Gene
KWMTBOMO06214
Pre Gene Modal
BGIBMGA001651
Annotation
PREDICTED:_PBAN-type_neuropeptides_isoform_X1_[Bombyx_mori]
Full name
PBAN-type neuropeptides
Alternative Name
Neo-PBAN
Pheromone/pyrokinin biosynthesis-activating neuropeptide
Pheromone/pyrokinin biosynthesis-activating neuropeptide
Location in the cell
Extracellular Reliability : 1.244 Mitochondrial Reliability : 1.279 Nuclear Reliability : 1.17
Sequence
CDS
ATGTATAAAACCAACATTGTTTTCAACGTTTTAGCTTTGGCATTGTTCAGTATTTTCTTCGCGAGTTGCACGGATATGAAGGATGAAAGCGACAGAGGAGCTCACAGTGAGCGGGGCGCTCTCTGGTTCGGCCCCAGACTCGGGAAGCGATCAATGAAGCCATCCACTGAAGATAACAGGCAAACCTTCCTGAGGCTGCTCGAGGCGGCTGATGCCCTCAAATTTTACTACGACCAGCTACCTTACGAGAGGCAAGCCGATGAACCGGAAACCAAAGTAACAAAGAAGATCATCTTCACCCCCAAACTCGGGAGGAGCGTCGCCAAACCCCAGACGCATGAAAGCCTCGAATTCATCCCCCGGCTCGGAAGGCGGCTCTCTGAGGACATGCCTGCTACGCCAGCTGACCAGGAAATGTACCAACCTGACCCCGAAGAAATGGAGTCAAGAACAAGATACTTCTCGCCCAGGCTGGGGCGCACCATGAGCTTTTCGCCCAGACTGGGAAGGGAGCTTTCGTACGATTACCCTACAAAATATAGGGTTGCCAGAAGCGTTAACAAGACAATGGACAACTAA
Protein
MYKTNIVFNVLALALFSIFFASCTDMKDESDRGAHSERGALWFGPRLGKRSMKPSTEDNRQTFLRLLEAADALKFYYDQLPYERQADEPETKVTKKIIFTPKLGRSVAKPQTHESLEFIPRLGRRLSEDMPATPADQEMYQPDPEEMESRTRYFSPRLGRTMSFSPRLGRELSYDYPTKYRVARSVNKTMDN
Summary
Description
A hormone that controls sex pheromone production in females and pheromone responsiveness in male. Also mediates visceral muscle contractile activity (myotropic activity). Identical to MRCH which is implicated in the formation of both melanin in the cuticle and ommochrome in the epidermis of armyworm species.
Diapause hormone (DH) is responsible for induction of embryonic diapause.
The three SGNPS are far less active than DH in inducing diapause eggs. Beta-SGNP expressed higher pban activity than PBAN-I, but alpha- and gamma-SGNP were far less active in pheromonotropic activity.
A hormone that controls sex pheromone production in females and pheromone responsiveness in male.
A hormone that controls sex pheromone production in females and pheromone responsiveness in male. Also mediates visceral muscle contractile activity (myotropic activity).
Pheromone biosynthesis-activating neuropeptide: A hormone that controls sex pheromone production in female moths and pheromone responsiveness in male (PubMed:9753769).
A hormone that controls sex pheromone production in females and pheromone responsiveness in male. Also mediates visceral muscle contractile activity (myotropic activity) (By similarity).
Pyrokinins mediate visceral muscle contractile activity (myotropic activity).
Diapause hormone (DH) is responsible for induction of embryonic diapause.
The three SGNPS are far less active than DH in inducing diapause eggs. Beta-SGNP expressed higher pban activity than PBAN-I, but alpha- and gamma-SGNP were far less active in pheromonotropic activity.
A hormone that controls sex pheromone production in females and pheromone responsiveness in male.
A hormone that controls sex pheromone production in females and pheromone responsiveness in male. Also mediates visceral muscle contractile activity (myotropic activity).
Pheromone biosynthesis-activating neuropeptide: A hormone that controls sex pheromone production in female moths and pheromone responsiveness in male (PubMed:9753769).
A hormone that controls sex pheromone production in females and pheromone responsiveness in male. Also mediates visceral muscle contractile activity (myotropic activity) (By similarity).
Pyrokinins mediate visceral muscle contractile activity (myotropic activity).
Miscellaneous
Juvenile hormone seems to allow PBAN release, which then induces pheromone biosynthesis.
PBAN is produced independent of the photoperiod. The circadian rhythm in pheromone production is due to the circadian rhythm of PBAN release.
The structural similarity of PK1 and PK2 to CAPA-PK might compensate for the apparent absence of CAPA-PK in ants.
