Gene

KWMTBOMO06055

Pre Gene Modal

BGIBMGA002845

Annotation

PREDICTED:_vacuolar_protein_sorting-associated_protein_13D-like_[Plutella_xylostella]

Location

Bomo_Chr10(+):17125296-17129114      View in EpiBrowser

Full name

Vacuolar protein sorting-associated protein 13D      

Location in the cell

Mitochondrial   Reliability : 1.839

CDS

ATGACAAAGGGGGGTATGACGTCACTGGTGAAACACAGCTACGAAGGCGCGACGCAGGAGGGGCTGGGAGGGTTCCTGACGGGGGTGGGGAAGGGGCTGGTGGGGACCGTCACCAAGCCTGTCATCGGCGTCCTCGACCTCGCTGCTGAGACGGCTTCGGCACTCAGGGACACCAGTCGAAGGTCGGACAAGTGGGTGCCGGCGCGGGTGCGCGGGCCGCGGTGCGCGTGGGGCGCGGGCTCCGCCCTGCCGCGCTACTGCGGGGCGCAGGCCCACGGCGCGGCGCTGCTGTACGCGCTCAACAACAACGACTACTCCGAGCGCTTCCTGGCCTACCGCATCGTCCGGGACACGCCGCACGACATCCGCGCGCTGCTCTCGGACTCCTACCTGCGCATCTTCACCTGCAAGCACTCTGCGCCGCAGGTCGTCATGGAGACGCACCTCAGCAACCTGGTGTCGTGCGCGGTGGTGGAGGCCGGCGGCGCGCAGCTGGTGGAGCTGGGCGTGCGCGGCGGCGAGGCGGGCGTGCGGCGGCCGCGCGTGCAGTGCGACTCGGCGGCGCTGGCGCGCTGGCTGCGCACGCACGCGCTGTACGCCGCGCAGCTCTACCACGAGCGGGCGCACACGCTGCTGCCGCCCGAGCCCGCACTCTGCGCGCCCGGGAACCATTAA

Protein

MTKGGMTSLVKHSYEGATQEGLGGFLTGVGKGLVGTVTKPVIGVLDLAAETASALRDTSRRSDKWVPARVRGPRCAWGAGSALPRYCGAQAHGAALLYALNNNDYSERFLAYRIVRDTPHDIRALLSDSYLRIFTCKHSAPQVVMETHLSNLVSCAVVEAGGAQLVELGVRGGEAGVRRPRVQCDSAALARWLRTHALYAAQLYHERAHTLLPPEPALCAPGNH

Description

Functions in promoting mitochondrial clearance by mitochondrial autophagy (mitophagy), also possibly by positively regulating mitochondrial fission (PubMed:29307555). Mitophagy plays an important role in regulating cell health and mitochondrial size and homeostasis (PubMed:29307555).

Similarity

Belongs to the VPS13 family.

Keywords

Complete proteome   Cytoplasm   Lectin   Lysosome   Reference proteome  

Feature

chain  Vacuolar protein sorting-associated protein 13D

Uniprot

A0A2H1V893   A0A2W1BLQ7   A0A2A4J3I8   A0A0L7L9Q2   A0A194Q3V3   A0A212FED5   + More
A0A2J7RLT2   A0A3S2LUG1   A0A2J7RLT0   A0A2J7RLV8   A0A1B6C7B3   A0A1Y1L7W2   A0A1B6D961   A0A1B6CRD8   A0A146KXH9   A0A0A9W7Q2   A0A0A9WG36   D6X361   N6TGW4   E0VE59   E9FVT2   A0A1B6CA12   A0A146MF30   T1I7N4   A0A232FP36   K7ITC6   A0A067QRL8   B4HG59   B4QRR2   A0A0J9UK05   A0A1B6MEQ3   B3M9D0   A0A0R1DXM4   Q9VU08   B4PGU5   E2BY65   A0A0L7QSM4   A0A2A3EG84   A0A1B6FCY4   A0A0M9A200   A0A1B6J1C2   A0A0P5M4A7   A0A0P5L7A1   A0A0P5KC92   A0A0P5KVU5   A0A0P6EQK7   A0A0P5L303   A0A0P5YV10   A0A0N8BKM7   A0A0P5PGL9   A0A0P5M5H5   A0A0N8AWY6   A0A0P5FY43   A0A0P5KFU5   A0A0P6EXV1   A0A0P5LEA2   A0A0P5LP71   A0A0P6FQM8   A0A0P6EDP8   A0A0P6GRV7   A0A0P5GFK9   A0A0P5NNC8   A0A0P5NDQ5   A0A0N8BUD2   A0A0P5NK87   A0A0N8ARY6   A0A0P5FY99   A0A0P5JRV7   A0A0N8EIS0   A0A0P5JJQ0   A0A0N8B217   A0A0P5I0D6   A0A0P5KIX8   A0A0P5L047   A0A0P6BL35   A0A0P6IBF0   A0A0P5PPU7   A0A0P5H3J7   A0A0N8E9P1   A0A0P5LFX4   A0A0P6FA87   A0A0P5RJZ5   A0A0P5JN25   A0A0P5NND2   A0A0P5QFL0   A0A0P6GTE3   A0A0P6E410   A0A0N8C0A0   A0A0P5MJQ0   A0A0P6D444   A0A0P5R6D8   A0A0P5S1F0   A0A0P5RSH3   A0A0P5HI48   A0A0N8BMH0   A0A0P5M8U8   A0A0P5P060   A0A0P5NH29  

