UP000075840    UP000076407    UP000075882    UP000183832    UP000007062    UP000075886    UP000075884    UP000075881    UP000075885    UP000069272    UP000000673    UP000009046    UP000235965    UP000075880    UP000030765    UP000225706    UP000275408    UP000069940    UP000249989    UP000015103    UP000095301    UP000230750    UP000095300    UP000075883    UP000092444    UP000001819    UP000078200    UP000245037    UP000092443    UP000092460    UP000008711    UP000002282    UP000192221    UP000008792    UP000000803    UP000091820    UP000076502    UP000054359    UP000001292    UP000027135    UP000007266    UP000268350    UP000007110    UP000001070    UP000245119    UP000053825    UP000053105    UP000001555   

PRIDE

H9JQY3    M9PH13    Q9VYF2   

Pfam

PF00459   Inositol_P        + More
PF00179   UQ_con

Interpro

IPR000760   Inositol_monophosphatase-like        + More
IPR020550   Inositol_monophosphatase_CS       
IPR000608   UBQ-conjugat_E2       
IPR016135   UBQ-conjugating_enzyme/RWD       

SUPFAM

SSF54495   SSF54495       

Gene 3D

3.10.110.10    

CDD

cd00195  UBCc

ProteinModelPortal

H9JQY3   A0A2H1VVT3   A0A2W1BUF5   A0A2A4J047   A0A3S2NSG7   A0A212FDZ6   + More
A0A0L7KPB0   A0A0N1PHB7   A0A194PUS7   Q17CJ1   A0A1S4F800   A0A023ERE4   B0W8L8   A0A1L8DM98   A0A1Q3FCW4   A0A1B0GGR1   A0A3Q0J0B0   A0A1B0DDA0   A0A182SQD0   A0A182YGF7   A0A182RNH2   A0A0A9WGF4   A0A182VR88   A0A182VGG8   A0A182UD35   A0A182HKR5   A0A182X9T3   A0A182L928   A0A1J1I3D2   A0A2M4AVM2   A0A2M4AW41   A0A0V0G7I0   Q7PXG6   A0A182Q4E6   A0A182N5D2   A0A182JPB6   A0A023F0T6   A0A182P2H2   A0A182F794   A0A2M4BSV3   W5JIG5   A0A2M4BT85   A0A336KC29   E0VYW2   A0A2J7PCX7   A0A224XS35   W8BXB6   A0A182IUH4   A0A084WQT5   A0A2B4RX26   A0A1Y1KLA4   A0A0P4WBY4   A0A0P4WKP8   A0A3M6TB15   A0A182GPE3   T1I5R4   U5ESQ0   A0A1I8N884   T1P9S2   A0A2G8KJE7   A0A1I8NMX7   A0A1B6L012   A0A182MC89   A0A0A1X8R0   A0A069DT15   A0A034VSD0   A0A0K8VC75   A0A293MA12   A0A293LFI8   A0A2R7W4F9   D3TM44   Q29JH0   A0A1A9VS92   A0A2P8XM43   A0A1A9YA74   A0A3F2Z4P6   T2M4I0   A0A1B6GM15   A0A1Z5LAN6   B3NWQ7   B4Q233   A0A1W4VK88   B4M7C2   M9PH13   Q9VYF2   A0A1A9WVA1   A0A154P0E1   A0A087UY50   B4IGQ1   A0A067R5J1   D6WH25   A0A3B0J6V8   W4XS15   A0A310SM18   B4JJ71   A0A2P6K4G3   A0A2T7NNW6   A0A0L7QXB1   A0A0M9AE81   B7PTD3  

PDB

1JP4     E-value=1.40897e-08,     Score=140

KEGG

101743017    K15759 inositol monophosphatase 3 [EC:3.1.3.25 3.1.3.7] | (RefSeq) putative inositol monophosphatase

PATHWAY

00562    Inositol phosphate metabolism - Bombyx mori (domestic silkworm)
00920    Sulfur metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04070    Phosphatidylinositol signaling system - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0046854   GO:0008254   GO:0052833   GO:0046872   GO:0006021   GO:0005737   GO:0006661   GO:0007165   GO:0052832   GO:0006796   GO:0008934   GO:0004441   GO:0016311   GO:0012505   GO:0030170   GO:0003824   GO:0051536   GO:0016740   GO:0043412   GO:0015074   GO:0015923   GO:0005634   GO:0006260  

Subcellular location

Membrane  

Length:

266

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

34.16291

Exp number, first 60 AAs:

20.18639

Total prob of N-in:

0.90129

POSSIBLE N-term signal

sequence

inside

1  -  11

TMhelix

12  -  31

outside

32  -  266

 

 

Pi

137.306922

Theta

149.599124

Tajima's D

-0.473165

CLR

0.318318

CSRT

0.249137543122844

Interpretation

Uncertain