PBAN is produced independent of the photoperiod. The circadian rhythm in pheromone production is due to the circadian rhythm of PBAN release.
The structural similarity of PK1 and PK2 to CAPA-PK might compensate for the apparent absence of CAPA-PK in ants.
Similarity
Belongs to the pyrokinin family.
Keywords
Amidation
Cleavage on pair of basic residues
Complete proteome
Direct protein sequencing
Hormone
Neuropeptide
Polymorphism
Reference proteome
Secreted
Signal
Pheromone response
Feature
peptide Diapause hormone
Uniprot
P09971
H9IWL9
Q6SYA3
C0HL17
Q7Z1Z5
Q95UR4
+ More
O18641 P11159 Q6TY85 A0A0D4D9X6 Q8MZU7 A0A385H8Z8 A0A0N7DI91 Q95P48 O76818 A0A0A7F176 Q6E0C7 Q86QR0 Q6RKA1 A5Z1Y5 Q1JU71 Q86QQ2 O45027 J7H3E4 A0A2A4JGG8 A0A1W5PQJ5 A0A1P7ZJD1 A0A1W5PQE2 A0A1W5PQG7 A0A1W5PQF6 A0A1W5PQF1 A0A1W5PQK5 M9P2L6 A0A2R4PCU7 A0A2W1B9W5 A6BMD6 G5CV05 Q2M4G0 Q962Y7 A0A212ES58 A0A0S1U1T0 B0WFD4 A0A1Q3FSW7 Q16N80 A0A182VCE8 A0A182ULA4 A0A2K7P6D2 A0A182IS14 A0A182XLX5 A0A182LQB1 A0A182HS26 Q7PTL2 A0A182SNW0 A0A182GE53 A0A182H4T8 A0A182W2L1 A0A182QMN8 A0A182MPR7 A0A182NG82 A0A182PEH8 D6W7C9 A0A084W9G1 A0A182XVD3 A0A182R7L7 W5JTV4 A0A182FPZ0 A0A2J7PXH4 N6TNL6 C3TWQ8 D8VD46 D8VD45 D8VD44 E2AFK9 A0A226ERT0 D8VD42 D8VD43 A0A0C9Q7J7 U5EYW3
O18641 P11159 Q6TY85 A0A0D4D9X6 Q8MZU7 A0A385H8Z8 A0A0N7DI91 Q95P48 O76818 A0A0A7F176 Q6E0C7 Q86QR0 Q6RKA1 A5Z1Y5 Q1JU71 Q86QQ2 O45027 J7H3E4 A0A2A4JGG8 A0A1W5PQJ5 A0A1P7ZJD1 A0A1W5PQE2 A0A1W5PQG7 A0A1W5PQF6 A0A1W5PQF1 A0A1W5PQK5 M9P2L6 A0A2R4PCU7 A0A2W1B9W5 A6BMD6 G5CV05 Q2M4G0 Q962Y7 A0A212ES58 A0A0S1U1T0 B0WFD4 A0A1Q3FSW7 Q16N80 A0A182VCE8 A0A182ULA4 A0A2K7P6D2 A0A182IS14 A0A182XLX5 A0A182LQB1 A0A182HS26 Q7PTL2 A0A182SNW0 A0A182GE53 A0A182H4T8 A0A182W2L1 A0A182QMN8 A0A182MPR7 A0A182NG82 A0A182PEH8 D6W7C9 A0A084W9G1 A0A182XVD3 A0A182R7L7 W5JTV4 A0A182FPZ0 A0A2J7PXH4 N6TNL6 C3TWQ8 D8VD46 D8VD45 D8VD44 E2AFK9 A0A226ERT0 D8VD42 D8VD43 A0A0C9Q7J7 U5EYW3
Pubmed
1280417
8475067
7893764
9362122
1368584
2775285
+ More
8512566 3896851 19121390 16675043 28502715 15670862 15037090 9807222 8022813 17802237 8791159 15777675 30171635 12110297 9753769 29466015 15245868 17967345 12974956 9684333 28756777 17368196 16005110 15350612 22118469 17510324 20966253 12364791 26483478 18362917 19820115 24438588 25244985 20920257 23761445 23537049 19320757 20513055 20798317 25641051
8512566 3896851 19121390 16675043 28502715 15670862 15037090 9807222 8022813 17802237 8791159 15777675 30171635 12110297 9753769 29466015 15245868 17967345 12974956 9684333 28756777 17368196 16005110 15350612 22118469 17510324 20966253 12364791 26483478 18362917 19820115 24438588 25244985 20920257 23761445 23537049 19320757 20513055 20798317 25641051
EMBL
S50045
D28810
D13437
D16230
D28764
BABH01021195
+ More
