Gene

KWMTBOMO06397  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011932

Annotation

PREDICTED:_uridine-cytidine_kinase-like_1_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr11(+):6342531-6357766      View in EpiBrowser

Full name

Uridine kinase      

Location in the cell

Cytoplasmic   Reliability : 1.409 Mitochondrial   Reliability : 1.702

CDS

ATGGCTGGGAAATTGAACAAATTCGAAACGCCCAGCTCTGCCAGCTCTGATAGCGACACTGAATTAGCGTTAGAGTTAAGCGAACAAGTATTCCTTGACGATGAAGACTACTCGAGCAGAGCTCCCGCCTCGCCCACAACTGTACCGAACGTGCGACCATACAGACCTCCGTCCACCGGATCGAATATACTGAAGTCTCCGCGAGCGAGGCGCGTCCGCACAACGTCAATGTCACAGTCAAACAAACGCACAGCGGCCGAGAGCATTCTTCATGCTGACAAAAGGACTATATACACCGCCGGCAGACCCCCCTGGTACAACTGTACAGGGGGGCAGGAGGTGGAACCCTTTCTTATAGGTATATGCGGCGCGAGTGCGTCCGGCAAGACGACAGTGGCTGCCAAAATCATAGAATCTCTCAACATACCCTGGGTCACTATCGTCAGCATGGATTCATTTTACAAAGTACTTAACGAGAAACAGCACCACCTGGCGGCCCTCAACGAATATAACTTCGACCACCCTGACGCCTTCGACATGGAGTTGCTGGTTAGCGTGCTGCAGCGGCTTCGCGAGGGAAAGAAAGTGGAAGTTCCGATATACAACTACGTCACGCACGCGAGGGAGAATAGAACTAAAACAATGTACGGCGCGAACGTGATAATATTTGAAGGCATTCTGGCCTTCTACAACGCGGAGGTGCTGAAGCTTCTGGACATGAAGGTGTTCGTGGACACGGACGCCGACATACGGCTCGCCAGGAGACTGCGCAGGGACATCGTGCAGCGCGGGCGCGAGCTGGAGGGCGTGCTGAAGCAGTACATGACGTACGTGAAGCCCGCCTACCAGAACTACATCGCGCCGTGCATGGCGCACGCCGACATCATCGTGCCGCGCGGCGGGGAGAACAAGGTCGCCATCCACCTCATCGTGCAGCACGTGCACAAGCAGCTGCAGCTGCGCGGGTTCAAGGTGCGCGAGAAGCTGGCGGTGGCGCACGTGGGCCAGCCCGTGCCCGACTCGCTCTACGTGCTCGAGAACACGCCGCAGGTGCAGGGGCTCCACACGTTCATACGCAACAAGGACACGCCGCGGGACGAGTTCATATTCTACTCTAAGCGCCTGATGCGCCTCGTCATAGAGTTCGCGCTGTCGCTGCAGCCCTACGCGCCGCGCACCGTGGACACGCCGCAGGGGATCGCCTACCACGGTCGGAAGTGCGAGGTGGAGAAGATATGTGGCGTGTCCATCCTGCGCGCCGGTGAGACCATGGAGCAGGCCGTGTGCGACGTGTGCAAGGACATCCGCATCGGGAAGATACTCATCCAGACCAACCAGCTCACGGACGAGCCCGAGCTCTACTACCTGCGGCTGCCCAAGGACATCAAGGACTACCGCGTGATCCTGATGGACGCGACGGTGGCGACGGGCGCGGCCGCCATCATGGCCATCCGCGTGCTGCTGGACCACGACGTGCCGGAGCACTGCATCAGCCTCGTGTCGCTGCTCATGGCGGACGCGGGCGCGCACTCCATCGCCTACGCCTTCCCGCAGGTAAAGATCGTAACGTCGGCCCTGGATCCCGAGATCAACGAGAAGTTCTACGTGCTGCCCGGGATAGGCAACTTCGGCGACCGGTATTTCGGCACCGAGCCCGCCGACGACGAGTGA

