Gene

KWMTBOMO06398

Pre Gene Modal

BGIBMGA011967

Annotation

PREDICTED:_xylose_isomerase-like_[Bombyx_mori]

Location

Bomo_Chr11(-):6364551-6370780      View in EpiBrowser

Full name

Xylose isomerase      

Location in the cell

Nuclear   Reliability : 2.678

CDS

ATGTCATCGTACAGCCAGCCCGGAGCCAAACGACAGAAACTAAGGACTGAGCATGTCGATTACTTTCAAGCTATAGACAAAATACAGTATAACAATATGGCGGCTGCGTCTGACACTGCAAGCTACAGATACTACAACAGCGCGGAGAGAATACATTCCAAAACCATGGAGGAGTGGCTTAAATACAGCGTGTCCTTTTCTGAATTTAGAAATAACGGGTCGGATGCGCACGGTCGGCCGACACTCTCCCGCCAGTGGGACGACAACACGGATTCCGTTGAAAACCACAAACGATGCGTGAAGGCCCTATTCGATTTCTGCGTTAAAACCGGCATTAAATACTGGACGGCTTTCGATTCAGATTTGATACCACACTCTGATAATATTGAAGAAAACAAAACGTATTTTGATGAAATGGTGGAATGTGTGCAGGAATGTTCGCAGAGGAGTCATGTCAAGTTATTATGGATAGCTCCTGATTTGCACTCGCATCCCAGATACACGTCAGGCGCCTTCACTAGCAATGACGCGGCAACATTCGCACACGCAGCGACGCAGATAAAGCGATGTCTAGAAATGTCACAGCGTATGAACGCGGAGTGCTTCTTGCTATGGCCTTACAGGGAGGGTTATGACAATGTGTACCACGCCGACGTGGGTAGAGAGATTAAATTGTTCGCGAAACTCATGAAAATCACAGCCGAGTATAAAGATAGATTGAATTACAGATGTCAACTATTAATGATGCCGTATTACAATTCTAATATGCACACAAACGACGGCTGTACGTACCACAGCTGGCAACACAGACAATGGCGCGAAACCGAAATGATAAATATGTACATGTGGGATGTGACCAGCTGTTTGTATTTCCTAAAACATTACAATTTAGATCGTTATTACAAAGTTTGTTCGCCGCCCGGACACCACATGTACATGGCTAATGTATACAACATGCTAGGAGGGGTGTTTGTTACGAATGCGGTCGATCAGTGCGATAGCAGGCGGCTCACACTCATGATGAAGTTGATTGTCGAACAGGGCACGCCGCTTCCCGGAGGTATCAACCTGAAGCTGTCGCCCCGCCGGGACGGCGACCTACGGGACTACGTCACGACATACGTTAAATACGTCGATGCCATGGCGAGGGCTCTACGATTCGCTTGCAGTTTGATTTCTGAACAGATACTGTCGAAACATTTGCAGCAACGGTACACGTCGTACTACAGCGGTTTCGGTTCCCGGCTCGTGAGCAGCGACGTCTCCATGGAGGAGTGTGAGGAATATCTGAAGAAGAGCCAGGGGTCCCGGGGGGATGCGCCGCCCTCCCAGGGCGAACACTTGGAGCTGACGCTACAGCGGTACCTGGATACTTGCGACCGAATCTGA

Protein

MSSYSQPGAKRQKLRTEHVDYFQAIDKIQYNNMAAASDTASYRYYNSAERIHSKTMEEWLKYSVSFSEFRNNGSDAHGRPTLSRQWDDNTDSVENHKRCVKALFDFCVKTGIKYWTAFDSDLIPHSDNIEENKTYFDEMVECVQECSQRSHVKLLWIAPDLHSHPRYTSGAFTSNDAATFAHAATQIKRCLEMSQRMNAECFLLWPYREGYDNVYHADVGREIKLFAKLMKITAEYKDRLNYRCQLLMMPYYNSNMHTNDGCTYHSWQHRQWRETEMINMYMWDVTSCLYFLKHYNLDRYYKVCSPPGHHMYMANVYNMLGGVFVTNAVDQCDSRRLTLMMKLIVEQGTPLPGGINLKLSPRRDGDLRDYVTTYVKYVDAMARALRFACSLISEQILSKHLQQRYTSYYSGFGSRLVSSDVSMEECEEYLKKSQGSRGDAPPSQGEHLELTLQRYLDTCDRI

Catalytic Activity

D-xylose = D-xylulose

Cofactor

Mg(2+)
Co(2+)
Mn(2+)

Subunit

Homotetramer.

