Gene

KWMTBOMO06361

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr11(+):5708008-5711506      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.526 Nuclear   Reliability : 2.204

CDS

ATGGCGCAAAACGCTAGAGAGAAACCATATTCCCTTACGTTAGCATTCTACAATGCTAACGGACTCGCGCGACAACGCGATCAAATTTACGAATTCCTCCGCGACAATCTTGTAGATATTCTGCTAGTGCAGGAGACCTGCCTGAAGCCCTCGCGTCGTGACCCGAAAGTCGCGAATTACGTCATGGTTAGGAATGACAGACTCACCGCCTCCAAAGGCGGGACTGCCATTTACTATAGGCGGGCCCTGCACGTTGTCCCTCTCGATACCCCCTCGCTCTCACATATCGAGGCGTCAGTGTGCCGTATCTCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTTCTGAGCAGTGACATCGAGTCACTGTTCGGCATGGGAGACTCCGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCACAGTTCAAACATAAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTTACCTTTGAAGTAGTCGGTCCCCCAACTCCAACATTCACAGCTACGAGGACCATGGTGGACTGGAAGAAGCTGGGCAAATGCTTAGCCGATGCCGCTCCACCAATCCTCCCCTGCGGCCCGGATTCAACTCCATCCCCCGAGGACACAGTCGAATCCATAAACATCATCACGGATCACATCTCTTCCGCGATCATAAGATCCTCAAAAGAAGTCGATGTGGAGGATAGCTTCCACCGCATCAGACTGTCCCCCGAACTTAGGAACCTCCTAAGAGTTAGAAACGCGGCAATCCTGGCCTACGATCAACTTCCCACGCACTCAAACCGGATTCGGATGCGTCGTCTACAGCGGGATGTAAAATCTCGCCTAAGCGACGCCCGAAATGAGAATTGGGATAGTTACTTAGAAGGACTCGCGCCCTCTCATCAAGCATACTGGCGACTAGCAAGGACTCTCAAGTCCGAAACTACCGCTACTATGCCTCCTCTCGTACGCCCTTCAGGCCAACCACCGGCTTTCGATGACGATGACAAGGCAGAGTTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAATACGCGGACCCCGAACACACCGAGGCAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCACCCTCGGACGCGTTACCCCCCATTACCTCTGACGAAGTTAGAGAAGTAATAGACAACCTTCAACCTAAGAAGGCACCCGGCTCCGACGGCATCCGCAACCGCGCGTTAAAACTCTTACCAGTCCAACTGATAACAATGTTGGCTACCATCTTAAATGCCGCTATGACGCACTGCATCTTTCCGGCGGTATGGAAAGAAGCAGACGTTATCGGTATACACAAGCCGGGCAAACCGAATAATGAAACCGCTAGTTACCGACCGATTAGTCTCCTCCCAGCGATAGGCAAAATTTACGAACGGCTCCTTCGGAAACGCCTCTGGGACTTCGTTACCGCGAATAAAATTCTAATAGACGAGCAGTTTGGATTCCGCGCCAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATCTTAATAGGGCTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGATGTAGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTGATCTACAAACTGTACAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTTCTTGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCATCTGACTGCCGGAGTCCCGCAAGGCTCCGCACTCTCCCCGTTACTATTTAGTTTGTATATTAACGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGTTGCTTCATCGGCGACTCCAGACCGCAGTAACCACCATGGGACAGTGGTTCCGGAAGTGGCGAATAGACATTAACCCCACGAAAAGCACAGCGGTGCTATTCAAAAGGGGTCGCCCTCCGAATACCACTTCGAGCACCCCACTCCCCAATAGGCGCGTAAACACCTCCGCCGTTAGCCCCATCACTCTCTTTGACCAGCCCATACCGTGGGCCCCGAAGGTCAAATACCTAGGCGTCACCCTCGACAGAGGGATGACATTCCGTCCCCACGTAAAAACGGTACGCGATCGCGCCGCGTTTATACTAGGACGACTCTACCCAATGCTTTGTAGACGAAGCAAACTGTCCCTCCGTAATAAGGTAACCCTCTACAAAACTTGCATACGCCCCGTCATGACGTATGCAAGCGTAGTGTTCGCTCACGCGGCCCGCACCAACTTGAAACCCCTTCAGGTTATACAATCCCGATTCTGCAGGATAGCCGTCGGAGCACCATGGTTCCAGAGGAACGTGGACCTCCACGATGACCTGGAGCTCGACCCCGTCAGTAAGTATCTACAGTCGGCATCGCTGCGCCACTTTGAGAAGGCGGCACGACATGAGAACCCTCTTGTCGTGGCCGCCGGAAACTACATACCCGATCCTGTAGACCGTTTGGTAAAGATCAGGATATTAAAGCTTGTAAGAGTAAGTCAAAGTATTCTTCTCTAG