AY445658 AAR17699.1 AY286544 AAP41132.1 AY043222 AAL05596.1 U96761 AY052417 U08109 AY382615 AAQ82626.1 KJ205531 AJT60314.1 AF492474 AAM43840.1 MH028120 AXY04289.1 KP006328 AKT95050.1 AF401480 AAK84160.1 AJ009674 KP027544 AIY72749.1 AY628764 AAT64424.1 AY172672 AAO18192.1 AY495967 AAR87744.1 EF614262 ABR04093.1 AB259122 BAE94185.1 AY173075 AAO20095.1 AF044079 JX195641 AFP87384.1 NWSH01001463 PCG71167.1 KU952096 AOY34010.1 KT588300 AMB57367.1 KU952097 KU952098 KU952099 KU952100 KU952101 KU952103 KU952104 KU952105 KU952109 KU952110 KU952111 AOY34011.1 AOY34014.1 AOY34017.1 KU952102 KU952108 KU952112 KU952113 AOY34016.1 AOY34027.1 KU952114 AOY34028.1 KU952107 AOY34021.1 KU952106 AOY34020.1 JQ901962 JX412479 AFX71575.1 AGI96545.1 KY987647 AVX48909.1 KZ150374 PZC71125.1 AB308061 BAF64458.1 JN410824 AEP25400.1 AY904342 AAX99220.1 AF395670 AAK72980.1 AGBW02012872 OWR44299.1 KT005963 ALM30314.1 DS231916 EDS26151.1 GFDL01004479 JAV30566.1 CH477835 EAT35796.1 APCN01000234 AAAB01008799 EAA03729.3 JXUM01057827 KQ561973 KXJ77024.1 JXUM01025636 KQ560729 KXJ81110.1 AXCN02001629 AXCM01000365 KQ971307 EFA11568.2 ATLV01021756 KE525322 KFB46855.1 ADMH02000156 ETN67561.1 NEVH01020859 PNF21014.1 APGK01057891 KB741282 KB632052 ENN70850.1 ERL88321.1 FJ223176 ACL35348.1 GQ872201 ADI88482.1 GQ872200 ADI88481.1 GQ872199 ADI88480.1 GL439118 EFN67760.1 LNIX01000002 OXA59867.1 GQ872197 ADI88478.1 GQ872198 ADI88479.1 GBYB01010148 JAG79915.1 GANO01000025 JAB59846.1
AY445658 AAR17699.1 AY286544 AAP41132.1 AY043222 AAL05596.1 U96761 AY052417 U08109 AY382615 AAQ82626.1 KJ205531 AJT60314.1 AF492474 AAM43840.1 MH028120 AXY04289.1 KP006328 AKT95050.1 AF401480 AAK84160.1 AJ009674 KP027544 AIY72749.1 AY628764 AAT64424.1 AY172672 AAO18192.1 AY495967 AAR87744.1 EF614262 ABR04093.1 AB259122 BAE94185.1 AY173075 AAO20095.1 AF044079 JX195641 AFP87384.1 NWSH01001463 PCG71167.1 KU952096 AOY34010.1 KT588300 AMB57367.1 KU952097 KU952098 KU952099 KU952100 KU952101 KU952103 KU952104 KU952105 KU952109 KU952110 KU952111 AOY34011.1 AOY34014.1 AOY34017.1 KU952102 KU952108 KU952112 KU952113 AOY34016.1 AOY34027.1 KU952114 AOY34028.1 KU952107 AOY34021.1 KU952106 AOY34020.1 JQ901962 JX412479 AFX71575.1 AGI96545.1 KY987647 AVX48909.1 KZ150374 PZC71125.1 AB308061 BAF64458.1 JN410824 AEP25400.1 AY904342 AAX99220.1 AF395670 AAK72980.1 AGBW02012872 OWR44299.1 KT005963 ALM30314.1 DS231916 EDS26151.1 GFDL01004479 JAV30566.1 CH477835 EAT35796.1 APCN01000234 AAAB01008799 EAA03729.3 JXUM01057827 KQ561973 KXJ77024.1 JXUM01025636 KQ560729 KXJ81110.1 AXCN02001629 AXCM01000365 KQ971307 EFA11568.2 ATLV01021756 KE525322 KFB46855.1 ADMH02000156 ETN67561.1 NEVH01020859 PNF21014.1 APGK01057891 KB741282 KB632052 ENN70850.1 ERL88321.1 FJ223176 ACL35348.1 GQ872201 ADI88482.1 GQ872200 ADI88481.1 GQ872199 ADI88480.1 GL439118 EFN67760.1 LNIX01000002 OXA59867.1 GQ872197 ADI88478.1 GQ872198 ADI88479.1 GBYB01010148 JAG79915.1 GANO01000025 JAB59846.1