Pubmed

28756777    26227816    26354079    22118469    28004739    26823975    + More
25401762    18362917    19820115    23537049    20566863    21292972    28648823    20075255    24845553    17994087    22936249    17550304    10731132    12537572    29604224    29307555    20798317   

EMBL

ODYU01001174    SOQ37029.1    KZ150039    PZC74595.1    NWSH01003638    PCG66010.1    + More
JTDY01002066    KOB72192.1    KQ459472    KPJ00217.1    AGBW02008947    OWR52102.1    NEVH01002683    PNF41792.1    RSAL01000192    RVE44644.1    PNF41791.1    PNF41789.1    GEDC01027911    JAS09387.1    GEZM01066271    JAV68025.1    GEDC01015106    GEDC01006474    JAS22192.1    JAS30824.1    GEDC01021320    JAS15978.1    GDHC01017701    JAQ00928.1    GBHO01039780    JAG03824.1    GBHO01039779    JAG03825.1    KQ971372    EFA09797.2    APGK01038542    KB740960    ENN77018.1    DS235088    EEB11665.1    GL732525    EFX89051.1    GEDC01026972    JAS10326.1    GDHC01001303    JAQ17326.1    ACPB03000178    ACPB03000179    ACPB03000180    NNAY01000006    OXU32127.1    AAZX01003330    KK853018    KDR12416.1    CH480815    EDW41305.1    CM000363    EDX10276.1    CM002912    KMY99285.1    GEBQ01005612    JAT34365.1    CH902618    EDV41143.2    CM000159    KRK01769.1    AE014296    EDW94334.2    GL451420    EFN79344.1    KQ414756    KOC61642.1    KZ288266    PBC30166.1    GECZ01021709    JAS48060.1    KQ435760    KOX75567.1    GECU01014743    JAS92963.1    GDIQ01172388    JAK79337.1    GDIQ01175636    JAK76089.1    GDIQ01186336    JAK65389.1    GDIQ01186337    GDIQ01186334    JAK65391.1    GDIQ01059233    JAN35504.1    GDIQ01175638    JAK76087.1    GDIP01053078    JAM50637.1    GDIQ01168443    JAK83282.1    GDIQ01128760    JAL22966.1    GDIQ01163297    JAK88428.1    GDIQ01235921    GDIQ01234771    JAK16954.1    GDIQ01248768    JAK02957.1    GDIQ01186335    JAK65390.1    GDIQ01056585    JAN38152.1    GDIQ01172390    JAK79335.1    GDIQ01175637    JAK76088.1    GDIQ01044641    JAN50096.1    GDIQ01078422    JAN16315.1    GDIQ01031045    JAN63692.1    GDIQ01248770    JAK02955.1    GDIQ01144005    JAL07721.1    GDIQ01144004    JAL07722.1    GDIQ01144003    JAL07723.1    GDIQ01144006    GDIQ01144002    JAL07720.1    GDIQ01248771    JAK02954.1    GDIQ01248774    GDIQ01248773    GDIQ01248772    GDIQ01248769    JAK02953.1    GDIQ01220524    JAK31201.1    GDIQ01022708    JAN72029.1    GDIQ01201928    JAK49797.1    GDIQ01220523    JAK31202.1    GDIQ01220527    GDIQ01220526    GDIQ01220525    JAK31200.1    GDIQ01184687    JAK67038.1    GDIQ01184688    GDIQ01184686    JAK67037.1    GDIP01016461    JAM87254.1    GDIQ01006963    JAN87774.1    GDIQ01136008    JAL15718.1    GDIQ01235872    JAK15853.1    GDIQ01048140    JAN46597.1    GDIQ01170143    JAK81582.1    GDIQ01063336    JAN31401.1    GDIQ01099668    JAL52058.1    GDIQ01200730    JAK50995.1    GDIQ01146754    JAL04972.1    GDIQ01136007    JAL15719.1    GDIQ01049639    JAN45098.1    GDIQ01080322    JAN14415.1    GDIQ01127459    JAL24267.1    GDIQ01162745    JAK88980.1    GDIQ01083023    JAN11714.1    GDIQ01112060    JAL39666.1    GDIQ01098316    JAL53410.1    GDIQ01105965    JAL45761.1    GDIQ01229271    JAK22454.1    GDIQ01163299    JAK88426.1    GDIQ01163296    JAK88429.1    GDIQ01145407    JAL06319.1    GDIQ01145405    JAL06321.1   

