Gene

KWMTBOMO06048

Pre Gene Modal

BGIBMGA002841

Annotation

caspase_Nc_[Bombyx_mori]

Location

Bomo_Chr10(+):17039096-17041242      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 1.791

CDS

ATGACAAAATTTTACATATACTTAAGACCGAGGCAGGGCTCGGACGCGCCCGTGCCGCCGCCGCCCGTGAACAGCAGTGAGCCGGTCGCCATCCCGTGCTTCCACGTGAAGAAGAGCACTCACTTCTTCGAGGACGATGTGAGCAGGGATATCCAGTTGTACCGCACGCGGAGCCGGAAGCGAGGAGTTCTAGTCGTGTTCAGCTACATTTCGTTCCTGCTGAACATCGAGCCCAACAGGGACGGGGTCAATGTGGACTGCGACAAGTTGAAGTACTTATTCTCAGAGATCGGCTTCGAGGTGCTCACTTACCAGAACTTGACTTTGGAGCAAACCCGCGCGACCCTGGAGCAGATGTCGTCGGTGCTGGCGGGCTACGAGTGCGTGTTCCTGGTGGTGTCGTCGCACGGCCACGAGCGCCGCTACTCCTCCGACACGGACATCCGCTGCAGCGACGGCAAGTTCATCTCGCTCTACGCCATCGTGGACTACTTCAACAACAGGAAGCTGCCCAACTTCACGGACCTCCCGAAGGTCTTCATCTTCCAAGCTTGCAGGGGCGAGAACGAGGACTTCGTGCAGGGCGGCGGAGCGCTGGCGCCGGCGCCGCAGGTGGCGCGGGACGGGGCGGTGCGGGCCCCCCGCGCGCCGCACCACCCCGCGCCCCTGCCGCTGCACCACGCCGAGAAGCCGCTCTACTCCAACATACTCATCGCTAACTCCACCCTCCCAGGGTTCATCTCCCACCGCGACGTGAAGGCCGGCTCCTGGTACATCCAGGTCCTGTGCGAAGTGTTCGCCGAGCGCGCCCACGACTGCCACGTGGACGAGCTGTTCACGCTGGTGGACAAGCGCCTGCGCCTGCGGTTCGGGCGGCAGACCTCCTCCGTGGACCGCTGGGGCTTCAACAACAAGCTGTACTTACACCCCGGTCTGTACGAGTGA

Protein

MTKFYIYLRPRQGSDAPVPPPPVNSSEPVAIPCFHVKKSTHFFEDDVSRDIQLYRTRSRKRGVLVVFSYISFLLNIEPNRDGVNVDCDKLKYLFSEIGFEVLTYQNLTLEQTRATLEQMSSVLAGYECVFLVVSSHGHERRYSSDTDIRCSDGKFISLYAIVDYFNNRKLPNFTDLPKVFIFQACRGENEDFVQGGGALAPAPQVARDGAVRAPRAPHHPAPLPLHHAEKPLYSNILIANSTLPGFISHRDVKAGSWYIQVLCEVFAERAHDCHVDELFTLVDKRLRLRFGRQTSSVDRWGFNNKLYLHPGLYE

Similarity

Belongs to the peptidase C14A family.

Uniprot

E0D2V3   H9J006   G0XQH2   E9JEG3   A0A2H4WW93   K7WJ03   + More
A0A2W1BPE7   G0XQH4   A0A2H1WTM5   A0A286M5H6   A0A2A4IVH1   R4I520   A0A0N1I6J1   M4NKN4   A0A194Q5C6   H3JZW6   G0XQH5   A0A212FNV6   A0A023J7Q9   W8DU35   A0A0L7LJ92   A0A1Y1JWU1   K7J0Y7   A0A1S4FTQ4   A0A1W4UN01   A0A232EQK8   A0A182GYM4   Q16PQ5   A0A2J7PU39   K7JH14   A0A1Q3FLD2   A0A1Q3FKV6   A0A2J7PU40   A0A1Q3FL48   A0A1Q3FKY6   B3M583   A0A1Q3FLA8   B4PDY8   A0A0M4EG02   A0A1W4WWI8   A0A182NNC1   B4LGM4   A0A0P4Y7Z4   A0A162DB86   A0A0P6BSY0   A0A0P6IEV2   A0A084WAJ9   B4MLX3   U5EYG7   B4J2U2   A0A182YI42   Q7Q2Q0   A0A182HXI0   A0A182M9Q2   A0A182WZV2   A0A182LI73   A0A182WCK7   A0A2M4AQU3   D6X3B3   A0A182P5Z6   A0A2M4CS65   A0A182FJA8   A0A2M4CSE3   T1GIG7   W5MP74   A0A0P4WPU1   A0A0R3X4P0   V5HTW6   A0A0P4WX74   V9KNT3   B0W757   H3D019   A0A3B3BI00   L7MJV8   A0A3B3BH50   L7MJ43   A0A2D0RE86   A0A3B4FSA4   Q4SC67   A0A212EUQ8   A0A3B3BQT0   A0A3B3D9Y2   A0A2J7PIQ1   A0A0P4VSE4   A0A1V4KP69   A0A1I8NVJ4   T1JVJ5   A0A3B3DJI8   A0A3B3C6K6   A0A2I0M343   A0A2R5LKV7   L7M0M7   A0A1B6E4V5  

