Gene

KWMTBOMO06069

Pre Gene Modal

BGIBMGA002851

Annotation

PREDICTED:_probable_G-protein_coupled_receptor_Mth-like_1_[Amyelois_transitella]

Location

Bomo_Chr10(-):17542269-17545084      View in EpiBrowser

Full name

Probable G-protein coupled receptor Mth-like 1      

Alternative Name

Protein methuselah-like 1

Location in the cell

PlasmaMembrane   Reliability : 3.907

CDS

ATGCTGGCGACTCTCGGCGTCGTGGTCGCGTGGACAGTGTGCTGGGTGTCAGCGGGCGGCGCGCACTCCCAACCTCTCTCTATTCCGCGCTGCTGTCCCGCCGGCCTCAGCCTCGATCTTGCGGCGCTCAGTGCGCTCGTGATCACCCCCGCCGCTGTGCCCTCGGCCTGTGTGCCCCAGACTGATCTTCAGCAAAAATGGGTACCGCTCGTGTACGGGCCGGTCGTGGGACGCTTCTTGGAGCGTGGTCGTTTGCCCGCACAGTGGAAGTTTCGCGACGCGACCGTCCCGAATTGCAAGGAGCTCCAGATCATTCCAGAACACGCGGCTGCTTACGCGCTTCTCAGAAATGACGGCTCTCTAATGATGATCCGGAGTAGAGGACGAGCGCTGGCCTTGTCGCGATACTGCACGGATGCCGCTGCAGCCCTCGTGTGCGCCGAGGATGTCACGCACACGTTATCCAAGTGTTGTGGCGAGGGACGAGTGTTTGACGGTGGCCATTGTATCTTGAACGAGTCCAAGTCTGTTGAGGTTCTTGCGGAACTGCGGAAATTAGCTAACGGCACCGTCGTCGGAGGCGGGTGGCCCACATGCGTCGCCGGCTTGAGCTACGGGGTGACGGGCGCCCTGAGCGGAGCCGTGCTGATGCCGGACGGCGCGCTAGAACTTAGTGGCACCAAGCTAGAGGCGGGTGCGTGGTGTGCAGAAGCAGTGGTGGGTGAGGAGGGCACGCGCATTTTGACTTGCGAAGCGGTGGCGAGCGCGGTGGTCCCGCGGCGGACAGCTCGGCACGCGCTCTACGGTGCAGGGCTGGCTGTGGGCGCGGCGTTCCTGGCCGCCACGCTGGCGGCTGGATTCGCGCTGCCGGCGGCTCACCACGCGCTGCACTGGCGGTGCCAGACGCACTATGTGGCGGCGCTGATGCTGGGCGACGTGCTGCTGGCGGCGACGCAGCTGGCCGACAACTCCGTGCCGCCGACATTGTGTCGCGCGCTAGCGGTCTGCATGCACTTCTTGTTCCTGTCCGCGTTCTTCTGGCTCAACACGATGTGTTTCAACATTTGGTGGACGTTCCGGGACTTCCGCCCGACCTCGCTGGAACGCGGCCAGGAGGCGTGGCGCCTCCGCGTGTACATGGTGTACGCGTGGGGCGGGCCGCTGCTGGTGGCCGGCACCGGCGCCCTGCTCGACCACCTGCCGGCCGGCGCCGCGCCTCTGCTGCGGCCGCGCTTCGCCGTGCAGCGTTGCTGGTTTTATGGTGACATGGAGATTCTCGTCTACTTCTTCGGTCCTGTGGGCGTCTTGCTTCTGGTCAATCTTGCACTCTTCATTTCTACCACGCGCCAGCTGACCTGCGGCCTCTGGCGGCGCGATGAGGTCAAGTCTACATCCGAGAGGGCAGCTTTGGGACGCGTGTGTGCCAAGCTGGTAGTAGTGATGGGCGTGACGTGGGGTGCGGATGTGGTGTCGTGGGCGGCGGGCGGGCCGGAGTACGTGTGGTACGCGACGGATCTGCTCAATGCTCTCCAGGGCGTGCTCATCTTCCTGGTGGTGGGGTGTCAACCGCACGCCTGGGCAGCGCTGAAGCGGTGTGCTGCGGCGTGCTGCGCGAAGGGCGGCAGCGGAGGCGGAGAGCGGGGCGCGGGCCGCCACTCCTCGACGCACCTGCCGTCCTGTGGGGAATCTCTGACGCACACCACGCAGGCCGCCGCCCCGGCCCCTGCGCCAGTACCTACACCCCGCGTCCCCATGGAGACGGTCTGCTGA

