Gene

KWMTBOMO06100  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001725

Annotation

PREDICTED:_cytoplasmic_aconitate_hydratase-like_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr11(+):340565-405889      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.031

CDS

ATGGCTGGATCCACGAATCCTTACCAGAAGCTGCTGAAGACGATTGAAATTAACGGCTCTACTTACACCTACTACGATGTATCAGCCCTTGGACCTAAATACGATCGTCTCCCGTTCAGCATCAGGGTACTTCTCGAGTCATGCGTGAGGAACTGCGACAACTTCCAGGTCTTGGAGAAGGATGTCAGCAACGTCCTGGACTGGGAGTCGAAGCAGGGCAACGAGGAATCCGTGGAGATCGCCTTCAAACCTGCCAGGGTTATTTTACAGGACCTGACAGGCGTACCAGCGGTGGTAGACTTCGCGGCGATGCGTGACGCCGTGAAGGACCTGGGCGGTGACCCGGACAGGATCAACCCGATATGCCCCGCTGACCTGGTCATAGACCACTCCGTGCAGGTCGACTTCGCGAGGACACCTGACGCTCTGAACAAGAACCAGGACTTGGAGTTCGTGAGGAACAAGGAGAGGTTTCAGTTTCTGAAGTGGGGAGCGCAGGCCTTCGACAACATGCTCATAGTCCCGCCGGGCTCCGGGATCGTGCACCAAGTGAACTTGGAGTACCTGGCGCGCGTGGTGTTCACCGGCCCGCTCCTGCACCCCGACTCCGTGGTCGGCACCGACAGCCACACCACCATGATCAACGGGCTGGGAGTCGTCGGGTGGGGAGTGGGAGGCATCGAGGCGGAAGCCGTGATGCTGGGACAGGCGATCAGCATGCTGCTGCCCAAAGTCGTCGGCTACAAGCTCGTTGGAGAACTGAACCCGTTAGCCACGTCCACCGACCTGGTGCTCACGATAACGAAGCACCTGCGCTCGCTGGGCGTGGTCGGCAAGTTCGTGGAGTTCTTCGGTCCCGGGGTGGGGGCGCTGAGCATCGCCGACCGCGCCACCGTCGCCAACATGTGCCCAGAGTTCGGGGCCACACTGGCGCACTTCCCGGTCGACGCGCGCTCGCTGGAGTACCTGCACCAGACCAACCGTCCCAAAGAGAAGATCGACGTGATCGAATCGTACCTGCGCGCCACGAAGCAGTTCAGGGACTACACCAATCCCGAACAAGATCCCGTGTTCTCAGAGGTGGTGGAGCTGGACCTGGGAGACGTGGTGACGTCCGTGAGCGGGCCCAAGCGGCCCCAGGACCGCGTGTCCGTCGCCATCATGAAGAAGGACTTCCAGGACTGCTTAACCAATAAGGTCGGCTTCAAAGGCTACGGCCTGAGTCCGTCCCAGCTGTCCGCCTCCGGGGACTTCACATACAGCGACGGAAAGACTTACACCATCACCCACGGCTCTGTTATCATAGCGGCCATAACTTCGTGCACGAACACGTCCAATCCAAGCGTGATGCTCGGAGCTGGGCTCCTCGCAAAGAAAGCCGTTGAGAATGGACTATCCGTTCTTCCGTATATCAAGACATCGCTGTCTCCGGGCTCCGGAGTGGTCACGTATTATCTAAGGGAGTCTGGGGTGGTCCCGTACCTGGAGAAGCTCGGCTTCAACACGGTGGGCTACGGGTGCATGACCTGCATCGGCAACTCCGGACCCATCGACGACAACATCGCGAACACCATCGAAAAGAACGAGCTAGTCTGCTGCGGCATCCTGTCCGGGAACAGAAACTTCGAGGGCCGCATCCACCCGAACACCAGAGCCAACTACCTGGCGTCTCCGCTGCTCGTCATAGCCTACGCGCTGGCCGGGACCGTGGACGTGGACTTCGAGACCGAACCATTGGGGAAGCGCCCCGACGGCTCGGCGGTGTACCTGCGCGACATCTGGCCCACCCGCGCGGAGATACAGCGCGTCGAGAACCAGTTCGTCATCCCCGGGATGTTTAAGGAGGTGTACGCGCGGATCGAGCAGGGCTCGGCGGCGTGGCAGGCGCTGGACGTGCCGCGCGGCCGCCTGTACAGCTGGGACGCGAACTCCACCTACATCAAGAAGCCCCCATTTTTCGACGGAATGACCAAGGAGCTGCCGGCGGCGACGAGCGTGCGGGGCGCGCGCTGCCTGCTGCTGCTGGGCGACTCGGTGACCACGGATCACATCTCGCCGGCGGGATCCATCGCGCGGAACTCGCCAGCAGCGAGATACCTCGCGCAGCGCGGGCTGACAGCCAGGGAGTTCAACTCGTACGGATCTCGGCGCGGGAACGACGCGGTGATGTCCAGGGGCACGTTTGCGAACATCCGCATCGTCAACAAGATGGCGCCGGCCCCCGGACCCAAGACCACGCACCACCCCTCCGGTGACGTCATGGACATCTTCGATGCTGCCGAGAGATACGCGTCAGAGGACGTCCCCCTCATTGCCATCGTCGGGAAGGACTACGGATCCGGGTCCAGCCGGGACTGGGCGGCCAAAGGACCTTACCTCCTGGGCATAAAGGCGGTGATAGCGGAGTCGTTCGAGCGGATCCATCGCTCGAACCTGGTCGGGATGGGTCTCCTCCCGCTGCAGTTCCTGCCCGGGGAGAGCGCGGCCACGCTCGGGCTGACGGGGGCGGAGCGCTACGACATCATCCTGCCGCCCGCGCTGGCGCCCGGCCAGACCGCGACCGTACAGGTGGACAACGGCACCTCGTTCCAGGTGGTCGTACGGTTCGACACGGAAGTCGACCTGACCTACTTCAAGAACGGCGGCATCTTGAACTACATGGTGCGAAAGATGCTTTGA