Protein

MAGKLNKFETPSSASSDSDTELALELSEQVFLDDEDYSSRAPASPTTVPNVRPYRPPSTGSNILKSPRARRVRTTSMSQSNKRTAAESILHADKRTIYTAGRPPWYNCTGGQEVEPFLIGICGASASGKTTVAAKIIESLNIPWVTIVSMDSFYKVLNEKQHHLAALNEYNFDHPDAFDMELLVSVLQRLREGKKVEVPIYNYVTHARENRTKTMYGANVIIFEGILAFYNAEVLKLLDMKVFVDTDADIRLARRLRRDIVQRGRELEGVLKQYMTYVKPAYQNYIAPCMAHADIIVPRGGENKVAIHLIVQHVHKQLQLRGFKVREKLAVAHVGQPVPDSLYVLENTPQVQGLHTFIRNKDTPRDEFIFYSKRLMRLVIEFALSLQPYAPRTVDTPQGIAYHGRKCEVEKICGVSILRAGETMEQAVCDVCKDIRIGKILIQTNQLTDEPELYYLRLPKDIKDYRVILMDATVATGAAAIMAIRVLLDHDVPEHCISLVSLLMADAGAHSIAYAFPQVKIVTSALDPEINEKFYVLPGIGNFGDRYFGTEPADDE

Catalytic Activity

ATP + cytidine = ADP + CMP + H(+)
ATP + uridine = ADP + H(+) + UMP

Similarity

Belongs to the uridine kinase family.

Feature

chain  Uridine kinase

Uniprot

A0A2A4JHW5   A0A3S2LIH0   A0A2A4JIQ3   A0A212FDW7   A0A2Z5UIM3   A0A194PWM0   + More
A0A2W1BYF4   H9JQX6   A0A2J7PJS0   A0A0C9QP02   A0A026WLZ0   E9I9V6   A0A195CJP8   E2AT07   A0A195E5M2   F4W458   A0A195B479   A0A158NF19   A0A151X266   A0A195ETA6   A0A067R085   A0A232F2R1   A0A0L7LBM3   A0A0M9A684   D6W6C4   A0A2J7PJS1   U5ESP1   E2B6P7   A0A1B6DMB5   A0A154PCA0   A0A1B6E793   A0A0K8TSP4   A0A2S2RAF4   B0X066   A0A1S4FST9   A0A1B6HKH6   A0A0A9YDW2   A0A2H8TJC6   Q16QI9   A0A023EUT9   A0A023F5K1   A0A069DVN4   A0A2S2P4P2   X1X1Y2   A0A310SUW7   A0A0P4VUD7   A0A224XMR6   A0A1B6L5I5   W8BGJ9   A0A1Q3FDI4   A0A1Y1L7I3   A0A034W8B3   A0A1L8DJ67   A0A034W9U3   W8C3B7   A0A034W4M1   W8BTX0   W8CA20   A0A1W4XJC2   B3MG64   B4MQJ0   A0A1B6EV68   A0A0P8XP30   A0A182QYB9   K7J2T4   A0A1W4XUD2   A0A087ZVQ9   A0A1W4VDA9   A0A084WJI7   A0A1W4VBZ4   A0A1W4V040   B4LPX0   B4KR00   A0A182RKV3   A0A3B0JH38   B4J917   A0A182P8R9   A0A182IQC1   A0A182XEW0   Q5TSQ7   A0A182HNY5   A0A182NQ55   A0A182YC46   B3NNS0   A0A0L7QSW4   A0A182K8H8   A0A0Q5VXT3   A0A182WK29   B4P807   B5E031   B4GAQ5   Q8MQK4   A0A0R1DT41   A0A2M4BJI2   A0A0R3NLZ1   A0A0R3NSZ0   A1ZAS3   A0A2M4AFR4   A0A2M3Z7Y4   A0A182FCY4  

EC Number

2.7.1.48

Pubmed

22118469    26354079    28756777    19121390    24508170    30249741    + More
21282665    20798317    21719571    21347285    24845553    28648823    26227816    18362917    19820115    26369729    25401762    26823975    17510324    24945155    26483478    25474469    26334808    27129103    24495485    28004739    25348373    17994087    20075255    24438588    12364791    14747013    17210077    25244985    18057021    17550304    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356   