Protein

MLATLGVVVAWTVCWVSAGGAHSQPLSIPRCCPAGLSLDLAALSALVITPAAVPSACVPQTDLQQKWVPLVYGPVVGRFLERGRLPAQWKFRDATVPNCKELQIIPEHAAAYALLRNDGSLMMIRSRGRALALSRYCTDAAAALVCAEDVTHTLSKCCGEGRVFDGGHCILNESKSVEVLAELRKLANGTVVGGGWPTCVAGLSYGVTGALSGAVLMPDGALELSGTKLEAGAWCAEAVVGEEGTRILTCEAVASAVVPRRTARHALYGAGLAVGAAFLAATLAAGFALPAAHHALHWRCQTHYVAALMLGDVLLAATQLADNSVPPTLCRALAVCMHFLFLSAFFWLNTMCFNIWWTFRDFRPTSLERGQEAWRLRVYMVYAWGGPLLVAGTGALLDHLPAGAAPLLRPRFAVQRCWFYGDMEILVYFFGPVGVLLLVNLALFISTTRQLTCGLWRRDEVKSTSERAALGRVCAKLVVVMGVTWGADVVSWAAGGPEYVWYATDLLNALQGVLIFLVVGCQPHAWAALKRCAAACCAKGGSGGGERGAGRHSSTHLPSCGESLTHTTQAAAPAPAPVPTPRVPMETVC

Similarity

Belongs to the G-protein coupled receptor 2 family. Mth subfamily.

Keywords

Cell membrane   Complete proteome   Disulfide bond   G-protein coupled receptor   Glycoprotein   Membrane   Receptor   Reference proteome   Signal   Transducer   Transmembrane   Transmembrane helix  

Feature

chain  Probable G-protein coupled receptor Mth-like 1

Uniprot

H9J016   A0A212FED2   A0A2H1V6M5   A0A2Z5U769   A0A3S2NQW9   A0A2J7R7M9   + More
A0A3L8DAZ6   A0A067RCC7   A0A1Z1LVU5   A0A1B6JWB5   A0A0C9R8N0   A0A1J1HUF1   A0A158P3Z3   A0A1B6ENA3   A0A088AVM0   A0A1Q3FUM8   A0A1Q3FUF7   A0A1Q3FUW1   A0A1Q3FUJ4   A0A1Y1LEX7   A0A1Q3FUJ2   A0A1Q3FUS2   A0A2M4AJE5   A0A2M4DM51   A0A2M4DM29   A0A2M3Z501   D6X2H9   A0A0K8SSH1   A0A0A9W856   A0A2M4BHU4   A0A2M4BI25   A0A1B6MAP1   A0A2Y9D3P7   A0A2Y9D0W1   Q7PTM8   A0A0A7P873   A0A146KWL6   A0A1S4G5U6   A0A2M3Z6B7   A0A0A1X380   E0VBJ9   A0A0K8U803   A0A034VEF9   A0A2S2NLW8   A0A0K8VT68   J9K693   W8BGE8   A0A0M4F9I2   A0A2H8TZ60   B4MEK6   B4L1P8   A0A023EU51   B4PXV6   A0A336LR90   A0A336KT42   A0A1A9WWZ5   B4R5V6   A0A1A9X7T3   X2JC86   Q9VXD9   B4IEQ5   A0A1B0G4S0   A0A1B0ALN9   B3NVK0   A0A1A9UUD8   B3MQ68   A0A2S2QEF1   A0A1A9Z4Q7   A0A1I8QE85   B4NQ48   A0A1W4VJ42   A0A1I8MRA8   A0A084VPR6  