Pubmed

19121390    21740565    21040523    28756777    26354079    23474489    + More
23743202    22118469    26227816    28004739    20075255    28648823    26483478    17510324    17994087    17550304    24438588    25244985    12364791    14747013    17210077    20966253    18362917    19820115    25765539    24402279    15496914    29451363    25576852    27129103    23371554   

EMBL

AB489117    BAJ16361.1    BABH01018851    HQ328976    AEK20833.1    GQ426280    + More
ADM32506.1    KY514095    AUD12126.1    JX840448    AFX60235.1    KZ150039    PZC74600.1    HQ328978    AEK20835.1    ODYU01010920    SOQ56332.1    KX827592    ASV64720.1    NWSH01007037    PCG63123.1    JQ768051    AFJ04535.1    KQ460784    KPJ12221.1    JX912275    AGG91491.1    KQ459472    KPJ00210.1    AB663140    BAL60586.1    HQ328979    AEK20836.1    AGBW02004392    OWR55428.1    KF365914    AHH02584.1    KC683711    AHF70712.1    JTDY01000902    KOB75500.1    GEZM01098696    JAV53794.1    NNAY01002753    OXU20628.1    JXUM01021201    KQ560594    KXJ81718.1    CH477774    EAT36368.1    NEVH01021208    PNF19850.1    GFDL01006759    JAV28286.1    GFDL01006911    JAV28134.1    PNF19849.1    GFDL01006832    JAV28213.1    GFDL01006873    JAV28172.1    CH902618    EDV40588.1    GFDL01006751    JAV28294.1    CM000159    EDW93984.1    CP012525    ALC43265.1    CH940647    EDW69462.1    GDIP01232240    JAI91161.1    LRGB01002066    KZS09434.1    GDIP01010428    JAM93287.1    GDIQ01005597    JAN89140.1    ATLV01022201    KE525330    KFB47243.1    CH963847    EDW73184.2    GANO01000312    JAB59559.1    CH916366    EDV96083.1    AAAB01008968    EAA13168.4    APCN01005306    AXCM01001478    GGFK01009819    MBW43140.1    KQ971372    EFA10766.1    GGFL01004006    MBW68184.1    GGFL01004007    MBW68185.1    CAQQ02392379    AHAT01036531    AHAT01036532    AHAT01036533    GDRN01052445    JAI66300.1    UYWX01020493    VDM32914.1    GANP01006785    JAB77683.1    GDRN01052446    JAI66299.1    JW867140    AFO99657.1    DS231852    EDS37662.1    GACK01001560    JAA63474.1    GACK01001731    JAA63303.1    CAAE01014659    CAG01765.1    AGBW02012322    OWR45225.1    NEVH01024980    PNF16221.1    GDKW01001744    JAI54851.1    LSYS01002427    OPJ86218.1    CAEY01000795    AKCR02000044    PKK24100.1    GGLE01006017    MBY10143.1    GACK01007143    JAA57891.1    GEDC01021987    GEDC01009282    GEDC01004338    JAS15311.1    JAS28016.1    JAS32960.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000037510    + More
UP000002358    UP000192221    UP000215335    UP000069940    UP000249989    UP000008820    UP000235965    UP000007801    UP000002282    UP000092553    UP000192223    UP000075884    UP000008792    UP000076858    UP000030765    UP000007798    UP000001070    UP000076408    UP000007062    UP000075840    UP000075883    UP000076407    UP000075882    UP000075920    UP000007266    UP000075885    UP000069272    UP000015102    UP000018468    UP000046396    UP000274429    UP000002320    UP000007303    UP000261560    UP000221080    UP000261460    UP000190648    UP000095300    UP000015104    UP000053872   