Similarity

Belongs to the xylose isomerase family.

Keywords

Carbohydrate metabolism   Complete proteome   Cytoplasm   Isomerase   Magnesium   Metal-binding   Xylose metabolism   3D-structure   Cobalt   Reference proteome   Alternative splicing   Manganese  

Feature

chain  Xylose isomerase

Uniprot

A0A2H1VM01   A0A2A4JIW0   A0A212FDS1   A0A2W1BYK8   A0A1B6FCM8   A0A1B6JGC2   + More
A0A1B6KK25   A0A1B6E4W0   A0A1W4XIZ0   A0A1W4XUI3   A0A2P1JJ74   A0A323TN13   A0A0L8H1I1   A0A2P8Y7H6   A0A1S3J381   A0A3S1BHS4   A0A2P2I0B7   A0A1X7UQK7   H2ZCM4   A0A0P5W641   G3NKY4   A0A0P5Q4B3   V4AMB7   A0A0P4W3W2   A0A2D0PSZ9   A0A0P6IFG0   A0A1S3RX30   A0A1W2WBQ8   A0A3Q0JN07   A0A060XLD2   A0A2G8KQV6   G3NKW9   F6WBF5   A0A2D0PTW8   R7V2Y9   E9HNY5   K1QKM4   Q4T049   A7S4Q7   A0A385ZBK6   W7TK53   A0A3L7VVL8   A0A2R5GE83   A0A267E0P2   L8HKE1   A0A0P5HGF1   A0A267GIP4   A0A1I3NMJ5   A0A0C9RQC0   A0A3C1X2J0   A0A3L7UJA2   A0A3D3VYV7   D8T6N5   D8T6H4   A0A3L7N9T7   E4SGJ5   A0A0D6QWY3   A0A1Y1I2W2   A0A2K1KEJ1   A0A3B9D101   A0A1P8WEM4   A0A2E8FM44   A0A3R7Q3Y0   A0A352KY33   B9MPG8   A0A2U9AZT4   A0A3C1WG83   A0A2E7NK59   A9T7Y3   E4Q490   D9TIN9   A0A2P6TLE8   C3W9E8   A0A399ISP9   A0A2E7KCH8   A5ILR5   A0A3B8PKS3   A0A2R6DN25   Q8LFA4   A0A3M6TK47   A0A3B8LSF0   A0A0B5KKF0   B9K7G3   P45687   A0A1V4IEA1   E4QEE6   E4S4W9   G2PXL0   D2C8D9   A0A178PFM1   A0A101EPN0   G4FG56   Q9X1Z5   A0A329RCY7   A0A2H4G7K2   A0A2S2AYL7   A0A178UDJ9   Q9FKK7   A0A2E7RWH5  

EC Number

5.3.1.5

Pubmed

22118469    28756777    29403074    23254933    24755649    29023486    + More
12481130    15114417    21292972    22992520    15496914    17615350    30237825    23966634    30285851    23375108    30148503    21551031    21216991    24865297    18079367    29237241    28066393    29337314    20851897    29178410    28804480    12093376    30382153    7646024    27375578    26787827    23637642    10360571    27354520    9679202    27862469    14593172   