Protein

MAGSTNPYQKLLKTIEINGSTYTYYDVSALGPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVSNVLDWESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINGLGVVGWGVGGIEAEAVMLGQAISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKRPQDRVSVAIMKKDFQDCLTNKVGFKGYGLSPSQLSASGDFTYSDGKTYTITHGSVIIAAITSCTNTSNPSVMLGAGLLAKKAVENGLSVLPYIKTSLSPGSGVVTYYLRESGVVPYLEKLGFNTVGYGCMTCIGNSGPIDDNIANTIEKNELVCCGILSGNRNFEGRIHPNTRANYLASPLLVIAYALAGTVDVDFETEPLGKRPDGSAVYLRDIWPTRAEIQRVENQFVIPGMFKEVYARIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRGARCLLLLGDSVTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTFANIRIVNKMAPAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALAPGQTATVQVDNGTSFQVVVRFDTEVDLTYFKNGGILNYMVRKML

Similarity

Belongs to the aconitase/IPM isomerase family.

Uniprot

Q95UT2   A0A0N1ICI4   A0A182YMN5   A0A2M4BCZ4   A0A0T6B1Q5   A0A182KQS4   + More
A0A182I2U1   A0A182FG79   A0A084VQU9   A0A182XLN0   A0A182P233   Q7PTD5   A0A182U6J4   A0A2M3Z2L1   A0A182UU67   A0A2M3Z2M2   A0A2M3Z2G1   A0A182G243   A0A182WJN7   A0A182J569   V5SIW4   A0A182QZY5   A0A2M3Z2H5   W5J7Y2   A0A182JTP3   A0A182MKI4   A0A336K935   A0A1Q3FHT6   B0W3V2   A0A2M4A7J8   A0A2M4A737   U5EXZ9   A0A182NKQ2   A0A182RTW6   Q16ZG5   Q6SYX7   E2I8U2   A0A224XJ57   A0A1L8E113   T1PH68   A0A1L8E0X1   B3LZR4   A0A1W4U8E0   A0A1L8E0L4   A0A171AJH3   A0A023F4H4   A0A0L0CEH4   A0A1Y1NJP8   B4K5J4   A0A1I8Q0Q1   A0A1W4V9A0   B3P1N3   B3LVY9   Q9VGZ3   B4LWE7   A0A0C9QGU2   Q9NFX2   D6WKP6   B4HIT4   C7LA95   A0A0P4VTU7   B4QV81   A0A3B0KR23   A0A0V0G5N1   A0A3L8DIG1   B4PKQ0   A0A0R3NFK1   A0A146M1J6   A0A0A9XYB8   A0A0K8SKP8   B4G695   W8C1P3   Q29AM0   B4R0Q1   Q9NFX3   Q9VCV4   A0A1A9UJQ0   B4G5W3   Q29AT7   A0A1B0G521   A0A1B0BEI3   O76934   A0A1A9XG55   A0A1A9Z9L8   B3P8K5   B4HES8   A0A1A9WY36   A0A0A1XPN2   B4NF60   B4JIK1   A0A232FEF8   E0VUE0   O76935   A0A034WDC5   A0A158NVH9   B4N9Q5   B4N8W8   A0A0K8UFW6   A0A0M4EW31   A0A0K8V3H4  

