Gene

KWMTBOMO06400

Pre Gene Modal

BGIBMGA011935

Annotation

PREDICTED:_protein_trapped_in_endoderm-1_isoform_X2_[Papilio_xuthus]

Location

Bomo_Chr11(+):6381101-6455587      View in EpiBrowser

Full name

Protein trapped in endoderm-1      

Location in the cell

PlasmaMembrane   Reliability : 4.996

CDS

ATGTCTTCTATCGATAAAATGTATAATTTTACGTTGAGCGACGCGCAAAATGGGACATTTTATCCCACTGAGGCCACGATCTTGGCCGCTGTCTGTGCGAGCGTATTCAGCGTTGTTGGAGTAGTTGGTAACTTAGTAACCGCTGTAGCTCTACTCATGCATCCGAAGCTAAGAGGCCACGTGACCACAATGTTCGTGCTCTCCCTCTGCCTCTCCGATCTACTCTTCTGCGCCATCAACCTGCCTCTAACCGCCAATAGGTTCATCAAGCAACACTGGAGTCTCGGGCCTCAGCTGTGTCAACTTTTCGCGTTCATTTTTTATGGAAATGAAGCCGTGTCACTATTGTCCATGGTGGCTATCACTATTAACAGATACACATTGATAGCATACTACGACATGTACGCGCAAATCTATACGACCACGAAGATATGGATACAATTGCTCCTCATCTGGATCGTGTCTTTCGGATTCATGATTCCCCCCCTGCTCGGCATCTGGGGTCAACTAGGGTTGGAGAAGAACACGTTTTCGTGCACGATATTACCGAAGAACGGGCAGTCGCCGAAAAAAGCGTTGTTCGTTTTCGGCTTCGCGTTGCCCTGCGTCGCGATCATCGTCTCGTACTCGTGCATCTATTGGCGCGTCAGACAGAGCAAACGGAAACTTGAAGGACACGGTAAACTCAGCGGCCAGACTGCGAAAGAGAAAGAAGAAGACTCTAGACTGACGAGGCTGATGCTGACCATCTTCGTGTGCTTCCTCGCCTGCTTCCTGCCGCTGATGATCATGAACGTGGCCGACGACGACATCACGTACCCCTGGCTCCACATCATCGCCTCGATCCTGGCGTGGGCGTCCAGCGTGGTCAACCCGCTGATCTACGCGGCCACCAACAGGCAGTACCGGGCCGCCTACGCCAACCTCCTCAAGTTCTGCAAGCTCAGCCCCGCCTCCCGAAGAACGACGTACGGCAGTCGAACCATGGCGCAGTCCTCCAACTGA

Protein

MSSIDKMYNFTLSDAQNGTFYPTEATILAAVCASVFSVVGVVGNLVTAVALLMHPKLRGHVTTMFVLSLCLSDLLFCAINLPLTANRFIKQHWSLGPQLCQLFAFIFYGNEAVSLLSMVAITINRYTLIAYYDMYAQIYTTTKIWIQLLLIWIVSFGFMIPPLLGIWGQLGLEKNTFSCTILPKNGQSPKKALFVFGFALPCVAIIVSYSCIYWRVRQSKRKLEGHGKLSGQTAKEKEEDSRLTRLMLTIFVCFLACFLPLMIMNVADDDITYPWLHIIASILAWASSVVNPLIYAATNRQYRAAYANLLKFCKLSPASRRTTYGSRTMAQSSN

Description

Essential for the first active step of germ cell migration: transepithelial migration of germ cells through the posterior midgut (PMG) epithelium.

Miscellaneous

Overexpression of the Tre1 gene restores the taste sensitivity to trehalose in a Tre1 mutant (PubMed:10884225). This experiment cannot be explained given that other authors demonstrate that trehalose sensitivity maps to the adjacent gene, Gr5a (PubMed:14691551).

Similarity

Belongs to the G-protein coupled receptor 1 family.

Keywords

Cell membrane   Complete proteome   G-protein coupled receptor   Glycoprotein   Membrane   Phosphoprotein   Polymorphism   Receptor   Reference proteome   Transducer   Transmembrane   Transmembrane helix  

