Gene

KWMTBOMO06332  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011992

Annotation

PREDICTED:_protein-lysine_N-methyltransferase_mettl10_[Papilio_polytes]

Location

Bomo_Chr11(-):4881756-4890072      View in EpiBrowser

Full name

Protein-lysine N-methyltransferase 101736309       + More
Protein-lysine N-methyltransferase B5X24_HaOG208517      
Protein-lysine N-methyltransferase SFRICE_013511      
Protein-lysine N-methyltransferase evm_008133      
Protein-lysine N-methyltransferase RR48_01791      
Protein-lysine N-methyltransferase RR46_02523      
Protein-lysine N-methyltransferase KGM_206213      
Protein-lysine N-methyltransferase      
Protein-lysine N-methyltransferase AAEL000284      
Protein-lysine N-methyltransferase CpipJ_CPIJ006933      
Protein-lysine N-methyltransferase ZHAS_00012982      
Protein-lysine N-methyltransferase AND_003655      
Protein-lysine N-methyltransferase AgaP_AGAP005673      
Protein-lysine N-methyltransferase L798_03561      
Protein-lysine N-methyltransferase LOC552181      
Protein-lysine N-methyltransferase 106081964      
Protein-lysine N-methyltransferase CM83_54793      
Protein-lysine N-methyltransferase 101892790      
Protein-lysine N-methyltransferase APICC_02220      
Protein-lysine N-methyltransferase Dmoj_GI18358      
Protein-lysine N-methyltransferase CAPTEDRAFT_181492      
Protein-lysine N-methyltransferase g.4659      
Protein-lysine N-methyltransferase FF38_04263      
Protein-lysine N-methyltransferase MET10      
Protein-lysine N-methyltransferase g.57116      
Protein-lysine N-methyltransferase LOC108092460      
Protein-lysine N-methyltransferase Dana_GF14906      
Protein-lysine N-methyltransferase g.24745      
Protein-lysine N-methyltransferase c0_g1_i1      
Protein-lysine N-methyltransferase C7M84_001690      
Protein-lysine N-methyltransferase g.24743      
Protein-lysine N-methyltransferase ALC56_05962      
Protein-lysine N-methyltransferase WN51_00858      
Protein-lysine N-methyltransferase 105625771      
Protein-lysine N-methyltransferase ALC53_02637      
Protein-lysine N-methyltransferase Dgri_GH20919      
Protein-lysine N-methyltransferase ALC57_18058      
Protein-lysine N-methyltransferase CSON008894      
Protein-lysine N-methyltransferase TSAR_003890      
Protein-lysine N-methyltransferase Dwil_GK15575      
Protein-lysine N-methyltransferase LOC106152745      
Protein-lysine N-methyltransferase WN48_00932      
Protein-lysine N-methyltransferase Dvir_GJ21427      
Protein-lysine N-methyltransferase 100119460      
Protein-lysine N-methyltransferase ALC60_12581      
Protein-lysine N-methyltransferase Dbus_chr2Rg1434      
Protein-lysine N-methyltransferase C0J52_19863      
Protein-lysine N-methyltransferase DMN91_001615      
Protein-lysine N-methyltransferase g.24742      
Protein-lysine N-methyltransferase AWC38_SpisGene16704      
Protein-lysine N-methyltransferase pdam_00004949      
Protein-lysine N-methyltransferase TrispH2_004911      
Protein-lysine N-methyltransferase TRIADDRAFT_23674      
Protein-lysine N-methyltransferase DGUA_6G014227      
EEF1A lysine methyltransferase 2      
Protein-lysine N-methyltransferase WN55_04819      
Protein-lysine N-methyltransferase LOC106154172      
Protein-lysine N-methyltransferase TcasGA2_TC003501      