PRIDE

E0D2V3    H9J006    G0XQH2    E9JEG3   

Pfam

PF00619   CARD

Interpro

IPR001315   CARD        + More
IPR015917   Pept_C14A       
IPR029030   Caspase-like_dom_sf       
IPR033171   Caspase-9       
IPR001309   Pept_C14_p20       
IPR011029   DEATH-like_dom_sf       
IPR002398   Pept_C14       
IPR002138   Pept_C14_p10       
IPR033139   Caspase_cys_AS       
IPR016129   Caspase_his_AS       
IPR035702   Caspase_2       
IPR042147   CARD_CASP9       
IPR037554   Caspase_6       

SUPFAM

SSF47986   SSF47986        + More
SSF52129   SSF52129       

CDD

cd00032  CASc
cd08326  CARD_CASP9

ProteinModelPortal

E0D2V3   H9J006   G0XQH2   E9JEG3   A0A2H4WW93   K7WJ03   + More
A0A2W1BPE7   G0XQH4   A0A2H1WTM5   A0A286M5H6   A0A2A4IVH1   R4I520   A0A0N1I6J1   M4NKN4   A0A194Q5C6   H3JZW6   G0XQH5   A0A212FNV6   A0A023J7Q9   W8DU35   A0A0L7LJ92   A0A1Y1JWU1   K7J0Y7   A0A1S4FTQ4   A0A1W4UN01   A0A232EQK8   A0A182GYM4   Q16PQ5   A0A2J7PU39   K7JH14   A0A1Q3FLD2   A0A1Q3FKV6   A0A2J7PU40   A0A1Q3FL48   A0A1Q3FKY6   B3M583   A0A1Q3FLA8   B4PDY8   A0A0M4EG02   A0A1W4WWI8   A0A182NNC1   B4LGM4   A0A0P4Y7Z4   A0A162DB86   A0A0P6BSY0   A0A0P6IEV2   A0A084WAJ9   B4MLX3   U5EYG7   B4J2U2   A0A182YI42   Q7Q2Q0   A0A182HXI0   A0A182M9Q2   A0A182WZV2   A0A182LI73   A0A182WCK7   A0A2M4AQU3   D6X3B3   A0A182P5Z6   A0A2M4CS65   A0A182FJA8   A0A2M4CSE3   T1GIG7   W5MP74   A0A0P4WPU1   A0A0R3X4P0   V5HTW6   A0A0P4WX74   V9KNT3   B0W757   H3D019   A0A3B3BI00   L7MJV8   A0A3B3BH50   L7MJ43   A0A2D0RE86   A0A3B4FSA4   Q4SC67   A0A212EUQ8   A0A3B3BQT0   A0A3B3D9Y2   A0A2J7PIQ1   A0A0P4VSE4   A0A1V4KP69   A0A1I8NVJ4   T1JVJ5   A0A3B3DJI8   A0A3B3C6K6   A0A2I0M343   A0A2R5LKV7   L7M0M7   A0A1B6E4V5  

PDB

3J9K     E-value=1.8868e-26,     Score=295

KEGG

100500764    K20009 caspase Dronc [EC:3.4.22.-] | (RefSeq) Nc, Casp-5, Dronc; Nedd2-like caspase

PATHWAY

04214    Apoptosis - fly - Bombyx mori (domestic silkworm)
04215    Apoptosis - multiple species - Bombyx mori (domestic silkworm)

GO

GO:0006915   GO:0004197   GO:0042981   GO:0097200   GO:0022416   GO:0043293   GO:0010940   GO:0007291   GO:0097199   GO:2001269   GO:0010506   GO:0048749   GO:0006919   GO:0048813   GO:0046672   GO:0035234   GO:0008258   GO:0016540   GO:0007516   GO:0007417   GO:0016322   GO:0035006   GO:0051291   GO:0008340   GO:0031638   GO:0042803   GO:0035070   GO:0045476   GO:0008285   GO:0005737   GO:0097153   GO:0043065   GO:0008630   GO:0043281   GO:0097205   GO:0048696   GO:0001822   GO:0006508   GO:0008234   GO:0008026   GO:0016818   GO:0004003   GO:0003677   GO:0000723   GO:0005634   GO:0006260  

PANTHER

PTHR10454   PTHR10454:SF157   PTHR10454:SF151   PTHR10454:SF206  

Length:

314

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.51504

Exp number, first 60 AAs:

0.00426

Total prob of N-in:

0.05072

outside

1  -  314

 

 

Pi

5.016642

Theta

14.113231

Tajima's D

-1.510562

CLR

17.352465

CSRT

0.056347182640868

Interpretation

Uncertain