Gene

KWMTBOMO06277

Annotation

PREDICTED:_ras-related_protein_Rab-24-like_[Plutella_xylostella]

Location

Bomo_Chr11(+):3722336-3723388      View in EpiBrowser

Full name

Ras-related protein Rab-24      

Location in the cell

Extracellular   Reliability : 1.563

CDS

ATGAGTCGATGTGATTTTAAAATAGTGCTTTTAGGCAGCGAACACGTCGGAAAGACGAGCTTAGTTTTAAGATTCGTGAATTGTAGGTTCAACGCTGAGATACCATATCAAAATACCGTCGGTGCTGCATTTTGCGCTAAAGCTATGCGATCAAAAGAAAAAGACTACAGTATTGGCATCTGGGATACAGCAGGCAGCGAAAGGTATATTAATAATTATGTACATTGTATATAG

Protein

MSRCDFKIVLLGSEHVGKTSLVLRFVNCRFNAEIPYQNTVGAAFCAKAMRSKEKDYSIGIWDTAGSERYINNYVHCI

Description

May be involved in autophagy-related processes.

Subunit

Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB. Interacts with ZFYVE20.

Miscellaneous

The unusual Ser-67, instead of a conserved Gln in other family members, is the cause of low GTPase activity. As a result, the predominant nucleotide associated with the protein is GTP (By similarity).

Similarity

Belongs to the small GTPase superfamily. Rab family.

Keywords

Autophagy   Complete proteome   Cytoplasm   GTP-binding   Lipoprotein   Membrane   Nucleotide-binding   Prenylation   Protein transport   Reference proteome   Transport  

Feature

chain  Ras-related protein Rab-24

Uniprot

A0A194Q4D6   A0A0N0PEA2   A0A2H1V5D4   A0A2A4JQQ2   A0A1E1WRL3   A0A212F0Y1   + More
A0A2J7PQN6   A0A2P8Y430   K7J6I0   A0A232ESN9   A0A0M8ZZ71   A0A2A3EER8   A0A088A4K1   A0A154PKK7   T2M8J9   A0A2Y9QSA9   A0A2Y9EJM7   E1B771   A0A3Q1M6P8   L9JBN8   A0A0L7QMM0   A0A1A6GHY1   C3Y491   A0A061IBW5   A0A067RHX9   A0A1Z5KWR4   W4Z213   A0A2R5L465   L7LUG3   A0A023FUW3   A0A293LBI9   A0A224Z5J3   A0A131Z646   L7M734   A0A224Z7H1   G3ML32   A0A023GFU7   A0A1E1WZF1   A0A131XJP9   A0A2B4RZB2   A0A026WAD7   A0A2Y9QLB7   A0A2Y9QFV8   A0A0K8R8Z2   A0A3Q7TLT2   A0A2Y9HZA2   A0A2U3ZGP9   A0A3Q7U4M6   U6DW12   A0A3Q7NN36   A0A2Y9HZQ3   A0A091DUX7   F6V5H3   A0A384C7V0   A0A3Q7NNG3   A0A2Y9HZA6   A0A3Q7WY86   L5JV16   A0A384C6T0   A0A3Q7XUM0   G1TK72   A0A1S3IJZ8   H0XQF3   D2HZ82   B7PLK7   V9L127   A0A250XW42   A0A2U3XPB0   G1Q6N8   K9IWQ8   A0A2K5RMM0   Q3T107   A0A2K6ARW3   A0A2K6LR30   A0A384C6V1   G1RQA7   A0A2K5YTH6   A0A0D9R986   A0A2R9BW20   A0A096MWW9   A0A2K5MWH9   A0A2U3W0R9   A0A2K5I1Z0   A0A3Q7W102   G7P700   G3RS69   H2QS35   G7MU36   Q969Q5   I3MWQ8   E2R4M1   F6XZH4   A0A2Y9DBD6   A0A3Q7NWZ5   A0A2K5CR06   A0A2Y9HZ97   A0A2U3XP12   A0A2I2UYV4   L5LY47   A0A3Q7T1R8  