Alternative Name

Methyltransferase-like protein 10
Protein-lysine N-methyltransferase METTL10

Location in the cell

Cytoplasmic   Reliability : 3.876

CDS

ATGGATGAAACGGAATTAGACCCGTCCGTATTAGGAACTCGTGAGTACTGGAAAGAGGCTTACGCTAAAGAAATTCGGAATTTCGATGAGTTTGGTGATACCGGAGACGTTTGGTTCGGTGAAGACAGTGCCCTCCGAGTAATAAGGTGGATCTGCGACTGCGGGGTGGACAGAAACAGTCCCATCATCGACTTAGGCTGTGGAAACGGTTACACACTATCTGAATTAGCAAAAGAAGGATTCACAAATCTACTCGGAGTGGATTACTGCGAGGCTGCCATTACTTTAGCCCGAAAAGTTGCCAAGCAGAATTATCCCTTCATCAACTATAAGTTATTCGACATAACAACGGACGATGTAATAGCGTTGGGCCAATATGCCATAGTTCATGACAAGGGCACATACGATGCTATAGGCCTGAATCCCATAGACCCTAAAGCCTGCCGAGAGAAATACATCGAACAAATTCATAGACTGCTCCTCGATGAGGGTATTTTCATAATAACATCATGCAATTGGACCGAAGAGGAATTAGTTAAACATTTTTCCGAGAAAATGAAATTGAAATGCGTACTACCGACTCCGCAGTTCCGTTTTGGCGGGAAAGTCGGAAGCGTTGTGTCGTCTGTGGTGTTTTGTAAAAAATAA

Protein

MDETELDPSVLGTREYWKEAYAKEIRNFDEFGDTGDVWFGEDSALRVIRWICDCGVDRNSPIIDLGCGNGYTLSELAKEGFTNLLGVDYCEAAITLARKVAKQNYPFINYKLFDITTDDVIALGQYAIVHDKGTYDAIGLNPIDPKACREKYIEQIHRLLLDEGIFIITSCNWTEEELVKHFSEKMKLKCVLPTPQFRFGGKVGSVVSSVVFCKK

Description

S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.
Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.

Uniprot

H9JR32   A0A2W1BJR8   A0A2H1W911   A0A3S2LYV6   A0A0N1IH50   A0A194Q3M5   + More
A0A212FHA5   S4PWS0   Q17PM4   A0A023ELE3   A0A1Q3FA79   A0A182M0T4   A0A2M4BZ46   A0A2M4BZ68   A0A2M4BYY1   A0A2M4BZ00   B0WIK4   A0A084W496   A0A2M4AX98   A0A182PHP5   A0A182FPB3   W5JKD9   A0A182WIG3   A0A182TYF4   A0A182XMU9   Q7Q6T8   A0A182HWQ6   A0A182RIG9   A0A182LJ17   A0A182QDJ8   A0A182K278   A0A182Y1B9   A0A182VC46   A0A0L7L229   A0A1B0CZP0   A0A067QSZ5   A0A182NGY3   A0A087ZU12   A0A1I8PET5   A0A0A9WG81   A0A1I8MQF2   A0A2A3EJ95   T1GUJ9   B4KM11   R7V743   A0A1B6KAE0   A0A0L0BWP3   A0A1B0FKT4   A0A1J1HI76   A0A1A9Z697   A0A1A9VU02   A0A034WN47   A0A0A1XEG3   A0A1W4UUA0   A0A1B0AUB6   B3MLC2   A0A1B6E826   A0A1A9XD40   A0A0K8UVN7   A0A1B0CSL2   A0A3R7QI16   A0A1B6BZS1   E9IFZ1   W8BQ09   A0A195FHI7   A0A0M9AB85   A0A158NY75   A0A195BQM3   A0A1L8DBP8   B4J4Q6   A0A1L8DCH0   A0A151ISE3   A0A336LGD4   A0A232EQ97   B4MX24   A0A1S3H7F8   A0A310SLJ6   B4LQ29   K7J6F5   A0A151WK47   A0A0M4EKE7   A0A023F7J2   A0A2P8XPT3   A0A3L8DZV5   A0A1B6D9L9   A0A023GGG7   A0A2B4RQ29   A0A131Y7Z4   A0A3M6UVS4   A0A369S7W7   B3RUN0   A0A0K8R7P6   A0A1Y1MYF7   A0A3B0K9Q2   H3B1B8   A0A154NZ95   A0A1U7S5N0   A0A1S3HCX4   A0A224Z2R2   D6WH31  

EC Number

2.1.1.-

Pubmed

19121390    28756777    26354079    22118469    23622113    17510324    + More
24945155    24438588    20920257    23761445    12364791    14747013    17210077    20966253    25244985    26227816    24845553    25401762    26823975    25315136    17994087    23254933    26108605    25348373    25830018    21282665    24495485    21347285    28648823    20075255    25474469    29403074    30249741    30382153    30042472    18719581    28004739    9215903    28797301    18362917    19820115   

