Silkworm Genome Informatics Database

Gene

KWMTBOMO06232 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001801

Annotation

Uncharacterized_protein_OBRU01_01903_[Operophtera_brumata]

Location

Bomo_Chr11(+):3039935-3044032 View in EpiBrowser

Full name

RuvB-like helicase

Location in the cell

Cytoplasmic Reliability : 1.329 Nuclear Reliability : 1.543

CDS

ATGGAAGACGTGAAAAAGGTCTACTCGCTGTTCTTGGACGAGCATCGTTCCGAGCAGTTTTTGAAGGAGTACCAGGACGAGTTTATGTTTAACGATGGTTCCGGCGATGCATCGCAAGTGATGATGGAAGTATCTCAAAATTTACTTCGCGCTAACAACCAAATCTTTAAGAATGTCGCCCAACAAAGGAACATGAGCGTTATCTGCACTCCGCCAAGAAACAAGGTTTCCAGAGGTGAGATGATCTTCCTCGCCGGCCTGATGGTGGTGGGCTGGTCTGCCATCCCAGCCTGGGTGTTGGTCAATATCAAGCATTACCGCGACAAGCAATAA

Protein

MEDVKKVYSLFLDEHRSEQFLKEYQDEFMFNDGSGDASQVMMEVSQNLLRANNQIFKNVAQQRNMSVICTPPRNKVSRGEMIFLAGLMVVGWSAIPAWVLVNIKHYRDKQ

Description

Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate

Similarity

Belongs to the RuvB family.

Uniprot

A0A0N0PEM8 A0A3Q3LF31

EC Number

3.6.4.12

Pubmed

26354079

EMBL

KQ459757 KPJ20146.1

Proteomes

UP000053240 UP000261640

Pfam

PF06068 TIP49 + More
PF17856 TIP49_C

Interpro

IPR003205   Cyt_c_oxidase_su8        + More
IPR010339   TIP49_P-loop
IPR027238   RuvB-like
IPR027417   P-loop_NTPase
IPR037942   RUVBL2
IPR003593   AAA+_ATPase
IPR041048   RuvB-like_C

SUPFAM

SSF52540 SSF52540

ProteinModelPortal

A0A0N0PEM8 A0A3Q3LF31

PDB

3UK6 E-value=4.68517e-09, Score=139

KEGG

101741939 K02273 cytochrome c oxidase subunit 8 | (RefSeq) uncharacterized LOC101741939

PATHWAY

00190 Oxidative phosphorylation - Bombyx mori (domestic silkworm)
01100 Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021 GO:0006310 GO:0004386 GO:0006281 GO:0005524 GO:0005634 GO:0004129 GO:0006412 GO:0016020 GO:0022857 GO:0004559 GO:0006013 GO:0015923 GO:0006260

PANTHER

PTHR16717 PTHR11093:SF2 PTHR11093

Subcellular location

Nucleus

Length:

110

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

21.87819

Exp number, first 60 AAs:

0.00015

Total prob of N-in:

0.23811

outside

1 - 80

TMhelix

81 - 103

inside

104 - 110

Pi

222.255046

Theta

143.266381

Tajima's D

0.855103

CLR

10.01176

CSRT

0.621568921553922

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics