Gene

KWMTBOMO06101

Pre Gene Modal

BGIBMGA001727

Annotation

PREDICTED:_lysosomal_alpha-mannosidase-like_[Bombyx_mori]

Location

Bomo_Chr11(+):416695-421338      View in EpiBrowser

Full name

Alpha-mannosidase      

Location in the cell

PlasmaMembrane   Reliability : 1.7

CDS

ATGGTATACACGCTGCTACGTCAAGGTAGACTCTTTATCGTGGGCGGGGCATGGGGGATGGTGGACGAGGCCACCACCAACTACCACGCCGTGATCGATCAGTTCACGTACTCGCTAAGGAAACTCAACGCTACGTTCCTAGAGTGCGGGCGTCCGCTGATGGCCTGGCAGGCAGATGTCTATGGGCACTCCCGCGAGATCGCCTCGCTGCTGGCCCAGATGGGCTTCGATGGGCTCTTCATAAACCCGATCAGCTTCGACGATGAGCTGGACAGAATGAGGAGGAAATCCATGGAGTTCTTGTGGAGGGGAAGCGATGATTTAGGCGCGGAGACTGATATCTACACCCACAAGCTGTTCGACGGGTACTGGTCTCCGCCAGGGTTCTGCTTCGGGAGCTACTGCGATGACCCCCTCCTCATCACTTCGGACTCAGTCTTCAGAAACATCGACGAGCGGGTCGACCTGTTCATAAAGTCGATCCTCCACCGCCAAGCTCCCTACTACTCCACCAGGAATGTCATGGTGATGATGGGTCAGAGGTTCGGCTACTATGACGCCTCTATATGGTTCGCCAACGTGGATAAATTGATCAACGAAGTGAACAAAAAGAGTTATGAGACCGGAGCCAATATCAATCTGTATTATTCAACGCCGGCGTGCTACCTGAAAGCGGTCTATGACTCCAACCCGACTTTGGACACGAAACAGGATGACTTCTTCCCTATGGCCTACGACAAGTTCTCTCACGCCACCGGCCTGTATACGTCGCGACCCACCATAAAGTACATGGCGAGAGAGGGACATGTATACCTGCAGATGGCCAAGCAGCTTCAGGTCCTCGCCAGACTGTGGAACAACGACCAGCTCTTTGAAGAGTTTCAGTGGGTCATGGGTAATGTTTAG

Protein

MVYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADVYGHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAETDIYTHKLFDGYWSPPGFCFGSYCDDPLLITSDSVFRNIDERVDLFIKSILHRQAPYYSTRNVMVMMGQRFGYYDASIWFANVDKLINEVNKKSYETGANINLYYSTPACYLKAVYDSNPTLDTKQDDFFPMAYDKFSHATGLYTSRPTIKYMAREGHVYLQMAKQLQVLARLWNNDQLFEEFQWVMGNV

Cofactor

Zn(2+)

Similarity

Belongs to the glycosyl hydrolase 38 family.

Feature

chain  Alpha-mannosidase

Uniprot

H9IWU4   A0A2A4JTB7   A0A212F2R7   A0A2A4JU30   A0A2A4JTC5   A0A2W1BD84   + More
E2B6B9   A0A2H1VPQ4   A0A154P4N7   A0A195DWW0   A0A195F0Z8   A0A087ZZ79   B4G755   B3N5F1   A0A151IBC4   A0A158NP11   V5GCU3   A0A3B0JHP2   A0A0J9R086   A0A1W4UUP0   E2ABS8   A0A3G5BIG9   A0A0P8XGR3   Q8IPB7   A0A0Q5WN53   A0A3B0K7V8   A0A3B0JH41   A0A182KEA5   A0A0L7QJS0   Q9VKV1   B3MJI9   A0A0R1DR73   A0A1I8M2X1   B4Q9B2   A0A0A1WZV2   A0A1I8M2X3   A0A336LVA7   A0A336LYZ7   U5EV98   A0A1W4UG04   A0A1A9W6T1   A0A2J7RN15   A0A0K8WDF9   W8APD9   A0A182TAD7   A0A0K8VT60   A0A0K8U3N4   A0A0K8UEK7   A0A0K8VTI9   A0A0A1XEF2   A0A1I8QCY1   A0A026VXZ2   A0A1J1I212   A0A034V6I7   B4LVB7   A0A2J7RN33   B4KHR0   A0A1A9ZH71   A0A1B0B0M4   A0A1Q3FMS6   A0A0Q9XIT5   E9IED8   A0A1Q3FMY3   A0A1I8QD07   A0A1A9XCE3   A0A2H1VKW2   A0A182IPC8   A0A0M4ER29   B4JQ04   A0A1J1I5Z3   A0A2P8ZEB4   B4MUA9   A0A1S4HD42   Q178W0   A0A0M9A0P7   A0A0Q9WJC0   A0A023EWA7   A0A1W4WS90   A0A2A4IXJ1   A0A1S4FBS2   A0A1L8DQQ1   A0A1B0GPJ0   A0A1L8DR39   A0A182MB09   A0A084VFG4   A0A182RK94   A0A182WFL0   A0A1S4GYN8   A0A182VJW0   A0A182GN05   A0A3G5BIM3   A0A182UGZ7   A0A182KMH3   Q5TS83   A0A023EX89   A0A067R124   N6TNX4   W5JQY8  