EMBL

BABH01028704    BABH01028705    KZ150077    PZC73945.1    ODYU01006795    SOQ48974.1    + More
RSAL01000109    RVE47165.1    KQ459736    KPJ20223.1    KQ459564    KPI99609.1    AGBW02008515    OWR53121.1    GAIX01006303    JAA86257.1    CH477190    EAT48728.1    GAPW01004524    JAC09074.1    GFDL01010642    JAV24403.1    AXCM01010306    GGFJ01009162    MBW58303.1    GGFJ01009161    MBW58302.1    GGFJ01009156    MBW58297.1    GGFJ01009155    MBW58296.1    DS231949    EDS28527.1    ATLV01020296    KE525297    KFB45040.1    GGFK01012105    MBW45426.1    ADMH02000945    ETN64596.1    AAAB01008960    EAA11809.3    APCN01001524    AXCN02000353    JTDY01003483    KOB69485.1    AJVK01009648    KK853575    KDR06587.1    GBHO01040411    GBHO01039738    GBHO01039737    GBHO01039734    GBHO01039733    GBRD01002944    GDHC01015918    GDHC01014657    GDHC01012139    JAG03193.1    JAG03866.1    JAG03867.1    JAG03870.1    JAG03871.1    JAG62877.1    JAQ02711.1    JAQ03972.1    JAQ06490.1    KZ288227    PBC31855.1    CAQQ02005771    CH933808    EDW10800.1    AMQN01005688    KB296584    ELU11590.1    GEBQ01031568    JAT08409.1    JRES01001236    KNC24431.1    CCAG010000747    CVRI01000004    CRK87717.1    GAKP01001946    JAC57006.1    GBXI01004957    JAD09335.1    JXJN01003604    CH902620    EDV30711.1    GEDC01003232    JAS34066.1    GDHF01021597    JAI30717.1    AJWK01026191    AJWK01026192    AJWK01026193    QCYY01001223    ROT79579.1    GEDC01030684    GEDC01018130    JAS06614.1    JAS19168.1    GL762905    EFZ20512.1    GAMC01003225    JAC03331.1    KQ981606    KYN39469.1    KQ435694    KOX80940.1    ADTU01000590    KQ976423    KYM88871.1    GFDF01010198    JAV03886.1    CH916367    EDW00602.1    GFDF01009932    JAV04152.1    KQ981071    KYN09805.1    UFQS01003417    UFQT01003417    SSX15625.1    SSX34986.1    NNAY01002784    OXU20569.1    CH963857    EDW76663.1    KQ761221    OAD57966.1    CH940648    EDW60352.1    KQ983012    KYQ48253.1    CP012524    ALC41855.1    GBBI01001504    JAC17208.1    PYGN01001565    PSN34019.1    QOIP01000002    RLU25459.1    GEDC01018875    GEDC01014921    JAS18423.1    JAS22377.1    GBBM01002386    JAC33032.1    LSMT01000386    PFX18909.1    GEFM01001178    JAP74618.1    RCHS01000623    RMX57717.1    NOWV01000046    RDD42920.1    DS985244    EDV25354.1    GADI01006712    JAA67096.1    GEZM01020062    JAV89425.1    OUUW01000006    SPP82376.1    AFYH01057556    AFYH01057557    KQ434785    KZC04999.1    GFPF01011103    MAA22249.1    KQ971321    EFA00625.1   

Proteomes

UP000005204    UP000283053    UP000053240    UP000053268    UP000007151    UP000008820    + More
UP000075883    UP000002320    UP000030765    UP000075885    UP000069272    UP000000673    UP000075920    UP000075902    UP000076407    UP000007062    UP000075840    UP000075900    UP000075882    UP000075886    UP000075881    UP000076408    UP000075903    UP000037510    UP000092462    UP000027135    UP000075884    UP000005203    UP000095300    UP000095301    UP000242457    UP000015102    UP000009192    UP000014760    UP000037069    UP000092444    UP000183832    UP000092445    UP000078200    UP000192221    UP000092460    UP000007801    UP000092443    UP000092461    UP000283509    UP000078541    UP000053105    UP000005205    UP000078540    UP000001070    UP000078492    UP000215335    UP000007798    UP000085678    UP000008792    UP000002358    UP000075809    UP000092553    UP000245037    UP000279307    UP000225706    UP000275408    UP000253843    UP000009022    UP000268350    UP000008672    UP000076502    UP000189705    UP000007266   