EMBL

NWSH01001334    PCG71647.1    RSAL01000104    RVE47368.1    PCG71646.1    AGBW02008998    + More
OWR51898.1    AP017476    BBB06712.1    KQ459590    KPI97154.1    KZ149897    PZC78685.1    BABH01028575    NEVH01024946    PNF16587.1    GBYB01005279    JAG75046.1    KK107153    QOIP01000012    EZA56983.1    RLU15811.1    GL761846    EFZ22673.1    KQ977642    KYN00955.1    GL442439    EFN63442.1    KQ979609    KYN20149.1    GL887491    EGI71054.1    KQ976625    KYM79014.1    ADTU01001499    KQ982585    KYQ54284.1    KQ981979    KYN31485.1    KK852833    KDR15301.1    NNAY01001153    OXU24975.1    JTDY01001892    KOB72616.1    KQ435727    KOX78077.1    KQ971319    EFA11381.2    PNF16586.1    GANO01003152    JAB56719.1    GL446000    EFN88631.1    GEDC01010442    JAS26856.1    KQ434870    KZC09526.1    GEDC01003574    JAS33724.1    GDAI01000638    JAI16965.1    GGMS01017447    MBY86650.1    DS232229    EDS37941.1    GECU01032523    JAS75183.1    GBHO01014311    GBHO01014309    GBRD01008538    GBRD01008537    GDHC01009665    JAG29293.1    JAG29295.1    JAG57283.1    JAQ08964.1    GFXV01002411    MBW14216.1    CH477747    EAT36651.1    JXUM01074255    JXUM01074256    GAPW01000857    KQ562819    JAC12741.1    KXJ75061.1    GBBI01002272    JAC16440.1    GBGD01001033    JAC87856.1    GGMR01011820    MBY24439.1    ABLF02031447    ABLF02031448    KQ760208    OAD61380.1    GDKW01000949    JAI55646.1    GFTR01007137    JAW09289.1    GEBQ01020998    JAT18979.1    GAMC01006155    JAC00401.1    GFDL01009432    JAV25613.1    GEZM01066410    GEZM01066409    JAV67905.1    GAKP01008405    GAKP01008403    JAC50547.1    GFDF01007576    JAV06508.1    GAKP01008404    GAKP01008402    JAC50548.1    GAMC01006154    GAMC01006150    JAC00402.1    GAKP01008401    JAC50551.1    GAMC01006152    JAC00404.1    GAMC01006151    JAC00405.1    CH902619    EDV36759.1    CH963849    EDW74379.1    GECZ01027999    JAS41770.1    KPU76399.1    AXCN02001020    ATLV01024035    KE525348    KFB50381.1    CH940648    EDW61310.2    CH933808    EDW10356.2    OUUW01000001    SPP74690.1    CH916367    EDW01366.1    AAAB01008900    EAL40491.3    APCN01002812    CH954179    EDV55627.1    KQ414755    KOC61743.1    KQS62350.1    CM000158    EDW92162.1    CM000071    EDY68915.1    CH479181    EDW32007.1    AE013599    AY129436    AAF57871.3    AAM76178.1    KRK00348.1    GGFJ01003807    MBW52948.1    KRT01874.1    KRT01875.1    BT125900    AAF57873.2    ADV19041.1    GGFK01006303    MBW39624.1    GGFM01003849    MBW24600.1   

Proteomes

UP000218220    UP000283053    UP000007151    UP000053268    UP000005204    UP000235965    + More
UP000053097    UP000279307    UP000078542    UP000000311    UP000078492    UP000007755    UP000078540    UP000005205    UP000075809    UP000078541    UP000027135    UP000215335    UP000037510    UP000053105    UP000007266    UP000008237    UP000076502    UP000002320    UP000008820    UP000069940    UP000249989    UP000007819    UP000192223    UP000007801    UP000007798    UP000075886    UP000002358    UP000005203    UP000192221    UP000030765    UP000008792    UP000009192    UP000075900    UP000268350    UP000001070    UP000075885    UP000075880    UP000076407    UP000007062    UP000075840    UP000075884    UP000076408    UP000008711    UP000053825    UP000075881    UP000075920    UP000002282    UP000001819    UP000008744    UP000000803    UP000069272   