Pubmed

26354079    25244985    20966253    24438588    12364791    14747013    + More
17210077    26483478    20920257    23761445    17510324    11891134    22075242    25315136    17994087    25474469    26108605    28004739    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    16679315    18362917    19820115    27129103    30249741    17550304    15632085    26823975    25401762    24495485    26109357    26109356    9660175    25830018    28648823    20566863    25348373    21347285   

EMBL

AY032658    AAK39637.1    KQ458725    KPJ05353.1    GGFJ01001775    MBW50916.1    + More
LJIG01016202    KRT81308.1    APCN01000180    ATLV01015326    KE525006    KFB40343.1    AAAB01008807    EAA04062.5    GGFM01002006    MBW22757.1    GGFM01002009    MBW22760.1    GGFM01001958    MBW22709.1    JXUM01039168    KQ561193    KXJ79410.1    KF647630    AHB50492.1    AXCN02000544    GGFM01001959    MBW22710.1    ADMH02002078    ETN59498.1    AXCM01004784    UFQS01000217    UFQT01000217    SSX01476.1    SSX21856.1    GFDL01007914    JAV27131.1    DS231833    EDS32249.1    GGFK01003287    MBW36608.1    GGFK01003295    MBW36616.1    GANO01000678    JAB59193.1    CH477491    EAT40025.1    AY445078    AAR15297.1    HM443949    ADN95939.1    GFTR01008253    JAW08173.1    GFDF01001899    JAV12185.1    KA647238    AFP61867.1    GFDF01001770    JAV12314.1    CH902617    EDV43058.1    GFDF01001898    JAV12186.1    GEMB01000992    JAS02153.1    GBBI01002291    JAC16421.1    JRES01000501    KNC30651.1    GEZM01001113    JAV98152.1    CH933806    EDW14031.2    CH954181    EDV49632.1    EDV41522.2    AE014297    AAF54529.1    CH940650    EDW66584.1    GBYB01013808    JAG83575.1    AY113650    AJ252017    AAM29655.1    CAB93520.1    KQ971342    EFA02996.1    CH480815    EDW42731.1    BT099645    ACV04815.1    GDKW01000650    JAI55945.1    CM000364    EDX13487.1    OUUW01000013    SPP87681.1    GECL01002806    JAP03318.1    QOIP01000007    RLU20245.1    CM000160    EDW96809.1    CM000070    KRS99928.1    GDHC01006169    JAQ12460.1    GBHO01019746    JAG23858.1    GBRD01012449    JAG53375.1    CH479179    EDW23854.1    GAMC01010961    JAB95594.1    EAL27329.3    EDX13974.1    AJ252016    CAB93519.1    AY058657    AAF56051.1    AAL13886.1    EDW23742.1    EAL27262.2    CCAG010003680    JXJN01012899    AJ223247    CAA11211.1    CH954182    EDV54100.1    EDW43239.1    GBXI01001497    JAD12795.1    CH964251    EDW82927.2    CH916369    EDV93082.1    NNAY01000342    OXU29052.1    DS235786    EEB16996.1    AJ223248    CAA11212.1    GAKP01006817    JAC52135.1    ADTU01027159    CH964232    EDW80620.2    EDW80473.2    GDHF01026765    JAI25549.1    CP012526    ALC47667.1    GDHF01018837    JAI33477.1   

Proteomes

UP000053268    UP000076408    UP000075882    UP000075840    UP000069272    UP000030765    + More
UP000076407    UP000075885    UP000007062    UP000075902    UP000075903    UP000069940    UP000249989    UP000075920    UP000075880    UP000075886    UP000000673    UP000075881    UP000075883    UP000002320    UP000075884    UP000075900    UP000008820    UP000095301    UP000007801    UP000192221    UP000037069    UP000009192    UP000095300    UP000008711    UP000000803    UP000008792    UP000007266    UP000001292    UP000000304    UP000268350    UP000279307    UP000002282    UP000001819    UP000008744    UP000078200    UP000092444    UP000092460    UP000092443    UP000092445    UP000091820    UP000007798    UP000001070    UP000215335    UP000009046    UP000005205    UP000092553   