Pubmed

19121390    22118469    30249741    24845553    27685537    21347285    + More
28004739    18362917    19820115    25401762    26823975    12364791    14747013    17210077    25830018    20566863    25348373    24495485    17994087    18057021    24945155    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    10908591    25315136    24438588   

EMBL

BABH01018791    AGBW02008947    OWR52116.1    ODYU01000961    SOQ36505.1    AP017499    + More
BBB06786.1    RSAL01000349    RVE42280.1    NEVH01006727    PNF36848.1    QOIP01000010    RLU17494.1    KK852556    KDR21417.1    KX009474    ARW56807.1    GECU01004247    JAT03460.1    GBYB01012724    JAG82491.1    CVRI01000020    CRK90996.1    ADTU01008628    ADTU01008629    ADTU01008630    ADTU01008631    ADTU01008632    ADTU01008633    ADTU01008634    ADTU01008635    ADTU01008636    ADTU01008637    GECZ01030362    JAS39407.1    GFDL01003807    JAV31238.1    GFDL01003811    JAV31234.1    GFDL01003812    JAV31233.1    GFDL01003810    JAV31235.1    GEZM01062645    JAV69567.1    GFDL01003808    JAV31237.1    GFDL01003809    JAV31236.1    GGFK01007570    MBW40891.1    GGFL01014433    MBW78611.1    GGFL01014434    MBW78612.1    GGFM01002824    MBW23575.1    KQ971372    EFA10672.1    GBRD01009561    JAG56263.1    GBHO01038997    GDHC01019238    JAG04607.1    JAP99390.1    GGFJ01003484    MBW52625.1    GGFJ01003502    MBW52643.1    GEBQ01007053    JAT32924.1    APCN01004112    APCN01004113    AAAB01008797    EAA03645.2    KM588897    AJA06111.1    GDHC01019172    JAP99456.1    GGFM01003311    MBW24062.1    GBXI01009149    GBXI01002869    GBXI01000806    JAD05143.1    JAD11423.1    JAD13486.1    DS235032    EEB10755.1    GDHF01029540    GDHF01011421    JAI22774.1    JAI40893.1    GAKP01018462    GAKP01018461    GAKP01018460    JAC40492.1    GGMR01005157    MBY17776.1    GDHF01026200    GDHF01010240    JAI26114.1    JAI42074.1    ABLF02039939    GAMC01014199    GAMC01014198    GAMC01014197    GAMC01014196    JAB92356.1    CP012528    ALC48882.1    GFXV01007722    MBW19527.1    CH940664    EDW62981.1    CH933810    EDW06701.1    KRF93787.1    GAPW01001151    JAC12447.1    CM000162    EDX01942.2    UFQS01000047    UFQT01000047    SSW98531.1    SSX18917.1    UFQS01000912    UFQT01000912    SSX07619.1    SSX27957.1    CM000366    EDX18106.1    AE014298    AHN59810.1    AY118371    CH480832    EDW46159.1    CCAG010019908    JXJN01000025    JXJN01000026    CH954180    EDV46392.2    CH902621    EDV44494.1    GGMS01006868    MBY76071.1    CH964291    EDW86273.1    ATLV01015029    ATLV01015030    ATLV01015031    ATLV01015032    ATLV01015033    KE524999    KFB39960.1   

Proteomes

UP000005204    UP000007151    UP000283053    UP000235965    UP000279307    UP000027135    + More
UP000183832    UP000005205    UP000005203    UP000007266    UP000076407    UP000075840    UP000007062    UP000009046    UP000007819    UP000092553    UP000008792    UP000009192    UP000002282    UP000091820    UP000000304    UP000092443    UP000000803    UP000001292    UP000092444    UP000092460    UP000008711    UP000078200    UP000007801    UP000092445    UP000095300    UP000007798    UP000192221    UP000095301    UP000030765   