EC Number

3.2.1.-

Pubmed

19121390    22118469    28756777    20798317    17994087    21347285    + More
22936249    30400621    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    25315136    25830018    24495485    24508170    30249741    25348373    21282665    29403074    12364791    17510324    24945155    24438588    26483478    20966253    24845553    23537049    20920257    23761445   

EMBL

BABH01020972    NWSH01000615    PCG75285.1    AGBW02010691    OWR48030.1    PCG75286.1    + More
PCG75287.1    KZ150423    PZC70926.1    GL445930    EFN88812.1    ODYU01003694    SOQ42778.1    KQ434813    KZC06792.1    KQ980167    KYN17373.1    KQ981891    KYN33784.1    CH479180    EDW28309.1    CH954177    EDV59030.2    KQ978112    KYM96921.1    ADTU01022012    ADTU01022013    ADTU01022014    GALX01000516    JAB67950.1    OUUW01000006    SPP81715.1    CM002910    KMY89556.1    GL438356    EFN69105.1    MK075175    AYV99578.1    CH902620    KPU73915.1    AE014134    AAN10754.1    KQS70602.1    SPP81716.1    SPP81714.1    KQ415041    KOC58867.1    AF145601    AAD38576.1    AAF52958.2    EDV32357.1    CM000157    KRJ97497.1    CM000361    EDX04554.1    KMY89555.1    GBXI01009935    JAD04357.1    UFQS01000218    UFQT01000218    SSX01504.1    SSX21884.1    SSX01503.1    SSX21883.1    GANO01001972    JAB57899.1    NEVH01002545    PNF42230.1    GDHF01003182    JAI49132.1    GAMC01015917    GAMC01015916    GAMC01015915    GAMC01015914    JAB90640.1    GDHF01010271    GDHF01002021    JAI42043.1    JAI50293.1    GDHF01030990    JAI21324.1    GDHF01027225    GDHF01012263    JAI25089.1    JAI40051.1    GDHF01010454    JAI41860.1    GBXI01004996    JAD09296.1    KK107648    QOIP01000008    EZA48346.1    RLU19783.1    CVRI01000038    CRK93802.1    GAKP01021245    JAC37707.1    CH940649    EDW63296.2    PNF42229.1    CH933807    EDW13347.1    JXJN01006781    GFDL01006180    JAV28865.1    KRG03704.1    GL762576    EFZ21090.1    GFDL01006179    JAV28866.1    ODYU01002940    SOQ41072.1    CP012523    ALC39282.1    CH916372    EDV98984.1    CRK93801.1    PYGN01000082    PSN54844.1    CH963857    EDW76035.2    AAAB01008944    CH477358    EAT42739.1    KQ435775    KOX74960.1    KRF81022.1    GAPW01000098    JAC13500.1    NWSH01004815    PCG64677.1    GFDF01005288    JAV08796.1    AJVK01005894    AJVK01005895    GFDF01005289    JAV08795.1    AXCM01004170    ATLV01012389    KE524787    KFB36708.1    JXUM01075505    KQ562889    KXJ74905.1    MK075237    AYV99640.1    EAL40242.3    GAPW01000077    JAC13521.1    KK853110    KDR11229.1    APGK01026882    KB740648    ENN79713.1    ADMH02000752    ETN65164.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000008237    UP000076502    UP000078492    + More
UP000078541    UP000005203    UP000008744    UP000008711    UP000078542    UP000005205    UP000268350    UP000192221    UP000000311    UP000007801    UP000000803    UP000075881    UP000053825    UP000002282    UP000095301    UP000000304    UP000091820    UP000235965    UP000075901    UP000095300    UP000053097    UP000279307    UP000183832    UP000008792    UP000009192    UP000092445    UP000092460    UP000092443    UP000075880    UP000092553    UP000001070    UP000245037    UP000007798    UP000008820    UP000053105    UP000192223    UP000092462    UP000075883    UP000030765    UP000075900    UP000075920    UP000075903    UP000069940    UP000249989    UP000075902    UP000075882    UP000007062    UP000027135    UP000019118    UP000000673   