PRIDE

Q9VGZ3    Q9NFX2    C7LA95    Q9NFX3    Q9VCV4    O76934    + More
O76935   

Pfam

PF00330   Aconitase        + More
PF00694   Aconitase_C

Interpro

IPR029784   IRE-BP1        + More
IPR036008   Aconitase_4Fe-4S_dom       
IPR018136   Aconitase_4Fe-4S_BS       
IPR000573   AconitaseA/IPMdHydase_ssu_swvl       
IPR015928   Aconitase/3IPM_dehydase_swvl       
IPR006249   Aconitase/IRP2       
IPR015931   Acnase/IPM_dHydase_lsu_aba_1/3       
IPR001030   Acoase/IPM_deHydtase_lsu_aba       

SUPFAM

SSF53732   SSF53732       

Gene 3D

3.20.19.10     3.30.499.10    

ProteinModelPortal

Q95UT2   A0A0N1ICI4   A0A182YMN5   A0A2M4BCZ4   A0A0T6B1Q5   A0A182KQS4   + More
A0A182I2U1   A0A182FG79   A0A084VQU9   A0A182XLN0   A0A182P233   Q7PTD5   A0A182U6J4   A0A2M3Z2L1   A0A182UU67   A0A2M3Z2M2   A0A2M3Z2G1   A0A182G243   A0A182WJN7   A0A182J569   V5SIW4   A0A182QZY5   A0A2M3Z2H5   W5J7Y2   A0A182JTP3   A0A182MKI4   A0A336K935   A0A1Q3FHT6   B0W3V2   A0A2M4A7J8   A0A2M4A737   U5EXZ9   A0A182NKQ2   A0A182RTW6   Q16ZG5   Q6SYX7   E2I8U2   A0A224XJ57   A0A1L8E113   T1PH68   A0A1L8E0X1   B3LZR4   A0A1W4U8E0   A0A1L8E0L4   A0A171AJH3   A0A023F4H4   A0A0L0CEH4   A0A1Y1NJP8   B4K5J4   A0A1I8Q0Q1   A0A1W4V9A0   B3P1N3   B3LVY9   Q9VGZ3   B4LWE7   A0A0C9QGU2   Q9NFX2   D6WKP6   B4HIT4   C7LA95   A0A0P4VTU7   B4QV81   A0A3B0KR23   A0A0V0G5N1   A0A3L8DIG1   B4PKQ0   A0A0R3NFK1   A0A146M1J6   A0A0A9XYB8   A0A0K8SKP8   B4G695   W8C1P3   Q29AM0   B4R0Q1   Q9NFX3   Q9VCV4   A0A1A9UJQ0   B4G5W3   Q29AT7   A0A1B0G521   A0A1B0BEI3   O76934   A0A1A9XG55   A0A1A9Z9L8   B3P8K5   B4HES8   A0A1A9WY36   A0A0A1XPN2   B4NF60   B4JIK1   A0A232FEF8   E0VUE0   O76935   A0A034WDC5   A0A158NVH9   B4N9Q5   B4N8W8   A0A0K8UFW6   A0A0M4EW31   A0A0K8V3H4  

PDB

2B3Y     E-value=0,     Score=3146

KEGG

101740956    K01681 aconitate hydratase [EC:4.2.1.3] | (RefSeq) cytoplasmic aconitate hydratase-like

PATHWAY

00020    Citrate cycle (TCA cycle) - Bombyx mori (domestic silkworm)
00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
01210    2-Oxocarboxylic acid metabolism - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)

GO

GO:0005737   GO:0006879   GO:0010040   GO:0003994   GO:0051539   GO:0006101   GO:0006099   GO:0005829   GO:0005739   GO:0030350   GO:0007370   GO:0008152   GO:0007165   GO:0005634   GO:0008270   GO:0003924   GO:0016020   GO:0003677   GO:0000723   GO:0006260  

PANTHER

PTHR11670   PTHR11670:SF32  

Subcellular location

Cytoplasm  

Length:

892

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.47657

Exp number, first 60 AAs:

0.00114

Total prob of N-in:

0.01985

outside

1  -  892

 

 

Pi

23.978543

Theta

162.359872

Tajima's D

1.973412

CLR

0.46464

CSRT

0.87975601219939

Interpretation

Uncertain