EMBL

ODYU01003295    SOQ41865.1    NWSH01001334    PCG71648.1    AGBW02008998    OWR51899.1    + More
KZ149897    PZC78684.1    GECZ01021814    JAS47955.1    GECU01009544    JAS98162.1    GEBQ01028174    JAT11803.1    GEDC01004326    JAS32972.1    MF385068    AVN99063.1    MDVM02000052    PYZ99338.1    KQ419574    KOF83108.1    PYGN01000834    PSN40216.1    RQTK01000079    RUS88570.1    IACF01001769    LAB67451.1    GDIP01090957    LRGB01002860    JAM12758.1    KZS05810.1    GDIQ01129288    JAL22438.1    KB201589    ESO95885.1    GDRN01074440    JAI63243.1    GDIQ01005301    JAN89436.1    FR905603    CDQ80418.1    MRZV01000421    PIK50386.1    EAAA01001738    AMQN01005197    KB295394    ELU13203.1    GL732700    EFX66553.1    JH815921    EKC29365.1    CAAE01011343    CAF93733.1    DS469579    EDO41326.1    MG787085    AYC35489.1    AZIL01002630    EWM21104.1    QWQN01000014    RLT22653.1    BEYU01000046    GBG28639.1    NIVC01002806    PAA55115.1    KB007811    ELR24876.1    GDIQ01227209    JAK24516.1    NIVC01000301    PAA85913.1    FOQD01000015    SFJ10150.1    GCHU01025304    JAG85619.1    DMRQ01000106    HAP06583.1    QWQG01000148    RLT06360.1    DQCF01000092    HCP11101.1    GL377682    EFJ07670.1    GL377681    EFJ07726.1    QWOO01000339    RLS28537.1    CP002330    ADQ46870.1    GCKF01041656    JAG95054.1    DF237061    GAQ82468.1    ABEU02000006    PNR52197.1    DLZC01000825    HAD61648.1    CP017641    APZ92523.1    PBSL01000057    MBQ18418.1    QCYY01002737    ROT67915.1    DNCU01000267    DNMF01000105    HAV32744.1    HBC60866.1    CP001393    CP026243    AWO97085.1    DMRM01000167    HAO99316.1    DLVF01000235    DPUZ01000615    PBOU01000020    HAA49669.1    HCK55305.1    MBO09796.1    DS545069    EDQ60517.1    CP002216    ADQ04052.1    CP002164    ADL41871.1    LHPG02000012    PRW45113.1    ACDB02000005    EEO34485.1    QXDJ01000002    RII35577.1    PBQK01000098    MBN70509.1    CP000702    DLVV01000222    DPBG01000017    HAB12184.1    HCC98964.1    PXQR01000022    PSP44228.1    AY084958    AAM61519.1    RCHS01003465    RMX41658.1    DLVH01000094    HAA60185.1    CP007633    AJG40818.1    CP000916    L38994    MZGT01000072    OPJ58283.1    CP002219    ADQ07765.1    CP002326    ADQ41469.1    CP003001    AEM73030.1    CP001839    ADA67225.1    LSKY01000013    OAO31240.1    LGFG01000123    KUK22608.1    CP004077    AGL50600.1    AE000512    MJFZ01001734    MJFZ01001379    MJFZ01000703    RAW21483.1    RAW22241.1    RAW22242.1    RAW25870.1    KX775441    APW83753.1    CP029329    AWK51127.1    LUHQ01000005    OAO91212.1    AB011482    CP002688    AY136469    BT006607    PBOJ01000049    MBO50608.1   

Proteomes

UP000218220    UP000007151    UP000192223    UP000247427    UP000053454    UP000245037    + More
UP000085678    UP000271974    UP000007879    UP000007875    UP000076858    UP000007635    UP000030746    UP000221080    UP000087266    UP000193380    UP000230750    UP000008144    UP000014760    UP000000305    UP000005408    UP000007303    UP000001593    UP000215902    UP000011083    UP000199518    UP000001514    UP000006835    UP000054558    UP000006727    UP000187735    UP000283509    UP000007723    UP000246464    UP000006889    UP000000347    UP000239899    UP000003415    UP000265930    UP000229979    UP000006558    UP000242659    UP000275408    UP000031770    UP000000445    UP000191056    UP000006890    UP000009256    UP000009257    UP000000940    UP000078243    UP000013901    UP000008183    UP000251314    UP000245215    UP000078284    UP000006548   

PRIDE

Q9X1Z5    Q9FKK7   

Pfam

PF04055   Radical_SAM        + More
PF01938   TRAM
PF00919   UPF0004
PF12722   Hid1
PF01261   AP_endonuc_2
PF01485   IBR