Protein

MAQNAREKPYSLTLAFYNANGLARQRDQIYEFLRDNLVDILLVQETCLKPSRRDPKVANYVMVRNDRLTASKGGTAIYYRRALHVVPLDTPSLSHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVILAGDLNCHHTRWNCHSSNINGRRLDAFIDDLTFEVVGPPTPTFTATRTMVDWKKLGKCLADAAPPILPCGPDSTPSPEDTVESINIITDHISSAIIRSSKEVDVEDSFHRIRLSPELRNLLRVRNAAILAYDQLPTHSNRIRMRRLQRDVKSRLSDARNENWDSYLEGLAPSHQAYWRLARTLKSETTATMPPLVRPSGQPPAFDDDDKAELLADALQEQCTTSTQYADPEHTEAVDREVERRASLPPSDALPPITSDEVREVIDNLQPKKAPGSDGIRNRALKLLPVQLITMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPNNETASYRPISLLPAIGKIYERLLRKRLWDFVTANKILIDEQFGFRAKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDVAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDFLSNRSFRYRVEGTRSRPRHLTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKMSLLHRRLQTAVTTMGQWFRKWRIDINPTKSTAVLFKRGRPPNTTSSTPLPNRRVNTSAVSPITLFDQPIPWAPKVKYLGVTLDRGMTFRPHVKTVRDRAAFILGRLYPMLCRRSKLSLRNKVTLYKTCIRPVMTYASVVFAHAARTNLKPLQVIQSRFCRIAVGAPWFQRNVDLHDDLELDPVSKYLQSASLRHFEKAARHENPLVVAAGNYIPDPVDRLVKIRILKLVRVSQSILL

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNF3   V5GNJ2   A0A023EYS8   D7EM17   A0A023EZE6   X1WLB2   A0A2S2Q383   A0A3N5Z7I3   Q07995   A0A2M4BD67   A0A2M4BDV6   A0A2S2QEE0   A0A224XF24   A0A087UGF5   A0A2J7R7D0   A0A224X6S1   A0A2S2N814   A0A2S2NGV8   A0A224X6T4   X1WNI2   A0A224XI99   A0A2S2P698   A0A224X6U5   A0A2J7QR37   A0A2H8TF37   A0A2J7PU96   A0A2S2R9D4   X1WQI9   A0A2J7PBY3   A0A2J7QB68   A0A2J7QY69   A0A224X6R6   A0A2J7PVX3   A0A069DZL8   J9LFC9   A0A2M4BD66   A0A2M4BDA5   J9LC21   A0A2M4BD62   X1WZH0   A0A2H8TKI9   A0A2S2PHL7   A0A069DX78   A0A224X746   A0A224X6W2   A0A2S2NPG3   A0A2S2PJG2   A0A2M4BD83   A0A224XHW8   P21328   A0A2M4CVF1   A0A2J7PDM0   A0A2S2PA10   A0A2S2NH02   A0A2M4CVK2   K7IN67   A0A1Y1KFR3   A0A224XJI0   A0A1Y1LKN6   A0A2H8U0H5   A0A2S2P6S3   A0A2J7RD70   V9GZF1   A0A2S2P3X8   Q95SX7   A0A2J7PQB5   J9KLB1   Q8I7P8   A0A0V0G5B6   A0A2M4BEF4   A0A2S2P6C4   A0A0A9YJ00   A0A0A9YU04   Q04135   A0A023F0I3   A0A2S2N6Q7   A0A2M4BEZ9   P21329   X1WUG2  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    30086797    8387152    26334808    2463954    3040362    1714378    20075255    1327974    7753626    12537569    25401762    1705654    1701254   