Pubmed

26354079    22118469    29403074    20075255    28648823    24065732    + More
19393038    23385571    18563158    23929341    24845553    28528879    25576852    28797301    26830274    22216098    28503490    28049606    24508170    30249741    17495919    23258410    24813606    21993624    20010809    24402279    28087693    22722832    22002653    22398555    16136131    17431167    25319552    15489334    17974005    10660536    16034420    21269460    16341006    19892987    17975172   

EMBL

KQ459463    KPJ00403.1    KQ459891    KPJ19549.1    ODYU01000740    SOQ35986.1    + More
NWSH01000758    PCG74385.1    GDQN01001613    JAT89441.1    AGBW02011017    OWR47364.1    NEVH01022635    PNF18642.1    PYGN01000952    PSN39005.1    NNAY01002393    OXU21371.1    KQ435803    KOX73086.1    KZ288266    PBC30255.1    KQ434948    KZC12399.1    HAAD01002028    CDG68260.1    KB321078    ELW47980.1    KQ414885    KOC59873.1    LZPO01096785    OBS65479.1    GG666484    EEN65117.1    KE671212    ERE80482.1    KK852669    KDR18847.1    GFJQ02007408    JAV99561.1    AAGJ04055392    AAGJ04055393    AAGJ04055394    GGLE01000162    MBY04288.1    GACK01010550    JAA54484.1    GBBL01002041    JAC25279.1    GFWV01000421    MAA25151.1    GFPF01011225    MAA22371.1    GEDV01002295    JAP86262.1    GACK01006066    JAA58968.1    GFPF01011224    MAA22370.1    JO842583    AEO34200.1    GBBM01002641    JAC32777.1    GFAC01006788    JAT92400.1    GEFH01002231    JAP66350.1    LSMT01000196    PFX23794.1    KK107323    QOIP01000002    EZA52596.1    RLU25573.1    GADI01006455    JAA67353.1    HAAF01014859    CCP86681.1    KN122016    KFO34090.1    KB031114    ELK03150.1    AAGW02066612    AAQR03181150    ACTA01043487    GL193783    EFB17690.1    ABJB010113239    ABJB010182785    ABJB010332394    ABJB010489088    ABJB010645540    ABJB010782999    ABJB010924951    ABJB010970624    ABJB011038339    ABJB011073917    DS740966    EEC07479.1    JW872065    AFP04583.1    GFFV01004352    JAV35593.1    AAPE02001259    GABZ01007979    JAA45546.1    BC102183    AAI02184.1    ADFV01124990    AQIB01152928    AJFE02019372    AHZZ02030477    AQIA01061548    CM001281    EHH54796.1    CABD030042611    AACZ04060243    GABC01001087    GABC01001086    GABF01001862    GABF01001861    GABD01008146    GABD01008145    GABE01010897    GABE01010896    NBAG03000516    JAA10251.1    JAA20283.1    JAA24954.1    JAA33842.1    PNI18094.1    PNI18095.1    JSUE03037611    JU319791    JU472881    JU476042    JU476043    JV047403    JV047404    CM001258    AFE63547.1    AFH29685.1    AFI37474.1    EHH27076.1    AF087904    BT007268    CH471195    BC010006    BC015534    BC021263    AL833898    AGTP01071708    AAEX03002967    AANG04001174    KB106582    ELK30950.1   

Proteomes

UP000053268    UP000053240    UP000218220    UP000007151    UP000235965    UP000245037    + More
UP000002358    UP000215335    UP000053105    UP000242457    UP000005203    UP000076502    UP000248480    UP000248484    UP000009136    UP000011518    UP000053825    UP000092124    UP000001554    UP000030759    UP000027135    UP000007110    UP000225706    UP000053097    UP000279307    UP000286640    UP000248481    UP000245340    UP000286641    UP000028990    UP000002280    UP000261680    UP000286642    UP000010552    UP000291021    UP000001811    UP000085678    UP000005225    UP000008912    UP000001555    UP000245341    UP000001074    UP000233040    UP000233120    UP000233180    UP000001073    UP000233140    UP000029965    UP000240080    UP000028761    UP000233060    UP000233080    UP000009130    UP000233100    UP000001519    UP000002277    UP000006718    UP000005640    UP000005215    UP000002254    UP000002281    UP000233020    UP000011712   