Feature

chain  Protein trapped in endoderm-1

Uniprot

A0A2W1C3E6   A0A194PUS2   A0A3S2PCC8   A0A0N0PDU5   A0A140B7Z4   A0A212FDT6   + More
A0A3Q8HDG4   S4NXM5   A0A0L7LL27   D6W7A8   A0A067R423   N6T220   A0A310S3H6   A0A2P8ZH70   A0A088AH57   A0A1Y1L9X6   E9IEH8   A0A195BMR5   A0A158P001   M3UZE9   A0A0E3U2L3   A0A1B0G8C7   A0A1A9Z5T9   A0A195E0Z0   A0A1A9VBM4   A0A0T6B087   A0A195CQI6   A0A1A9XXS6   A0A1B0APR5   A0A151X3T0   F4X3L3   E2ACX8   A0A195F1W8   A0A026VWC8   A0A3L8DVX9   A0A154NYY3   A0A0C9RMU3   A0A0L7RH13   A0A0M8ZZ76   E2BB10   A0A1I8PP66   W8BTX2   A0A232ER08   K7IYK6   A0A0A1XHY2   A0A1I8MNM5   A0A0K8WGU9   A0A0M3QZR8   E9HQ17   B4I0L7   A0A3B0KW52   M9NGQ9   Q9NDM2   A0A2P2IDF3   D2CFN9   C6SUV0   B4L639   A0A0P6EHZ1   B3NV70   B4PZC6   A0A0P6I2T5   A0A1W4VFR0   B4R509   A0A0P6B268   A0A0P6GGD5   X2JIG6   B3MRX8   A0A0K2TB03   A0A0K2TAV5   A0A0P5LQ63   A0A1Q3EUA3   B0W7R2   A0A0N8D974   B4MSG7   A0A1B0CGF8   A0A1B0DPT3   B4M809   Q29I11   B4H4G1   A0A0Q9W6D3   B4JKJ2   T1DIC6   A0A0P5SSI3   A0A1I8PP95   A0A087U3N9   Q17KN3   A0A1D2NGM4   A0A2P8XU17   A0A1W4WBL3   A0A061QFZ2   A0A1W4WBM3   A0A3S3P8F5  

Pubmed

28756777    26354079    26930056    22118469    23622113    26227816    + More
18362917    19820115    24845553    23537049    29403074    28004739    21282665    21347285    23517120    25856077    21719571    20798317    24508170    30249741    24495485    28648823    20075255    25830018    25315136    21292972    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    10884225    11566105    12537569    14691551    18327897    17550304    18057021    15632085    24330624    17510324    27289101   

EMBL

KZ149897    PZC78683.1    KQ459590    KPI97156.1    RSAL01000104    RVE47371.1    + More
KQ460210    KPJ16588.1    KT860048    ALS03936.1    AGBW02008998    OWR51901.1    MF625599    AXY83426.1    GAIX01014130    JAA78430.1    JTDY01000680    KOB76248.1    KQ971307    EFA11575.1    KK852996    KDR12697.1    APGK01047123    APGK01047124    KB741077    KB632384    ENN74144.1    ERL94278.1    GGOB01000040    MCH29436.1    PYGN01000058    PSN55846.1    GEZM01063405    JAV69110.1    GL762593    EFZ21025.1    KQ976440    KYM86576.1    ADTU01005183    GACR01000044    JAA74417.1    KM251701    AKC58582.1    CCAG010000239    KQ979955    KYN18544.1    LJIG01016349    KRT80867.1    KQ977394    KYN03008.1    JXJN01001549    JXJN01001550    KQ982557    KYQ55086.1    GL888624    EGI58810.1    GL438602    EFN68708.1    KQ981856    KYN34570.1    KK107929    EZA47109.1    QOIP01000003    RLU24614.1    KQ434775    KZC04080.1    GBYB01009685    JAG79452.1    KQ414591    KOC70267.1    KQ435794    KOX74110.1    GL446901    EFN87101.1    GAMC01003914    GAMC01003913    JAC02643.1    NNAY01002687    OXU20771.1    GBXI01003767    JAD10525.1    GDHF01002214    JAI50100.1    CP012528    ALC49893.1    GL732713    EFX66166.1    CH480819    EDW53048.1    OUUW01000025    SPP89631.1    AE014298    AFH07248.1    AB034204    AB042625    AB066613    AB066614    AB066615    AB066616    AB066617    AB066618    AY070980    IACF01006456    LAB72039.1    DQ666846    ABH01174.1    BT088942    ACT76688.1    CH933812    EDW05835.1    GDIQ01076346    LRGB01000359    JAN18391.1    KZS19551.1    CH954180    EDV45918.2    CM000162    EDX01093.1    GDIQ01011374    JAN83363.1    CM000366    EDX17158.1    GDIP01021067    JAM82648.1    GDIQ01053579    JAN41158.1    AHN59372.1    CH902622    EDV34533.1    HACA01005832    CDW23193.1    HACA01005833    CDW23194.1    GDIQ01166778    JAK84947.1    GFDL01016154    JAV18891.1    DS231855    EDS38206.1    GDIP01056455    JAM47260.1    CH963851    EDW75056.1    AJWK01011081    AJVK01008240    AJVK01008241    CH940653    EDW62285.1    KRF80538.1    CH379064    EAL31595.2    CH479209    EDW32712.1    KRF80537.1    CH916370    EDW00095.1    GALA01001001    JAA93851.1    GDIP01135902    JAL67812.1    KK118013    KFM71978.1    CH477222    EAT47271.2    LJIJ01000044    ODN04410.1    PYGN01001348    PSN35490.1    GBFC01000021    JAC59317.1    NCKU01006631    RWS03304.1   