Interpro

IPR001998   Xylose_isomerase        + More
IPR036237   Xyl_isomerase-like_sf       
IPR038135   Methylthiotransferase_N_sf       
IPR020612   Methylthiotransferase_CS       
IPR007197   rSAM       
IPR006466   MiaB-like_B       
IPR002792   TRAM_dom       
IPR013848   Methylthiotransferase_N       
IPR023404   rSAM_horseshoe       
IPR006638   Elp3/MiaB/NifB       
IPR005839   Methylthiotransferase       
IPR013452   Xylose_isom_bac       
IPR026705   Hid-1/Ecm30       
IPR013022   Xyl_isomerase-like_TIM-brl       
IPR017907   Znf_RING_CS       
IPR002867   IBR_dom       

SUPFAM

SSF51658   SSF51658       

Gene 3D

3.40.50.12160     3.80.30.20    

ProteinModelPortal

A0A2H1VM01   A0A2A4JIW0   A0A212FDS1   A0A2W1BYK8   A0A1B6FCM8   A0A1B6JGC2   + More
A0A1B6KK25   A0A1B6E4W0   A0A1W4XIZ0   A0A1W4XUI3   A0A2P1JJ74   A0A323TN13   A0A0L8H1I1   A0A2P8Y7H6   A0A1S3J381   A0A3S1BHS4   A0A2P2I0B7   A0A1X7UQK7   H2ZCM4   A0A0P5W641   G3NKY4   A0A0P5Q4B3   V4AMB7   A0A0P4W3W2   A0A2D0PSZ9   A0A0P6IFG0   A0A1S3RX30   A0A1W2WBQ8   A0A3Q0JN07   A0A060XLD2   A0A2G8KQV6   G3NKW9   F6WBF5   A0A2D0PTW8   R7V2Y9   E9HNY5   K1QKM4   Q4T049   A7S4Q7   A0A385ZBK6   W7TK53   A0A3L7VVL8   A0A2R5GE83   A0A267E0P2   L8HKE1   A0A0P5HGF1   A0A267GIP4   A0A1I3NMJ5   A0A0C9RQC0   A0A3C1X2J0   A0A3L7UJA2   A0A3D3VYV7   D8T6N5   D8T6H4   A0A3L7N9T7   E4SGJ5   A0A0D6QWY3   A0A1Y1I2W2   A0A2K1KEJ1   A0A3B9D101   A0A1P8WEM4   A0A2E8FM44   A0A3R7Q3Y0   A0A352KY33   B9MPG8   A0A2U9AZT4   A0A3C1WG83   A0A2E7NK59   A9T7Y3   E4Q490   D9TIN9   A0A2P6TLE8   C3W9E8   A0A399ISP9   A0A2E7KCH8   A5ILR5   A0A3B8PKS3   A0A2R6DN25   Q8LFA4   A0A3M6TK47   A0A3B8LSF0   A0A0B5KKF0   B9K7G3   P45687   A0A1V4IEA1   E4QEE6   E4S4W9   G2PXL0   D2C8D9   A0A178PFM1   A0A101EPN0   G4FG56   Q9X1Z5   A0A329RCY7   A0A2H4G7K2   A0A2S2AYL7   A0A178UDJ9   Q9FKK7   A0A2E7RWH5  

PDB

1A0E     E-value=3.35997e-54,     Score=536

KEGG

101738927    K01805 xylose isomerase [EC:5.3.1.5] | (RefSeq) xylose isomerase-like

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00051    Fructose and mannose metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0009045   GO:0046872   GO:0042732   GO:0051539   GO:0016740   GO:0006400   GO:0005737   GO:0000287   GO:0016021   GO:0005975   GO:0042843   GO:0005783   GO:0005774   GO:0005773   GO:0005794   GO:0008152   GO:0016301   GO:0005179   GO:0005576   GO:0015074   GO:0015923   GO:0005634   GO:0006260  

Subcellular location

Cytoplasm  

Length:

462

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.12412

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00462

outside

1  -  462

 

 

Pi

242.522808

Theta

134.197512

Tajima's D

1.68769

CLR

0.348892

CSRT

0.827008649567522

Interpretation

Uncertain