Gene

KWMTBOMO05990  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002887

Annotation

putative_mediator_complex?_subunit_[Operophtera_brumata]

Location

Bomo_Chr10(-):15868803-15870027      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 19      

Alternative Name

Mediator complex subunit 19

Location in the cell

Nuclear   Reliability : 3.653

CDS

ATGGACTTGTACATTCTTACATTGGCAGGTTTTCGATTACACCCTGGCCCACTTCCTGAGCAGTACAGATATGTGAGTGCAACACCACCAAAGCGACATAAAAGCAAACATAAGAAACATAAGCATAAAGATGGTGCACCTCCTGGGCAAGAGACACCTTTACAAGATTCATCAAATCCAGACACATATGAGAAAAAGCATAAGAAGCAAAAACGTCATGACGATGAGAAAGAACGAAAGAAGAGAAAAAAAGAGAAAAAGAGAAAAAAGCAAAAACACAGCCCTGAGCATGGAGGCCTTACACCAAACCAACATCCATTACCGTAA

Protein

MDLYILTLAGFRLHPGPLPEQYRYVSATPPKRHKSKHKKHKHKDGAPPGQETPLQDSSNPDTYEKKHKKQKRHDDEKERKKRKKEKKRKKQKHSPEHGGLTPNQHPLP

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Subunit

Component of the Mediator complex.

Similarity

Belongs to the Mediator complex subunit 19 family.

Keywords

Activator   Complete proteome   Nucleus   Reference proteome   Transcription   Transcription regulation  

Feature

chain  Mediator of RNA polymerase II transcription subunit 19

Uniprot

H9J052   A0A0L7KN74   A0A212FKU8   A0A2H1VTG2   A0A2A4JN82   A0A194Q579   + More
A0A194QR54   S4PCQ4   A0A3S2PLM1   J3JXL7   V5FU46   D6X2R5   A0A2P8XVX2   A0A2J7QTT1   A0A067QMD3   A0A1Y1LHW8   A0A0T6AZD3   A0A1W4X1H4   A0A1B6C6N5   A0A232FEG4   K7J2X3   A0A154P4X7   A0A0C9QFR1   A0A0L7R5E2   A0A2A3ENM5   A0A088A195   A0A310SLD6   A0A1B6JEJ4   A0A026WJN3   A0A151IJY8   A0A195EHG0   A0A195B043   A0A195FBK6   A0A158NKH3   F4WWI6   A0A151WT56   E9IWZ9   A0A0J7K6L3   A0A1L8DFG8   E1ZZZ9   A0A0A9XAP2   E2B310   A0A182YNH6   A0A182H615   A0A1B0C7Z6   A0A182SNJ8   Q174D3   A0A1W7R5I8  

Pubmed

19121390    26227816    22118469    26354079    23622113    22516182    + More
23537049    18362917    19820115    29403074    24845553    28004739    28648823    20075255    24508170    30249741    21347285    21719571    21282665    20798317    25401762    26823975    25244985    26483478    17510324   

EMBL

BABH01018957    JTDY01008722    KOB64429.1    AGBW02007959    OWR54371.1    ODYU01004342    + More
SOQ44109.1    NWSH01001058    PCG72872.1    KQ459472    KPJ00160.1    KQ461175    KPJ07988.1    GAIX01004051    JAA88509.1    RSAL01000002    RVE54963.1    APGK01022463    BT127986    KB740424    KB632191    AEE62948.1    ENN80694.1    ERL89868.1    GALX01007301    JAB61165.1    KQ971372    EFA09832.1    PYGN01001265    PSN36146.1    NEVH01011193    PNF31973.1    KK853248    KDR09356.1    GEZM01057075    GEZM01057074    JAV72458.1    LJIG01022506    KRT80213.1    GEDC01028135    GEDC01013876    JAS09163.1    JAS23422.1    NNAY01000356    OXU28943.1    KQ434819    KZC06903.1    GBYB01013328    JAG83095.1    KQ414652    KOC66097.1    KZ288215    PBC32729.1    KQ764881    OAD54359.1    GECU01010020    JAS97686.1    KK107183    QOIP01000011    EZA55881.1    RLU16788.1    KQ977294    KYN03958.1    KQ978881    KYN27708.1    KQ976692    KYM77848.1    KQ981693    KYN37761.1    ADTU01018838    GL888406    EGI61439.1    KQ982762    KYQ51079.1    GL766616    EFZ14943.1    LBMM01012762    KMQ86007.1    GFDF01008891    JAV05193.1    GL435531    EFN73239.1    GBHO01025802    GBRD01002127    GDHC01015050    JAG17802.1    JAG63694.1    JAQ03579.1    GL445250    EFN89979.1    JXUM01113218    KQ565669    KXJ70792.1    AJWK01000030    AJWK01000031    CH477413    GEHC01001198    JAV46447.1   

Proteomes

UP000005204    UP000037510    UP000007151    UP000218220    UP000053268    UP000053240    + More
UP000283053    UP000019118    UP000030742    UP000007266    UP000245037    UP000235965    UP000027135    UP000192223    UP000215335    UP000002358    UP000076502    UP000053825    UP000242457    UP000005203    UP000053097    UP000279307    UP000078542    UP000078492    UP000078540    UP000078541    UP000005205    UP000007755    UP000075809    UP000036403    UP000000311    UP000008237    UP000076408    UP000069940    UP000249989    UP000092461    UP000075901    UP000008820   

PRIDE

H9J052    Q174D3   

Pfam

PF10278   Med19

Interpro

IPR019403   Mediator_Med19_met       

ProteinModelPortal

H9J052   A0A0L7KN74   A0A212FKU8   A0A2H1VTG2   A0A2A4JN82   A0A194Q579   + More
A0A194QR54   S4PCQ4   A0A3S2PLM1   J3JXL7   V5FU46   D6X2R5   A0A2P8XVX2   A0A2J7QTT1   A0A067QMD3   A0A1Y1LHW8   A0A0T6AZD3   A0A1W4X1H4   A0A1B6C6N5   A0A232FEG4   K7J2X3   A0A154P4X7   A0A0C9QFR1   A0A0L7R5E2   A0A2A3ENM5   A0A088A195   A0A310SLD6   A0A1B6JEJ4   A0A026WJN3   A0A151IJY8   A0A195EHG0   A0A195B043   A0A195FBK6   A0A158NKH3   F4WWI6   A0A151WT56   E9IWZ9   A0A0J7K6L3   A0A1L8DFG8   E1ZZZ9   A0A0A9XAP2   E2B310   A0A182YNH6   A0A182H615   A0A1B0C7Z6   A0A182SNJ8   Q174D3   A0A1W7R5I8  

KEGG

101738557    K15137 mediator of RNA polymerase II transcription subunit 19 | (RefSeq) mediator of RNA polymerase

GO

GO:0016592   GO:0006357   GO:0003712   GO:0005634   GO:0008134   GO:0045944   GO:0006412   GO:0005622   GO:0008270   GO:0006508   GO:0007264   GO:0008026   GO:0016597  

Subcellular location

Nucleus  

Length:

108

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00047

Exp number, first 60 AAs:

0.00047

Total prob of N-in:

0.06222

outside

1  -  108

 

 

Pi

11.214126

Theta

11.118933

Tajima's D

-0.224671

CLR

4.416075

CSRT

0.31628418579071

Interpretation

Uncertain