Proteomes

UP000218220    UP000037510    UP000053268    UP000007151    UP000235965    UP000283053    + More
UP000007266    UP000019118    UP000009046    UP000000305    UP000015103    UP000215335    UP000002358    UP000027135    UP000001292    UP000000304    UP000007801    UP000002282    UP000000803    UP000008237    UP000053825    UP000242457    UP000053105   

PRIDE

Q9VU08   

Pfam

PF16909   VPS13_C        + More
PF06650   SHR-BD
PF12624   Chorein_N
PF16908   VPS13
PF16910   VPS13_mid_rpt
PF00627   UBA

Interpro

IPR026847   VPS13        + More
IPR031645   VPS13_C       
IPR009543   SHR-BD       
IPR026854   VPS13_N       
IPR031642   VPS13_mid_rpt       
IPR031646   VPS13_N2       
IPR015940   UBA       
IPR041969   VP13D_UBA       
IPR009060   UBA-like_sf       
IPR035992   Ricin_B-like_lectins       
IPR000772   Ricin_B_lectin       

SUPFAM

SSF50370   SSF50370        + More
SSF46934   SSF46934       

CDD

cd14306  UBA_VP13D
cd00161  RICIN

ProteinModelPortal

A0A2H1V893   A0A2W1BLQ7   A0A2A4J3I8   A0A0L7L9Q2   A0A194Q3V3   A0A212FED5   + More
A0A2J7RLT2   A0A3S2LUG1   A0A2J7RLT0   A0A2J7RLV8   A0A1B6C7B3   A0A1Y1L7W2   A0A1B6D961   A0A1B6CRD8   A0A146KXH9   A0A0A9W7Q2   A0A0A9WG36   D6X361   N6TGW4   E0VE59   E9FVT2   A0A1B6CA12   A0A146MF30   T1I7N4   A0A232FP36   K7ITC6   A0A067QRL8   B4HG59   B4QRR2   A0A0J9UK05   A0A1B6MEQ3   B3M9D0   A0A0R1DXM4   Q9VU08   B4PGU5   E2BY65   A0A0L7QSM4   A0A2A3EG84   A0A1B6FCY4   A0A0M9A200   A0A1B6J1C2   A0A0P5M4A7   A0A0P5L7A1   A0A0P5KC92   A0A0P5KVU5   A0A0P6EQK7   A0A0P5L303   A0A0P5YV10   A0A0N8BKM7   A0A0P5PGL9   A0A0P5M5H5   A0A0N8AWY6   A0A0P5FY43   A0A0P5KFU5   A0A0P6EXV1   A0A0P5LEA2   A0A0P5LP71   A0A0P6FQM8   A0A0P6EDP8   A0A0P6GRV7   A0A0P5GFK9   A0A0P5NNC8   A0A0P5NDQ5   A0A0N8BUD2   A0A0P5NK87   A0A0N8ARY6   A0A0P5FY99   A0A0P5JRV7   A0A0N8EIS0   A0A0P5JJQ0   A0A0N8B217   A0A0P5I0D6   A0A0P5KIX8   A0A0P5L047   A0A0P6BL35   A0A0P6IBF0   A0A0P5PPU7   A0A0P5H3J7   A0A0N8E9P1   A0A0P5LFX4   A0A0P6FA87   A0A0P5RJZ5   A0A0P5JN25   A0A0P5NND2   A0A0P5QFL0   A0A0P6GTE3   A0A0P6E410   A0A0N8C0A0   A0A0P5MJQ0   A0A0P6D444   A0A0P5R6D8   A0A0P5S1F0   A0A0P5RSH3   A0A0P5HI48   A0A0N8BMH0   A0A0P5M8U8   A0A0P5P060   A0A0P5NH29  

KEGG

101745111    no KO assigned | (RefSeq) protein jim lovell-like

GO

GO:0007005   GO:0005623   GO:0019898   GO:0045053   GO:0006623   GO:0005764   GO:0070530   GO:0043130   GO:0000423   GO:0030246  

PANTHER

PTHR16166  

Subcellular location

Cytoplasm  
Lysosome  

Length:

224

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.21666

Exp number, first 60 AAs:

0.20863

Total prob of N-in:

0.06003

outside

1  -  224

 

 

Pi

14.066319

Theta

14.173352

Tajima's D

-0.575913

CLR

1.017599

CSRT

0.217639118044098

Interpretation

Uncertain