Proteomes

UP000053268    UP000283053    UP000053240    UP000007151    UP000037510    UP000007266    + More
UP000027135    UP000019118    UP000030742    UP000245037    UP000005203    UP000078540    UP000005205    UP000092444    UP000092445    UP000078492    UP000078200    UP000078542    UP000092443    UP000092460    UP000075809    UP000007755    UP000000311    UP000078541    UP000053097    UP000279307    UP000076502    UP000053825    UP000053105    UP000008237    UP000095300    UP000215335    UP000002358    UP000095301    UP000092553    UP000000305    UP000001292    UP000268350    UP000000803    UP000009192    UP000076858    UP000008711    UP000002282    UP000192221    UP000000304    UP000007801    UP000002320    UP000007798    UP000092461    UP000092462    UP000008792    UP000001819    UP000008744    UP000001070    UP000054359    UP000008820    UP000094527    UP000192223    UP000285301   

PRIDE

Q9NDM2    D2CFN9    X2JIG6   

Pfam

PF00001   7tm_1

Interpro

IPR000276   GPCR_Rhodpsn        + More
IPR017452   GPCR_Rhodpsn_7TM       
IPR033116   TRYPSIN_SER       

ProteinModelPortal

A0A2W1C3E6   A0A194PUS2   A0A3S2PCC8   A0A0N0PDU5   A0A140B7Z4   A0A212FDT6   + More
A0A3Q8HDG4   S4NXM5   A0A0L7LL27   D6W7A8   A0A067R423   N6T220   A0A310S3H6   A0A2P8ZH70   A0A088AH57   A0A1Y1L9X6   E9IEH8   A0A195BMR5   A0A158P001   M3UZE9   A0A0E3U2L3   A0A1B0G8C7   A0A1A9Z5T9   A0A195E0Z0   A0A1A9VBM4   A0A0T6B087   A0A195CQI6   A0A1A9XXS6   A0A1B0APR5   A0A151X3T0   F4X3L3   E2ACX8   A0A195F1W8   A0A026VWC8   A0A3L8DVX9   A0A154NYY3   A0A0C9RMU3   A0A0L7RH13   A0A0M8ZZ76   E2BB10   A0A1I8PP66   W8BTX2   A0A232ER08   K7IYK6   A0A0A1XHY2   A0A1I8MNM5   A0A0K8WGU9   A0A0M3QZR8   E9HQ17   B4I0L7   A0A3B0KW52   M9NGQ9   Q9NDM2   A0A2P2IDF3   D2CFN9   C6SUV0   B4L639   A0A0P6EHZ1   B3NV70   B4PZC6   A0A0P6I2T5   A0A1W4VFR0   B4R509   A0A0P6B268   A0A0P6GGD5   X2JIG6   B3MRX8   A0A0K2TB03   A0A0K2TAV5   A0A0P5LQ63   A0A1Q3EUA3   B0W7R2   A0A0N8D974   B4MSG7   A0A1B0CGF8   A0A1B0DPT3   B4M809   Q29I11   B4H4G1   A0A0Q9W6D3   B4JKJ2   T1DIC6   A0A0P5SSI3   A0A1I8PP95   A0A087U3N9   Q17KN3   A0A1D2NGM4   A0A2P8XU17   A0A1W4WBL3   A0A061QFZ2   A0A1W4WBM3   A0A3S3P8F5  

PDB

5DHH     E-value=2.36653e-14,     Score=191

KEGG

101743722    K22873 protein trapped in endoderm-1 | (RefSeq) protein trapped in endoderm-1

GO

GO:0016021   GO:0004930   GO:0008502   GO:0005886   GO:0035234   GO:0005938   GO:0007281   GO:0007186   GO:0008354   GO:0007280   GO:0016787   GO:0051536   GO:0016740   GO:0043412   GO:0015074   GO:0015923   GO:0005634   GO:0006260  

Subcellular location

Cell membrane  

Length:

334

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

157.38341

Exp number, first 60 AAs:

24.29264

Total prob of N-in:

0.03335

POSSIBLE N-term signal

sequence

outside

1  -  29

TMhelix

30  -  52

inside

53  -  63

TMhelix

64  -  86

outside

87  -  100

TMhelix

101  -  123

inside

124  -  143

TMhelix

144  -  166

outside

167  -  191

TMhelix

192  -  214

inside

215  -  242

TMhelix

243  -  265

outside

266  -  274

TMhelix

275  -  297

inside

298  -  334

 

 

Pi

211.010353

Theta

155.889826

Tajima's D

1.122586

CLR

0.430838

CSRT

0.687515624218789

Interpretation

Uncertain