Proteomes
UP000005204
UP000218220
UP000007151
UP000002320
UP000008820
UP000075903
+ More
UP000075902 UP000075880 UP000076407 UP000075882 UP000075840 UP000007062 UP000075901 UP000069940 UP000249989 UP000075920 UP000075886 UP000075883 UP000075884 UP000075885 UP000007266 UP000030765 UP000076408 UP000075900 UP000000673 UP000069272 UP000235965 UP000019118 UP000030742 UP000000311 UP000198287
UP000075902 UP000075880 UP000076407 UP000075882 UP000075840 UP000007062 UP000075901 UP000069940 UP000249989 UP000075920 UP000075886 UP000075883 UP000075884 UP000075885 UP000007266 UP000030765 UP000076408 UP000075900 UP000000673 UP000069272 UP000235965 UP000019118 UP000030742 UP000000311 UP000198287
Pfam
PF05874 PBAN
ProteinModelPortal
P09971
H9IWL9
Q6SYA3
C0HL17
Q7Z1Z5
Q95UR4
+ More
O18641 P11159 Q6TY85 A0A0D4D9X6 Q8MZU7 A0A385H8Z8 A0A0N7DI91 Q95P48 O76818 A0A0A7F176 Q6E0C7 Q86QR0 Q6RKA1 A5Z1Y5 Q1JU71 Q86QQ2 O45027 J7H3E4 A0A2A4JGG8 A0A1W5PQJ5 A0A1P7ZJD1 A0A1W5PQE2 A0A1W5PQG7 A0A1W5PQF6 A0A1W5PQF1 A0A1W5PQK5 M9P2L6 A0A2R4PCU7 A0A2W1B9W5 A6BMD6 G5CV05 Q2M4G0 Q962Y7 A0A212ES58 A0A0S1U1T0 B0WFD4 A0A1Q3FSW7 Q16N80 A0A182VCE8 A0A182ULA4 A0A2K7P6D2 A0A182IS14 A0A182XLX5 A0A182LQB1 A0A182HS26 Q7PTL2 A0A182SNW0 A0A182GE53 A0A182H4T8 A0A182W2L1 A0A182QMN8 A0A182MPR7 A0A182NG82 A0A182PEH8 D6W7C9 A0A084W9G1 A0A182XVD3 A0A182R7L7 W5JTV4 A0A182FPZ0 A0A2J7PXH4 N6TNL6 C3TWQ8 D8VD46 D8VD45 D8VD44 E2AFK9 A0A226ERT0 D8VD42 D8VD43 A0A0C9Q7J7 U5EYW3
O18641 P11159 Q6TY85 A0A0D4D9X6 Q8MZU7 A0A385H8Z8 A0A0N7DI91 Q95P48 O76818 A0A0A7F176 Q6E0C7 Q86QR0 Q6RKA1 A5Z1Y5 Q1JU71 Q86QQ2 O45027 J7H3E4 A0A2A4JGG8 A0A1W5PQJ5 A0A1P7ZJD1 A0A1W5PQE2 A0A1W5PQG7 A0A1W5PQF6 A0A1W5PQF1 A0A1W5PQK5 M9P2L6 A0A2R4PCU7 A0A2W1B9W5 A6BMD6 G5CV05 Q2M4G0 Q962Y7 A0A212ES58 A0A0S1U1T0 B0WFD4 A0A1Q3FSW7 Q16N80 A0A182VCE8 A0A182ULA4 A0A2K7P6D2 A0A182IS14 A0A182XLX5 A0A182LQB1 A0A182HS26 Q7PTL2 A0A182SNW0 A0A182GE53 A0A182H4T8 A0A182W2L1 A0A182QMN8 A0A182MPR7 A0A182NG82 A0A182PEH8 D6W7C9 A0A084W9G1 A0A182XVD3 A0A182R7L7 W5JTV4 A0A182FPZ0 A0A2J7PXH4 N6TNL6 C3TWQ8 D8VD46 D8VD45 D8VD44 E2AFK9 A0A226ERT0 D8VD42 D8VD43 A0A0C9Q7J7 U5EYW3
Ontologies
GO
Topology
Subcellular location
Secreted
SignalP
Position: 1 - 23,
Likelihood: 0.750411
Length:
192
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
17.8979
Exp number, first 60 AAs:
17.89758
Total prob of N-in:
0.67163
POSSIBLE N-term signal
sequence
inside
1 - 6
TMhelix
7 - 24
outside
25 - 192
Population Genetic Test Statistics
Pi
14.741948
Theta
52.139892
Tajima's D
-1.078402
CLR
208.892825
CSRT
0.121893905304735
Interpretation
Uncertain