PRIDE

Q969Q5   

Pfam

PF00071   Ras

Interpro

IPR001806   Small_GTPase        + More
IPR027417   P-loop_NTPase       
IPR005225   Small_GTP-bd_dom       
IPR041828   Rab24       

SUPFAM

SSF52540   SSF52540       

CDD

cd04118  Rab24

ProteinModelPortal

A0A194Q4D6   A0A0N0PEA2   A0A2H1V5D4   A0A2A4JQQ2   A0A1E1WRL3   A0A212F0Y1   + More
A0A2J7PQN6   A0A2P8Y430   K7J6I0   A0A232ESN9   A0A0M8ZZ71   A0A2A3EER8   A0A088A4K1   A0A154PKK7   T2M8J9   A0A2Y9QSA9   A0A2Y9EJM7   E1B771   A0A3Q1M6P8   L9JBN8   A0A0L7QMM0   A0A1A6GHY1   C3Y491   A0A061IBW5   A0A067RHX9   A0A1Z5KWR4   W4Z213   A0A2R5L465   L7LUG3   A0A023FUW3   A0A293LBI9   A0A224Z5J3   A0A131Z646   L7M734   A0A224Z7H1   G3ML32   A0A023GFU7   A0A1E1WZF1   A0A131XJP9   A0A2B4RZB2   A0A026WAD7   A0A2Y9QLB7   A0A2Y9QFV8   A0A0K8R8Z2   A0A3Q7TLT2   A0A2Y9HZA2   A0A2U3ZGP9   A0A3Q7U4M6   U6DW12   A0A3Q7NN36   A0A2Y9HZQ3   A0A091DUX7   F6V5H3   A0A384C7V0   A0A3Q7NNG3   A0A2Y9HZA6   A0A3Q7WY86   L5JV16   A0A384C6T0   A0A3Q7XUM0   G1TK72   A0A1S3IJZ8   H0XQF3   D2HZ82   B7PLK7   V9L127   A0A250XW42   A0A2U3XPB0   G1Q6N8   K9IWQ8   A0A2K5RMM0   Q3T107   A0A2K6ARW3   A0A2K6LR30   A0A384C6V1   G1RQA7   A0A2K5YTH6   A0A0D9R986   A0A2R9BW20   A0A096MWW9   A0A2K5MWH9   A0A2U3W0R9   A0A2K5I1Z0   A0A3Q7W102   G7P700   G3RS69   H2QS35   G7MU36   Q969Q5   I3MWQ8   E2R4M1   F6XZH4   A0A2Y9DBD6   A0A3Q7NWZ5   A0A2K5CR06   A0A2Y9HZ97   A0A2U3XP12   A0A2I2UYV4   L5LY47   A0A3Q7T1R8  

PDB

2HEI     E-value=5.03565e-11,     Score=156

KEGG

101745412    K07912 Ras-related protein Rab-24 | (RefSeq) ras-related protein Rab-24-like

GO

GO:0005525   GO:0003924   GO:0005776   GO:0032482   GO:0005768   GO:0030139   GO:0006886   GO:0030667   GO:0006914   GO:0005886   GO:0043312   GO:0005829   GO:0007264   GO:0003676   GO:0016787   GO:0008235   GO:0019538   GO:0030145   GO:0015923   GO:0005634   GO:0006260  

Subcellular location

Cytoplasm   Only about 20-25% is recovered in the particulate fraction.   With evidence from 2 publications.
Cytosol   Only about 20-25% is recovered in the particulate fraction.   With evidence from 2 publications.
Membrane   Only about 20-25% is recovered in the particulate fraction.   With evidence from 2 publications.

Length:

77

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00394

Exp number, first 60 AAs:

0.00384

Total prob of N-in:

0.32566

outside

1  -  77

 

 

Pi

212.12786

Theta

184.939799

Tajima's D

0.462591

CLR

59.982732

CSRT

0.499675016249188

Interpretation

Uncertain