PRIDE

H9IWU4    Q8IPB7   

Pfam

PF01074   Glyco_hydro_38N        + More
PF17677   Glyco_hydro38C2
PF09261   Alpha-mann_mid
PF07748   Glyco_hydro_38C

Interpro

IPR028995   Glyco_hydro_57/38_cen_sf        + More
IPR027291   Glyco_hydro_38_N_sf       
IPR037094   Glyco_hydro_38_cen_sf       
IPR000602   Glyco_hydro_38_N       
IPR011330   Glyco_hydro/deAcase_b/a-brl       
IPR041147   GH38_C       
IPR015341   Glyco_hydro_38_cen       
IPR011013   Gal_mutarotase_sf_dom       
IPR011682   Glyco_hydro_38_C       
IPR013780   Glyco_hydro_b       

SUPFAM

SSF88688   SSF88688        + More
SSF88713   SSF88713       
SSF74650   SSF74650       

Gene 3D

1.20.1270.50     3.20.110.10     2.60.40.1180    

ProteinModelPortal

H9IWU4   A0A2A4JTB7   A0A212F2R7   A0A2A4JU30   A0A2A4JTC5   A0A2W1BD84   + More
E2B6B9   A0A2H1VPQ4   A0A154P4N7   A0A195DWW0   A0A195F0Z8   A0A087ZZ79   B4G755   B3N5F1   A0A151IBC4   A0A158NP11   V5GCU3   A0A3B0JHP2   A0A0J9R086   A0A1W4UUP0   E2ABS8   A0A3G5BIG9   A0A0P8XGR3   Q8IPB7   A0A0Q5WN53   A0A3B0K7V8   A0A3B0JH41   A0A182KEA5   A0A0L7QJS0   Q9VKV1   B3MJI9   A0A0R1DR73   A0A1I8M2X1   B4Q9B2   A0A0A1WZV2   A0A1I8M2X3   A0A336LVA7   A0A336LYZ7   U5EV98   A0A1W4UG04   A0A1A9W6T1   A0A2J7RN15   A0A0K8WDF9   W8APD9   A0A182TAD7   A0A0K8VT60   A0A0K8U3N4   A0A0K8UEK7   A0A0K8VTI9   A0A0A1XEF2   A0A1I8QCY1   A0A026VXZ2   A0A1J1I212   A0A034V6I7   B4LVB7   A0A2J7RN33   B4KHR0   A0A1A9ZH71   A0A1B0B0M4   A0A1Q3FMS6   A0A0Q9XIT5   E9IED8   A0A1Q3FMY3   A0A1I8QD07   A0A1A9XCE3   A0A2H1VKW2   A0A182IPC8   A0A0M4ER29   B4JQ04   A0A1J1I5Z3   A0A2P8ZEB4   B4MUA9   A0A1S4HD42   Q178W0   A0A0M9A0P7   A0A0Q9WJC0   A0A023EWA7   A0A1W4WS90   A0A2A4IXJ1   A0A1S4FBS2   A0A1L8DQQ1   A0A1B0GPJ0   A0A1L8DR39   A0A182MB09   A0A084VFG4   A0A182RK94   A0A182WFL0   A0A1S4GYN8   A0A182VJW0   A0A182GN05   A0A3G5BIM3   A0A182UGZ7   A0A182KMH3   Q5TS83   A0A023EX89   A0A067R124   N6TNX4   W5JQY8  

PDB

1O7D     E-value=1.71805e-38,     Score=398

KEGG

105841934    K12311 lysosomal alpha-mannosidase [EC:3.2.1.24] | (RefSeq) lysosomal alpha-mannosidase-like

PATHWAY

00511    Other glycan degradation - Bombyx mori (domestic silkworm)
04142    Lysosome - Bombyx mori (domestic silkworm)

GO

GO:0006013   GO:0004559   GO:0030246   GO:0046872   GO:0016021   GO:0004571   GO:0016798   GO:0008152   GO:0005576   GO:0005774   GO:0006517   GO:0004553   GO:0008270   GO:0003824   GO:0005975   GO:0016020   GO:0003677   GO:0000723   GO:0005634   GO:0006260  

Length:

301

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.164310000000001

Exp number, first 60 AAs:

0.11201

Total prob of N-in:

0.04607

outside

1  -  301

 

 

Pi

364.680997

Theta

196.743048

Tajima's D

2.560326

CLR

0.010169

CSRT

0.951402429878506

Interpretation

Uncertain