PRIDE

H9JQX6    Q8MQK4    A1ZAS3   

Pfam

PF00485   PRK

Interpro

IPR029933   UCKL1        + More
IPR006083   PRK/URK       
IPR000764   Uridine_kinase-like       
IPR027417   P-loop_NTPase       
IPR029057   PRTase-like       
IPR000836   PRibTrfase_dom       

SUPFAM

SSF52540   SSF52540        + More
SSF53271   SSF53271       

CDD

cd02023  UMPK
cd06223  PRTases_typeI

ProteinModelPortal

A0A2A4JHW5   A0A3S2LIH0   A0A2A4JIQ3   A0A212FDW7   A0A2Z5UIM3   A0A194PWM0   + More
A0A2W1BYF4   H9JQX6   A0A2J7PJS0   A0A0C9QP02   A0A026WLZ0   E9I9V6   A0A195CJP8   E2AT07   A0A195E5M2   F4W458   A0A195B479   A0A158NF19   A0A151X266   A0A195ETA6   A0A067R085   A0A232F2R1   A0A0L7LBM3   A0A0M9A684   D6W6C4   A0A2J7PJS1   U5ESP1   E2B6P7   A0A1B6DMB5   A0A154PCA0   A0A1B6E793   A0A0K8TSP4   A0A2S2RAF4   B0X066   A0A1S4FST9   A0A1B6HKH6   A0A0A9YDW2   A0A2H8TJC6   Q16QI9   A0A023EUT9   A0A023F5K1   A0A069DVN4   A0A2S2P4P2   X1X1Y2   A0A310SUW7   A0A0P4VUD7   A0A224XMR6   A0A1B6L5I5   W8BGJ9   A0A1Q3FDI4   A0A1Y1L7I3   A0A034W8B3   A0A1L8DJ67   A0A034W9U3   W8C3B7   A0A034W4M1   W8BTX0   W8CA20   A0A1W4XJC2   B3MG64   B4MQJ0   A0A1B6EV68   A0A0P8XP30   A0A182QYB9   K7J2T4   A0A1W4XUD2   A0A087ZVQ9   A0A1W4VDA9   A0A084WJI7   A0A1W4VBZ4   A0A1W4V040   B4LPX0   B4KR00   A0A182RKV3   A0A3B0JH38   B4J917   A0A182P8R9   A0A182IQC1   A0A182XEW0   Q5TSQ7   A0A182HNY5   A0A182NQ55   A0A182YC46   B3NNS0   A0A0L7QSW4   A0A182K8H8   A0A0Q5VXT3   A0A182WK29   B4P807   B5E031   B4GAQ5   Q8MQK4   A0A0R1DT41   A0A2M4BJI2   A0A0R3NLZ1   A0A0R3NSZ0   A1ZAS3   A0A2M4AFR4   A0A2M3Z7Y4   A0A182FCY4  

PDB

1UJ2     E-value=2.85334e-53,     Score=529

KEGG

101744022    K00876 uridine kinase [EC:2.7.1.48] | (RefSeq) uridine-cytidine kinase-like 1

PATHWAY

00240    Pyrimidine metabolism - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0004849   GO:0009116   GO:0044211   GO:0044206   GO:0016301   GO:0016021   GO:0008655   GO:0005737   GO:0005634   GO:0008152   GO:0005179   GO:0005576   GO:0015074   GO:0015923   GO:0006260  

PANTHER

PTHR10285:SF68  

Length:

556

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

5.03063

Exp number, first 60 AAs:

0

Total prob of N-in:

0.15054

outside

1  -  556

 

 

Pi

225.027914

Theta

184.778607

Tajima's D

1.048363

CLR

0.488905

CSRT

0.672016399180041

Interpretation

Uncertain