PRIDE

H9JR32   

Pfam

PF13847   Methyltransf_31        + More
PF01873   eIF-5_eIF-2B

Interpro

IPR025714   Methyltranfer_dom        + More
IPR029063   SAM-dependent_MTases       
IPR026635   Efm4/METTL10       
IPR001310   Histidine_triad_HIT       
IPR011146   HIT-like       
IPR036265   HIT-like_sf       
IPR016190   Transl_init_fac_IF2/IF5_Zn-bd       
IPR016189   Transl_init_fac_IF2/IF5_N       
IPR002735   Transl_init_fac_IF2/IF5       

SUPFAM

SSF53335   SSF53335        + More
SSF54197   SSF54197       
SSF75689   SSF75689       
SSF100966   SSF100966       

Gene 3D

3.30.428.10    

ProteinModelPortal

H9JR32   A0A2W1BJR8   A0A2H1W911   A0A3S2LYV6   A0A0N1IH50   A0A194Q3M5   + More
A0A212FHA5   S4PWS0   Q17PM4   A0A023ELE3   A0A1Q3FA79   A0A182M0T4   A0A2M4BZ46   A0A2M4BZ68   A0A2M4BYY1   A0A2M4BZ00   B0WIK4   A0A084W496   A0A2M4AX98   A0A182PHP5   A0A182FPB3   W5JKD9   A0A182WIG3   A0A182TYF4   A0A182XMU9   Q7Q6T8   A0A182HWQ6   A0A182RIG9   A0A182LJ17   A0A182QDJ8   A0A182K278   A0A182Y1B9   A0A182VC46   A0A0L7L229   A0A1B0CZP0   A0A067QSZ5   A0A182NGY3   A0A087ZU12   A0A1I8PET5   A0A0A9WG81   A0A1I8MQF2   A0A2A3EJ95   T1GUJ9   B4KM11   R7V743   A0A1B6KAE0   A0A0L0BWP3   A0A1B0FKT4   A0A1J1HI76   A0A1A9Z697   A0A1A9VU02   A0A034WN47   A0A0A1XEG3   A0A1W4UUA0   A0A1B0AUB6   B3MLC2   A0A1B6E826   A0A1A9XD40   A0A0K8UVN7   A0A1B0CSL2   A0A3R7QI16   A0A1B6BZS1   E9IFZ1   W8BQ09   A0A195FHI7   A0A0M9AB85   A0A158NY75   A0A195BQM3   A0A1L8DBP8   B4J4Q6   A0A1L8DCH0   A0A151ISE3   A0A336LGD4   A0A232EQ97   B4MX24   A0A1S3H7F8   A0A310SLJ6   B4LQ29   K7J6F5   A0A151WK47   A0A0M4EKE7   A0A023F7J2   A0A2P8XPT3   A0A3L8DZV5   A0A1B6D9L9   A0A023GGG7   A0A2B4RQ29   A0A131Y7Z4   A0A3M6UVS4   A0A369S7W7   B3RUN0   A0A0K8R7P6   A0A1Y1MYF7   A0A3B0K9Q2   H3B1B8   A0A154NZ95   A0A1U7S5N0   A0A1S3HCX4   A0A224Z2R2   D6WH31  

PDB

2PXX     E-value=5.17345e-06,     Score=116

KEGG

101736309    K22856 EEF1A lysine methyltransferase 2 [EC:2.1.1.-] | (RefSeq) protein-lysine N-methyltransferase M

GO

GO:0005737   GO:0016279   GO:0008168   GO:0018027   GO:0018026   GO:0003743   GO:0005634   GO:0051726   GO:0046872   GO:0004659   GO:0006744   GO:0016627   GO:0030145   GO:0015923   GO:0006260  

Subcellular location

Cytoplasm  
Nucleus  

Length:

215

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04888

Exp number, first 60 AAs:

0

Total prob of N-in:

0.03591

outside

1  -  215

 

 

Pi

286.040199

Theta

189.389709

Tajima's D

1.076126

CLR

0.191846

CSRT

0.68271586420679

Interpretation

Uncertain