PRIDE

H9J016    X2JC86    Q9VXD9   

Pfam

PF00002   7tm_2        + More
PF06652   Methuselah_N

Interpro

IPR000832   GPCR_2_secretin-like        + More
IPR017981   GPCR_2-like       
IPR036272   Methuselah_N_sf       
IPR010596   Methuselah_N_dom       

SUPFAM

SSF63877   SSF63877       

ProteinModelPortal

H9J016   A0A212FED2   A0A2H1V6M5   A0A2Z5U769   A0A3S2NQW9   A0A2J7R7M9   + More
A0A3L8DAZ6   A0A067RCC7   A0A1Z1LVU5   A0A1B6JWB5   A0A0C9R8N0   A0A1J1HUF1   A0A158P3Z3   A0A1B6ENA3   A0A088AVM0   A0A1Q3FUM8   A0A1Q3FUF7   A0A1Q3FUW1   A0A1Q3FUJ4   A0A1Y1LEX7   A0A1Q3FUJ2   A0A1Q3FUS2   A0A2M4AJE5   A0A2M4DM51   A0A2M4DM29   A0A2M3Z501   D6X2H9   A0A0K8SSH1   A0A0A9W856   A0A2M4BHU4   A0A2M4BI25   A0A1B6MAP1   A0A2Y9D3P7   A0A2Y9D0W1   Q7PTM8   A0A0A7P873   A0A146KWL6   A0A1S4G5U6   A0A2M3Z6B7   A0A0A1X380   E0VBJ9   A0A0K8U803   A0A034VEF9   A0A2S2NLW8   A0A0K8VT68   J9K693   W8BGE8   A0A0M4F9I2   A0A2H8TZ60   B4MEK6   B4L1P8   A0A023EU51   B4PXV6   A0A336LR90   A0A336KT42   A0A1A9WWZ5   B4R5V6   A0A1A9X7T3   X2JC86   Q9VXD9   B4IEQ5   A0A1B0G4S0   A0A1B0ALN9   B3NVK0   A0A1A9UUD8   B3MQ68   A0A2S2QEF1   A0A1A9Z4Q7   A0A1I8QE85   B4NQ48   A0A1W4VJ42   A0A1I8MRA8   A0A084VPR6  

PDB

5UZ7     E-value=0.0120071,     Score=93

KEGG

101745169    K04599 G protein-coupled receptor Mth (Methuselah protein) | (RefSeq) probable G-protein coupled rec

GO

GO:0016021   GO:0004930   GO:0007166   GO:0007476   GO:0007509   GO:0070252   GO:0048383   GO:0043519   GO:0007472   GO:0007186   GO:0007369   GO:0008340   GO:0005886   GO:0042594   GO:0004888   GO:0016020   GO:0003677   GO:0000723   GO:0005634   GO:0006260  

Subcellular location

Cell membrane  

SignalP

Position:   1 - 23,         Likelihood:  0.936439

 

 

Length:

589

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

163.7515

Exp number, first 60 AAs:

14.76628

Total prob of N-in:

0.50984

POSSIBLE N-term signal

sequence

outside

1  -  266

TMhelix

267  -  289

inside

290  -  301

TMhelix

302  -  320

outside

321  -  334

TMhelix

335  -  357

inside

358  -  377

TMhelix

378  -  397

outside

398  -  424

TMhelix

425  -  447

inside

448  -  467

TMhelix

468  -  487

outside

488  -  506

TMhelix

507  -  529

inside

530  -  589

 

 

Pi

2.277868

Theta

3.951555

Tajima's D

-1.295233

CLR

11.859473

CSRT

0.0824458777061147

Interpretation

Uncertain