EMBL

U07847    AAA17752.1    AB055391    BAB21761.1    AB018558    BAA76304.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    GALX01005299    JAB63167.1    GBBI01004395    JAC14317.1    KQ973412    EFA12510.2    GBBI01004571    JAC14141.1    ABLF02042518    ABLF02057746    GGMS01002992    MBY72195.1    RPOV01000134    RPJ78669.1    S59870    AAB26437.2    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    GGMS01006359    MBY75562.1    GFTR01008038    JAW08388.1    KK119692    KFM76444.1    NEVH01006736    PNF36716.1    GFTR01008271    JAW08155.1    GGMR01000676    MBY13295.1    GGMR01003407    MBY16026.1    GFTR01008261    JAW08165.1    ABLF02008153    ABLF02008462    ABLF02008464    GFTR01008256    JAW08170.1    GGMR01012305    MBY24924.1    GFTR01008251    JAW08175.1    NEVH01011985    PNF31054.1    GFXV01000908    MBW12713.1    NEVH01021205    PNF19912.1    GGMS01017365    MBY86568.1    ABLF02022418    NEVH01027074    PNF13841.1    NEVH01016302    PNF25823.1    NEVH01009134    PNF33528.1    GFTR01008269    JAW08157.1    NEVH01020940    PNF20481.1    GBGD01000415    JAC88474.1    ABLF02023911    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GGFJ01001843    MBW50984.1    ABLF02034467    GFXV01002840    MBW14645.1    GGMR01016296    MBY28915.1    GBGD01000389    JAC88500.1    GFTR01008151    JAW08275.1    GFTR01008260    JAW08166.1    GGMR01006408    MBY19027.1    GGMR01016905    MBY29524.1    GGFJ01001822    MBW50963.1    GFTR01008254    JAW08172.1    M22874    M38643    GGFL01005122    MBW69300.1    NEVH01026386    PNF14434.1    GGMR01013409    MBY26028.1    GGMR01003864    MBY16483.1    GGFL01005121    MBW69299.1    GEZM01084969    JAV60363.1    GFTR01008257    JAW08169.1    GEZM01053022    JAV74219.1    GFXV01007093    MBW18898.1    GGMR01012443    MBY25062.1    NEVH01005295    PNF38784.1    M95171    AAA29354.1    GGMR01011511    MBY24130.1    AY060438    AAL25477.1    NEVH01022639    PNF18527.1    ABLF02040174    ABLF02040183    ABLF02055266    AY180919    AAN87272.1    GECL01003538    JAP02586.1    GGFJ01002256    MBW51397.1    GGMR01012283    MBY24902.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    X17551    CAA35587.1    GBBI01003747    JAC14965.1    GGMR01000226    MBY12845.1    GGFJ01002257    MBW51398.1    M38437    ABLF02016613   

Proteomes

UP000053268    UP000007266    UP000007819    UP000054359    UP000235965    UP000002358    + More

PRIDE

Q93137    Q9BPQ0    Q9XXW0    P21328    Q95SX7    Q8I7P8    + More
Q04135    P21329   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNF3   V5GNJ2   A0A023EYS8   D7EM17   A0A023EZE6   X1WLB2   A0A2S2Q383   A0A3N5Z7I3   Q07995   A0A2M4BD67   A0A2M4BDV6   A0A2S2QEE0   A0A224XF24   A0A087UGF5   A0A2J7R7D0   A0A224X6S1   A0A2S2N814   A0A2S2NGV8   A0A224X6T4   X1WNI2   A0A224XI99   A0A2S2P698   A0A224X6U5   A0A2J7QR37   A0A2H8TF37   A0A2J7PU96   A0A2S2R9D4   X1WQI9   A0A2J7PBY3   A0A2J7QB68   A0A2J7QY69   A0A224X6R6   A0A2J7PVX3   A0A069DZL8   J9LFC9   A0A2M4BD66   A0A2M4BDA5   J9LC21   A0A2M4BD62   X1WZH0   A0A2H8TKI9   A0A2S2PHL7   A0A069DX78   A0A224X746   A0A224X6W2   A0A2S2NPG3   A0A2S2PJG2   A0A2M4BD83   A0A224XHW8   P21328   A0A2M4CVF1   A0A2J7PDM0   A0A2S2PA10   A0A2S2NH02   A0A2M4CVK2   K7IN67   A0A1Y1KFR3   A0A224XJI0   A0A1Y1LKN6   A0A2H8U0H5   A0A2S2P6S3   A0A2J7RD70   V9GZF1   A0A2S2P3X8   Q95SX7   A0A2J7PQB5   J9KLB1   Q8I7P8   A0A0V0G5B6   A0A2M4BEF4   A0A2S2P6C4   A0A0A9YJ00   A0A0A9YU04   Q04135   A0A023F0I3   A0A2S2N6Q7   A0A2M4BEZ9   P21329   X1WUG2  

PDB

6AR3     E-value=0.016256,     Score=93

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

881

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.404130000000001

Exp number, first 60 AAs:

0.00127

Total prob of N-in:

0.01063

outside

1  -  881

 

 

Pi

13.78297

Theta

3.414605

Tajima's D

0.79752

CLR

257.778612

CSRT

0.635368231588421

Interpretation

Uncertain